Most pancreatic cancer resections are R1 resections.

abstract：BACKGROUND:Extraskeletal myxoid chondrosarcoma (EMC) is a rare sarcoma of uncertain origin, marked by specific chromosomal translocations involving the NR4A3 gene, and usually characterized by an indolent course. Surgery (with or without radiotherapy) is the treatment of choice in localized disease. The treatment for a...

journal_title：Annals of surgical oncology

authors： Paioli A,Stacchiotti S,Campanacci D,Palmerini E,Frezza AM,Longhi A,Radaelli S,Donati DM,Beltrami G,Bianchi G,Barisella M,Righi A,Benini S,Fiore M,Picci P,Gronchi A

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:The standard treatment for patients 75 years of age or younger with cStage 2 or 3 esophageal cancer is preoperative chemotherapy followed by esophagectomy. The optimal treatment for elderly patients, especially those considered vulnerable, remains unclear. METHODS:This study retrospectively reviewed the dat...

journal_title：Annals of surgical oncology

authors： Booka E,Haneda R,Ishii K,Tsushima T,Yasui H,Tsubosa Y

更新日期：2020-09-02 00:00:00

abstract：BACKGROUND:Peritoneal metastases portend poor prognosis in the setting of standard chemotherapy. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) improves outcomes, but relapse is common. We report a phase II trial evaluating the safety and efficacy of adjuvant αDC1 vaccination with chemo...

journal_title：Annals of surgical oncology

authors： Ramanathan R,Choudry H,Jones H,Girgis M,Gooding W,Kalinski P,Bartlett DL

更新日期：2021-01-05 00:00:00

abstract：:Barrett's esophagus (BE) is a premalignant lesion known to sequentially progress to esophageal adenocarcinoma. Management of BE has changed significantly over the last 5 years with the development of endoscopic resection and ablation, which has replaced esophagectomy as the treatment of choice in BE with high-grade dy...

journal_title：Annals of surgical oncology

authors： Dunki-Jacobs EM,Martin RC

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Gastric cancer is one of the most common gastrointestinal malignancies world-wide. Some studies have suggested that it has a worse prognosis in young than in elderly patients. METHODS:All young and elderly patients treated for gastric adenocarcinoma during the period 1988 to 1994 in a tertiary referral cent...

journal_title：Annals of surgical oncology

authors： Medina-Franco H,Heslin MJ,Cortes-Gonzalez R

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Angiotensin 2 is a key biologic peptide in the renin-angiotensin system (RAS) that regulates blood pressure and renal hemodynamics. The potential role of the RAS in the promotion of tumor growth, angiogenesis, and metastasis also has been shown in the past few decades. This study investigated the prognostic ...

journal_title：Annals of surgical oncology

authors： Miyajima A,Yazawa S,Kosaka T,Tanaka N,Shirotake S,Mizuno R,Kikuchi E,Oya M

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the prognostic impact of pT2 subclassification according to the depth of muscularis propria (MP) invasion and to explore the clinicopathologic factors correlated with lymph node metastasis (LNM) and postoperative hematogenous metastasis in pT2 colorectal cancer. METHODS:A total ...

journal_title：Annals of surgical oncology

authors： Tong LL,Gao P,Wang ZN,Yue ZY,Song YX,Sun Z,Lu Y,Xing CZ,Xu HM

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Inflammatory breast cancer (IBC) is an aggressive disease that is treated with trimodality therapy consisting of neoadjuvant chemotherapy, surgery, and post-mastectomy radiation therapy (PMRT). Traditionally, modified radical mastectomy without reconstruction has been the operation of choice for patients wit...

journal_title：Annals of surgical oncology

authors： Simpson AB,McCray D,Wengler C,Crowe JP,Djohan R,Tendulkar R,O'Rourke C,Grobmyer SR,Valente SA

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Primary breast cancers that overexpress human epidermal growth factor receptor 2 have variable biological features and clinical outcomes. A subgroup of HER2-overexpressing tumors that express basal-like immunohistochemical markers-the so-called basal-HER2+ subtype--is associated with poor prognosis. We inves...

journal_title：Annals of surgical oncology

authors： Bagaria SP,Ray PS,Wang J,Kropcho L,Chung A,Sim MS,Shamonki JM,Martino S,Cui X,Giuliano AE

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Trastuzumab in association with systemic cytotoxic chemotherapy is the standard of care for patients with advanced HER2-positive gastric carcinoma (GC). However, HER2 as a prognostic factor in GC remains controversial. METHODS:HER2 overexpression and amplification was evaluated by immunohistochemistry (IHC)...

journal_title：Annals of surgical oncology

authors： Cho J,Jeong J,Sung J,Sung CO,Kim KM,Park CK,Choi MG,Sohn TS,Bae JM,Kim S

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Currently, cytoreductive surgery and hyperthermic intraperitoneal chemotherapy are accepted treatments for surgically resectable appendiceal epithelial neoplasms. However, for nonsurgical candidates, systemic treatment may be considered. The purpose of this analysis was to determine the benefit of biologic t...

journal_title：Annals of surgical oncology

authors： Choe JH,Overman MJ,Fournier KF,Royal RE,Ohinata A,Rafeeq S,Beaty K,Phillips JK,Wolff RA,Mansfield PF,Eng C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Positive peritoneal cytology is a predictor of poor survival in patients with gastric cancer. Our aim is to more clearly define the natural history of this cohort. METHODS:Review of a prospectively maintained gastric cancer database of patients who had diagnostic laparoscopy with peritoneal washings. Clinic...

journal_title：Annals of surgical oncology

authors： Mezhir JJ,Shah MA,Jacks LM,Brennan MF,Coit DG,Strong VE

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Most melanoma patients present with thin (

journal_title：Annals of surgical oncology

authors： Karakousis GC,Gimotty PA,Botbyl JD,Kesmodel SB,Elder DE,Elenitsas R,Ming ME,Guerry D,Fraker DL,Czerniecki BJ,Spitz FR

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:0.6-12.7% of patients with primary cutaneous melanoma will develop additional melanomas. Pathologic features of tumors in patients with multiple primary cutaneous melanomas have not been well described. In this large, international, multicenter, case-control study, we compared the clinicopathologic features ...

journal_title：Annals of surgical oncology

authors： Murali R,Goumas C,Kricker A,From L,Busam KJ,Begg CB,Dwyer T,Gruber SB,Kanetsky PA,Orlow I,Rosso S,Thomas NE,Berwick M,Scolyer RA,Armstrong BK,GEM Study Group.

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:To report feasibility, tolerance, anatomical topography of locoregional recurrence (LRR), and long-term outcome for esophageal and esophagogastric (EG) cancer patients treated with preoperative chemoradiation (CRT) and surgery with or without a radiation boost of intraoperative electron beam radiotherapy (IO...

journal_title：Annals of surgical oncology

authors： Calvo FA,Sole CV,Obregón R,Gómez-Espí M,Lozano MA,Gonzalez-Bayon L,García-Sabrido JL

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Repeat sentinel lymph node biopsy (rSLNB) has increasingly been used in patients with ipsilateral breast tumor recurrence (IBTR). The safety in terms of regional disease control after this procedure remains unclear. This study evaluates occurrence of regional recurrence as first event in patients with IBTR a...

journal_title：Annals of surgical oncology

authors： Poodt IGM,Vugts G,Maaskant-Braat AJG,Schipper RJ,Voogd AC,Nieuwenhuijzen GAP,Sentinel Node and Recurrent Breast Cancer (SNARB) study group.

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Ultrasonography and fine-needle aspiration (FNA) are used to evaluate the breast and regional nodes in breast cancer patients. We sought to identify factors influencing the sensitivity of ultrasonography for detection of nodal metastasis. METHODS:Patients with a clinically negative axilla who underwent axil...

journal_title：Annals of surgical oncology

authors： Bedrosian I,Bedi D,Kuerer HM,Fornage BD,Harker L,Ross MI,Ames FC,Krishnamurthy S,Edeiken-Monroe BS,Meric F,Feig BW,Akins J,Singletary SE,Mirza NQ,Hunt KK

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Despite the potential for residual lymph node metastases after a negative or positive sentinel lymph node biopsy (SLNB), breast cancer patients rarely experience regional recurrences (RRs). This study aimed to quantify the effects of nonsurgical treatments on RR incidence among SLNB-negative (SLNB N0) breast...

journal_title：Annals of surgical oncology

authors： van Steenhoven JEC,Kuijer A,van Maaren MC,Roos M,Elias SG,van Diest PJ,Siesling S,Smidt ML,Boersma LJ,van Dalen T

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Breast cancers (BCs) diagnosed after a recent pregnancy display features associated with poor prognosis, including hormone receptor negativity, but other tumor markers have not been examined. We sought to define the tumor marker profile of these cancers, including HER-2 and p53 expression, and examine the ti...

journal_title：Annals of surgical oncology

authors： Pilewskie M,Gorodinsky P,Fought A,Hansen N,Bethke K,Jeruss J,Scholtens D,Khan SA

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The treatment of Wilms' tumor has undergone major advances in the past four decades. Current therapy is based on both the stage and pathology of the tumor. We have reviewed our recent experience with this tumor to assess the results of treatment on protocols that generally avoid the use of doxorubicin. METH...

journal_title：Annals of surgical oncology

authors： Shamberger RC,Macklis RM,Sallan SE

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Health care reform places primary care (PC) physicians in an increasingly significant role for breast cancer screening and diagnosis. This study assessed the adequacy of traditional PC resident training to prepare physicians for this front-line role. METHODS:Sixty-eight primary care residents, representing ...

journal_title：Annals of surgical oncology

authors： Chalabian J,Formenti S,Russell C,Pearce J,Dunnington G

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Hyperbilirubinemia is commonly observed in patients requiring pancreatoduodenectomy (PD). Thus far, literature regarding the danger of operating in the setting of hyperbilirubinemia is equivocal. What remains undefined is at what specific level of bilirubin there is an adverse safety profile for undergoing P...

journal_title：Annals of surgical oncology

authors： Chen B,Trudeau MT,Maggino L,Ecker BL,Keele LJ,DeMatteo RP,Drebin JA,Fraker DL,Lee MK 4th,Roses RE,Vollmer CM Jr

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Dickkopf-1 (DKK1) is the inhibitor of the canonical Wnt signaling pathway, however it is highly transactivated in various cancers, suggesting the presence of unknown mechanism. Its implication in human esophageal squamous cell carcinoma (ESCC) has not been sufficiently investigated. PATIENTS ...

journal_title：Annals of surgical oncology

authors： Makino T,Yamasaki M,Takemasa I,Takeno A,Nakamura Y,Miyata H,Takiguchi S,Fujiwara Y,Matsuura N,Mori M,Doki Y

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Results concerning the side effects of oxaliplatin associated with fluorouracil and leucovorin (FOLFOX) in older patients are controversial. The objective of this study was to assess the use and the toxicity of FOLFOX in patients aged 70 years and older as administered in current practice. METHODS:Among 305...

journal_title：Annals of surgical oncology

authors： Hamza S,Bouvier AM,Rollot F,Lepage C,Faivre J,Bedenne L

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Appendiceal goblet cell adenocarcinoma (GCA) is often misclassified and mistreated due to mixed histologic features. In general, cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is standard of care for peritoneal carcinomatosis (PC) from mucinous appendiceal tumors; however, i...

journal_title：Annals of surgical oncology

authors： Zambrano-Vera K,Sardi A,Munoz-Zuluaga C,Studeman K,Nieroda C,Sittig M,King MC,Sipok A,Gushchin V

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Liver kinase B1 (LKB1) loss by gene mutation, loss of heterozygosity, and promoter methylation rarely occurs in colorectal cancer. We wondered whether LKB1 loss could be deregulated at the transcriptional level to promote tumor progression and poor outcome in colorectal cancer. METHODS:Mechanistic studies w...

journal_title：Annals of surgical oncology

authors： He TY,Tsai LH,Huang CC,Chou MC,Lee H

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Identification of melanoma patients who need completion lymphadenectomy and adjuvant treatment after positive sentinel lymph node (SLN) biopsy would be a fundamental step forward toward personalized medicine. This study tested the hypothesis that the microscopic features of metastatic SLNs might predict not ...

journal_title：Annals of surgical oncology

authors： Rossi CR,De Salvo GL,Bonandini E,Mocellin S,Foletto M,Pasquali S,Pilati P,Lise M,Nitti D,Rizzo E,Montesco MC

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Whether breast cancer surgeons are adequately trained, skilled, and experienced to provide breast cancer genetic assessment, testing, and counseling came under debate in September 2013 when a major third-party payer excluded nongenetics specialists from ordering such testing. A literature search having faile...

journal_title：Annals of surgical oncology

authors： Beitsch PD,Whitworth PW

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Not all patients respond equally to neoadjuvant chemoradiotherapy (nCRT), with subsequent effects on survival. The systemic inflammatory response has been shown to predict long-term outcomes in colorectal cancer. The current study examined the association between systemic inflammation and nCRT in patients wi...

journal_title：Annals of surgical oncology

authors： Dreyer SB,Powell AG,McSorley ST,Waterston A,Going JJ,Edwards J,McMillan DC,Horgan PG

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Among all in-breast tumor recurrences (IBTR) following breast-conserving therapy (BCT), some comprise metachronous new primaries (NPs) while others are true recurrences (TRs). Establishing this distinction remains a challenge. METHODS:We studied 3932 women who underwent BCT for stage I-III breast cancer fro...

journal_title：Annals of surgical oncology

authors： Laird J,Lok B,Siu C,Cahlon O,Khan AJ,McCormick B,Powell SN,Cody H,Wen HY,Ho A,Braunstein LZ

更新日期：2018-01-01 00:00:00