Anti-tumor effects and tumor immunogenicity following IL2 or IL4 cytokine gene transfection of three mouse mammary tumors.

abstract：BACKGROUND:The use of routine CT imaging for surveillance in asymptomatic patients with cutaneous melanoma is controversial. We report our experience using a surveillance strategy that included CT imaging for a cohort of patients with high-risk melanoma. METHODS:A total of 466 patients with high-risk cutaneous melanom...

journal_title：Annals of surgical oncology

authors： Park TS,Phan GQ,Yang JC,Kammula U,Hughes MS,Trebska-McGowan K,Morton KE,White DE,Rosenberg SA,Sherry RM

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Postmastectomy radiation (PMRT) and regional nodal irradiation (RNI) improve outcomes for patients at high risk of locoregional recurrence (LRR). Node-negative patients with the triple-negative (TN) subtype and those who do not have a pCR with neoadjuvant chemotherapy (NAC) are at increased risk for LRR, but...

journal_title：Annals of surgical oncology

authors： Crown A,Gonen M,Le T,Morrow M

更新日期：2020-09-21 00:00:00

abstract：BACKGROUND:Clinical trials report improved overall survival following neoadjuvant chemoradiotherapy in patients undergoing surgery for esophageal adenocarcinoma, with a 10-15% survival improvement. MicroRNAs (miRNAs) are small noncoding RNAs that are known to direct the behavior of cancers, including response to treatm...

journal_title：Annals of surgical oncology

authors： Chiam K,Mayne GC,Watson DI,Woodman RJ,Bright TF,Michael MZ,Karapetis CS,Irvine T,Phillips WA,Hummel R,Wang T,Pimlott LK,Marri S,Astill DS,Ruszkiewicz AR,Thompson SK,Hussey DJ

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Achieving an undetectable serum thyroglobulin (Tg) level (<1.0 ng/mL) after surgical and radioiodine treatment for papillary thyroid cancer (PTC) is associated with low recurrence rates and has been termed biochemical remission. This study aimed to determine the effectiveness of total thyroidectomy with ther...

journal_title：Annals of surgical oncology

authors： Hughes DT,Miller BS,Cohen MS,Doherty GM,Gauger PG

更新日期：2014-05-01 00:00:00

abstract：:In 2009, 2 single-institution studies from the United States reported increasing mastectomy rates during the last decade. We have recently reported unilateral mastectomy trends from a European database and demonstrated a significant trend of decreasing mastectomy rates from 38.1 % in 2005 to 13.1 % in 2010. A recent s...

journal_title：Annals of surgical oncology

authors： Garcia-Etienne CA,Tomatis M,Heil J,Danaei M,Rageth CJ,Marotti L,Rosselli Del Turco M,Ponti A

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Circulating ('blood-borne') tissue factor (TF) is implicated in the pathogenesis of several chronic conditions, most notably cardiovascular disease, diabetes, and cancer. Full-length TF is an integral membrane protein, while alternatively spliced TF (asTF) can be secreted and, owing to its unique C-terminus,...

journal_title：Annals of surgical oncology

authors： Unruh D,Sagin F,Adam M,Van Dreden P,Woodhams BJ,Hart K,Lindsell CJ,Ahmad SA,Bogdanov VY

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Identification of novel molecules implicated in the malignancy of gastric cancer (GC) is key to the development of personalized treatments and the improvement of patient outcome. Neurotrophin receptor-interacting melanoma antigen-encoding protein (NRAGE) regulates apoptosis and metastasis via interactions wi...

journal_title：Annals of surgical oncology

authors： Kanda M,Shimizu D,Fujii T,Tanaka H,Tanaka Y,Ezaka K,Shibata M,Takami H,Hashimoto R,Sueoka S,Iwata N,Kobayashi D,Tanaka C,Yamada S,Nakayama G,Sugimoto H,Koike M,Fujiwara M,Kodera Y

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Granulomatous mastitis is an uncommon chronic inflammatory breast condition that is characterized by granulomatous inflammation. Granulomatous mastitis presents a challenging clinical scenario, because it can mimic carcinoma. The etiology and optimal treatment remain unclear. We report our experience with gr...

journal_title：Annals of surgical oncology

authors： Joseph KA,Luu X,Mor A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The term pseudomyxoma peritonei has been used in reference to any condition, benign or malignant, in which the peritoneal cavity becomes filled with a gelatinous substance. The term is nonspecific and does not denote therapeutic or prognostic significance. Controversy centers around which patients benefit fr...

journal_title：Annals of surgical oncology

authors： Wirtzfeld DA,Rodriguez-Bigas M,Weber T,Petrelli NJ

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Osteopontin (OPN) is a secreted, integrin-binding glycophosphoprotein that has been implicated in the progression of various solid tumors. To evaluate the clinical significance of OPN in gastric carcinoma, we investigated OPN expression in resected tumors. METHODS:Expression of OPN protein by gastric cancer...

journal_title：Annals of surgical oncology

authors： Higashiyama M,Ito T,Tanaka E,Shimada Y

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Adaptor proteins, with multimodular structures, can participate in the regulation of various cellular functions. A novel adaptor protein XB130 has been implicated as a substrate and regulator of tyrosine kinase-mediated signaling and in controlling cell proliferation and apoptosis in thyroid and lung cancer ...

journal_title：Annals of surgical oncology

authors： Shiozaki A,Kosuga T,Ichikawa D,Komatsu S,Fujiwara H,Okamoto K,Iitaka D,Nakashima S,Shimizu H,Ishimoto T,Kitagawa M,Nakou Y,Kishimoto M,Liu M,Otsuji E

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Axillary nodal status is the most important prognostic factor for patients with breast cancer. Clinical assessment and imaging modalities are not always reliable. Surgical removal and histopathological examination of axillary lymph nodes remain essential methods of staging the axilla. However, the optimal ma...

journal_title：Annals of surgical oncology

authors： Samphao S,Eremin JM,El-Sheemy M,Eremin O

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Esophageal cancer is an aggressive cancer with poor prognosis. However, little is known about the immune response in the tumor microenvironment after neoadjuvant chemotherapy. PURPOSE:To investigate the immunological impact of neoadjuvant chemotherapy in the tumor microenvironment of esophageal squamous cel...

journal_title：Annals of surgical oncology

authors： Tsuchikawa T,Miyamoto M,Yamamura Y,Shichinohe T,Hirano S,Kondo S

更新日期：2012-05-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Park YM,Kim SH

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Cancer patients have often been reported to have impaired immune function, and the effect of treatment modalities, such as surgery, irradiation, and chemotherapy, in depressing patients' immunity has also been reported. In this investigation, the effect of treatment on the cellular immunity of esophageal can...

journal_title：Annals of surgical oncology

authors： Mafune K,Tanaka Y

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is standard treatment for peritoneal dissemination from appendiceal cancer (AC); however, its role in high-grade histopathologic subtypes (high-grade mucinous carcinoma peritonei [HGMCP] and HGMCP with signet ring cells [HGMCP-S]...

journal_title：Annals of surgical oncology

authors： Munoz-Zuluaga C,Sardi A,King MC,Nieroda C,Sittig M,MacDonald R,Gushchin V

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Cryotherapy is a method of in situ destruction of tumors by freeze/thaw mechanisms. Cancer cells located in the peripheral zone of the tumor undergoing cryotherapy can die by apoptosis. We hypothesized that p21WAF1 is involved in the mediation of cryotherapy-induced apoptosis. METHODS:HT29 cells grown on a ...

journal_title：Annals of surgical oncology

authors： Sharma RR,Ravikumar TS,Raimo D,Yang WL

更新日期：2005-09-01 00:00:00

abstract：:Parietal peritonectomy is an initial part of cytoreductive surgery in patients with peritoneal surface malignancy. After this dissection, the necessary visceral resections, other peritonectomy procedures, and perioperative hyperthermic chemotherapy are administered. The parietal peritoneum is an immobile portion of th...

journal_title：Annals of surgical oncology

authors： Sugarbaker PH

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The role neoadjuvant chemoradiotherapy (nCRT) plays in oncological outcomes in early T-stage rectal cancer is uncertain. The present work aims to clarify prognostic outcomes by estimating the effect of nCRT on tumor recurrence prior to major surgery compared with major surgery alone. PATIENTS AND METHODS:Pr...

journal_title：Annals of surgical oncology

authors： Hayes IP,Milanzi E,Gibbs P,Reece JC

更新日期：2020-05-01 00:00:00

abstract：:The surveillance of breast cancer patients after potentially curative treatment may result in the identification of locoregional or distant recurrence. While many patients expect frequent imaging studies to monitor for recurrence, there are no data supporting aggressive imaging surveillance beyond mammography. However...

journal_title：Annals of surgical oncology

authors： Leitch AM

更新日期：2013-10-01 00:00:00

abstract：:Multiple randomized trials, as well as a meta-analysis of these studies, have confirmed the equivalence of breast-conservation and mastectomy. In addition, in unselected populations, adjuvant radiation therapy following lumpectomy has been shown to decrease in-breast recurrence and improve overall survival. However, r...

journal_title：Annals of surgical oncology

authors： Bellon JR,Golshan M,Solin LJ

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:The aim of this study is to evaluate the safety and efficacy of induction modified 5-fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) plus bevacizumab followed by S- 1-based chemoradiotherapy in magnetic resonance imaging (MRI)-defined poor-risk locally advanced low rectal cancer. PATIENTS AND METHODS:This...

journal_title：Annals of surgical oncology

authors： Konishi T,Shinozaki E,Murofushi K,Taguchi S,Fukunaga Y,Nagayama S,Fujimoto Y,Akiyoshi T,Nagasaki T,Suenaga M,Chino A,Kawachi H,Yamamoto N,Ishikawa Y,Oguchi M,Ishizuka N,Ueno M,Yamaguchi K

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:For some types of cancer, postoperative complications can negatively influence survival, but the association between these complications and oncological outcomes is unclear for patients with esophageal cancer who receive preoperative treatments. METHODS:Data were retrospectively analyzed for patients who un...

journal_title：Annals of surgical oncology

authors： Yamashita K,Makino T,Miyata H,Miyazaki Y,Takahashi T,Kurokawa Y,Yamasaki M,Nakajima K,Takiguchi S,Mori M,Doki Y

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Oral health is associated with various diseases, including cancer. Tooth loss is a simple and objective index of oral health. OBJECTIVE:The purpose of this study was to investigate the association between preoperative tooth loss and esophageal cancer prognosis after esophagectomy. METHODS:This study includ...

journal_title：Annals of surgical oncology

authors： Miura S,Nakamura T,Hasegawa T,Miura Y,Takiguchi G,Urakawa N,Hasegawa H,Yamamoto M,Kanaji S,Matsuda Y,Yamashita K,Matsuda T,Oshikiri T,Suzuki S,Akashi M,Kakeji Y

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:Controversy over the need for sentinel node biopsy (SNB) continues to exist for the optimal treatment of breast cancer in patients ≥ 70 years of age, especially in those with lower-risk disease. Clinicians must balance competing risks to give the best individualized care. METHODS:The American Society of B...

journal_title：Annals of surgical oncology

authors： Blair SL,Tsai C,Tafra L

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:Retroperitoneal sarcomas (RPS) are rare malignancies, comprising just 10-15 % of all soft-tissue sarcomas. These are challenging tumors to treat, with surgical resection being the only modality capable of providing a cure. This study analyzed the management and survival of patients resected at a large academic ...

journal_title：Annals of surgical oncology

authors： Bremjit PJ,Jones RL,Chai X,Kane G,Rodler ET,Loggers ET,Pollack SM,Pillarisetty VG,Mann GN

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:We previously reported that the one-step nucleic acid amplification (OSNA) assay provided a judgment performance for colorectal cancer equivalent to a 2-mm-interval histopathological examination of lymph nodes (concordance 97.1 %, n = 385 lymph nodes). In this prospective multicenter study, we uncovered an O...

journal_title：Annals of surgical oncology

authors： Yamamoto H,Tomita N,Inomata M,Furuhata T,Miyake Y,Noura S,Kato T,Murata K,Hayashi S,Igarashi S,Itabashi M,Kameoka S,Matsuura N

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Inflammation has been demonstrated to promote cancer metastasis. Due to the well-known systemic inflammatory responses (SIR) after major surgery, it is critical to investigate and attenuate SIR-induced tumor metastasis of cancer patients suffering surgical procedures. METHODS:C57BL/6 mice were intravenously...

journal_title：Annals of surgical oncology

authors： Zhang X,Moriwaki T,Kawabata T,Goto S,Liu KX,Guo CY,Li TS

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Cancer treatment costs are not routinely addressed in shared decisions for breast cancer surgery. Thus, we sought to characterize cost awareness and communication among surgeons treating breast cancer. METHODS:We conducted a self-administered, confidential electronic survey among members of the American Soc...

journal_title：Annals of surgical oncology

authors： Greenup RA,Rushing CN,Fish LJ,Lane WO,Peppercorn JM,Bellavance E,Tolnitch L,Hyslop T,Myers ER,Zafar SY,Hwang ES

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Our objective was to correlate the extent of margin positivity and the findings on re-excision specimens of infiltrating mammary carcinoma. METHODS:We selected 50 consecutive cases of infiltrating mammary carcinoma, including both infiltrating ductal carcinoma and infiltrating lobular carcinoma, with positi...

journal_title：Annals of surgical oncology

authors： Darvishian F,Hajdu SI,DeRisi DC

更新日期：2003-01-01 00:00:00