Abstract:
OBJECTIVE:The aim of this study was to evaluate the introduction of diagnostic laparoscopy (DLS) in patients with colorectal peritoneal metastases (PM) to prevent non-therapeutic laparotomies during cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS + HIPEC). METHODS:Patients with histologically proven colorectal PM who underwent a laparotomy for potential CRS + HIPEC from January 2006 to January 2019 were retrospectively identified from a prospectively maintained database. In 2012, DLS was introduced in the preoperative work-up for CRS + HIPEC in our academic center. The rates of non-therapeutic laparotomies, major postoperative complications (Clavien-Dindo grade III or higher), and survival outcomes were investigated for patients who underwent a laparotomy before (cohort A) and after (cohort B) the introduction of DLS. In cohort B, the reasons to refrain from DLS were retrospectively explored from medical records. RESULTS:Overall, 172 patients were included [cohort A: 48 patients (27.9%); cohort B: 124 patients (72.1%)]. A significant drop in the rate of non-therapeutic laparotomies occurred in cohort B compared with cohort A (21.0 vs. 35.4%: p = 0.044), despite only 85 patients (68.5%) from cohort B undergoing DLS in our academic center. The most important reason to refrain from DLS was a recently performed DLS or laparotomy in the referring hospital (48.7%). Major postoperative complications, in-hospital mortality, and survival outcomes were similar for both cohorts. CONCLUSIONS:Performing DLS during the preoperative work-up for CRS + HIPEC prevents non-therapeutic laparotomies in patients with colorectal PM. We recommend performing this laparoscopic screening in an experienced HIPEC center.
journal_name
Ann Surg Oncoljournal_title
Annals of surgical oncologyauthors
Hentzen JEKR,Constansia RDN,Been LB,Hoogwater FJH,van Ginkel RJ,van Dam GM,Hemmer PHJ,Kruijff Sdoi
10.1245/s10434-019-07957-wsubject
Has Abstractpub_date
2020-04-01 00:00:00pages
1084-1093issue
4eissn
1068-9265issn
1534-4681pii
10.1245/s10434-019-07957-wjournal_volume
27pub_type
杂志文章abstract:BACKGROUND:Inflammatory breast cancer (IBC) is an aggressive disease that is treated with trimodality therapy consisting of neoadjuvant chemotherapy, surgery, and post-mastectomy radiation therapy (PMRT). Traditionally, modified radical mastectomy without reconstruction has been the operation of choice for patients wit...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-016-5554-z
更新日期:2016-12-01 00:00:00
abstract:INTRODUCTION:Regional lymph node metastasis is an important prognostic factor for patients with gastric cancer. Occult tumour cells (OTCs), including either micrometastases (MMs) or isolated tumour cells (ITCs), may be a key factor in the development of cancer recurrence in pN0 patients. AIMS:We aimed to determine the...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-020-08524-4
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Patients with borderline resectable pancreatic ductal adenocarcinoma (PDA) represent a high-risk group of patients due to tumor or patient-related characteristics. The optimal management of these patients has not been fully defined. MATERIALS AND METHODS:All patients undergoing evaluation for PDA between 20...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-010-1456-7
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:It is still controversial whether tumor size (Ts) should be considered an important indicator for evaluation the prognosis of gastric cancer (GC). The purpose of this study was to elucidate the prognostic prediction superiority of Ts in the large-scale cohort of GC patients. METHODS:Data from 1,521 patients...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-014-4014-x
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Resection of melanoma metastatic to the liver remains controversial. We evaluated the efficacy of hepatic resection in patients with metastatic ocular and cutaneous melanoma and assessed factors that could affect survival after resection. METHODS:Forty patients with hepatic melanoma metastasis underwent res...
journal_title:Annals of surgical oncology
pub_type: 杂志文章,多中心研究
doi:10.1245/ASO.2006.01.016
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:The association between chemotherapy-induced ovarian dysfunction (CIOD) and response to neoadjuvant chemotherapy (NAC) is not known. We therefore investigated the impact of CIOD on response to NAC in breast cancer patients according to estrogen receptor (ER) status. METHODS:In total, 343 premenopausal breas...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-015-4806-7
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Recent population-based studies have highlighted a disproportionate increase in the incidence of rectal cancer among adults younger than aged 50 years. To determine whether different intervention and surveillance strategies might be needed for younger patients, the patterns of care and oncologic outcomes amo...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-011-1674-7
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:We sought to identify genes associated with the progression and metastasis of esophageal squamous-cell cancer by comparing the expression profiles of normal, primary cancer, and metastatic cancer cells isolated with laser microdissection. METHODS:Oligo microarray analysis identified several lymph node-speci...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-010-1271-1
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the usefulness of shear wave elastography (SWE) for predicting cervical lymph node (LN) metastasis and the prognostic implication of SWE as histopathologic factors of papillary thyroid carcinoma (PTC). METHODS:Eighty-four LNs of 66 patients with PTC underwent B-mode ultras...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-014-3627-4
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Extending the original criteria of the Chemoradiotherapy for Oesophageal Cancer followed by Surgery Study (CROSS) in daily practice may increase the treatment outcome of esophageal cancer (EC) patients. This retrospective national cohort study assessed the impact on the pathologic complete response (pCR) rat...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
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更新日期:2020-11-28 00:00:00
abstract:BACKGROUND:Cryotherapy is a method of in situ destruction of tumors by freeze/thaw mechanisms. Cancer cells located in the peripheral zone of the tumor undergoing cryotherapy can die by apoptosis. We hypothesized that p21WAF1 is involved in the mediation of cryotherapy-induced apoptosis. METHODS:HT29 cells grown on a ...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/ASO.2005.11.021
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:We hypothesized that metastasis beyond the sentinel lymph nodes (SLN) to the nonsentinel nodes (NSN) is an important predictor of survival. MATERIALS AND METHODS:Analysis was performed of a prospective multi-institutional study that included patients with melanoma ≥ 1.0 mm in Breslow thickness. All patients...
journal_title:Annals of surgical oncology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1245/s10434-010-1208-8
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Detection of cancer micrometastases is required for improvement of cancer therapy. The aim of this study was to establish a rapid and practical genetic assay to detect micrometastasis in gastric cancer and to assess its clinical significance with respect to prognosis. METHODS:A novel RNA amplification syste...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/ASO.2004.12.043
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Sarcopenia is recognized as an important prognostic factor in various types of cancer, including gastric cancer. While long-term survival analyses typically focus on overall and disease-specific survival, death from other causes has received far less attention. METHODS:We reviewed medical records of 491 gas...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-018-6354-4
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Thick (>or=4-mm) primary melanomas are believed to be associated with a high incidence of occult distant metastases. The use of sentinel lymph node (SLN) mapping and biopsy in the treatment lesions has been questioned. METHODS:A retrospective review of a computerized database identified 114 patients who und...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/aso.2003.03.055
更新日期:2003-05-01 00:00:00
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journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-016-5542-3
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:The main goal of the current study was to compare survival differences among subgroups of primary ovarian cancer patients in International Federation of Gynecology and Obstetrics (FIGO) stages IIIC and IIIA1 after complete tumor debulking surgery. METHODS:A total of 218 patients with primary ovarian cancer w...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-015-4959-4
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Hyperthermic intraperitoneal chemotherapy (HIPEC) following cytoreductive surgery is a radical but effective treatment option for patients with peritoneal carcinomatosis (PC). Unfortunately, a standardized HIPEC protocol is missing impeding systematic comparisons with regard to minimal effective temperatures...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-015-4853-0
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Although the honeycomb microcystic type is common and typical for a serous cystic tumor (SCT), clinical and radiological features are diverse. Systematic classification of SCT subtypes is not well established. The purpose of this study was to classify the subtypes of SCT and to clarify its clinical and patho...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-008-9959-1
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Persistent or recurrent primary hyperparathyroidism (1 degrees HPTH) is ideally treated with limited dissection, based on accurate localization, to minimize operative risks. To accurately localize parathyroid tissue, we employed ultrasound-guided fine needle aspiration (US FNA) with an on-site rapid parathyr...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-006-9180-z
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Hospital attributes have been shown to impact short- and long-term outcomes after cancer surgery. However, the effect of hospital attributes on processes of cancer care in terms of delivery of guideline recommended care has not been evaluated. We examined the impact of hospital attributes (volume and type) o...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-011-1973-z
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:We performed robot-assisted neck dissection (RAND) via a modified face-lift (MFLA) or retroauricular approach for neck management and carried out free flap reconstruction via these approaches in patients with head and neck cancer. We assessed the feasibility of free flap reconstruction in patients who had un...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
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更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:A suitable treatment strategy for esophageal cancer after definitive chemoradiotherapy for T4 cases has not been established and remains unclear. This study aimed to clarify the independent prognostic factors, surgical indications, and optimal extent of lymphadenectomy for T4 esophageal cancer. METHODS:Of 8...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-018-7074-5
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:The keystone flap is being promoted as an advance in oncological surgical reconstruction. Wound closure with this island flap involves two V-Y advancements toward the center and along the long axis of the island, at right angles to the line of maximum tension when the wound is closed. It is implied that the ...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
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更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:The usefulness of enteral nutrition via a nasointestinal tube for patients who develop postoperative pancreatic fistula (POPF) after miscellaneous pancreatectomy procedures has been reported. However, no clear evidence regarding whether oral intake is possible during management of POPF after pancreatoduodene...
journal_title:Annals of surgical oncology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Recently, ultrasound (US)-guided needle biopsy has been proposed as an acceptable alternative to open biopsy in women with nonpalpable breast masses. This study evaluated the accuracy of US-guided needle biopsy of nonpalpable breast masses performed by surgeons at the time of the initial clinical examination...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1007/BF02305766
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:Sentinel lymph node (SLN) mapping techniques have been validated in breast cancer and melanoma. This study summarizes our experience with SLN mapping for colon cancer. METHODS:Fifty-five patients with colon cancer underwent intraoperative SLN mapping. One mL of 1% isosulfan blue was injected subserosally ar...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1007/BF02573890
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:Age of patients with melanoma varies directly with mortality and inversely with the presence of sentinel lymph node (SLN) metastasis. To gain further insight into this apparent paradox, we analyzed the relationship between age and other major prognostic factors. METHODS:The Sunbelt Melanoma Trial is a prosp...
journal_title:Annals of surgical oncology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1245/aso.2004.04.015
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:Cancer registries have been set up worldwide to provide information for cancer health planning. There are known variations in breast cancer incidence and mortality worldwide. However, breast cancer incidence, pathological characteristics, and survival data is still under-reported in Asian countries. This is ...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-011-1960-4
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:This study was designed to identify the prevalence of BRAF mutations in Chinese patients with lung adenocarcinoma, and to reveal the association between BRAF mutations and clinicopathological characteristics in these patients. METHODS:From October 2007 to February 2013, patients with newly diagnosed primary...
journal_title:Annals of surgical oncology
pub_type: 杂志文章
doi:10.1245/s10434-015-4640-y
更新日期:2015-12-01 00:00:00