Predictors of regional nodal disease in patients with thin melanomas.

Abstract:

BACKGROUND:Most melanoma patients present with thin (0, vertical growth phase (VGP), male sex, and ulceration were statistically significant predictors of RND. Patients at the highest risk according to a classification tree analysis (VGP and MR>0) had an RND rate of 11.9%. The regression model developed predicted well the SLN status in the validation sample. CONCLUSIONS:Investigation of a large pre-SLN population identified MR>0, ulceration, VGP, and male sex as independently predictive of RND in patients with thin melanomas. These factors may help to identify subgroups of these patients that have clinically significant risks of SLN positivity.

journal_name

Ann Surg Oncol

authors

Karakousis GC,Gimotty PA,Botbyl JD,Kesmodel SB,Elder DE,Elenitsas R,Ming ME,Guerry D,Fraker DL,Czerniecki BJ,Spitz FR

doi

10.1245/ASO.2006.05.011

keywords:

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

533-41

issue

4

eissn

1068-9265

issn

1534-4681

journal_volume

13

pub_type

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