Feasibility of breast preserving therapy with single fraction in situ radiotherapy delivered intraoperatively.

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNAB) of the thyroid categorized as atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) is a newly defined category according to the recent Bethesda guidelines. We sought to assess the characteristics and treatment of patients with an A...

journal_title：Annals of surgical oncology

authors： Nagarkatti SS,Faquin WC,Lubitz CC,Garcia DM,Barbesino G,Ross DS,Hodin RA,Daniels GH,Parangi S

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In several neoplastic diseases, including breast cancer, immunosuppression correlates with disease stage, progression, and outcome. Thus, thorough analysis of immune parameters in breast cancer patients may be beneficial in designing effective anticancer immune-based therapies. METHODS:We investigated dendr...

journal_title：Annals of surgical oncology

authors： Pockaj BA,Basu GD,Pathangey LB,Gray RJ,Hernandez JL,Gendler SJ,Mukherjee P

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Although advocated by some, minimally invasive adrenalectomy (MIA) for adrenocortical carcinoma (ACC) is controversial. Moreover, the oncologic implications for patients requiring conversion to an open procedure during attempted MIA for ACC are not extensively reported. PATIENTS AND METHODS:The National Can...

journal_title：Annals of surgical oncology

authors： Delozier OM,Stiles ZE,Deschner BW,Drake JA,Deneve JL,Glazer ES,Tsao MW,Yakoub D,Dickson PV

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:We sought to determine the competence of medical students and surgery residents in evaluating clinical problems (using both real and simulated patients) in surgical oncology. METHODS:Forty-five third-year medical students, 23 first postgraduate year (PGY-1) residents, and seven second postgraduate year (PGY...

journal_title：Annals of surgical oncology

authors： Sloan DA,Donnelly MB,Schwartz RW,Munch LC,Wells MD,Johnson SB,Strodel WE

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Lateral lymph node dissection (LND) in the absence of macroscopic nodal metastasis remains controversial in sporadic medullary thyroid carcinoma (MTC). OBJECTIVES:The aims of our study were to determine the risk of lateral lymph node (LN) metastases with a focus on lateral contralateral N1, and to define a ...

journal_title：Annals of surgical oncology

authors： Chandeze MM,Noullet S,Faron M,Trésallet C,Godiris-Petit G,Tissier F,Buffet C,Leenhardt L,Chereau N,Menegaux F

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node mapping (SLNM) and neoadjuvant chemotherapy are becoming established components of therapy for selected patients with breast carcinoma. However, neoadjuvant therapy has been considered a relative contraindication to SLNM. In an effort to learn whether patients who have received preoperati...

journal_title：Annals of surgical oncology

authors： Miller AR,Thomason VE,Yeh IT,Alrahwan A,Sharkey FE,Stauffer J,Otto PM,McKay C,Kahlenberg MS,Phillips WT,Cruz AB Jr

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Hyperthermic intraperitoneal chemotherapy (HIPEC) and complete surgical removal of the tumor, in relapsing patients may provide a clinical benefit. There is no consensus considering the place of HIPEC for patients who had first ovarian cancer relapse. To assess for possible efficacy of HIPEC on overall survi...

journal_title：Annals of surgical oncology

authors： Le Brun JF,Campion L,Berton-Rigaud D,Lorimier G,Marchal F,Ferron G,Oger AS,Dravet F,Jaffre I,Classe JM

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Extracapsular invasion (ECI) of metastatic axillary lymph nodes has been associated with aggressive nodal disease but its prognostic role in breast cancer is unclear. The present study evaluated nodal ECI as a predictor of breast cancer recurrence. METHODS:We evaluated 154 women with histologically proven n...

journal_title：Annals of surgical oncology

authors： Yajima R,Fujii T,Yanagita Y,Fujisawa T,Miyamoto T,Hirakata T,Tsutsumi S,Iijima M,Kuwano H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Although the National Comprehensive Cancer Network (NCCN) guidelines recommend use of lymph node dissection (LND) in patients with pancreatic neuroendocrine tumors (pNETs) > 2 cm, there is limited evidence to support the association between use of LND and overall survival (OS). METHODS:Patients with resecte...

journal_title：Annals of surgical oncology

authors： Mao R,Zhao H,Li K,Luo S,Turner M,Cai JQ,Blazer D 3rd

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Talimogene laherparepvec (T-VEC) is the first injectable oncolytic viral therapy approved for in-transit melanoma metastasis, with a reported overall response rate (ORR) of 25% and complete response rate (CRR) of 10%. To ascertain the role of patient selection on outcomes in routine practice, we evaluated th...

journal_title：Annals of surgical oncology

authors： Masoud SJ,Hu JB,Beasley GM,Stewart JH 4th,Mosca PJ

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Tumor growth and metastases require the development of new vessels (angiogenesis). Angiogenesis, assessed by microvessel count using immunocytochemical stain of endothelial cells, has been shown to predict metastases and correlate with early death. Recently developed color Doppler mapping can detect the "tum...

journal_title：Annals of surgical oncology

authors： Lee WJ,Chu JS,Houng SJ,Chung MF,Wang SM,Chen KM

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The aim of this clinical study was to evaluate quality of life (QoL) in early-stage breast cancer patients and to investigate the effects of a comprehensive rehabilitation program comparing women undergoing sentinel node biopsy (SNB) versus complete axillary lymph node dissection (ALND). QoL was assessed wit...

journal_title：Annals of surgical oncology

authors： Pinto e Silva MP,Sarian LO,Morais SS,Pace do Amaral MT,Freire de Oliveira MM,Derchain S

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Breast surgeons have a wide variety of intraoperative techniques available to help achieve low rates for positive margins of excision, with variable levels of evidence. METHODS:A systematic review of the medical literature from 1995 to July 2016 was conducted, with 434 abstracts identified and evaluated. Th...

journal_title：Annals of surgical oncology

authors： Gray RJ,Pockaj BA,Garvey E,Blair S

更新日期：2018-01-01 00:00:00

abstract：AIMS:To determine the incidence of lymph node (LN) metastasis in patients with apparently early carcinosarcoma of the uterus, to analyze the clinicopathologic factors associated with LN metastasis, and to evaluate the role of pelvic and/or para-aortic lymphadenectomy in treatment of such conditions. METHODS:We retrosp...

journal_title：Annals of surgical oncology

authors： Park JY,Kim DY,Kim JH,Kim YM,Kim YT,Nam JH

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Findings show that 5-10 % of women with a diagnosis of breast cancer (BCa) have actionable genetic mutations. The National Comprehensive Cancer Network guidelines for testing to detect BRCA1/2 mutations include personal history (PH) variables such as age of 45 years or younger and a family history (FH) varia...

journal_title：Annals of surgical oncology

authors： Kishan AU,Gomez CL,Dawson NA,Dvorak R,Foster NM,Hoyt A,Hurvitz SA,Kusske A,Silver EL,Tseng C,McCloskey SA

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Inguinal lymph node metastases (ILNM) from rectal adenocarcinoma are rare and staged as systemic disease. This study aimed to provide insight into the treatment and prognosis of ILNM from rectal adenocarcinoma. METHODS:All patients with a diagnosis of synchronous or metachronous ILNM from rectal adenocarcin...

journal_title：Annals of surgical oncology

authors： Hagemans JAW,Rothbarth J,van Bogerijen GHW,van Meerten E,Nuyttens JJME,Verhoef C,Burger JWA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:This prospective multicenter sentinel lymph node (SLN) trial investigated whether molecular analysis would improve the detection of SLN metastases and their prognostic value. We report mammaglobin quantitative real-time polymerase chain reaction (qRT-PCR) results and clinical outcome for 547 patients (mean f...

journal_title：Annals of surgical oncology

authors： Verbanac KM,Min CJ,Mannie AE,Lu J,O'Brien KF,Rosman M,Tafra L,ECU\/AAMC Sentinel Node Study Group.

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel approach to delivering intraperitoneal chemotherapy (IPC) as a pressurized aerosol. One of the assumed advantages is the homogeneous drug distribution in the intraperitoneal cavity compared with conventional liquid in situ chemotherapy. Howe...

journal_title：Annals of surgical oncology

authors： Khosrawipour V,Khosrawipour T,Diaz-Carballo D,Förster E,Zieren J,Giger-Pabst U

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:This study was designed to investigate whether postoperative infectious complications (ICs) are a risk factor for the prognosis in esophageal cancer patients who receive neoadjuvant chemotherapy by stratifying the response to neoadjuvant chemotherapy. METHODS:The present study retrospectively examined patie...

journal_title：Annals of surgical oncology

authors： Kano K,Aoyama T,Yoshikawa T,Maezawa Y,Nakajima T,Hayashi T,Yamada T,Sato T,Oshima T,Rino Y,Masuda M,Cho H,Ogata T

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:The transcription factor NF-E2-related factor 2 (Nrf2) was originally identified to be a critical regulator of intracellular antioxidants and phase II detoxification enzymes. Recent studies have shown that high Nrf2 expression gives cancer cells an advantage for survival from anticancer chemotherapy and radi...

journal_title：Annals of surgical oncology

authors： Kawasaki Y,Okumura H,Uchikado Y,Kita Y,Sasaki K,Owaki T,Ishigami S,Natsugoe S

更新日期：2014-07-01 00:00:00

abstract：:Between 1980 and 2004, six randomized, controlled trials (RCTs) have been performed to evaluate the width of surgical margin excision for primary cutaneous melanoma and its influence on recurrence and survival. These trials have led to the current recommendation of not more than a 2-cm margin excision and have allowed...

journal_title：Annals of surgical oncology

authors： Angeles CV,Wong SL,Karakousis G

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Preoperative cutaneous lymphoscintigraphy (LS) to identify sentinel (first-tier) lymph nodes was performed in 250 consecutive melanoma patients before wide local excision only or wide local excision with sentinel node biopsy. METHODS:The location of the sentinel nodes was marked on the overlying skin in all...

journal_title：Annals of surgical oncology

authors： Uren RF,Howman-Giles RB,Thompson JF

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:The status of the sentinel lymph node is an important predictor for survival in melanoma patients, but it is still unclear if early removal of micrometastases by sentinel lymph node dissection (SLND) alters survival. A large series of melanoma patients from a single center with long-term follow-up was analyz...

journal_title：Annals of surgical oncology

authors： Satzger I,Meier A,Hoy L,Völker B,Kapp A,Hauschild A,Gutzmer R

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Using 4-year nationwide population-based data for Taiwan, this study compared in-hospital surgical mortality rates with hospital volume for five cancer-related gastrointestinal resections. METHODS:The study sample was drawn from the Taiwan National Health Insurance Research Database. A total of 34,715 patie...

journal_title：Annals of surgical oncology

authors： Lin HC,Xirasagar S,Lee HC,Chai CY

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:The impact of postoperative complications on the administration of adjuvant therapy following pancreaticoduodenectomy (PD) for adenocarcinoma is still unclear. METHODS:A retrospective review of all patients undergoing PD at our institution between 1995 and 2011 was performed. Clinicopathological data, inclu...

journal_title：Annals of surgical oncology

authors： Wu W,He J,Cameron JL,Makary M,Soares K,Ahuja N,Rezaee N,Herman J,Zheng L,Laheru D,Choti MA,Hruban RH,Pawlik TM,Wolfgang CL,Weiss MJ

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Here, we explored the genetic interactions between diabetes and oncogenic single-nucleotide polymorphisms (SNPs) that determine colorectal cancer (CRC) morbidity. METHODS:8q24 rs6983267 polymorphism analysis and cDNA microarray were performed in 107 CRCs to identify the genes associated with diabetes and th...

journal_title：Annals of surgical oncology

authors： Sugimachi K,Yamaguchi R,Eguchi H,Ueda M,Niida A,Sakimura S,Hirata H,Uchi R,Shinden Y,Iguchi T,Morita K,Yamamoto K,Miyano S,Mori M,Maehara Y,Mimori K

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Visceral fat accumulation and muscle depletion have been identified as poor prognostic factors for various cancers. However, the significance of visceral adiposity and sarcopenic visceral obesity on outcomes after resection of pancreatic cancer remains unclear. METHODS:A retrospective analysis of 301 patien...

journal_title：Annals of surgical oncology

authors： Okumura S,Kaido T,Hamaguchi Y,Kobayashi A,Shirai H,Yao S,Yagi S,Kamo N,Hatano E,Okajima H,Takaori K,Uemoto S

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The sentinel lymph node (SLN) concept has been gaining attention for gastrointestinal neoplasms but remains controversial for esophageal cancer. This study evaluated the feasibility of SLN identification using intraoperative indocyanine green (ICG) fluorescence imaging (IGFI) navigated by preoperative comput...

journal_title：Annals of surgical oncology

authors： Yuasa Y,Seike J,Yoshida T,Takechi H,Yamai H,Yamamoto Y,Furukita Y,Goto M,Minato T,Nishino T,Inoue S,Fujiwara S,Tangoku A

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the correlation between clinical complete response (cCR) and pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (CRT) for esophageal squamous cell cancer (ESCC). METHODS:Between May 2001 and April 2013, a total of 158 patients with thoracic ESCC tr...

journal_title：Annals of surgical oncology

authors： Liu SL,Xi M,Yang H,Yang YD,Wu YJ,Zhao L,Zhang P,Luo LL,Liu MZ

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Regional nodal status is the most powerful predictor of recurrence and survival in women with breast cancer. Lymphatic mapping and sentinel lymph node (SLN) biopsy have been found to accurately predict the regional nodal status. Preoperative lymphoscintigraphy has been used in melanoma patients to identify...

journal_title：Annals of surgical oncology

authors： Dupont EL,Kamath VJ,Ramnath EM,Shivers SC,Cox C,Berman C,Leight GS Jr,Ross MI,Blumencranz P,Reintgen DS,DOD Breast Lymphatic Mapping Trial Investigators.

更新日期：2001-05-01 00:00:00