Escalation of socioeconomic disparities among patients with colorectal cancer receiving advanced surgical treatment.

Abstract:

BACKGROUND:As tumor burden increases in colorectal cancer, treatment complexity progresses from colectomy to hepatectomy and lastly to cytoreductive surgery with heated intraperitoneal chemotherapy (CRS-HIPEC). The aim of this study was to evaluate whether disparities exist in the access to progressively more complex surgical treatment options. METHODS:Patients undergoing surgery for colorectal cancer were grouped by treatment type: group 1 (n = 224) underwent colectomy for nonmetastatic disease, group 2 (n = 112) underwent hepatectomy for liver metastasis, and group 3 (n = 112) underwent CRS-HIPEC for carcinomatosis. RESULTS:Whites were predominant in the HIPEC group (71.4 %) compared to the hepatectomy (67.9 %) and colectomy (57.6 %) groups (p = 0.025). The majority of the privately insured patients were in the HIPEC group (70.5 %) compared to the hepatectomy (56.2 %) and colectomy (30.4 %) groups (p < 0.0001). Distance traveled to the hospital was farthest on average in the HIPEC group (104.6 ± 258.3 km) compared to the hepatectomy (29.0 ± 28.0 km) or colectomy (26.4  ± 66.2 km) group (p < 0.0001). Mean household income also varied between the three groups, with HIPEC patients earning $56,957 (±24,124), hepatectomy patients earning $56,999 (±28,588), and colectomy patients earning ($51,518 ± 24,201) (p = 0.0503) on average per year. The HIPEC cohort contained a higher proportion of English speakers (90.2 %) than the other groups (hepatectomy 87.9 %, colectomy 85.3 %); however, this difference was not statistically significant (p = 0.43). CONCLUSIONS:CRS-HIPEC is not accessed equally across all socioeconomic groups. Patients undergoing HIPEC were most often white, English speaking, and privately insured; had a higher mean income; and had traveled the greatest distances on average to access surgical care.

journal_name

Ann Surg Oncol

authors

Tabrizian P,Overbey J,Carrasco-Avino G,Bagiella E,Labow DM,Sarpel U

doi

10.1245/s10434-014-4220-6

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

1746-50

issue

5

eissn

1068-9265

issn

1534-4681

journal_volume

22

pub_type

杂志文章
  • The 1999 James Ewing Lecture: in pursuit of molecules of oncogenesis and neoplastic therapy.

    abstract::Breast cancer is a progressive, phenotypic, genetic and epigenetic alteration, induced by various stimulants of which the principal steroid hormone, estrogen, initiates and promotes neoplastic transformation of normal ductal mammary epithelium to acquire distinct biochemical and molecular characteristics. The molecula...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s10434-999-0528-z

    authors: Bland KI

    更新日期:1999-09-01 00:00:00

  • Hilar cholangiocarcinoma: a review and commentary.

    abstract::Hilar cholangiocarcinoma is an uncommon cause of malignant biliary obstruction marked by local tumor spread for which surgery offers the only chance of cure. The diagnostic evaluation and surgical management of this disease continues to evolve. Although direct cholangiography and endoscopic biliary procedures have bee...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1007/s10434-000-0055-4

    authors: Chamberlain RS,Blumgart LH

    更新日期:2000-01-01 00:00:00

  • Pilot Study of a New Nonradioactive Surgical Guidance Technology for Locating Nonpalpable Breast Lesions.

    abstract:BACKGROUND:The current technique for locating nonpalpable breast lesions is wire localization (WL). Radioactive seed localization and intraoperative ultrasound were developed to improve difficulties with WL. The SAVI SCOUT surgical guidance system was developed to improve these methods. The SCOUT system is a non-radioa...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-5079-x

    authors: Cox CE,Garcia-Henriquez N,Glancy MJ,Whitworth P,Cox JM,Themar-Geck M,Prati R,Jung M,Russell S,Appleton K,King J,Shivers SC

    更新日期:2016-06-01 00:00:00

  • ROS1 receptor tyrosine kinase, a druggable target, is frequently overexpressed in non-small cell lung carcinomas via genetic and epigenetic mechanisms.

    abstract:BACKGROUND:Microarray analyses have revealed significantly elevated expression of the proto-oncogene ROS1 receptor tyrosine kinase in 20-30% of non-small cell lung carcinomas (NSCLC). Selective and potent ROS1 kinase inhibitors have recently been developed and oncogenic rearrangement of ROS1 in NSCLC identified. METHO...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-012-2553-6

    authors: Lee HJ,Seol HS,Kim JY,Chun SM,Suh YA,Park YS,Kim SW,Choi CM,Park SI,Kim DK,Kim YH,Jang SJ

    更新日期:2013-01-01 00:00:00

  • Management of Neuroendocrine Tumor Liver Metastases: Long-Term Outcomes and Prognostic Factors from a Large Prospective Database.

    abstract:BACKGROUND:Liver-directed therapies have been used to treat neuroendocrine liver metastases (NELM) for both symptomatic improvement and tumor growth control. We reviewed our experience with NELM to investigate the outcomes of available treatment modalities and to identify prognostic factors for survival. METHODS:We id...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-017-5839-x

    authors: Fairweather M,Swanson R,Wang J,Brais LK,Dutton T,Kulke MH,Clancy TE

    更新日期:2017-08-01 00:00:00

  • Stage-specific effect of adjuvant therapy following gastric cancer resection: a population-based analysis of 4,041 patients.

    abstract:BACKGROUND:Adjuvant chemoradiotherapy improved survival in patients with resected gastric adenocarcinoma in the Southwest Oncology Group/Intergroup 0116 trial. Our objective was to examine the impact of adjuvant treatment on overall survival (OS) in the general population. METHODS:Patients 18-85 years old who had unde...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-007-9640-0

    authors: Coburn NG,Govindarajan A,Law CH,Guller U,Kiss A,Ringash J,Swallow CJ,Baxter NN

    更新日期:2008-02-01 00:00:00

  • The Landmark Series: Randomized Trials Examining Surgical Margins for Cutaneous Melanoma.

    abstract::Between 1980 and 2004, six randomized, controlled trials (RCTs) have been performed to evaluate the width of surgical margin excision for primary cutaneous melanoma and its influence on recurrence and survival. These trials have led to the current recommendation of not more than a 2-cm margin excision and have allowed...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1245/s10434-019-07866-y

    authors: Angeles CV,Wong SL,Karakousis G

    更新日期:2020-01-01 00:00:00

  • Feasibility of a novel approach to inguinal lymphadenectomy: minimally invasive groin dissection for melanoma.

    abstract:INTRODUCTION:Inguinal lymphadenectomy for metastatic melanoma is reported to have a complication rate as high as 50%. Wound dehiscence has been reported to occur in more than half of these patients, and as a result many surgeons routinely use sartorius muscle transposition to protect against the potential for exposed v...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-009-0816-7

    authors: Delman KA,Kooby DA,Ogan K,Hsiao W,Master V

    更新日期:2010-03-01 00:00:00

  • Correction to: Clinical Surveillance After Macroscopically Complete Surgery for Low-Grade Appendiceal Mucinous Neoplasms (LAMN) with or Without Limited Peritoneal Spread: Long-Term Results in a Prospective Series.

    abstract::In the original article Massimo Milione's last name was spelled incorrectly. It is correct as reflected here. The original article has also been updated. ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,已发布勘误

    doi:10.1245/s10434-018-6341-9

    authors: Guaglio M,Sinukumar S,Kusamura S,Milione M,Pietrantonio F,Battaglia L,Guadagni S,Baratti D,Deraco M

    更新日期:2018-12-01 00:00:00

  • Surgical resection of primary tumors in patients who present with stage IV colorectal cancer: an analysis of surveillance, epidemiology, and end results data, 1988 to 2000.

    abstract:BACKGROUND:Surgical resection of the primary tumor for patients who present with incurable stage IV colorectal cancer is controversial. National practice patterns have not been described. We evaluated the use of primary tumor resection in patients presenting with stage IV colorectal cancer. METHODS:Patients with stage...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/ASO.2005.06.012

    authors: Cook AD,Single R,McCahill LE

    更新日期:2005-08-01 00:00:00

  • Long-term outcomes in patients with calciphylaxis from hyperparathyroidism.

    abstract:BACKGROUND:Calciphylaxis is a rare condition associated with chronic renal failure and entails a very poor prognosis. Pathogenesis is poorly understood but involves abnormalities in calcium and phosphorus metabolism that lead to vascular and extravascular calcification. Patients present with painful ulcerating plaques ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/ASO.2006.03.042

    authors: Duffy A,Schurr M,Warner T,Chen H

    更新日期:2006-01-01 00:00:00

  • Implementing the Prospective Surveillance Model (PSM) of Rehabilitation for Breast Cancer Patients with 1-Year Postoperative Follow-up, a Prospective, Observational Study.

    abstract:BACKGROUND:The Prospective Surveillance Model (PSM) of rehabilitation for patients with breast cancer aims for early identification, treatment, and support of physical impairments postoperatively. The purpose of this study was to describe the incidence of impairments during the first postoperative year and the differen...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-016-5315-z

    authors: Lai L,Binkley J,Jones V,Kirkpatrick S,Furbish C,Stratford P,Thompson W,Sidhu A,Farley C,Okoli J,Beech D,Gabram S

    更新日期:2016-10-01 00:00:00

  • Natural History of Gastric Cancer: Observational Study of Gastric Cancer Patients Not Treated During Follow-Up.

    abstract:BACKGROUND:Understanding the natural progression of untreated gastric cancer is critical for determining the disease prognosis as well as treatment options and timing. The aim of this study is to analyze the natural history of gastric cancer. PATIENTS AND METHODS:We included patients with gastric cancer who had not re...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-07455-z

    authors: Oh SY,Lee JH,Lee HJ,Kim TH,Huh YJ,Ahn HS,Suh YS,Kong SH,Kim GH,Ahn SJ,Kim SH,Choi Y,Yang HK

    更新日期:2019-09-01 00:00:00

  • ASO Author Reflections: Health Disparities in Pancreatic Cancer.

    abstract:: ...

    journal_title:Annals of surgical oncology

    pub_type: 评论,杂志文章

    doi:10.1245/s10434-018-6961-0

    authors: Lutfi W,Hogg ME

    更新日期:2018-12-01 00:00:00

  • A phase I study of hyperthermic isolated hepatic perfusion with oxaliplatin in the treatment of unresectable liver metastases from colorectal cancer.

    abstract::Isolated hepatic perfusion (IHP) is a proven approach for regional delivery of chemotherapy in patients with unresectable primary and metastatic tumors of the liver. Most trials of IHP have utilized melphalan as the active drug in the perfusate. We performed a phase I trial to evaluate the efficacy, safety, and maximu...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0179-5

    authors: Zeh HJ 3rd,Brown CK,Holtzman MP,Egorin MJ,Holleran JL,Potter DM,Bartlett DL

    更新日期:2009-02-01 00:00:00

  • A comparison of clinical and pathologic assessments for the prediction of occult nipple involvement in nipple-sparing mastectomies.

    abstract:BACKGROUND:Nipple-sparing mastectomy (NSM) for both risk reduction and cancer is increasing. In the cancer setting, most studies suggest the use of both clinical and intraoperative biopsy criteria in patient selection. This study examines the use of both biopsy and clinical criteria in women undergoing total nipple-rem...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-012-2511-3

    authors: Stolier A,Stone JC,Moroz K,Hanemann CW,McNabb L,Jones SD,Lacey M

    更新日期:2013-01-01 00:00:00

  • An aggressive approach to extrahepatic cholangiocarcinomas is warranted: margin status does not impact survival after resection.

    abstract:BACKGROUND:With cholangiocarcinoma, the only hope of a cure is resection. This study was undertaken to determine the impact of margin status, stage, tumor location, and adjuvant therapy on survival after resection of extrahepatic cholangiocarcinoma. METHODS:From 1985-2006, 91 patients underwent resections of cholangio...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-007-9756-2

    authors: Hernandez J,Cowgill SM,Al-Saadi S,Villadolid D,Ross S,Kraemer E,Shapiro M,Mullinax J,Cooper J,Goldin S,Zervos E,Rosemurgy A

    更新日期:2008-03-01 00:00:00

  • Use of the Nerve Integrity Monitor during Thyroid Surgery Aids Identification of the External Branch of the Superior Laryngeal Nerve.

    abstract:BACKGROUND:The external branch of the superior laryngeal nerve (EBSLN) is at risk during thyroid surgery. Despite meticulous dissection and visualization, the EBSLN can be mistaken for other structures. The nerve integrity monitor (NIM) allows EBSLN confirmation with cricothyroid twitch on stimulation. AIMS:The aim of...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-4142-3

    authors: Glover AR,Norlén O,Gundara JS,Morris M,Sidhu SB

    更新日期:2015-01-01 00:00:00

  • Total Laparoscopic Pancreaticoduodenectomy with Venous Reconstruction for Pancreatic Head Cancer with Involvement of the Superior Mesenteric Vein-Portal Vein Confluence.

    abstract:BACKGROUND:Laparoscopic pancreaticoduodenectomy with venous reconstruction is not commonly performed due to its technical challenges. In this video, we focus on the technical aspects for how to perform this procedure safely. METHODS:In a 69-year-old female with jaundice and diarrhea, a computed tomography scan showed ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-018-6762-5

    authors: Garbarino GM,Fuks D,Cowan J,Ward M,Moisan F,Donatelli G,Beaussier M,Gayet B

    更新日期:2018-12-01 00:00:00

  • High RAD18 Expression is Associated with Disease Progression and Poor Prognosis in Patients with Gastric Cancer.

    abstract:BACKGROUND:RAD18 plays an important role in DNA damage repair by inducing monoubiquitinated PCNA (mUB-PCNA) in both cancer and normal tissues. Previous studies have not determined the significance of RAD18 expression in clinical gastric cancer (GC) samples. Thus, this study aimed to clarify the expression and functiona...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-08518-2

    authors: Baatar S,Bai T,Yokobori T,Gombodorj N,Nakazawa N,Ubukata Y,Kimura A,Kogure N,Sano A,Sohda M,Sakai M,Tumenjargal A,Ogata K,Kuwano H,Shirabe K,Saeki H

    更新日期:2020-10-01 00:00:00

  • Serious Postoperative Complications Affect Early Recurrence After Cytoreductive Surgery and HIPEC for Colorectal Peritoneal Carcinomatosis.

    abstract:BACKGROUND:The prognosis of patients with peritoneally metastasized colorectal cancer has improved significantly with the introduction of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (CRS + HIPEC). Although a macroscopically complete resection is achieved in nearly every patient, recurren...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-4297-y

    authors: Simkens GA,van Oudheusden TR,Luyer MD,Nienhuijs SW,Nieuwenhuijzen GA,Rutten HJ,de Hingh IH

    更新日期:2015-08-01 00:00:00

  • Prognostic value of cytokeratin-positive bone marrow cells of gastric cancer patients.

    abstract:BACKGROUND:Epithelial cells in the bone marrow of patients with gastric cancer suggest tumor dissemination; however, their prognostic implications are controversial. We prospectively evaluated the correlation of bone marrow findings, recurrence rate, and disease-free survival after long-term follow-up. METHODS:Bone ma...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-006-9039-3

    authors: Gretschel S,Schick C,Schneider U,Estevez-Schwarz L,Bembenek A,Schlag PM

    更新日期:2007-02-01 00:00:00

  • Human acellular dermis seeded with autologous fibroblasts enhances bronchial anastomotic healing in an irradiated rodent sleeve resection model.

    abstract:BACKGROUND:The combination of neoadjuvant radiochemotherapy and parenchyma-preserving sleeve resection for lung cancer remains controversial because of potentially increased rate of anastomotic breakdown. We analyzed the effects of applying a decellularized human dermis transplant seeded with autologous fibroblasts in ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-3209-x

    authors: Roessner E,Vitacolonna M,Schulmeister A,Pilz L,Tsagogiorgas C,Brockmann M,Hohenberger P

    更新日期:2013-12-01 00:00:00

  • Age as a prognostic factor in patients with localized melanoma and regional metastases.

    abstract:BACKGROUND:We postulated that the worse prognosis of melanoma with advancing age reflected more aggressive tumor biology and that in younger patients the prognosis would be more favorable. MATERIALS AND METHODS:The expanded AJCC melanoma staging database contained 11,088 patients with complete data for analysis, inclu...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1245/s10434-013-3100-9

    authors: Balch CM,Soong SJ,Gershenwald JE,Thompson JF,Coit DG,Atkins MB,Ding S,Cochran AJ,Eggermont AM,Flaherty KT,Gimotty PA,Johnson TM,Kirkwood JM,Leong SP,McMasters KM,Mihm MC Jr,Morton DL,Ross MI,Sondak VK

    更新日期:2013-11-01 00:00:00

  • Surgical indication for non-curative endoscopic resection in early gastric cancer.

    abstract:BACKGROUND:Endoscopic resection (ER) is an effective treatment for early gastric cancer (EGC) without lymph node metastasis. However, after ER additional surgery may be needed to manage the risks presented by residual cancer or lymph node metastasis. METHODS:ER was performed on 344 gastric adenocarcinomas between Nove...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-007-9536-z

    authors: Ryu KW,Choi IJ,Doh YW,Kook MC,Kim CG,Park HJ,Lee JH,Lee JS,Lee JY,Kim YW,Bae JM

    更新日期:2007-12-01 00:00:00

  • Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer.

    abstract:BACKGROUND:The FAK gene encodes a 125-kDa tyrosine kinase (p125FAK) involved in signal transduction pathways used in cell adhesion, motility, and anchorage-independent growth. Because thyroid carcinomas have a wide variability in their propensity for invasion and metastasis, we studied the expression of FAK in a variet...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02409059

    authors: Owens LV,Xu L,Dent GA,Yang X,Sturge GC,Craven RJ,Cance WG

    更新日期:1996-01-01 00:00:00

  • Survival after resection of multiple hepatic colorectal metastases.

    abstract:BACKGROUND:Hepatic resection is potentially curative in selected patients with colorectal metastases. It is a widely held practice that multiple colorectal hepatic metastases are not resected, although outcome after removal of four or more metastases is not well defined. METHODS:Patients with four or more colorectal h...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/s10434-000-0643-3

    authors: Weber SM,Jarnagin WR,DeMatteo RP,Blumgart LH,Fong Y

    更新日期:2000-10-01 00:00:00

  • Morbidity associated with colostomy reversal after cytoreductive surgery and HIPEC.

    abstract:BACKGROUND:Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has improved the survival in selected colorectal cancer patients with peritoneal metastases. In these patients, the risk of a low anastomosis is sometimes diminished through the creation of a colostomy. Currently, the morbidity...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-3370-2

    authors: de Cuba EM,Verwaal VJ,de Hingh IH,van Mens LJ,Nienhuijs SW,Aalbers AG,Bonjer HJ,te Velde EA

    更新日期:2014-03-01 00:00:00

  • Prediction of response and prognosis by a score including only pretherapeutic parameters in 410 neoadjuvant treated gastric cancer patients.

    abstract:BACKGROUND:Response to neoadjuvant chemotherapy is an independent prognostic factor in locally advanced gastric cancer. However, no prospectively tested pretherapeutic parameters predicting response and/or survival in gastric cancer are available in clinical routine. METHODS:We evaluated the prognostic significance of...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-012-2254-1

    authors: Lorenzen S,Blank S,Lordick F,Siewert JR,Ott K

    更新日期:2012-07-01 00:00:00

  • The utility of intraoperative evaluation of sentinel lymph nodes in breast cancer.

    abstract:BACKGROUND:In breast cancer treatment, intraoperative sentinel lymph node (SLN) evaluation is used to identify patients who may potentially benefit from immediate completion of axillary lymph node dissection. METHODS:Prospectively collected breast cancer registry data identified 516 SLN biopsies between January 2003 a...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-006-9270-y

    authors: Pugliese MS,Tickman R,Wang NP,Atwood M,Beatty JD

    更新日期:2007-03-01 00:00:00