Is pT2 subclassification feasible to predict patient outcome in colorectal cancer?

abstract：BACKGROUND:There is no consensus as to the impact of lymph node micrometastasis on survival of patients with gastric cancer. The aim of this study was to clarify the prognostic significance of lymph node micrometastasis in patients with histologically node-negative gastric cancer. METHODS:Lymph nodes (n = 2039) from 6...

journal_title：Annals of surgical oncology

authors： Yasuda K,Adachi Y,Shiraishi N,Inomata M,Takeuchi H,Kitano S

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Considering the typical rapid progression and high mortality of pancreatic cancer (PC), early detection may lead to an improved outcome. To date, there is no safe, sensitive, and cost-effective screening strategy to detect PC. Currently, screening is focused on individuals at the highest risk of developing P...

journal_title：Annals of surgical oncology

authors： Catts ZA,Baig MK,Milewski B,Keywan C,Guarino M,Petrelli N

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Management of patients with neuroendocrine liver metastasis (NELM) remains controversial. We sought to examine the relative efficacy of surgical management versus intra-arterial therapy (IAT) for NELM and determine factors predictive of survival. METHODS:A total of 753 patients who had surgery (n = 339) or ...

journal_title：Annals of surgical oncology

authors： Mayo SC,de Jong MC,Bloomston M,Pulitano C,Clary BM,Reddy SK,Clark Gamblin T,Celinski SA,Kooby DA,Staley CA,Stokes JB,Chu CK,Arrese D,Ferrero A,Schulick RD,Choti MA,Geschwind JF,Strub J,Bauer TW,Adams RB,Aldrighett

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:CA 19-9 levels are useful for the diagnosis of patients with pancreatic adenocarcinoma. However, interest has recently turned toward its use as a prognostic indicator. The purpose of this study is to determine whether postoperative CA 19-9 levels predict disease-free survival (DFS) and median survival (MS) i...

journal_title：Annals of surgical oncology

authors： Montgomery RC,Hoffman JP,Riley LB,Rogatko A,Ridge JA,Eisenberg BL

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Secretory carcinoma is a distinctive and rare variant of breast carcinoma with a favorable prognosis because these tumors usually behave in an indolent manner. The occurrence of this type of breast cancer in males was studied. METHODS:An extensive literature survey concerning secretory breast cancer in male...

journal_title：Annals of surgical oncology

authors： de Bree E,Askoxylakis J,Giannikaki E,Chroniaris N,Sanidas E,Tsiftsis DD

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Patients with periampullary cancer frequently suffer obstructive jaundice and commonly require preoperative biliary drainage (PBD) for relief and to avoid related complications. Although research has established a correlation between PBD and surgical wound infection, the impact of PBD on major infectious com...

journal_title：Annals of surgical oncology

authors： Wu JM,Ho TW,Yen HH,Wu CH,Kuo TC,Yang CY,Tien YW

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:In the Netherlands, a maximum waiting time from diagnosis to treatment (WT) of 5 weeks is recommended for curative cancer treatment. This study aimed to evaluate the association between WT and overall survival (OS) in patients undergoing gastrectomy for cancer. METHODS:This nationwide study included data fr...

journal_title：Annals of surgical oncology

authors： Brenkman HJF,Visser E,van Rossum PSN,Siesling S,van Hillegersberg R,Ruurda JP

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:RAS mutation status predicts survival after hepatectomy for colorectal liver metastases (CRLM) and survival after repeat hepatectomy for intrahepatic recurrence. This study was aimed at determining the impact of RAS mutation on amenability of recurrence to local therapy and on post-recurrence survival follow...

journal_title：Annals of surgical oncology

authors： Okuno M,Goumard C,Kopetz S,Vega EA,Joechle K,Mizuno T,Omichi K,Tzeng CD,Chun YS,Vauthey JN,Conrad C

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:With the recent development of molecular markers, it has become possible to characterize colorectal carcinomas beyond clinical and histologic aspects. When considered together with tumor stage, molecular markers will allow us further insight into individual tumor biologies and prognoses. PURPOSE:To investig...

journal_title：Annals of surgical oncology

authors： Kang H,Min BS,Lee KY,Kim NK,Kim SN,Choi J,Kim H

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:Atypical protein kinase C iota (aPKC-iota) and its associated intracellular molecules, E-cadherin and beta-catenin, are important for cell polarization in tumorigenesis and progression. Expression of aPKC-iota, P-aPKC-iota (activated aPKC-iota), E-cadherin, and beta-catenin in hepatocellular carcinoma (HCC) ...

journal_title：Annals of surgical oncology

authors： Du GS,Wang JM,Lu JX,Li Q,Ma CQ,Du JT,Zou SQ

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The impact of cardiorespiratory comorbidity on operative outcomes after esophagectomy remains controversial. This study investigated the effect of cardiorespiratory comorbidity on postoperative complications for patients treated for esophageal or gastroesophageal junction cancer. PATIENTS AND METHODS:A Euro...

journal_title：Annals of surgical oncology

authors： Klevebro F,Elliott JA,Slaman A,Vermeulen BD,Kamiya S,Rosman C,Gisbertz SS,Boshier PR,Reynolds JV,Rouvelas I,Hanna GB,van Berge Henegouwen MI,Markar SR

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Extraskeletal myxoid chondrosarcoma (EMC) is a rare sarcoma of uncertain origin, marked by specific chromosomal translocations involving the NR4A3 gene, and usually characterized by an indolent course. Surgery (with or without radiotherapy) is the treatment of choice in localized disease. The treatment for a...

journal_title：Annals of surgical oncology

authors： Paioli A,Stacchiotti S,Campanacci D,Palmerini E,Frezza AM,Longhi A,Radaelli S,Donati DM,Beltrami G,Bianchi G,Barisella M,Righi A,Benini S,Fiore M,Picci P,Gronchi A

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Pleomorphic carcinomas of the lung are uncommon malignant tumors composed of carcinomatous and sarcomatous components and are distinguished from other non-small-cell lung carcinomas by a more aggressive clinical course with early distant metastases and far worse survival. Epidermal growth factor receptor (EG...

journal_title：Annals of surgical oncology

authors： Chang YL,Wu CT,Shih JY,Lee YC

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Hyperthermic intraperitoneal chemotherapy (HIPEC) and complete surgical removal of the tumor, in relapsing patients may provide a clinical benefit. There is no consensus considering the place of HIPEC for patients who had first ovarian cancer relapse. To assess for possible efficacy of HIPEC on overall survi...

journal_title：Annals of surgical oncology

authors： Le Brun JF,Campion L,Berton-Rigaud D,Lorimier G,Marchal F,Ferron G,Oger AS,Dravet F,Jaffre I,Classe JM

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:We investigated the effects of telomerase inhibition by using the reverse transcriptase inhibitor azidothymidine (AZT) in the human colorectal cancer cell line HT-29 in the presence and absence of 5-fluorouracil (5-FU). METHODS:HT-29 cells were cultured in the presence of AZT. Telomerase activity was measur...

journal_title：Annals of surgical oncology

authors： Brown T,Sigurdson E,Rogatko A,Broccoli D

更新日期：2003-10-01 00:00:00

abstract：:Isolated hepatic perfusion (IHP) is a proven approach for regional delivery of chemotherapy in patients with unresectable primary and metastatic tumors of the liver. Most trials of IHP have utilized melphalan as the active drug in the perfusate. We performed a phase I trial to evaluate the efficacy, safety, and maximu...

journal_title：Annals of surgical oncology

authors： Zeh HJ 3rd,Brown CK,Holtzman MP,Egorin MJ,Holleran JL,Potter DM,Bartlett DL

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Curative resection has been shown to be one of the key factors influencing survival of pancreatic ductal adenocarcinoma (PDAC) patients. Although general guidelines for the processing of pancreatic specimens have been established, there is currently no widely accepted standardized protocol for pathological e...

journal_title：Annals of surgical oncology

authors： Esposito I,Kleeff J,Bergmann F,Reiser C,Herpel E,Friess H,Schirmacher P,Büchler MW

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Goblet cell carcinoma (GCC) of the appendix is a rare disease. Treatment options vary according to disease staging. Cytoreductive surgery in combination with hyperthermic intraperitoneal chemotherapy (CRS + HIPEC) may improve survival in patients with peritoneal spreading. OBJECTIVE:The aim of this study wa...

journal_title：Annals of surgical oncology

authors： Madsen AH,Ladekarl M,Villadsen GE,Grønbæk H,Sørensen MM,Stribolt K,Verwaal VJ,Iversen LH

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Survival for Child's A patients with hepatocellular cancer (HCC) and macroscopic vascular invasion (MVI) has been reported as approximately 8.1 months with sorafenib. The role of surgery for these patients remains controversial. METHODS:The records of all patients undergoing resection of HCC at a single cen...

journal_title：Annals of surgical oncology

authors： Roayaie S,Jibara G,Taouli B,Schwartz M

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Recent data suggest sentinel lymph node biopsy (SLNBx) for invasive breast cancer (IBC) is widely performed in the United States, often outside of a clinical trial. We sought to describe SLNBx practice patterns in Canada, as well as criteria for abandonment of concurrent axillary lymph node dissection. METH...

journal_title：Annals of surgical oncology

authors： Porter GA,McMulkin H,Lovrics PJ

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:The enhanced esthetics and demonstrated oncologic safety of nipple-sparing mastectomy (NSM) in selected patients have resulted in increased rates among patients with locally advanced breast cancer and/or additional risk factors (obesity, prior radiation, surgery). Limited data exist on complication and recon...

journal_title：Annals of surgical oncology

authors： Young WA,Degnim AC,Hoskin TL,Jakub JW,Nguyen MD,Tran NV,Harless CA,Manrique OJ,Boughey JC,Hieken TJ

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Hepatic artery infusion (HAI) chemotherapy is an effective regional therapy for unresectable colorectal liver metastases (U-CRLM).1 , 2 One of its limitations is the need for a laparotomy, which can delay the use of systemic therapy.3 Here, we describe a purely robotic technique for placement of an HAI pump ...

journal_title：Annals of surgical oncology

authors： Dhir M,Magge D,Novak S,Bartlett DL,Zureikat AH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Results concerning the side effects of oxaliplatin associated with fluorouracil and leucovorin (FOLFOX) in older patients are controversial. The objective of this study was to assess the use and the toxicity of FOLFOX in patients aged 70 years and older as administered in current practice. METHODS:Among 305...

journal_title：Annals of surgical oncology

authors： Hamza S,Bouvier AM,Rollot F,Lepage C,Faivre J,Bedenne L

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Hospital readmissions and reoperations are quality indicators of patient care. In 2012, the National Surgical Quality Improvement Program (ACS-NSQIP) began reporting details regarding unplanned reoperations within 30 days of initial procedure. The main objective of this study was to identify reoperation rate...

journal_title：Annals of surgical oncology

authors： Al-Hilli Z,Thomsen KM,Habermann EB,Jakub JW,Boughey JC

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Total cystectomy is indicated for the treatment of bulky primary rectal cancers as well as previously treated, locally recurrent tumors that invade the bladder, prostate, seminal vesicle, or urethra. We review a 10-year Memorial Sloan-Kettering Cancer Center experience with urinary diversion in this setting....

journal_title：Annals of surgical oncology

authors： Russo P,Ravindran B,Katz J,Paty P,Guillem J,Cohen AM

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:RAS mutation status is an important prognostic factor after resection of liver metastases (LiM) from colorectal cancer (CRC). The prognostic significance of RAS after resection of lung (LuM) and peritoneal (PM) metastases from CRC is unknown. METHODS:Between 2005 and 2014, all consecutive patients with know...

journal_title：Annals of surgical oncology

authors： Passot G,Kim BJ,Glehen O,Mehran RJ,Kopetz SE,Goere D,Overman MJ,Pocard M,Marchal F,Conrad C,Aloia TA,Vauthey JN,Chun YS,BIG-RENAPE Working Group.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Isolated hepatic perfusion (IHP) of chemotherapy has been proposed to deliver high doses of drug while avoiding systemic toxicity. Hypotonic cisplatin has a high in vitro activity on human colon cancer cells. We studied the safety of a 30-min hypoxic single-pass IHP with hypotonic cisplatin. METHODS:A preli...

journal_title：Annals of surgical oncology

authors： Ortega-Deballon P,Facy O,Consolo D,Magnin G,Tixier H,Simonet M,Rat P,Chauffert B

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Prostate cancer is often diagnosed early enough in its clinical course to permit radical prostatectomy to be done with curative intent, yet many patients experience tumor recurrence. Most patients receive postoperative surveillance, but the intensity of testing varies appreciably. We sought to evaluate the i...

journal_title：Annals of surgical oncology

authors： Powell TM,Thompsen JP,Virgo KS,Johnson ET,Chan D,Colberg JW,Ornstein DK,Johnson FE

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:The quality of decision-making in cancer multidisciplinary team (MDT) meetings is variable, which can result in suboptimal clinical decision making. We developed MDT-QuIC, an evidence-based tool to support clinical decision making by MDTs, which was evaluated by key users. METHODS:Following a literature rev...

journal_title：Annals of surgical oncology

authors： Lamb BW,Sevdalis N,Vincent C,Green JS

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Clinical trials report improved overall survival following neoadjuvant chemoradiotherapy in patients undergoing surgery for esophageal adenocarcinoma, with a 10-15% survival improvement. MicroRNAs (miRNAs) are small noncoding RNAs that are known to direct the behavior of cancers, including response to treatm...

journal_title：Annals of surgical oncology

authors： Chiam K,Mayne GC,Watson DI,Woodman RJ,Bright TF,Michael MZ,Karapetis CS,Irvine T,Phillips WA,Hummel R,Wang T,Pimlott LK,Marri S,Astill DS,Ruszkiewicz AR,Thompson SK,Hussey DJ

更新日期：2018-09-01 00:00:00