Short-Course Radiotherapy Followed by Neoadjuvant Bevacizumab, Capecitabine, and Oxaliplatin and Subsequent Radical Treatment in Primary Stage IV Rectal Cancer: Long-Term Results of a Phase II Study.

abstract：BACKGROUND:Isolated limb perfusion (ILP) results in complete response (CR) rates of 60% to 90% in patients with regionally advanced melanoma. Survival after a CR may be influenced by various factors, particularly out-of-field disease in iliac lymph nodes (ILN) identified during lower-extremity ILP. We examined clinical...

journal_title：Annals of surgical oncology

authors： Zogakis TG,Bartlett DL,Libutti SK,Liewehr DJ,Steinberg SM,Fraker DL,Alexander HR

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Barrett's esophagus (BE) is a premalignant lesion characterized by replacement of normal squamous epithelium with columnar epithelium. This lesion can progress to dysplasia and adenocarcinoma. Recently, the Fas receptor and retinoblastoma (Rb) protein have been described as important mediators of apoptosis a...

journal_title：Annals of surgical oncology

authors： Coppola D,Schreiber RH,Mora L,Dalton W,Karl RC

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Although often proposed as a means to reduce the harmful consequences of tumor spill, water lavage has yet to be systematically evaluated in relevant in vitro and in vivo models. This study evaluates the mechanisms and utility of a single water lavage to improve the sequelae of tumor spill during laparotomy....

journal_title：Annals of surgical oncology

authors： Ito F,Camoriano M,Seshadri M,Evans SS,Kane JM 3rd,Skitzki JJ

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Little is known about complications after major duodenopancreatic surgery for duodenopancreatic neuroendocrine tumors (dpNETs) in multiple endocrine neoplasia type 1 (MEN1). Therefore, the incidence and severity of complications after major surgery for MEN1-related dpNETs were assessed. METHODS:Patients wer...

journal_title：Annals of surgical oncology

authors： van Beek DJ,Nell S,Vorselaars WMCM,Bonsing BA,van Eijck CHJ,van Goor H,Nieveen van Dijkum EJ,Dejong CHC,Valk GD,DutchMEN Study Group (DMSG).,Borel Rinkes IHM,Vriens MR

更新日期：2021-01-31 00:00:00

abstract：BACKGROUND:RAD18 plays an important role in DNA damage repair by inducing monoubiquitinated PCNA (mUB-PCNA) in both cancer and normal tissues. Previous studies have not determined the significance of RAD18 expression in clinical gastric cancer (GC) samples. Thus, this study aimed to clarify the expression and functiona...

journal_title：Annals of surgical oncology

authors： Baatar S,Bai T,Yokobori T,Gombodorj N,Nakazawa N,Ubukata Y,Kimura A,Kogure N,Sano A,Sohda M,Sakai M,Tumenjargal A,Ogata K,Kuwano H,Shirabe K,Saeki H

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Hyperthermic intraperitoneal chemotherapy (HIPEC) following cytoreductive surgery is a radical but effective treatment option for patients with peritoneal carcinomatosis (PC). Unfortunately, a standardized HIPEC protocol is missing impeding systematic comparisons with regard to minimal effective temperatures...

journal_title：Annals of surgical oncology

authors： Schaaf L,van der Kuip H,Zopf W,Winter S,Münch M,Mürdter TE,Thon KP,Steurer W,Aulitzky WE,Ulmer C

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:While previously thought to be clinically indolent, recent data suggest significant late metastatic capacity of solitary fibrous tumors (SFTs). We define prognostic factors for recurrence and disease-specific death (DSD) in resected primary SFTs. METHODS:Resected primary SFTs from 1982 to 2015 were identified ...

journal_title：Annals of surgical oncology

authors： Gholami S,Cassidy MR,Kirane A,Kuk D,Zanchelli B,Antonescu CR,Singer S,Brennan M

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Malignant ascites (MA) is a distressing problem usually managed by repeated paracenteses. Paracentesis represents a meaningful time point in identifying patients with a specific presentation. OBJECTIVE:The objective of this study is to examine symptom clustering in MA patients at paracentesis. METHODS:Pre-...

journal_title：Annals of surgical oncology

authors： Husain A,Bezjak A,Easson A

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Mammary ductoscopy allows direct visualization of the ductal system and a method for directed excision and pathologic diagnosis. We reviewed our experience with mammary ductoscopy in the evaluation of pathologic nipple discharge. METHODS:We reviewed all patients who underwent ductoscopy for pathologic nipple...

journal_title：Annals of surgical oncology

authors： Fisher CS,Margenthaler JA

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:0.6-12.7% of patients with primary cutaneous melanoma will develop additional melanomas. Pathologic features of tumors in patients with multiple primary cutaneous melanomas have not been well described. In this large, international, multicenter, case-control study, we compared the clinicopathologic features ...

journal_title：Annals of surgical oncology

authors： Murali R,Goumas C,Kricker A,From L,Busam KJ,Begg CB,Dwyer T,Gruber SB,Kanetsky PA,Orlow I,Rosso S,Thomas NE,Berwick M,Scolyer RA,Armstrong BK,GEM Study Group.

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To investigate the influence of the introduction of total mesorectal excision (TME) on local recurrence rate and survival in patients with rectal cancer. METHODS:A total of 171 consecutive patients underwent anterior or abdominoperineal resection for primary rectal cancer. When the TME technique was introduced...

journal_title：Annals of surgical oncology

authors： Maurer CA,Renzulli P,Kull C,Käser SA,Mazzucchelli L,Ulrich A,Büchler MW

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The treatment strategy and benefit of extended lymph node dissection among patients with preoperatively diagnosed paraaortic lymph node metastasis (PALNM) in colon cancer remains highly controversial. In the current study, we analyzed the oncologic outcomes of patients who underwent extraregional lymph node ...

journal_title：Annals of surgical oncology

authors： Bae SU,Han YD,Cho MS,Hur H,Min BS,Baik SH,Lee KY,Kim NK

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DC) are potent professional antigen-presenting cells that can activate naive T lymphocytes and initiate cellular immune responses. As adjuvants, DC may be useful for enhancing immunogenicity and mediating tumor regression. Endogenous expression of antigen by DC could offer the potential adva...

journal_title：Annals of surgical oncology

authors： Kim CJ,Cormier J,Roden M,Gritz L,Mazzara GP,Fetsch P,Hijazi Y,Lee KH,Rosenberg SA,Marincola FM

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:In cutaneous melanoma (CM), the present methods of lymph node (LN) staging have not sufficiently utilized the prognostic information of metastatic LNs. In this study, we aimed to construct prognostic nomograms based on the number of positive LNs (PLNs) and other clinicopathologic characteristics of CM patien...

journal_title：Annals of surgical oncology

authors： Li W,Xu X,Zhang Y

更新日期：2021-01-11 00:00:00

abstract：BACKGROUND:Recently, many studies have demonstrated the feasibility and accuracy of sentinel lymph node (SLN) biopsy for patients treated with neoadjuvant chemotherapy (NAC). However, no studies have been conducted to evaluate the accuracy of frozen section (FS) analysis of SLN in NAC-treated patients. The aim was to e...

journal_title：Annals of surgical oncology

authors： Shimazu K,Tamaki Y,Taguchi T,Tsukamoto F,Kasugai T,Noguchi S

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Some reports have stated that pancreatoduodenectomy for elderly patients have comparable morbidity and mortality to that of young patients. However, the long-term outcomes of these patients have not been fully evaluated, especially for pancreatic head cancer. METHODS:A total of 227 patients who underwent pa...

journal_title：Annals of surgical oncology

authors： Sugiura T,Okamura Y,Ito T,Yamamoto Y,Ashida R,Uesaka K

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:The traditional Billroth II and Roux-en-Y anastomosis after laparoscopic distal gastrectomy for gastric cancer are associated with bile reflux gastritis and roux stasis syndrome, respectively. The uncut Roux-en-Y gastrojejunostomy can decrease the incidence of these complications by blocking the entry of bil...

journal_title：Annals of surgical oncology

authors： Wang J,Wang Q,Dong J,Yang K,Ji S,Fan Y,Wang C,Ma Q,Wei Q,Ji G

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:With cholangiocarcinoma, the only hope of a cure is resection. This study was undertaken to determine the impact of margin status, stage, tumor location, and adjuvant therapy on survival after resection of extrahepatic cholangiocarcinoma. METHODS:From 1985-2006, 91 patients underwent resections of cholangio...

journal_title：Annals of surgical oncology

authors： Hernandez J,Cowgill SM,Al-Saadi S,Villadolid D,Ross S,Kraemer E,Shapiro M,Mullinax J,Cooper J,Goldin S,Zervos E,Rosemurgy A

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:In patients with colorectal hepatic metastases, response rates with hepatic arterial infusion (HAI) FUdR (5-Fluoro-2-deoxyuridine) are significantly higher than with systemic fluoropyrimidines. We report a novel animal model of intrahepatic therapy for hepatic metastasis for the study of methods to increase ...

journal_title：Annals of surgical oncology

authors： Sutanto-Ward E,Arisawa Y,Tremiterra S,Sigurdson ER

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Trastuzumab in association with systemic cytotoxic chemotherapy is the standard of care for patients with advanced HER2-positive gastric carcinoma (GC). However, HER2 as a prognostic factor in GC remains controversial. METHODS:HER2 overexpression and amplification was evaluated by immunohistochemistry (IHC)...

journal_title：Annals of surgical oncology

authors： Cho J,Jeong J,Sung J,Sung CO,Kim KM,Park CK,Choi MG,Sohn TS,Bae JM,Kim S

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:The peritoneal cancer index (PCI) is used to refer gastrointestinal malignancy patients to either palliative or curative management of their peritoneal carcinomatosis. The aim of this retrospective study was to evaluate the prognostic value of the PCI in patients with primary advanced epithelial ovarian cancer ...

journal_title：Annals of surgical oncology

authors： Gasimli K,Braicu EI,Richter R,Chekerov R,Sehouli J

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Excess visceral adipose tissue may promote cancer development and progression via an obesity-related metabolic derangements, including adipocytokine-related inflammation, insulin resistance, and hypoxia. The relationship between visceral fat content and patient prognosis has been reported in some types of ca...

journal_title：Annals of surgical oncology

authors： Harada K,Baba Y,Ishimoto T,Kosumi K,Tokunaga R,Izumi D,Ida S,Imamura Y,Iwagami S,Miyamoto Y,Sakamoto Y,Yoshida N,Watanabe M,Baba H

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:We conducted a phase I clinical trial to evaluate the sensitivity, specificity, and safety of cytoreductive surgery (CRS) under aminolevulinic acid-mediated photodynamic diagnosis (ALA-PDD) plus hyperthermic intraperitoneal chemotherapy (HIPEC) on 20 patients with peritoneal carcinomatosis (PC) from ovarian ...

journal_title：Annals of surgical oncology

authors： Liu Y,Endo Y,Fujita T,Ishibashi H,Nishioka T,Canbay E,Li Y,Ogura S,Yonemura Y

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The benefit of adjuvant treatment in gastric adenocarcinoma was demonstrated by randomized, controlled trials of patients with locally advanced tumors. Thus, its role for stage IIB-IIIC disease is widely accepted. We aimed to identify patients with stage IA-IIA gastric adenocarcinoma who have a poor prognosi...

journal_title：Annals of surgical oncology

authors： Gold JS,Al Natour RH,Saund MS,Yoon C,Sharma AM,Huang Q,Boosalis VA,Whang EE

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:Basal subtype, as approximated by the triple-negative phenotype (ER-PR-Her2-), has correlated with higher LRR in recent studies. Indications for postmastectomy RT (PMRT) in women with 0-3 positive lymph nodes remain unclear. We evaluated the importance of biologic subtype in a cohort of women with LRR after mas...

journal_title：Annals of surgical oncology

authors： Khan AJ,Milgrom SA,Barnard N,Higgins SA,Moran M,Shahzad H,Kim S,Goyal S,Al-Faraj F,Kirstein L,Kearney T,Haffty BG

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Intraoperative ultrasound (IOUS)-guided lumpectomy in early breast cancer has shown advantages over other techniques. However, the use of IOUS has been less explored after neoadjuvant treatment (NAT). This study aimed to compare IOUS- and wire localization (WL)-guided surgery in breast cancer patients after ...

journal_title：Annals of surgical oncology

authors： Rubio IT,Esgueva-Colmenarejo A,Espinosa-Bravo M,Salazar JP,Miranda I,Peg V

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:This study aims to elucidate whether increasing the number of examined lymph nodes (NELN) is mandatory for the accurate prognosis of node-negative gastric cancer (GC) patients after curative gastrectomy in Eastern countries (China and Japan). METHODS:The clinicopathological data of 2455 GC patients (includi...

journal_title：Annals of surgical oncology

authors： Deng J,Yamashita H,Seto Y,Liang H

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Breast-conserving surgery (BCS) requires clear surgical margins to minimize local recurrence. We sought to identify groups of patients at higher risk of involved margins who might benefit from preoperative counselling and/or more generous excision at the first operation. METHODS:We reviewed demographic, cli...

journal_title：Annals of surgical oncology

authors： Kurniawan ED,Wong MH,Windle I,Rose A,Mou A,Buchanan M,Collins JP,Miller JA,Gruen RL,Mann GB

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Few studies have been undertaken to evaluate the prognostic value of age at diagnosis for determining breast cancer survival in a large population. METHODS:Using the U.S. National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database consisting of 18 population-based cancer registri...

journal_title：Annals of surgical oncology

authors： Liu YR,Jiang YZ,Yu KD,Shao ZM

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The 5th edition of Breast Imaging Reporting and Data System subdivides suspicious calcifications into two categories: 4B-amorphous, coarse heterogeneous, and fine pleomorphic calcifications; 4C-fine linear or fine linear branching calcifications. We investigated whether these revised categories are appropria...

journal_title：Annals of surgical oncology

authors： Kim SY,Kim HY,Kim EK,Kim MJ,Moon HJ,Yoon JH

更新日期：2015-09-01 00:00:00