Phase II Trial of Adjuvant Dendritic Cell Vaccine in Combination with Celecoxib, Interferon-α, and Rintatolimod in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases.

abstract：PURPOSE:Neuropathic pain (NPP) following breast surgery extends morbidity in the postoperative period. The incidence and etiology of postoperative NPP remains unclear and under-reported in literature. This study aims to define the incidence of neuropathic pain following breast surgery and to identify patient characteri...

journal_title：Annals of surgical oncology

authors： Wilson GC,Quillin RC 3rd,Hanseman DJ,Lewis JD,Edwards MJ,Shaughnessy EA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Notch1 regulates cell proliferation, development, and apoptosis. Aberrant expression of Notch1 has been discovered in many types of tumors. We examined Notch1 expression in colorectal cancer to assess its role as a prognostic indicator. METHODS:Notch1 protein expression was examined by immunohistochemistry ...

journal_title：Annals of surgical oncology

authors： Chu D,Li Y,Wang W,Zhao Q,Li J,Lu Y,Li M,Dong G,Zhang H,Xie H,Ji G

更新日期：2010-05-01 00:00:00

abstract：PURPOSE:Rates of both unilateral (UM) and contralateral prophylactic mastectomy (CPM) for unilateral early-stage breast cancer (ESBC) have been increasing since 2003. Recent studies suggest that this increase may be due to women choosing UM and CPM because of fear. We conducted an in-depth qualitative study to identify...

journal_title：Annals of surgical oncology

authors： Covelli AM,Baxter NN,Fitch MI,McCready DR,Wright FC

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The lymph node (LN) ratio (LNR) and the log odds of positive LNs (LODDS) have been proposed as sensitive prognosticators in patients with primary gastric cancer, especially in patients with an insufficient number of harvested LNs. We investigated the association of LNR and LODDS with survival in patients wit...

journal_title：Annals of surgical oncology

authors： Kano K,Yamada T,Yamamoto K,Komori K,Watanabe H,Takahashi K,Maezawa Y,Fujikawa H,Numata M,Aoyama T,Tamagawa H,Cho H,Yukawa N,Yoshikawa T,Rino Y,Masuda M,Ogata T,Oshima T

更新日期：2021-01-03 00:00:00

abstract：PURPOSE:We sought to examine how splenectomy as part of up-front cytoreductive surgery in ovarian cancer influences the postoperative course and affects survival. METHODS:We reviewed cases of ovarian cancer diagnosed at Massachusetts General Hospital from 1994 to 2008 and found 44 patients who had a splenectomy as par...

journal_title：Annals of surgical oncology

authors： McCann CK,Growdon WB,Munro EG,Del Carmen MG,Boruta DM,Schorge JO,Goodman A

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Identification of gastric cancer-related molecules is necessary to elucidate the pathological mechanisms of this heterogeneous disease. The purpose of this study was to identify novel genes associated with aggressive phenotypes of gastric cancer. METHODS:Global expression profiling was conducted using tissu...

journal_title：Annals of surgical oncology

authors： Uno Y,Kanda M,Miwa T,Umeda S,Tanaka H,Tanaka C,Kobayashi D,Suenaga M,Hattori N,Hayashi M,Yamada S,Nakayama G,Fujiwara M,Kodera Y

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Resection of melanoma metastatic to the liver remains controversial. We evaluated the efficacy of hepatic resection in patients with metastatic ocular and cutaneous melanoma and assessed factors that could affect survival after resection. METHODS:Forty patients with hepatic melanoma metastasis underwent res...

journal_title：Annals of surgical oncology

authors： Pawlik TM,Zorzi D,Abdalla EK,Clary BM,Gershenwald JE,Ross MI,Aloia TA,Curley SA,Camacho LH,Capussotti L,Elias D,Vauthey JN

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The prognosis of patients with peritoneally metastasized colorectal cancer has improved significantly with the introduction of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (CRS + HIPEC). Although a macroscopically complete resection is achieved in nearly every patient, recurren...

journal_title：Annals of surgical oncology

authors： Simkens GA,van Oudheusden TR,Luyer MD,Nienhuijs SW,Nieuwenhuijzen GA,Rutten HJ,de Hingh IH

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Postoperative changes after axillary lymph node surgery may significantly alter breast cancer survivors' (BCS) quality of life. Although sentinel lymph node biopsy (SLNB) has less immediate morbidity than axillary lymph node dissection (ALND), its long-term impact on shoulder abduction, arm swelling, and neu...

journal_title：Annals of surgical oncology

authors： Crane-Okada R,Wascher RA,Elashoff D,Giuliano AE

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the introduction of diagnostic laparoscopy (DLS) in patients with colorectal peritoneal metastases (PM) to prevent non-therapeutic laparotomies during cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS + HIPEC). METHODS:Patients with histologically...

journal_title：Annals of surgical oncology

authors： Hentzen JEKR,Constansia RDN,Been LB,Hoogwater FJH,van Ginkel RJ,van Dam GM,Hemmer PHJ,Kruijff S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Extension of lymphadenectomy in gastric cancer is controversial, and preoperative diagnosis of lymph node metastases (LNM) is difficult. Therefore, knowledge-based systems such as the Maruyama computer program (MCP) are being developed. MCP shows good prognostic value for the compartments; however, for diffe...

journal_title：Annals of surgical oncology

authors： Bollschweiler EH,Mönig SP,Hensler K,Baldus SE,Maruyama K,Hölscher AH

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the impact that the release of consensus guidelines for margins in breast-conserving surgery (BCS) had on re-excision rates. METHODS:A retrospective review examined a prospectively maintained database of patients who had operable invasive breast cancer treated with BCS at the au...

journal_title：Annals of surgical oncology

authors： Chung A,Gangi A,Amersi F,Bose S,Zhang X,Giuliano A

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:This study investigated the effects of preoperative chemoradiotherapy (PCRT) and the prognoses of patients with mucinous rectal cancer compared with those with nonmucinous cancer. METHODS:We retrospectively reviewed the medical records of 368 patients who underwent curative resection after PCRT, between 200...

journal_title：Annals of surgical oncology

authors： Shin US,Yu CS,Kim JH,Kim TW,Lim SB,Yoon SN,Yoon YS,Kim CW,Kim JC

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Medical photography has become an important component of the evaluation and management of patients across many specialties. It is increasingly utilized in contemporary practice with modern smartphones and enhanced digital media. Photography can enhance and improve treatment plans and communication between pr...

journal_title：Annals of surgical oncology

authors： Nguyen TT,VanderWalde L,Bellavance E,Eisenhauer T,Hieken T,Johnson N,Kaufman DI,O'Neill J,Patten CR,Teller P,Tevis S,Sarantou T,Throckmorton A

更新日期：2018-10-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Chan DL,Hallet J

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Postoperative complications are associated with poor cancer-specific survival in various types of cancer surgery. Recent studies suggest that systemic inflammation induced by surgical trauma can accelerate the adhesion of circulating tumor cells to the vascular endothelium of distant organs, resulting in ear...

journal_title：Annals of surgical oncology

authors： Nojiri T,Hamasaki T,Inoue M,Shintani Y,Takeuchi Y,Maeda H,Okumura M

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Tissue destruction by cryosurgery not only is mediated by direct cell damage, but also involves secondary mechanisms, such as ischemia due to shutdown of the microcirculation. Clinicians favor repetitive cryoapplication, although there is no proven evidence for a more effective tumor eradication. METHODS:Th...

journal_title：Annals of surgical oncology

authors： Richter S,Pistorius G,Seidel R,Feifel G,Schilling MK,Vollmar B,Menger MD

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:There is a continuous interest in the literature concerning the management and survival after treatment of local recurrence in sarcomas because it is one of the most common types of recurrence. DESIGN:We retrospectively reviewed 93 patients treated for local recurrence from soft-tissue sarcoma. METHODS:We ...

journal_title：Annals of surgical oncology

authors： Karakousis CP,Proimakis C,Rao U,Velez AF,Driscoll DL

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Patients undergoing cytoreductive surgery for colorectal peritoneal metastases who have a pathologic complete response (pCR) to neoadjuvant chemotherapy experience a significantly longer survival than those with residual disease. This response is known only after surgery. This study aimed to examine clinical...

journal_title：Annals of surgical oncology

authors： Bhatt A,Rousset P,Benzerdjeb N,Kammar P,Mehta S,Parikh L,Goswami G,Shaikh S,Kepenekian V,Passot G,Glehen O

更新日期：2020-11-18 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the correlation between clinical complete response (cCR) and pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) for esophageal squamous cell cancer (ESCC). METHODS:Between May 2001 and April 2013, a total of 158 patients with thoracic ESCC tr...

journal_title：Annals of surgical oncology

authors： Liu SL,Xi M,Yang H,Yang YD,Wu YJ,Zhao L,Zhang P,Luo LL,Liu MZ

更新日期：2016-01-01 00:00:00

abstract：:Selected patients with hepatocellular carcinoma are candidates to receive potentially curative treatments, such as hepatic resection or liver transplantation, but nevertheless there is a high risk of tumor recurrence. Microvascular invasion is a histological feature of hepatocellular carcinoma related to aggressive bi...

journal_title：Annals of surgical oncology

authors： Rodríguez-Perálvarez M,Luong TV,Andreana L,Meyer T,Dhillon AP,Burroughs AK

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The rising incidence of incidental thyroid carcinoma (ITC) detected during fluoro-2-deoxy-D: -glucose (FDG)-positron emission tomography (PET)/computed tomography (CT) scanning poses a challenge to clinicians. The present study aims to critically evaluate the clinicopathological characteristics of ITC detect...

journal_title：Annals of surgical oncology

authors： Law TT,Lang BH

更新日期：2011-02-01 00:00:00

abstract：AIM:We evaluated preoperative serum carcinoembryonic antigen (CEA) as a prognostic factor for colorectal cancer and determined when surveillance of this marker was useful. METHODS:Serum CEA was measured preoperatively in 1,263 patients who underwent curative resection for colorectal cancer at 3-month intervals for the...

journal_title：Annals of surgical oncology

authors： Park IJ,Choi GS,Lim KH,Kang BM,Jun SH

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Chemotherapy is increasingly used before hepatic resection, with controversial impact regarding liver function. This study aimed to assess the capacity of 99mTc-labelled-mebrofenin SPECT-hepatobiliary scintigraphy (HBS) to predict liver dysfunction due to chemotherapy and/or chemotherapeutic-associated liver...

journal_title：Annals of surgical oncology

authors： Truant S,Baillet C,Gnemmi V,Fulbert M,Turpin A,Dardenne S,Leteurtre E,El Amrani M,Dharancy S,Dubuquoy L,Huglo D,Chesné C,Pruvot FR

更新日期：2020-08-24 00:00:00

abstract：BACKGROUND:Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemoperfusion (HIPEC) is routinely used to treat certain peritoneal carcinomatoses (PC), but it can be associated with relatively high complication rates, prolonged hospital length of stay, and potential mortality. Our objective was to determine ...

journal_title：Annals of surgical oncology

authors： Polanco PM,Ding Y,Knox JM,Ramalingam L,Jones H,Hogg ME,Zureikat AH,Holtzman MP,Pingpank J,Ahrendt S,Zeh HJ,Bartlett DL,Choudry HA

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:We prospectively evaluated the effectiveness of major surgery in treating symptoms of advanced malignancies. METHODS:Fifty-nine patients were evaluated for major symptoms of intent to treat and were followed up until death or last clinical evaluation. Surgeons identified planned operations before surgery as...

journal_title：Annals of surgical oncology

authors： McCahill LE,Smith DD,Borneman T,Juarez G,Cullinane C,Chu DZ,Ferrell BR,Wagman LD

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:AT-rich interactive domain 3A (ARID3A) is a member of the ARID family of DNA-binding proteins. Previous reports have shown that ARID3A controls cell growth in a p53-dependent manner. Recently, it has been reported that expression of the ARID3A protein was markedly increased in colon cancer tissue compared wi...

journal_title：Annals of surgical oncology

authors： Song M,Kim H,Kim WK,Hong SP,Lee C,Kim H

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to assess the quality of care in patients who underwent sentinel lymph node (SLN) mapping for endometrial and cervical cancer staging, and evaluate the impact of different techniques on patient satisfaction, i.e. radiotracer Tc99m versus indocyanine green (ICG) or methylene blue...

journal_title：Annals of surgical oncology

authors： Buda A,Elisei F,Palazzi S,De Ponti E,Arosio M,Vecchione F,Dell'Anna T,Cuzzocrea M,Bussi B,Giuliani D,Di Martino G,Crivellaro C

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Sentinel node biopsy (SNB) is commonly performed in contemporary melanoma management, however there is a paucity of long-term quality of life (QoL) estimates required for economic evaluation of this treatment. METHODS:A single-center, prospective, cross-sectional study of adults with American Joint Committe...

journal_title：Annals of surgical oncology

authors： Morton RL,Tran A,Vessey JY,Rowbotham N,Winstanley J,Shannon K,Spillane AJ,Stretch J,Thompson JF,Saw RP

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Intraperitoneal chemotherapy has an established role in the treatment of selected patients with colorectal peritoneal metastases. Oxaliplatin is highly suitable as a chemotherapeutic agent for hyperthermic intraperitoneal chemotherapy (HIPEC), but its use to date has been limited because of the morbidity cau...

journal_title：Annals of surgical oncology

authors： Mehta AM,Huitema AD,Burger JW,Brandt-Kerkhof AR,van den Heuvel SF,Verwaal VJ

更新日期：2017-04-01 00:00:00