Regional chemotherapy for colorectal hepatic metastases: evidence for improved survival with new drug combinations.

abstract：BACKGROUND:Tumor-associated glycoprotein-72 (TAG-72) is a mucin-like high-molecular-weight glycosylated protein complex overexpressed by many adenocarcinomas. Antigen-directed cancer surgery using radiolabeled anti-TAG-72 murine monoclonal antibodies (muMAbs) has been previously investigated for colorectal cancer. Surv...

journal_title：Annals of surgical oncology

authors： Povoski SP,Hatzaras IS,Mojzisik CM,Arnold MW,Hinkle GH,Hitchcock CL,Young DC,Martin EW Jr

更新日期：2012-01-01 00:00:00

abstract：:Over a decade since the discovery of EGFR mutation, and 6 years since prospective clinical trial data proved that routine molecular pathology tests improve survival in stage IV lung cancer, there is still debate whether to test patients with earlier stages of disease (stage I-III). As discoveries of targeted drugs for...

journal_title：Annals of surgical oncology

authors： Azzoli CG

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Hepatic resection is potentially curative in selected patients with colorectal metastases. It is a widely held practice that multiple colorectal hepatic metastases are not resected, although outcome after removal of four or more metastases is not well defined. METHODS:Patients with four or more colorectal h...

journal_title：Annals of surgical oncology

authors： Weber SM,Jarnagin WR,DeMatteo RP,Blumgart LH,Fong Y

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Achieving an undetectable serum thyroglobulin (Tg) level (<1.0 ng/mL) after surgical and radioiodine treatment for papillary thyroid cancer (PTC) is associated with low recurrence rates and has been termed biochemical remission. This study aimed to determine the effectiveness of total thyroidectomy with ther...

journal_title：Annals of surgical oncology

authors： Hughes DT,Miller BS,Cohen MS,Doherty GM,Gauger PG

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Traditional teaching maintains that patients with primary colorectal adenocarcinoma require timely resection to prevent bleeding, perforation, or obstruction. The true benefits of primary tumor resection remain undocumented for patients presenting with metastatic disease, however. We postulated that resectio...

journal_title：Annals of surgical oncology

authors： Scoggins CR,Meszoely IM,Blanke CD,Beauchamp RD,Leach SD

更新日期：1999-10-01 00:00:00

abstract：PURPOSE:Intraoperative margin assessment can reduce positive margins in patients undergoing breast-conserving surgery. However, reports on intraoperative margin assessment have described only the use of either imprint cytology or frozen section. This study was designed to elucidate the effect of intraoperative margin a...

journal_title：Annals of surgical oncology

authors： Tamanuki T,Namura M,Aoyagi T,Shimizu S,Suwa T,Matsuzaki H

更新日期：2020-08-19 00:00:00

abstract：BACKGROUND:Although esophagectomy traditionally is recommended to perform within 8 weeks after neoadjuvant chemoradiotherapy (nCRT), data from neoadjuvantly treated rectal cancer patients demonstrate that delayed surgery ([8 weeks) can maximize the effect of CRT. Despite these promising data, investigators are concerne...

journal_title：Annals of surgical oncology

authors： Chiu CH,Chao YK,Chang HK,Tseng CK,Chan SC,Liu YH,Chen WH

更新日期：2013-12-01 00:00:00

abstract：INTRODUCTION:Regional lymph node metastasis is an important prognostic factor for patients with gastric cancer. Occult tumour cells (OTCs), including either micrometastases (MMs) or isolated tumour cells (ITCs), may be a key factor in the development of cancer recurrence in pN0 patients. AIMS:We aimed to determine the...

journal_title：Annals of surgical oncology

authors： Tavares A,Wen X,Maciel J,Carneiro F,Dinis-Ribeiro M

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The relative effects of growth hormone on tumor versus host growth and protein metabolism are not known. This study examines the influence of recombinant rat growth hormone (r-rGH) on host and tumor growth, host body composition, and protein synthesis of tumor and host in tumor-bearing rats. METHODS:After l...

journal_title：Annals of surgical oncology

authors： Wolf RF,Ng B,Weksler B,Burt M,Brennan MF

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Effective therapeutic combinations targeting the oncogenic pathway still are unknown in human hepatocellular carcinoma (HCC). The authors previously identified aberrant expression of aurora B kinase as the independent predictor for the lethal recurrence of HCC, showing that AZD1152 induced in vitro and in vi...

journal_title：Annals of surgical oncology

authors： Matsunaga H,Tanaka S,Aihara A,Ogawa K,Matsumura S,Ban D,Ochiai T,Irie T,Kudo A,Nakamura N,Arii S,Tanabe M

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Not all patients respond equally to neoadjuvant chemoradiotherapy (nCRT), with subsequent effects on survival. The systemic inflammatory response has been shown to predict long-term outcomes in colorectal cancer. The current study examined the association between systemic inflammation and nCRT in patients wi...

journal_title：Annals of surgical oncology

authors： Dreyer SB,Powell AG,McSorley ST,Waterston A,Going JJ,Edwards J,McMillan DC,Horgan PG

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:More than 20% of patients undergoing initial breast-conserving surgery (BCS) for cancer require reoperation. To address this concern, the American Society of Breast Surgeons (ASBrS) endorsed 10 processes of care (tools) in 2015 to be considered by surgeons to de-escalate reoperations. In a planned follow-up,...

journal_title：Annals of surgical oncology

authors： Landercasper J,Borgert AJ,Fayanju OM,Cody H 3rd,Feldman S,Greenberg C,Linebarger J,Pockaj B,Wilke L

更新日期：2019-10-01 00:00:00

abstract：:The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of colorectal cancer specifically as it relates to the management of peritoneal surface malignancy. These guidelines are developed with input from leading experts including surgical oncologists, medical oncologists, patho...

journal_title：Annals of surgical oncology

authors： Chicago Consensus Working Group.

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:With cholangiocarcinoma, the only hope of a cure is resection. This study was undertaken to determine the impact of margin status, stage, tumor location, and adjuvant therapy on survival after resection of extrahepatic cholangiocarcinoma. METHODS:From 1985-2006, 91 patients underwent resections of cholangio...

journal_title：Annals of surgical oncology

authors： Hernandez J,Cowgill SM,Al-Saadi S,Villadolid D,Ross S,Kraemer E,Shapiro M,Mullinax J,Cooper J,Goldin S,Zervos E,Rosemurgy A

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:High-grade (HG) mucinous appendiceal neoplasms (MAN) have a worse prognosis than low-grade histology. Our objective was to assess the safety and efficacy of cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) in patients with high-grade, high-volume (HG-HV) peritoneal metastase...

journal_title：Annals of surgical oncology

authors： Polanco PM,Ding Y,Knox JM,Ramalingam L,Jones H,Hogg ME,Zureikat AH,Holtzman MP,Pingpank J,Ahrendt S,Zeh HJ,Bartlett DL,Choudry HA

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The value of adjuvant therapy for esophageal squamous cell carcinoma (ESCC) has been controversial, at least partially due to the lack of efficient criteria for selecting suitable patients. This study aimed to explore the existence of parameters related to lymph node (LN) status that can predict the value of...

journal_title：Annals of surgical oncology

authors： Li Y,Zhao W,Ni J,Zou L,Yang X,Yu W,Fu X,Zhao K,Zhang Y,Chen H,Xiang J,Xie C,Zhu Z

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To determine whether satisfaction and health-related quality of life (HR-QoL) differ between women who do and do not undergo contralateral prophylactic mastectomy (CPM) in the setting of implant reconstruction using the BREAST-Q, a validated patient-reported outcome instrument. METHODS:From 2000 to 2007, a tot...

journal_title：Annals of surgical oncology

authors： Koslow S,Pharmer LA,Scott AM,Stempel M,Morrow M,Pusic AL,King TA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Patients undergoing cytoreductive surgery for colorectal peritoneal metastases who have a pathologic complete response (pCR) to neoadjuvant chemotherapy experience a significantly longer survival than those with residual disease. This response is known only after surgery. This study aimed to examine clinical...

journal_title：Annals of surgical oncology

authors： Bhatt A,Rousset P,Benzerdjeb N,Kammar P,Mehta S,Parikh L,Goswami G,Shaikh S,Kepenekian V,Passot G,Glehen O

更新日期：2020-11-18 00:00:00

abstract：INTRODUCTION:The moderate-penetrance germline mutations ATM, CHEK2, and PALB2 are implicated in an increased risk of the development of breast cancer. Whether these mutations provide clinical utility to guide treatment strategies and prognosis remains unknown. METHODS:A retrospective case-control study from a tertiary...

journal_title：Annals of surgical oncology

authors： Bergstrom C,Pence C,Berg J,Partain N,Sadeghi N,Mauer C,Pirzadeh-Miller S,Gao A,Li H,Unni N,Syed S

更新日期：2020-09-29 00:00:00

abstract：BACKGROUND:FOXJ1 is a member of the forkhead transcription factor family, which has been mostly studied for its role in the development of ciliated epithelium and immunology. However, the role of FOXJ1 in tumorigenesis remains largely unknown or even conflicting. We thus investigated FOXJ1 expression in gastric cancer ...

journal_title：Annals of surgical oncology

authors： Wang J,Cai X,Xia L,Zhou J,Xin J,Liu M,Shang X,Liu J,Li X,Chen Z,Nie Y,Fan D

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:RAS mutation status is an important prognostic factor after resection of liver metastases (LiM) from colorectal cancer (CRC). The prognostic significance of RAS after resection of lung (LuM) and peritoneal (PM) metastases from CRC is unknown. METHODS:Between 2005 and 2014, all consecutive patients with know...

journal_title：Annals of surgical oncology

authors： Passot G,Kim BJ,Glehen O,Mehran RJ,Kopetz SE,Goere D,Overman MJ,Pocard M,Marchal F,Conrad C,Aloia TA,Vauthey JN,Chun YS,BIG-RENAPE Working Group.

更新日期：2018-01-01 00:00:00

abstract：:Hiatal hernia (HH) is an infrequent yet potentially life-threatening complication after esophagectomy. Several studies have reported the incidence of this complication after both open and minimally invasive esophagectomy (MIE). This meta-analysis aimed to determine the pooled incidence of HH after both types of esopha...

journal_title：Annals of surgical oncology

authors： Oor JE,Wiezer MJ,Hazebroek EJ

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Studies assessing outcomes in occult breast cancer have often included women treated before the routine use of magnetic resonance imaging (MRI). This study examined outcomes for patients presenting with axillary adenopathy and no primary breast tumor detectable by MRI or other imaging methods. METHODS:All p...

journal_title：Annals of surgical oncology

authors： McCartan DP,Zabor EC,Morrow M,Van Zee KJ,El-Tamer MB

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Peritoneal metastasis of colonic origin is associated with a poor prognosis. This study aimed to analyze the clinicopathologic characteristics and prognostic predictors of survival in a cohort of patients treated with cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (POIC) during tw...

journal_title：Annals of surgical oncology

authors： Ihemelandu C,Sugarbaker PH

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Age of patients with melanoma varies directly with mortality and inversely with the presence of sentinel lymph node (SLN) metastasis. To gain further insight into this apparent paradox, we analyzed the relationship between age and other major prognostic factors. METHODS:The Sunbelt Melanoma Trial is a prosp...

journal_title：Annals of surgical oncology

authors： Chao C,Martin RC 2nd,Ross MI,Reintgen DS,Edwards MJ,Noyes RD,Hagendoorn LJ,Stromberg AJ,McMasters KM

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Epithelial cells in the bone marrow of patients with gastric cancer suggest tumor dissemination; however, their prognostic implications are controversial. We prospectively evaluated the correlation of bone marrow findings, recurrence rate, and disease-free survival after long-term follow-up. METHODS:Bone ma...

journal_title：Annals of surgical oncology

authors： Gretschel S,Schick C,Schneider U,Estevez-Schwarz L,Bembenek A,Schlag PM

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:In patients with sporadic hyperparathyroidism (HPT), radioguided parathyroidectomy (RGP) has been shown to facilitate intraoperative localization of parathyroid glands, reduced operative time, and improve patient outcomes. No studies have focused on the role of RGP in patients with familial HPT. METHODS:Bet...

journal_title：Annals of surgical oncology

authors： Lal A,Bianco J,Chen H

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The locoregional recurrence (LRR) rate after mastectomy is reported to be similar with immediate reconstruction. We aimed to identify characteristics of LRR after transverse rectus abdominis myocutaneous (TRAM) reconstruction. METHODS:We retrospectively reviewed patients undergoing immediate TRAM reconstruc...

journal_title：Annals of surgical oncology

authors： Patterson SG,Teller P,Iyengar R,Carlson GW,Gabram-Mendola SG,Losken A,Styblo T,Torres M,Wood WC,Perez SD,Mosunjac M,Rizzo M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The diagnostic phase of care is an anxiety-provoking and stressful experience for the potential breast cancer patient. A multidisciplinary team of breast cancer specialists embarked on a new initiative to pilot a Rapid Diagnosis and Support (RADS) Clinic to coordinate the diagnostic workup and nursing suppor...

journal_title：Annals of surgical oncology

authors： Arnaout A,Smylie J,Seely J,Robertson S,Knight K,Shin S,Ramsey T,Mallick R,Watters J

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Data from randomized controlled trials support use of a diverting stoma in rectal cancer patients with low anastomoses, but there is little data on how this impacts patient quality of life (QOL). This study prospectively evaluates QOL in stage I-III rectal cancer patients undergoing sphincter-preserving surg...

journal_title：Annals of surgical oncology

authors： Neuman HB,Patil S,Fuzesi S,Wong WD,Weiser MR,Guillem JG,Paty PB,Nash GM,Temple LK

更新日期：2011-05-01 00:00:00