Society of Surgical Oncology 72nd Annual Cancer Symposium.

abstract：BACKGROUND:Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome. Up to 30% of families with HDGC have mutations in the E-cadherin gene, CDH1. The role of prophylactic versus therapeutic gastrectomy for HDGC was studied prospectively. METHODS:Eighteen consecutive patients with CDH1 mutation...

journal_title：Annals of surgical oncology

authors： Chen Y,Kingham K,Ford JM,Rosing J,Van Dam J,Jeffrey RB,Longacre TA,Chun N,Kurian A,Norton JA

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Poly(ADP-ribose) polymerase (PARP) is an important regulator of programmed cell death in response to alkylating agents such as temozolomide (TMZ). The goal of this study was to determine if a systemically administered PARP-inhibitor (INO-1001) could augment the efficacy of TMZ in a rat model of extremity mal...

journal_title：Annals of surgical oncology

authors： Toshimitsu H,Yoshimoto Y,Augustine CK,Padussis JC,Yoo JS,Angelica Selim M,Pruitt SK,Friedman HS,Ali-Osman F,Tyler DS

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The differences between perihilar cholangiocarcinoma (PHCC) and distal cholangiocarcinoma (DCC) regarding recurrence and the factors that affect recurrence after surgery are unclear. This study aims to investigate the differences in recurrence patterns between patients with PHCC and those with DCC after surg...

journal_title：Annals of surgical oncology

authors： Nakanishi Y,Okamura K,Tsuchikawa T,Nakamura T,Noji T,Asano T,Matsui A,Tanaka K,Murakami S,Ebihara Y,Kurashima Y,Narasaki H,Amano T,Shichinohe T,Hirano S

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Robotic surgery is gaining momentum with advantages for minimally invasive management of pancreatic diseases. The objective of this meta-analysis is to compare the clinical and oncologic safety and efficacy of robotic versus open pancreatectomy. METHODS:A systematic review of the literature was performed to...

journal_title：Annals of surgical oncology

authors： Zhang J,Wu WM,You L,Zhao YP

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Neuroendocrine tumors are becoming increasingly prevalent, with many patients presenting with or developing metastatic disease to the liver. METHODS:In this landmark series paper, we highlight the critical studies that have defined the surgical management of neuroendocrine tumor liver metastases, as well as...

journal_title：Annals of surgical oncology

authors： Gangi A,Howe JR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Metastatic breast cancer is an aggressive disease associated with recurrence and decreased survival. To improve outcomes and develop more effective treatment strategies for patients with breast cancer, it is important to understand the molecular mechanisms underlying metastasis. METHODS:We used allelic imba...

journal_title：Annals of surgical oncology

authors： Becker TE,Ellsworth RE,Deyarmin B,Patney HL,Jordan RM,Hooke JA,Shriver CD,Ellsworth DL

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Surgical resection of the primary tumor for patients who present with incurable stage IV colorectal cancer is controversial. National practice patterns have not been described. We evaluated the use of primary tumor resection in patients presenting with stage IV colorectal cancer. METHODS:Patients with stage...

journal_title：Annals of surgical oncology

authors： Cook AD,Single R,McCahill LE

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:We sought to identify genes associated with the progression and metastasis of esophageal squamous-cell cancer by comparing the expression profiles of normal, primary cancer, and metastatic cancer cells isolated with laser microdissection. METHODS:Oligo microarray analysis identified several lymph node-speci...

journal_title：Annals of surgical oncology

authors： Kita Y,Mimori K,Iwatsuki M,Yokobori T,Ieta K,Tanaka F,Ishii H,Okumura H,Natsugoe S,Mori M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:COX inhibitors and beta-blockers were recently suggested to reduce cancer progression through inhibition of tumor proliferation and growth factor secretion, induction of tumor apoptosis, and prevention of cellular immune suppression during the critical perioperative period. Here we evaluated the perioperativ...

journal_title：Annals of surgical oncology

authors： Benish M,Bartal I,Goldfarb Y,Levi B,Avraham R,Raz A,Ben-Eliyahu S

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Because fine-needle aspiration cannot reliably discriminate between benign and malignant follicular thyroid lesions, some surgeons use intraoperative frozen section (FS) to guide operative management. To determine the utility of FS for these lesions, we reviewed our institutional experience. METHODS:Between...

journal_title：Annals of surgical oncology

authors： Callcut RA,Selvaggi SM,Mack E,Ozgul O,Warner T,Chen H

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Resection has been the standard of care for patients with solitary hepatocellular carcinoma (HCC). Transarterial embolization and percutaneous ablation are alternative therapies often reserved for suboptimal surgical candidates. Here we compare long-term outcomes of patients with solitary HCC treated with re...

journal_title：Annals of surgical oncology

authors： Elnekave E,Erinjeri JP,Brown KT,Thornton RH,Petre EN,Maybody M,Maluccio MA,Hsu M,Sofocleous CT,Getrajdman GI,Brody LA,Solomon SB,Alago W,Fong Y,Jarnagin WR,Covey AM

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:The efficacy of chemoprevention for breast cancer risk reduction has been demonstrated in randomized controlled trials; however, use remains low. We sought to determine whether uptake differed by risk factors, and to identify reasons for refusal and termination. METHODS:Women seen in a high-risk c...

journal_title：Annals of surgical oncology

authors： Flanagan MR,Zabor EC,Stempel M,Mangino DA,Morrow M,Pilewskie ML

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The aim of this retrospective analysis was to analyze the results of treatment of patients with cervical node metastases from carcinoma of occult primary with a policy including neck dissection and postoperative comprehensive radiotherapy. METHODS:Ninety patients were treated with curative intent from 1990 ...

journal_title：Annals of surgical oncology

authors： Boscolo-Rizzo P,Gava A,Da Mosto MC

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The patients with early gastric cancer who have undergone incomplete endoscopic resection (ER) generally need additional surgery because of the possibility of lymph node metastasis. The aim of study was to evaluate the optimal time interval from ER to additive surgery by evaluating the effect of time interva...

journal_title：Annals of surgical oncology

authors： Kim MJ,Kim JH,Lee YC,Kim JW,Choi SH,Hyung WJ,Noh SH,Youn YH,Park H,Lee SI

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Plantar melanomas are a challenge to reconstruct after wide excision. Non-glaborous skin grafts have resulted in tissue loss, hyperkeratosis, marginal scarring, and poor functional outcomes, leading many to utilize various flaps for reconstruction that are technically demanding and associated with increase...

journal_title：Annals of surgical oncology

authors： Maker AV,Iteld L

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Limited data exist that describe the long-term outcomes from additional surgery following non-curative endoscopic resection (ER) of early gastric cancer (EGC) in older people. This study aimed to determine the appropriate treatment strategy for these patients. METHODS:We analyzed data from 2895 patients who...

journal_title：Annals of surgical oncology

authors： Pyo JH,Lee H,Min BH,Lee JH,Kim KM,Yoo H,Ahn S,An JY,Choi MG,Lee JH,Sohn TS,Bae JM,Kim JJ,Kim S

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Heated intraoperative intraperitoneal chemotherapy achieves high peritoneal concentrations with limited systemic absorption and has become an important tool in the management of patients with peritoneal carcinomatosis from low-grade malignancies such as pseudomyxoma peritonei and in selected cases of high-gr...

journal_title：Annals of surgical oncology

authors： Esquivel J,Angulo F,Bland RK,Stephens AD,Sugarbaker PH

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:Neuropathic pain (NPP) following breast surgery extends morbidity in the postoperative period. The incidence and etiology of postoperative NPP remains unclear and under-reported in literature. This study aims to define the incidence of neuropathic pain following breast surgery and to identify patient characteri...

journal_title：Annals of surgical oncology

authors： Wilson GC,Quillin RC 3rd,Hanseman DJ,Lewis JD,Edwards MJ,Shaughnessy EA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to analyze the outcome of patients that received neoadjuvant chemotherapy prior to resection for colorectal liver metastases (CRLM) and compare them with a matched cohort of patients that underwent resection followed by adjuvant chemotherapy. METHODS:687 patients have undergone cur...

journal_title：Annals of surgical oncology

authors： Malik HZ,Farid S,Al-Mukthar A,Anthoney A,Toogood GJ,Lodge JP,Prasad KR

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Identification of melanoma patients who need completion lymphadenectomy and adjuvant treatment after positive sentinel lymph node (SLN) biopsy would be a fundamental step forward toward personalized medicine. This study tested the hypothesis that the microscopic features of metastatic SLNs might predict not ...

journal_title：Annals of surgical oncology

authors： Rossi CR,De Salvo GL,Bonandini E,Mocellin S,Foletto M,Pasquali S,Pilati P,Lise M,Nitti D,Rizzo E,Montesco MC

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:The purpose of the current study was to conduct a patient-centered investigation of reconstruction practices following mastectomy at our institution. METHODS:A questionnaire was administered to patients who underwent unilateral or bilateral mastectomy for breast cancer from 2006 to 2010. The survey queried ...

journal_title：Annals of surgical oncology

authors： Elmore L,Myckatyn TM,Gao F,Fisher CS,Atkins J,Martin-Dunlap TM,Margenthaler JA

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The benefit of completion lymph node dissection (CLND) in melanoma patients with a positive sentinel lymph node (SLN) remains unknown. METHODS:We identified patients with a positive SLN from 1994 to 2012. Patient and tumor characteristics, reasons for not undergoing CLND, patterns of recurrence, and melanom...

journal_title：Annals of surgical oncology

authors： Bamboat ZM,Konstantinidis IT,Kuk D,Ariyan CE,Brady MS,Coit DG

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:As tumor burden increases in colorectal cancer, treatment complexity progresses from colectomy to hepatectomy and lastly to cytoreductive surgery with heated intraperitoneal chemotherapy (CRS-HIPEC). The aim of this study was to evaluate whether disparities exist in the access to progressively more complex s...

journal_title：Annals of surgical oncology

authors： Tabrizian P,Overbey J,Carrasco-Avino G,Bagiella E,Labow DM,Sarpel U

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:While previously thought to be clinically indolent, recent data suggest significant late metastatic capacity of solitary fibrous tumors (SFTs). We define prognostic factors for recurrence and disease-specific death (DSD) in resected primary SFTs. METHODS:Resected primary SFTs from 1982 to 2015 were identified ...

journal_title：Annals of surgical oncology

authors： Gholami S,Cassidy MR,Kirane A,Kuk D,Zanchelli B,Antonescu CR,Singer S,Brennan M

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Preliminary data indicate that tyrosine kinase inhibitors (TKIs) function through rearranged during transfection (RET) in breast cancer. However, TKIs are not specific and can block several receptor tyrosine kinases (RTKs). This study used cell lines and primary breast cancer specimens to determine factors a...

journal_title：Annals of surgical oncology

authors： Spanheimer PM,Lorenzen AW,De Andrade JP,Kulak MV,Carr JC,Woodfield GW,Sugg SL,Weigel RJ

更新日期：2015-12-01 00:00:00

abstract：:The number of early gastric cancer (EGC) cases has been increasing because of improved diagnostic procedures. Applications of function-preserving gastric cancer surgery may therefore also be increasing because of its low incidence of lymph node metastasis, excellent survival rates, and the possibility of less-invasive...

journal_title：Annals of surgical oncology

authors： Hiki N,Nunobe S,Kubota T,Jiang X

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The strategy of radical surgery for stage 2 endometrial cancer (EC) remains controversial. This meta-analysis aimed to investigate the impact of radical hysterectomy (RH) versus simple hysterectomy (SH) on survival of patients with stage 2 EC. METHODS:A systematic review was conducted to identify studies co...

journal_title：Annals of surgical oncology

authors： Liu T,Tu H,Li Y,Liu Z,Liu G,Gu H

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The aim of this retrospective study was to investigate the incidence of mesenteric lymph node (MLN) involvement, and its prognostic role in advanced ovarian cancer (OC). METHODS:OC patients undergoing rectosigmoid resection during primary debulking surgery or interval debulking surgery were recorded. Progre...

journal_title：Annals of surgical oncology

authors： Gallotta V,Fanfani F,Fagotti A,Chiantera V,Legge F,Gueli Alletti S,Nero C,Margariti AP,Papa V,Alfieri S,Ciccarone F,Scambia G,Ferrandina G

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Cytoreductive surgery and heated intraperitoneal chemotherapy (CS/HIPEC) is performed for selected indications at a limited number of specialized centers worldwide. Currently there is no standardized approach to the perioperative care process. We sought to capture current practices in the perioperative manag...

journal_title：Annals of surgical oncology

authors： Maciver AH,Al-Sukhni E,Esquivel J,Skitzki JJ,Kane JM 3rd,Francescutti VA

更新日期：2017-04-01 00:00:00

abstract：:Multiple randomized trials, as well as a meta-analysis of these studies, have confirmed the equivalence of breast-conservation and mastectomy. In addition, in unselected populations, adjuvant radiation therapy following lumpectomy has been shown to decrease in-breast recurrence and improve overall survival. However, r...

journal_title：Annals of surgical oncology

authors： Bellon JR,Golshan M,Solin LJ

更新日期：2015-10-01 00:00:00