Chemotherapy with or Without Definitive Radiation Therapy in Inoperable Pancreatic Cancer.

abstract：BACKGROUND:The role of supplemental oxygen therapy in the healing of esophagojejunal anastomosis is still very much in an experimental stage. The aim of the present prospective, randomized study was to assess the effect of administration of perioperative supplemental oxygen therapy on esophagojejunal anastomosis, where...

journal_title：Annals of surgical oncology

authors： Schietroma M,Cecilia EM,Carlei F,Sista F,De Santis G,Piccione F,Amicucci G

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Initial therapy for early hepatocellular carcinoma (HCC) with well-compensated cirrhosis is controversial. While we previously reported on the effect of clinical factors and surgeon specialty on choice of therapy for early HCC, other nonclinical factors also may impact decision-making. METHODS:Surgeons who ...

journal_title：Annals of surgical oncology

authors： Nathan H,Segev DL,Bridges JF,Massie AB,Cameron AM,Hirose K,Schulick RD,Choti MA,Pawlik TM

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Heated intraoperative intraperitoneal chemotherapy achieves high peritoneal concentrations with limited systemic absorption and has become an important tool in the management of patients with peritoneal carcinomatosis from low-grade malignancies such as pseudomyxoma peritonei and in selected cases of high-gr...

journal_title：Annals of surgical oncology

authors： Esquivel J,Angulo F,Bland RK,Stephens AD,Sugarbaker PH

更新日期：2000-05-01 00:00:00

abstract：PURPOSE:To analyze the relationship between the size of metastatic sentinel lymph nodes (SLNs) and the risk of non-sentinel lymph node (non-SLN) metastasis in endometrial cancer. PATIENTS AND METHODS:From a total of 328 patients with endometrial cancer who underwent SLN mapping from January 2013 to April 2019, 142 pat...

journal_title：Annals of surgical oncology

authors： Baiocchi G,Mantoan H,Gonçalves BT,Faloppa CC,Kumagai LY,Badiglian-Filho L,da Costa AABA,De Brot L

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:For multifocal hepatocellular carcinomas (HCCs) that are untreatable with resection only, locoregional therapies added to hepatectomy have been introduced. However, some preliminary reports have documented average survival results and relatively high complication rates. We evaluated the long-term survival re...

journal_title：Annals of surgical oncology

authors： Choi D,Lim HK,Joh JW,Kim SJ,Kim MJ,Rhim H,Kim YS,Yoo BC,Paik SW,Park CK

更新日期：2007-12-01 00:00:00

abstract：:The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of colorectal cancer specifically as it relates to the management of peritoneal surface malignancy. These guidelines are developed with input from leading experts including surgical oncologists, medical oncologists, patho...

journal_title：Annals of surgical oncology

authors： Chicago Consensus Working Group.

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Adaptor proteins, with multimodular structures, can participate in the regulation of various cellular functions. A novel adaptor protein XB130 has been implicated as a substrate and regulator of tyrosine kinase-mediated signaling and in controlling cell proliferation and apoptosis in thyroid and lung cancer ...

journal_title：Annals of surgical oncology

authors： Shiozaki A,Kosuga T,Ichikawa D,Komatsu S,Fujiwara H,Okamoto K,Iitaka D,Nakashima S,Shimizu H,Ishimoto T,Kitagawa M,Nakou Y,Kishimoto M,Liu M,Otsuji E

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:The time interval between CRT and surgery in rectal cancer patients is still the subject of debate. The aim of this study was to first evaluate the nationwide use of restaging magnetic resonance imaging (MRI) and its impact on timing of surgery, and, second, to evaluate the impact of timing of surgery after ...

journal_title：Annals of surgical oncology

authors： Detering R,Borstlap WAA,Broeders L,Hermus L,Marijnen CAM,Beets-Tan RGH,Bemelman WA,van Westreenen HL,Tanis PJ,Dutch Snapshot Research Group.

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate whether patient satisfaction, as measured by the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey, is associated with short-term outcomes after major cancer surgery. MATERIALS AND METHODS:We first used national Medicare claims to identi...

journal_title：Annals of surgical oncology

authors： Kaye DR,Richardson CR,Ye Z,Herrel LA,Ellimoottil C,Miller DC

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Survival for positive sentinel lymph node (SLN) patients does not differ between completion lymph node dissection (CLND) and nodal observation (OBS). However, treating these patients with CLND and checkpoint inhibitors, such as pembrolizumab (PEM), improves outcomes. This study evaluated the cost-effectivene...

journal_title：Annals of surgical oncology

authors： Standage H,Hersh AR,Caughey A,Taylor M,Vetto J,Han D

更新日期：2020-09-19 00:00:00

abstract：BACKGROUND:The use of immunotherapeutic agents, specifically immune checkpoint inhibitors (ICIs) for solid malignancies, is rapidly rising, and many new agents and treatment combinations are in development. However, ICIs have a unique side-effect profile of immune-related adverse events (irAEs) compared with chemothera...

journal_title：Annals of surgical oncology

authors： Helmink BA,Roland CL,Kiernan CM,Wargo JA

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the introduction of diagnostic laparoscopy (DLS) in patients with colorectal peritoneal metastases (PM) to prevent non-therapeutic laparotomies during cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS + HIPEC). METHODS:Patients with histologically...

journal_title：Annals of surgical oncology

authors： Hentzen JEKR,Constansia RDN,Been LB,Hoogwater FJH,van Ginkel RJ,van Dam GM,Hemmer PHJ,Kruijff S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Patients with palpable melanoma groin metastases have a poor prognosis. There is debate whether a combined superficial and deep groin dissection (CGD) is necessary or if superficial groin dissection (SGD) alone is sufficient. AIM:The aim of this study was to analyze risk factors for deep pelvic nodal involv...

journal_title：Annals of surgical oncology

authors： Oude Ophuis CM,van Akkooi AC,Hoekstra HJ,Bonenkamp JJ,van Wissen J,Niebling MG,de Wilt JH,van der Hiel B,van de Wiel B,Koljenović S,Grünhagen DJ,Verhoef C

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:When pathological diagnosis following endoscopic resection (ER) for early gastric cancer (EGC) suggests probable lymph node metastasis, additional surgery with lymphadenectomy should be performed. The sentinel node (SN) concept has yet to be applied to tumors following ER. The aim of this study was to evalua...

journal_title：Annals of surgical oncology

authors： Mayanagi S,Takeuchi H,Kamiya S,Niihara M,Nakamura R,Takahashi T,Wada N,Kawakubo H,Saikawa Y,Omori T,Nakahara T,Mukai M,Kitagawa Y

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:We provide a statistical analysis of the learning phase for sentinel node biopsy. METHODS:Four learning phases were analyzed: 25, 50, 75, and 150 procedures with a corresponding number of 10, 20, 30, and 60 tumor-positive cases. Critical values of nonidentification rate and false-negative rate were defined....

journal_title：Annals of surgical oncology

authors： Tanis PJ,Nieweg OE,Hart AA,Kroon BB

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Histologic grade, TNM stage, and Nottingham Prognostic Index are traditional prognostic tools for breast cancer. "IHC-molecular" classification of breast cancer can also identify patients at different recurrence risks and provides insight into cancer therapy. However, cancers in each group are heterogeneous....

journal_title：Annals of surgical oncology

authors： Ni YB,Tsang JY,Chan SK,Tse GM

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:NIMA-related kinase 2 (NEK2), an enzyme involved in the development and progression of cancer, is abnormally expressed in a wide variety of human cancers, including colorectal cancer (CRC), and is known to have roles in cell division and mitotic regulation through centrosome splitting. We investigated the cl...

journal_title：Annals of surgical oncology

authors： Takahashi Y,Iwaya T,Sawada G,Kurashige J,Matsumura T,Uchi R,Ueo H,Takano Y,Eguchi H,Sudo T,Sugimachi K,Yamamoto H,Doki Y,Mori M,Mimori K

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Recently, the American Joint Committee on Cancer (AJCC) 7th edition proposed new response criteria for neoadjuvant chemotherapy (NAC) in breast cancer. The purpose of this study was to evaluate the clinical usefulness of AJCC response criteria. METHODS:A total of 398 consecutive stage II or III breast cancer p...

journal_title：Annals of surgical oncology

authors： Keam B,Im SA,Lim Y,Han SW,Moon HG,Oh DY,Cho N,Lee SH,Han W,Moon WK,Kim DW,Kim TY,Park IA,Noh DY

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:In several neoplastic diseases, including breast cancer, immunosuppression correlates with disease stage, progression, and outcome. Thus, thorough analysis of immune parameters in breast cancer patients may be beneficial in designing effective anticancer immune-based therapies. METHODS:We investigated dendr...

journal_title：Annals of surgical oncology

authors： Pockaj BA,Basu GD,Pathangey LB,Gray RJ,Hernandez JL,Gendler SJ,Mukherjee P

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:During the breast lumpectomy procedure, surgeons traditionally elect to use either a superficial or full-thickness closure when sealing the wound depending on surgeon preference as well as desired outcomes. The purpose of this study was to examine dosimetric endpoints in patients with superficial versus full...

journal_title：Annals of surgical oncology

authors： Shaikh T,Narra V,Goyal S,Ahlawat S,Kirstein L,Kearney T,Haffty BG,Khan AJ

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Modified Appleby procedure could be indicated in stage III locally advanced body pancreatic ductal adenocarcinoma (PDAC) involving the celiac axis after neoadjuvant treatment. PATIENTS AND METHODS:We report the case of a 38-year-old woman presenting a tumor arising from the body of the pancreas, involving t...

journal_title：Annals of surgical oncology

authors： Triki H,Bergeat D,Bougard M,Robin F,Sulpice L

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:In a Dutch phase II trial conducted between 2006 and 2010, short-course radiotherapy followed by systemic therapy with capecitabine, oxaliplatin, and bevacizumab as neoadjuvant treatment and subsequent radical surgical treatment of primary tumor and metastatic sites was evaluated. In this study, we report th...

journal_title：Annals of surgical oncology

authors： Bisschop C,van Dijk TH,Beukema JC,Jansen RLH,Gelderblom H,de Jong KP,Rutten HJT,van de Velde CJH,Wiggers T,Havenga K,Hospers GAP

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:HER-2/neu (c-erbB-2, HER2) gene amplification and protein overexpression have been associated with poor prognosis in several solid tumors, including breast and gastric cancer. Its incidence and significance in esophageal adenocarcinoma is unknown. MATERIALS AND METHODS:Tissue microarrays were successfully c...

journal_title：Annals of surgical oncology

authors： Thompson SK,Sullivan TR,Davies R,Ruszkiewicz AR

更新日期：2011-07-01 00:00:00

abstract：:The purpose of this study was to determine the outcome of surgery for patients with recurrent gastric or gastroesophageal cancer. We queried records from 7,459 patients who presented with gastric or gastroesophageal cancer to our institution from 1973 through 2005 to identify those for whom resection of recurrent dise...

journal_title：Annals of surgical oncology

authors： Badgwell B,Cormier JN,Xing Y,Yao J,Bose D,Krishnan S,Pisters P,Feig B,Mansfield P

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:This study aimed to determine the relationship between mammographic calcifications and magnetic resonance imaging (MRI) tumoral enhancement before and after neoadjuvant chemotherapy (NAC) and to assess the impact of these findings on surgical management. METHODS:This Institutional Review Board-approved, Hea...

journal_title：Annals of surgical oncology

authors： Feliciano Y,Mamtani A,Morrow M,Stempel MM,Patil S,Jochelson MS

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Tumor growth and metastases require the development of new vessels (angiogenesis). Angiogenesis, assessed by microvessel count using immunocytochemical stain of endothelial cells, has been shown to predict metastases and correlate with early death. Recently developed color Doppler mapping can detect the "tum...

journal_title：Annals of surgical oncology

authors： Lee WJ,Chu JS,Houng SJ,Chung MF,Wang SM,Chen KM

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The prognosis of patients with peritoneally metastasized colorectal cancer has improved significantly with the introduction of cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (CRS + HIPEC). Although a macroscopically complete resection is achieved in nearly every patient, recurren...

journal_title：Annals of surgical oncology

authors： Simkens GA,van Oudheusden TR,Luyer MD,Nienhuijs SW,Nieuwenhuijzen GA,Rutten HJ,de Hingh IH

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Clinical practice guidelines have been developed to improve melanoma patient care. However, it is unclear whether failure to comply with these standards (either excessive or inadequate treatment) increases morbidity or relapse rates. Therefore, we undertook this study to evaluate the effect of variance from ...

journal_title：Annals of surgical oncology

authors： Erickson Foster J,Velasco JM,Hieken TJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:The use of lymphatic mapping (LM) is being investigated to improve the staging of colorectal cancer (CRC) and thereby identify patients who might benefit from adjuvant chemotherapy. This study evaluated in vivo, laparoscopic, and ex vivo approaches for the ultrastaging of CRC. METHODS:Seventy-five CRC patie...

journal_title：Annals of surgical oncology

authors： Wood TF,Saha S,Morton DL,Tsioulias GJ,Rangel D,Hutchinson W Jr,Foshag LJ,Bilchik AJ

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Studies examining differences in presentation of patients with benign [follicular adenoma (FA)] and malignant follicular thyroid neoplasms [follicular thyroid carcinoma (FTC) or follicular variant papillary thyroid carcinoma (FVPTC)] include only one or two of these subtypes, and none has considered clinical...

journal_title：Annals of surgical oncology

authors： Najafian A,Olson MT,Schneider EB,Zeiger MA

更新日期：2015-09-01 00:00:00