Suppression of beta-catenin by antisense oligomers augments tumor response to isolated limb perfusion in a rodent model of adenomatous polyposis coli-mutant colon cancer.

abstract：BACKGROUND:Age of patients with melanoma varies directly with mortality and inversely with the presence of sentinel lymph node (SLN) metastasis. To gain further insight into this apparent paradox, we analyzed the relationship between age and other major prognostic factors. METHODS:The Sunbelt Melanoma Trial is a prosp...

journal_title：Annals of surgical oncology

authors： Chao C,Martin RC 2nd,Ross MI,Reintgen DS,Edwards MJ,Noyes RD,Hagendoorn LJ,Stromberg AJ,McMasters KM

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:An oncolytic herpes simplex virus type 1 mutant (HF10) has been isolated and evaluated for antitumor efficacy in a syngeneic immunocompetent mouse model, where it was effective against cancer and conferred resistance to rechallenge with tumor cells in all surviving mice. Several studies have shown that HF10 ...

journal_title：Annals of surgical oncology

authors： Kimata H,Imai T,Kikumori T,Teshigahara O,Nagasaka T,Goshima F,Nishiyama Y,Nakao A

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Despite advances in the treatment of patients with gastric cancer, the debate over the optimal extent of lymphadenectomy continues. METHOD:A review of the classification, rationale for, and boundaries of lymphadenectomy is presented. A review of the available literature comparing D1 versus D2 versus D3 lymp...

journal_title：Annals of surgical oncology

authors： Mogal H,Fields R,Maithel SK,Votanopoulos K

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Laparoscopic pancreaticoduodenectomy with venous reconstruction is not commonly performed due to its technical challenges. In this video, we focus on the technical aspects for how to perform this procedure safely. METHODS:In a 69-year-old female with jaundice and diarrhea, a computed tomography scan showed ...

journal_title：Annals of surgical oncology

authors： Garbarino GM,Fuks D,Cowan J,Ward M,Moisan F,Donatelli G,Beaussier M,Gayet B

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The association between chemotherapy-induced ovarian dysfunction (CIOD) and response to neoadjuvant chemotherapy (NAC) is not known. We therefore investigated the impact of CIOD on response to NAC in breast cancer patients according to estrogen receptor (ER) status. METHODS:In total, 343 premenopausal breas...

journal_title：Annals of surgical oncology

authors： Ahn SK,Lee HB,Han W,Moon HG,You JM,Kim J,Han SW,Im SA,Kim TY,Noh DY

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Malignant ascites (MA) is a distressing problem usually managed by repeated paracenteses. Paracentesis represents a meaningful time point in identifying patients with a specific presentation. OBJECTIVE:The objective of this study is to examine symptom clustering in MA patients at paracentesis. METHODS:Pre-...

journal_title：Annals of surgical oncology

authors： Husain A,Bezjak A,Easson A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:The efficacy of chemoprevention for breast cancer risk reduction has been demonstrated in randomized controlled trials; however, use remains low. We sought to determine whether uptake differed by risk factors, and to identify reasons for refusal and termination. METHODS:Women seen in a high-risk c...

journal_title：Annals of surgical oncology

authors： Flanagan MR,Zabor EC,Stempel M,Mangino DA,Morrow M,Pilewskie ML

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:A positive circumferential radial margin (CRM) after rectal cancer surgery is an important predictor of local recurrence. The definition of a positive CRM differs internationally, and reported rates vary greatly in the literature. This study used time-series population-based data to assess positive CRM rates...

journal_title：Annals of surgical oncology

authors： Keng C,Coates A,Grubac V,Lovrics P,DeNardi F,Thabane L,Simunovic M

更新日期：2016-02-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Takamori S,Toyokawa G

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Reduced port laparoscopic surgery (RPLS), as a more minimally invasive treatment alternative to conventional laparoscopic surgery (CLS), has been increasing in recent years. 1 With the accumulation of surgical experience and improvements in surgical techniques, the indication of RPLS has been gradually exten...

journal_title：Annals of surgical oncology

authors： Lin T,Mou TY,Hu YF,Liu H,Li TJ,Lu YM,Yu J,Li GX

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:RAD18 plays an important role in DNA damage repair by inducing monoubiquitinated PCNA (mUB-PCNA) in both cancer and normal tissues. Previous studies have not determined the significance of RAD18 expression in clinical gastric cancer (GC) samples. Thus, this study aimed to clarify the expression and functiona...

journal_title：Annals of surgical oncology

authors： Baatar S,Bai T,Yokobori T,Gombodorj N,Nakazawa N,Ubukata Y,Kimura A,Kogure N,Sano A,Sohda M,Sakai M,Tumenjargal A,Ogata K,Kuwano H,Shirabe K,Saeki H

更新日期：2020-10-01 00:00:00

abstract：:Intraoperative radiotherapy (IORT) is increasingly used worldwide. Breast cancer is the most rapidly growing indication for IORT, approaching 70-80% of cases in most centers. This report reviews the theoretical background and clinical use of IORT for primary and metastasized breast cancer. There are established applic...

journal_title：Annals of surgical oncology

authors： Wenz F

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Peritoneal carcinomatosis (PC), which has hitherto been regarded as a lethal entity, can now be cured with surgery (treating macroscopic tumor seeding) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) (treating residual microscopic disease). The purpose of this study was to analyze the morbidi...

journal_title：Annals of surgical oncology

authors： Elias D,Goere D,Blot F,Billard V,Pocard M,Kohneh-Shahri N,Raynard B

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Currently, cytoreductive surgery and hyperthermic intraperitoneal chemotherapy are accepted treatments for surgically resectable appendiceal epithelial neoplasms. However, for nonsurgical candidates, systemic treatment may be considered. The purpose of this analysis was to determine the benefit of biologic t...

journal_title：Annals of surgical oncology

authors： Choe JH,Overman MJ,Fournier KF,Royal RE,Ohinata A,Rafeeq S,Beaty K,Phillips JK,Wolff RA,Mansfield PF,Eng C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Radical gastrectomy is the cornerstone of the treatment of locally advanced gastric cancer. This study was designed to evaluate factors associated with a tumor-positive resection margin after gastrectomy and to evaluate the influence of hospital volume. METHODS:In this Dutch cohort study, patients with junc...

journal_title：Annals of surgical oncology

authors： van der Werf LR,Cords C,Arntz I,Belt EJT,Cherepanin IM,Coene PLO,van der Harst E,Heisterkamp J,Langenhoff BS,Lamme B,van Berge Henegouwen MI,Lagarde SM,Wijnhoven BPL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Patients with periampullary cancer frequently suffer obstructive jaundice and commonly require preoperative biliary drainage (PBD) for relief and to avoid related complications. Although research has established a correlation between PBD and surgical wound infection, the impact of PBD on major infectious com...

journal_title：Annals of surgical oncology

authors： Wu JM,Ho TW,Yen HH,Wu CH,Kuo TC,Yang CY,Tien YW

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Currently, reinterventions for involved margins after breast-conserving surgery remain common. The aim of this study was to assess the capability of the cavity shave margins (CSM) technique to reduce positive margin rates and reoperations compared with simple lumpectomy (SL). The impact of CSM on the various...

journal_title：Annals of surgical oncology

authors： Corsi F,Sorrentino L,Bonzini M,Bossi D,Truffi M,Amadori R,Nebuloni M,Brillat B,Mazzucchelli S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:It has been proposed that clones of tumor cells acquire higher metastatic potential as a result of specific genetic alterations. This study was designed to determine the role of the c-met protooncogene in systemic spread by comparing the loss of the c-met protooncogene between primary and metastatic breast c...

journal_title：Annals of surgical oncology

authors： Ng EH,Pey HB,Law HY,Ng I,Ji CY,Lin V,Soo KC

更新日期：1997-09-01 00:00:00

abstract：INTRODUCTION:Lymphatic drainage patterns from the breast have been described in the past. Drainage may change after treatment of a breast or axilla, and this may have implications for lymphatic mapping. The aim of this study was to determine the lymphatic drainage patterns in breast cancer patients with a previously tr...

journal_title：Annals of surgical oncology

authors： van der Ploeg IM,Oldenburg HS,Rutgers EJ,Baas-Vrancken Peeters MJ,Kroon BB,Valdés Olmos RA,Nieweg OE

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:Our study aims to determine whether patients with lobular-type breast cancer have significantly improved rates of breast conservation (BCT) after neoadjuvant chemotherapy (nCT). METHODS:Patients who received nCT and surgery within three prospective trials between 1995 and 2007 at the Medical University of...

journal_title：Annals of surgical oncology

authors： Fitzal F,Mittlboeck M,Steger G,Bartsch R,Rudas M,Dubsky P,Riedl O,Jakesz R,Gnant M

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:CD44, a cancer stem cell surface marker, is associated with treatment resistance and prognosis in some cancers. In the present study, we examined the predictive value of CD44 in muscle-invasive bladder cancer (MIBC). METHODS:We retrospectively analyzed the clinical outcomes of 105 MIBC patients and correlat...

journal_title：Annals of surgical oncology

authors： Wu CT,Lin WY,Chen WC,Chen MF

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:mTHPC-mediated photodynamic therapy (PDT) is used for treatment of early head and neck squamous cell carcinoma. This study is a retrospective comparison of PDT with transoral surgery in the treatment of early primary squamous cell carcinoma of the oral cavity/oropharynx. METHODS:PDT data were retrieved from...

journal_title：Annals of surgical oncology

authors： de Visscher SA,Melchers LJ,Dijkstra PU,Karakullukcu B,Tan IB,Hopper C,Roodenburg JL,Witjes MJ

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Patients with palpable melanoma groin metastases have a poor prognosis. There is debate whether a combined superficial and deep groin dissection (CGD) is necessary or if superficial groin dissection (SGD) alone is sufficient. AIM:The aim of this study was to analyze risk factors for deep pelvic nodal involv...

journal_title：Annals of surgical oncology

authors： Oude Ophuis CM,van Akkooi AC,Hoekstra HJ,Bonenkamp JJ,van Wissen J,Niebling MG,de Wilt JH,van der Hiel B,van de Wiel B,Koljenović S,Grünhagen DJ,Verhoef C

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:This prospective multicenter sentinel lymph node (SLN) trial investigated whether molecular analysis would improve the detection of SLN metastases and their prognostic value. We report mammaglobin quantitative real-time polymerase chain reaction (qRT-PCR) results and clinical outcome for 547 patients (mean f...

journal_title：Annals of surgical oncology

authors： Verbanac KM,Min CJ,Mannie AE,Lu J,O'Brien KF,Rosman M,Tafra L,ECU\/AAMC Sentinel Node Study Group.

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Carefully selected patients with noncolorectal, nonneuroendocrine (NCNN) liver metastases may benefit from hepatic resection. The incidence of occult unresectable disease and the possible benefits of staging laparoscopy in these patients are not known. METHODS:From December 1997 to July 2000, staging laparo...

journal_title：Annals of surgical oncology

authors： D'Angelica M,Jarnagin W,Dematteo R,Conlon K,Blumgart LH,Fong Y

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Resectability rates for extrahepatic cholangiocarcinoma have increased over time, but long-term survival after resection alone with curative intent remains poor. Recent series suggest improved survival with adjuvant therapy. Patient subsets benefiting most from adjuvant therapy have not been clearly defined....

journal_title：Annals of surgical oncology

authors： Ecker BL,Vining CC,Roses RE,Maggino L,Lee MK,Drebin JA,Fraker DL,Vollmer CM Jr,Datta J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The LAP07 randomized trial calls into question the role of radiation therapy (RT) in the modern treatment of locally advanced pancreatic cancer (LAPC). However, advances in chemotherapy and RT limit application of the LAP07 results to current clinical practice. Here we utilize the National Cancer Database (N...

journal_title：Annals of surgical oncology

authors： Zhong J,Switchenko J,Behera M,Kooby D,Maithel SK,McDonald MW,Lin JY,Cassidy RJ,El-Rayes B,Landry J,Patel PR

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:According to the revised staging of the American Joint Committee on Cancer, 8th edition (AJCC8), the N category in pancreatic ductal adenocarcinoma is classified as N0 (0), N1 (1-3), and N2 (≥ 4) based on the number of metastatic lymph nodes (LNs). This study aimed to validate this classification and analyze...

journal_title：Annals of surgical oncology

authors： Asano D,Nara S,Kishi Y,Esaki M,Hiraoka N,Tanabe M,Shimada K

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The role of postmastectomy radiotherapy (PMRT) in breast cancer patients receiving neoadjuvant chemotherapy (NAC) is controversial. We aimed to evaluate the effectiveness of radiotherapy in patients treated with NAC and mastectomy in the Japanese Breast Cancer Registry. METHODS:We enrolled patients who rece...

journal_title：Annals of surgical oncology

authors： Miyashita M,Niikura N,Kumamaru H,Miyata H,Iwamoto T,Kawai M,Anan K,Hayashi N,Aogi K,Ishida T,Masuoka H,Iijima K,Masuda S,Tsugawa K,Kinoshita T,Tsuda H,Nakamura S,Tokuda Y

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:This anatomic study details the lymphatic drainage of the upper extremity (UE) and breast, as well as its course in the axilla and its relation to axillary reverse mapping. Two aspects important for breast cancer surgery were followed: connection between the lymphatics of the UE and breast, and the possible ...

journal_title：Annals of surgical oncology

authors： Pavlista D,Eliska O

更新日期：2012-10-01 00:00:00