Knockdown of thrombomodulin enhances HCC cell migration through increase of ZEB1 and decrease of E-cadherin gene expression.

abstract：BACKGROUND:Neoadjuvant chemotherapy is an accepted standard for locally advanced esophagogastric junction adenocarcinoma. However, the dysphagia frequently associated with this condition may interfere with patient tolerance of this treatment. In many centers, invasive tube feeding, placed either endoscopically, radiogr...

journal_title：Annals of surgical oncology

authors： Cools-Lartigue J,Jones D,Spicer J,Zourikian T,Rousseau M,Eckert E,Alcindor T,Vanhuyse M,Asselah J,Ferri LE

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Although perineural invasion (PNI) has been a poor prognostic factor for head and neck cancers, few studies have focused on oral squamous cell carcinoma (OSCC). The independent significance of PNI in early T1-2 OSCC and the benefit of treatment modification based on PNI status have not been assessed. This st...

journal_title：Annals of surgical oncology

authors： Tai SK,Li WY,Yang MH,Chang SY,Chu PY,Tsai TL,Wang YF,Chang PM

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Preoperative localization is the first step towards minimally invasive targeted parathyroidectomy. While there are data emphasizing that surgeon experience optimizes operative outcomes, the role of the radiologist's experience in successful preoperative imaging is unclear. We hypothesized that the accuracy o...

journal_title：Annals of surgical oncology

authors： Zia S,Sippel RS,Chen H

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The goal of this study is to report the safety and efficacy of pancreatic resection for isolated metastatic cancers from nonpancreatic primary disease. METHODS:We retrospectively identified patients from a single institution's prospectively gathered pancreaticobiliary database from 1970 to 2007 who underwen...

journal_title：Annals of surgical oncology

authors： Reddy S,Edil BH,Cameron JL,Pawlik TM,Herman JM,Gilson MM,Campbell KA,Schulick RD,Ahuja N,Wolfgang CL

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Currently, cytoreductive surgery and hyperthermic intraperitoneal chemotherapy are accepted treatments for surgically resectable appendiceal epithelial neoplasms. However, for nonsurgical candidates, systemic treatment may be considered. The purpose of this analysis was to determine the benefit of biologic t...

journal_title：Annals of surgical oncology

authors： Choe JH,Overman MJ,Fournier KF,Royal RE,Ohinata A,Rafeeq S,Beaty K,Phillips JK,Wolff RA,Mansfield PF,Eng C

更新日期：2015-08-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Goffredo P,Hassan I

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Cysteine/histidine-rich 1 (CYHR1) was first discovered in a yeast two-hybrid screen with murine galectin-3, and no previous reports have described a relationship between the CYHR1 gene and human cancer. The current study evaluated the role and significance of CYHR1 in esophageal cancer. METHODS:The human es...

journal_title：Annals of surgical oncology

authors： Desaki R,Sawada G,Okumura H,Ikeda R,Tanabe K,Komatsu H,Mimori K,Mori M,Kita Y,Uchikado Y,Arigami T,Uenosono Y,Owaki T,Ishigami S,Natsugoe S

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:A significant proportion of women who have breast-conserving surgery (BCS) subsequently undergo re-excision or proceed to mastectomy. This study aimed to identify factors associated with residual disease after repeat surgery and to determine their effect on ipsilateral breast tumor recurrence (IBTR) and surv...

journal_title：Annals of surgical oncology

authors： Bodilsen A,Bjerre K,Offersen BV,Vahl P,Ejlertsen B,Overgaard J,Christiansen P

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The importance of absent neoplastic epithelium in specimens from cytoreductive surgery (CRS) is unknown. This study aimed to investigate the prevalence and prognostic value of histopathology without neoplastic epithelium in patients treated with CRS and hyperthermic intraperitoneal chemotherapy (HIPEC). MET...

journal_title：Annals of surgical oncology

authors： Enblad M,Birgisson H,Wanders A,Sköldberg F,Ghanipour L,Graf W

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Symptomatic malignant ascites is a problem for patients with advanced intra-abdominal malignancy. Although the goal of paracentesis, the most common therapeutic intervention, is symptom palliation, the best method of assessing symptom improvement is unknown. The aim of this study was to assess the ability of...

journal_title：Annals of surgical oncology

authors： Easson AM,Bezjak A,Ross S,Wright JG

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Resectability rates for extrahepatic cholangiocarcinoma have increased over time, but long-term survival after resection alone with curative intent remains poor. Recent series suggest improved survival with adjuvant therapy. Patient subsets benefiting most from adjuvant therapy have not been clearly defined....

journal_title：Annals of surgical oncology

authors： Ecker BL,Vining CC,Roses RE,Maggino L,Lee MK,Drebin JA,Fraker DL,Vollmer CM Jr,Datta J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Repeat sentinel lymph node biopsy (rSLNB) has increasingly been used in patients with ipsilateral breast tumor recurrence (IBTR). The safety in terms of regional disease control after this procedure remains unclear. This study evaluates occurrence of regional recurrence as first event in patients with IBTR a...

journal_title：Annals of surgical oncology

authors： Poodt IGM,Vugts G,Maaskant-Braat AJG,Schipper RJ,Voogd AC,Nieuwenhuijzen GAP,Sentinel Node and Recurrent Breast Cancer (SNARB) study group.

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Hyperthermic intraperitoneal chemotherapy (HIPEC) following cytoreductive surgery is a radical but effective treatment option for patients with peritoneal carcinomatosis (PC). Unfortunately, a standardized HIPEC protocol is missing impeding systematic comparisons with regard to minimal effective temperatures...

journal_title：Annals of surgical oncology

authors： Schaaf L,van der Kuip H,Zopf W,Winter S,Münch M,Mürdter TE,Thon KP,Steurer W,Aulitzky WE,Ulmer C

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Metaplastic breast cancer (MBC) is characterized by chemoresistance and hematogenous spread. We sought to identify factors associated with improved MBC outcomes and increased likelihood of MBC diagnosis. METHODS:Women ≥ 18 years of age with stage I-III MBC and non-MBC diagnosed between 2010 and 2014 were id...

journal_title：Annals of surgical oncology

authors： Ong CT,Campbell BM,Thomas SM,Greenup RA,Plichta JK,Rosenberger LH,Force J,Hall A,Hyslop T,Hwang ES,Fayanju OM

更新日期：2018-08-01 00:00:00

abstract：:A 54-year-old woman with multiple telangiectatic hepatocellular adenoma without degeneration (>5 cm) underwent laparoscopic right hepatectomy with the hanging maneuver. The patient was installed in the supine position with the legs spread apart. Five trocars were used for the intervention. The liver hanging maneuver w...

journal_title：Annals of surgical oncology

authors： Dokmak S,Ben Safta Y,Ftériche FS,Aussilhou B,Belghiti J

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The recent introduction of biological anticancer therapy has renewed the interest in functional imaging of tumor-associated angiogenesis (TAA) as a tool to monitor early therapy response. The present study evaluated imaging of TAA using P1227, a novel, small molecular magnetic resonance imaging (MRI) probe t...

journal_title：Annals of surgical oncology

authors： Debergh I,Van Damme N,De Naeyer D,Smeets P,Demetter P,Robert P,Carme S,Pattyn P,Ceelen W

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Transection of liver parenchyma using staplers is now commonly performed. Large studies are needed to assess the usefulness of the technique as well as perioperative outcomes. METHODS:This is a retrospective study of a prospectively maintained database. A total of 1,174 patients undergoing liver resections ...

journal_title：Annals of surgical oncology

authors： Raoof M,Aloia TA,Vauthey JN,Curley SA

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Results concerning the side effects of oxaliplatin associated with fluorouracil and leucovorin (FOLFOX) in older patients are controversial. The objective of this study was to assess the use and the toxicity of FOLFOX in patients aged 70 years and older as administered in current practice. METHODS:Among 305...

journal_title：Annals of surgical oncology

authors： Hamza S,Bouvier AM,Rollot F,Lepage C,Faivre J,Bedenne L

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Adjuvant chemotherapy with 5-fluorouracil modulated by folinic acid, combined with oxaliplatin, has now become an accepted standard of care for patients with stage III colon cancer. In contrast, the use of adjuvant therapy for stage II patients remains controversial, and the identification of reliable progno...

journal_title：Annals of surgical oncology

authors： André T,Sargent D,Tabernero J,O'Connell M,Buyse M,Sobrero A,Misset JL,Boni C,de Gramont A

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The sentinel lymph node (SLN) concept has been gaining attention for gastrointestinal neoplasms but remains controversial for esophageal cancer. This study evaluated the feasibility of SLN identification using intraoperative indocyanine green (ICG) fluorescence imaging (IGFI) navigated by preoperative comput...

journal_title：Annals of surgical oncology

authors： Yuasa Y,Seike J,Yoshida T,Takechi H,Yamai H,Yamamoto Y,Furukita Y,Goto M,Minato T,Nishino T,Inoue S,Fujiwara S,Tangoku A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Long-term transcutaneous tunneled central venous catheters are frequently placed in cancer patients, accounting for significant costs and morbidity. Factors influencing outcome, though, are poorly studied. METHODS:Between June 1991 and June 1993, 923 central venous tunneled catheters were placed in 791 pati...

journal_title：Annals of surgical oncology

authors： Schwarz RE,Coit DG,Groeger JS

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Inflammation has been demonstrated to promote cancer metastasis. Due to the well-known systemic inflammatory responses (SIR) after major surgery, it is critical to investigate and attenuate SIR-induced tumor metastasis of cancer patients suffering surgical procedures. METHODS:C57BL/6 mice were intravenously...

journal_title：Annals of surgical oncology

authors： Zhang X,Moriwaki T,Kawabata T,Goto S,Liu KX,Guo CY,Li TS

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:There is substantial variation in the surgical complexity of hepatectomy. Currently, the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) risk adjusts for hospital quality comparisons using only the primary procedure code. Our objectives were to (1) assess the associatio...

journal_title：Annals of surgical oncology

authors： Paruch JL,Merkow RP,Bentrem DJ,Ko CY,Posner MC,Cohen ME,Bilimoria KY,Weber SM

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Although many experiences using the da Vinci Robot System have been reported by several groups, there is substantial controversy over the role of the robot in thyroidectomy. We performed a systematic review and meta-analyses in order to evaluate the safety and effectiveness of robotic thyroidectomy (RT) comp...

journal_title：Annals of surgical oncology

authors： Son SK,Kim JH,Bae JS,Lee SH

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Curative resection has been shown to be one of the key factors influencing survival of pancreatic ductal adenocarcinoma (PDAC) patients. Although general guidelines for the processing of pancreatic specimens have been established, there is currently no widely accepted standardized protocol for pathological e...

journal_title：Annals of surgical oncology

authors： Esposito I,Kleeff J,Bergmann F,Reiser C,Herpel E,Friess H,Schirmacher P,Büchler MW

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The decision to receive adjuvant chemotherapy is far from evident and remains controversial in patients with American Joint Committee on Cancer stage II colon cancer. This study analyzes several pathological characteristics in order to assess their (combined) predictive value for outcomes in stage II colon c...

journal_title：Annals of surgical oncology

authors： Amri R,England J,Bordeianou LG,Berger DL

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Musashi1 (Msi-1), a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Recently, aberrant expression of Msi-1 has been detected in several malignancies. However, its role in the progression of colon cancer is largely unknown. MATERIALS AND METHODS:We u...

journal_title：Annals of surgical oncology

authors： Li D,Peng X,Yan D,Tang H,Huang F,Yang Y,Peng Z

更新日期：2011-07-01 00:00:00

abstract：AIM:We evaluated preoperative serum carcinoembryonic antigen (CEA) as a prognostic factor for colorectal cancer and determined when surveillance of this marker was useful. METHODS:Serum CEA was measured preoperatively in 1,263 patients who underwent curative resection for colorectal cancer at 3-month intervals for the...

journal_title：Annals of surgical oncology

authors： Park IJ,Choi GS,Lim KH,Kang BM,Jun SH

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Remote home monitoring might fill the perceived surveillance gap after hospital discharge. However, it is unclear whether older oncologic patients will be able to use the required new digital technologies. The study aimed to assess the feasibility of postoperative remote home monitoring for this population. ...

journal_title：Annals of surgical oncology

authors： Jonker LT,Plas M,de Bock GH,Buskens E,van Leeuwen BL,Lahr MMH

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Improved survival has been reported for diffuse malignant peritoneal mesothelioma (DMPM) treated by surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC). The significance of lymph node involvement in this disease is still poorly understood. METHODS:Prospectively collected clinical da...

journal_title：Annals of surgical oncology

authors： Baratti D,Kusamura S,Cabras AD,Laterza B,Balestra MR,Deraco M

更新日期：2010-01-01 00:00:00