Patterns of Local Recurrence and Oncologic Outcomes in T3 Low Rectal Cancer (≤5 cm from the Anal Verge) Treated With Short-Course Radiotherapy With Delayed Surgery : Outcomes in T3 Low Rectal Cancer Treated With Short-Course Radiotherapy With Delayed Surg

abstract：BACKGROUND:In patients with colorectal hepatic metastases, response rates with hepatic arterial infusion (HAI) FUdR (5-Fluoro-2-deoxyuridine) are significantly higher than with systemic fluoropyrimidines. We report a novel animal model of intrahepatic therapy for hepatic metastasis for the study of methods to increase ...

journal_title：Annals of surgical oncology

authors： Sutanto-Ward E,Arisawa Y,Tremiterra S,Sigurdson ER

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The combination of neoadjuvant radiochemotherapy and parenchyma-preserving sleeve resection for lung cancer remains controversial because of potentially increased rate of anastomotic breakdown. We analyzed the effects of applying a decellularized human dermis transplant seeded with autologous fibroblasts in ...

journal_title：Annals of surgical oncology

authors： Roessner E,Vitacolonna M,Schulmeister A,Pilz L,Tsagogiorgas C,Brockmann M,Hohenberger P

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Isolated hepatic perfusion (IHP) of chemotherapy has been proposed to deliver high doses of drug while avoiding systemic toxicity. Hypotonic cisplatin has a high in vitro activity on human colon cancer cells. We studied the safety of a 30-min hypoxic single-pass IHP with hypotonic cisplatin. METHODS:A preli...

journal_title：Annals of surgical oncology

authors： Ortega-Deballon P,Facy O,Consolo D,Magnin G,Tixier H,Simonet M,Rat P,Chauffert B

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The role of surgical resection in patients with large or multinodular hepatocellular carcinoma (HCC) remains unclear. This study evaluated the long-term outcome of patients with hepatic resection for large (>5 cm in diameter) or multinodular (more than three nodules) HCC by using a multi-institutional databa...

journal_title：Annals of surgical oncology

authors： Ng KK,Vauthey JN,Pawlik TM,Lauwers GY,Regimbeau JM,Belghiti J,Ikai I,Yamaoka Y,Curley SA,Nagorney DM,Ng IO,Fan ST,Poon RT,International Cooperative Study Group on Hepatocellular Carcinoma.

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The involvement of lipids in carcinogenic and developmental processes has been reported in some malignancies, but their roles in gastric cancer remain to be analyzed. In this study, we compared the lipid content of gastric cancer tissue and adjacent nonneoplastic mucosa using imaging mass spectrometry. METH...

journal_title：Annals of surgical oncology

authors： Uehara T,Kikuchi H,Miyazaki S,Iino I,Setoguchi T,Hiramatsu Y,Ohta M,Kamiya K,Morita Y,Tanaka H,Baba S,Hayasaka T,Setou M,Konno H

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:We sought to examine how splenectomy as part of up-front cytoreductive surgery in ovarian cancer influences the postoperative course and affects survival. METHODS:We reviewed cases of ovarian cancer diagnosed at Massachusetts General Hospital from 1994 to 2008 and found 44 patients who had a splenectomy as par...

journal_title：Annals of surgical oncology

authors： McCann CK,Growdon WB,Munro EG,Del Carmen MG,Boruta DM,Schorge JO,Goodman A

更新日期：2011-10-01 00:00:00

abstract：:There is increasing evidence regarding extracapsular lymph node involvement (LNI) as a prognostic factor for recurrence and poor prognosis in gastrointestinal malignancies. The aim of this study was to assess the prevalence and prognostic impact of LNI in patients with resected esophageal cancer, comparing adenocarcin...

journal_title：Annals of surgical oncology

authors： Metzger R,Drebber U,Baldus SE,Mönig SP,Hölscher AH,Bollschweiler E

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Adjuvant chemotherapy with 5-fluorouracil modulated by folinic acid, combined with oxaliplatin, has now become an accepted standard of care for patients with stage III colon cancer. In contrast, the use of adjuvant therapy for stage II patients remains controversial, and the identification of reliable progno...

journal_title：Annals of surgical oncology

authors： André T,Sargent D,Tabernero J,O'Connell M,Buyse M,Sobrero A,Misset JL,Boni C,de Gramont A

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Malignant obstruction of the proximal colon (MOPC) traditionally has been treated with acute resection. However, morbidity and mortality rates following these emergency surgeries are high. Initial bowel decompression by stent placement or stoma construction has been used for distal obstructions as an alterna...

journal_title：Annals of surgical oncology

authors： Amelung FJ,Consten ECJ,Siersema PD,Tanis PJ

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The status of the sentinel lymph node is an important predictor for survival in melanoma patients, but it is still unclear if early removal of micrometastases by sentinel lymph node dissection (SLND) alters survival. A large series of melanoma patients from a single center with long-term follow-up was analyz...

journal_title：Annals of surgical oncology

authors： Satzger I,Meier A,Hoy L,Völker B,Kapp A,Hauschild A,Gutzmer R

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Extensive lymph node dissection (LND) is beneficial in primarily resected esophageal cancer patients. Such benefit was believed to be seen in neoadjuvant chemoradiotherapy (CRT)-treated patients, but evidence was inconsistent. We hypothesized that CRT might offset the benefit of LND in certain subgroup of pa...

journal_title：Annals of surgical oncology

authors： Chao YK,Liu HP,Hsieh MJ,Wu YC,Liu YH,Yeh CH,Chang HK,Tseng CK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:CA 19-9 levels are useful for the diagnosis of patients with pancreatic adenocarcinoma. However, interest has recently turned toward its use as a prognostic indicator. The purpose of this study is to determine whether postoperative CA 19-9 levels predict disease-free survival (DFS) and median survival (MS) i...

journal_title：Annals of surgical oncology

authors： Montgomery RC,Hoffman JP,Riley LB,Rogatko A,Ridge JA,Eisenberg BL

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Despite the potential for residual lymph node metastases after a negative or positive sentinel lymph node biopsy (SLNB), breast cancer patients rarely experience regional recurrences (RRs). This study aimed to quantify the effects of nonsurgical treatments on RR incidence among SLNB-negative (SLNB N0) breast...

journal_title：Annals of surgical oncology

authors： van Steenhoven JEC,Kuijer A,van Maaren MC,Roos M,Elias SG,van Diest PJ,Siesling S,Smidt ML,Boersma LJ,van Dalen T

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Experimental studies have revealed that D2-40 is useful in identifying the presence of lymphatic invasion in various malignant neoplasms, but the clinical significance remains unclear. The purpose of this study is to assess the clinical significance of D2-40 status in completely resected non-small cell lung ...

journal_title：Annals of surgical oncology

authors： Iwakiri S,Nagai S,Katakura H,Takenaka K,Date H,Wada H,Tanaka F

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:AT-rich interactive domain 3A (ARID3A) is a member of the ARID family of DNA-binding proteins. Previous reports have shown that ARID3A controls cell growth in a p53-dependent manner. Recently, it has been reported that expression of the ARID3A protein was markedly increased in colon cancer tissue compared wi...

journal_title：Annals of surgical oncology

authors： Song M,Kim H,Kim WK,Hong SP,Lee C,Kim H

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:0.6-12.7% of patients with primary cutaneous melanoma will develop additional melanomas. Pathologic features of tumors in patients with multiple primary cutaneous melanomas have not been well described. In this large, international, multicenter, case-control study, we compared the clinicopathologic features ...

journal_title：Annals of surgical oncology

authors： Murali R,Goumas C,Kricker A,From L,Busam KJ,Begg CB,Dwyer T,Gruber SB,Kanetsky PA,Orlow I,Rosso S,Thomas NE,Berwick M,Scolyer RA,Armstrong BK,GEM Study Group.

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:It is still controversial whether tumor size (Ts) should be considered an important indicator for evaluation the prognosis of gastric cancer (GC). The purpose of this study was to elucidate the prognostic prediction superiority of Ts in the large-scale cohort of GC patients. METHODS:Data from 1,521 patients...

journal_title：Annals of surgical oncology

authors： Deng J,Zhang R,Pan Y,Ding X,Cai M,Liu Y,Liu H,Bao T,Jiao X,Hao X,Liang H

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The interval between preoperative chemoradiotherapy and surgery reportedly affects perioperative outcomes and survival; however, the optimal interval in esophageal cancer patients remains uncertain. OBJECTIVE:Our aim was to determine whether a prolonged interval between preoperative neoadjuvant chemoradioth...

journal_title：Annals of surgical oncology

authors： Wakita A,Motoyama S,Sato Y,Nagaki Y,Fujita H,Terata K,Imai K,Minamiya Y

更新日期：2020-10-13 00:00:00

abstract：INTRODUCTION:Primary pancreatic lymphoma (PPL) is a rare tumor that is often misdiagnosed. Clinicopathologic features, optimal therapy, and outcomes are not well defined. We reviewed our institutional experience with PPL. METHODS:Search of our institutional database identified that between 1987-2012, 21,760 patients w...

journal_title：Annals of surgical oncology

authors： Sadot E,Yahalom J,Do RK,Teruya-Feldstein J,Allen PJ,Gönen M,D'Angelica MI,Kingham TP,Jarnagin WR,DeMatteo RP

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:We have previously reported that older patients with clinical stage I and II primary cutaneous. Melanoma had lower survival rates compared to younger patients. We postulated that the incidence of nodal metastasis would therefore be higher among older melanoma patients. METHODS:The expanded American Joint Commi...

journal_title：Annals of surgical oncology

authors： Balch CM,Thompson JF,Gershenwald JE,Soong SJ,Ding S,McMasters KM,Coit DG,Eggermont AM,Gimotty PA,Johnson TM,Kirkwood JM,Leong SP,Ross MI,Byrd DR,Cochran AJ,Mihm MC Jr,Morton DL,Atkins MB,Flaherty KT,Sondak VK

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Intraperitoneal chemotherapy is used to treat peritoneal surface-spreading malignancies. We sought to determine whether volume and surface area of the intraperitoneal chemotherapy compartments are associated with overall survival and posttreatment glomerular filtration rate (GFR) in malignant peritoneal meso...

journal_title：Annals of surgical oncology

authors： Leinwand JC,Zhao B,Guo X,Krishnamoorthy S,Qi J,Graziano JH,Slavkovic VN,Bates GE,Lewin SN,Allendorf JD,Chabot JA,Schwartz LH,Taub RN

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Breast conservation therapy (BCT) and adjuvant hormonal therapy for estrogen-receptor positive breast cancers have become standard of care. Our objectives were to evaluate trends in the surgical management and adjuvant therapy for early-stage breast cancer and to identify factors predicting survival. METHOD...

journal_title：Annals of surgical oncology

authors： Kennedy T,Stewart AK,Bilimoria KY,Patel-Parekh L,Sener SF,Winchester DP

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Reports show miR-23b to be a cancer-related biomarker in various cancer types. Interestingly, it has a dual role of oncogenic and tumor-suppressive functions, depending on the cancer type. This study focused on the unknown association of miR-23b-3p with hepatocellular carcinoma (HCC). METHODS:Expression of ...

journal_title：Annals of surgical oncology

authors： Hayashi M,Yamada S,Kurimoto K,Tanabe H,Hirabayashi S,Sonohara F,Inokawa Y,Takami H,Kanda M,Tanaka C,Nakayama G,Koike M,Kodera Y

更新日期：2020-11-02 00:00:00

abstract：BACKGROUND:Data on the importance of margin status after total thyroidectomy for papillary thyroid cancer (PTC) remain limited. This study sought to identify factors associated with positive margins and to determine the impact of positive margins on survival for patients with PTC. METHODS:The National Cancer Data Base...

journal_title：Annals of surgical oncology

authors： Youngwirth LM,Adam MA,Scheri RP,Roman SA,Sosa JA

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The role of postmastectomy radiotherapy (PMRT) in breast cancer patients receiving neoadjuvant chemotherapy (NAC) is controversial. We aimed to evaluate the effectiveness of radiotherapy in patients treated with NAC and mastectomy in the Japanese Breast Cancer Registry. METHODS:We enrolled patients who rece...

journal_title：Annals of surgical oncology

authors： Miyashita M,Niikura N,Kumamaru H,Miyata H,Iwamoto T,Kawai M,Anan K,Hayashi N,Aogi K,Ishida T,Masuoka H,Iijima K,Masuda S,Tsugawa K,Kinoshita T,Tsuda H,Nakamura S,Tokuda Y

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To determine survival differences for patients undergoing colonic or rectal resection for cancer on the basis of the specific anatomical location of primary tumor. METHODS:A total of 143,747 patients undergoing segmental colectomy, hemicolectomy, anterior resection, or abdominoperineal resection (APER) for ade...

journal_title：Annals of surgical oncology

authors： Bhangu A,Kiran RP,Slesser A,Fitzgerald JE,Brown G,Tekkis P

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Identification of gastric cancer-related molecules is necessary to elucidate the pathological mechanisms of this heterogeneous disease. The purpose of this study was to identify novel genes associated with aggressive phenotypes of gastric cancer. METHODS:Global expression profiling was conducted using tissu...

journal_title：Annals of surgical oncology

authors： Uno Y,Kanda M,Miwa T,Umeda S,Tanaka H,Tanaka C,Kobayashi D,Suenaga M,Hattori N,Hayashi M,Yamada S,Nakayama G,Fujiwara M,Kodera Y

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Primary extended resection has been proposed as the initial treatment for patients with retroperitoneal sarcoma. This approach comprises an extended en-bloc resection of the directly infiltrated organs and adjacent uninvolved organs. The results of such radical surgery have yet to be validated. This retrospe...

journal_title：Annals of surgical oncology

authors： Pasquali S,Vohra R,Tsimopoulou I,Vijayan D,Gourevitch D,Desai A

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Myxoid liposarcoma (MLS), the second most common subtype of liposarcoma, occurs predominantly in the extremities of young adults and has a disproportionately high tendency to metastasize to unusual soft tissue locations, before disseminated spread or pulmonary metastases. Anecdotal evidence, mainly supported...

journal_title：Annals of surgical oncology

authors： Schwab JH,Boland P,Guo T,Brennan MF,Singer S,Healey JH,Antonescu CR

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Contralateral prophylactic mastectomy (CPM) is expected to add surgical morbidity but this incremental risk has not yet been defined. We sought to quantify the additional risks associated with CPM and determine how these risks influence the time to adjuvant therapy. METHODS:We identified women undergoing ma...

journal_title：Annals of surgical oncology

authors： Eck DL,Perdikis G,Rawal B,Bagaria S,McLaughlin SA

更新日期：2014-10-01 00:00:00