Trends in the treatment and outcome of pancreatic cancer in the United States.

abstract：BACKGROUND:AT-rich interactive domain 3A (ARID3A) is a member of the ARID family of DNA-binding proteins. Previous reports have shown that ARID3A controls cell growth in a p53-dependent manner. Recently, it has been reported that expression of the ARID3A protein was markedly increased in colon cancer tissue compared wi...

journal_title：Annals of surgical oncology

authors： Song M,Kim H,Kim WK,Hong SP,Lee C,Kim H

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Tumor thickness and nodal status are important predictors of survival following curative resection for gastric cancer. Lymphovascular invasion (LVI) is a potential predictor of biological behavior. The relationship between LVI and tumor thickness (T status) has not been established in population-based studie...

journal_title：Annals of surgical oncology

authors： Dicken BJ,Saunders LD,Jhangri GS,de Gara C,Cass C,Andrews S,Hamilton SM

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Isolated hepatic perfusion has been used in patients with colorectal cancer (CRC) metastatic to the liver. We sought to determine whether perfusion with antisense oligodeoxynucleotides results in the downregulation of beta-catenin and whether this improves tumor response to isolated limb perfusion (ILP) in a...

journal_title：Annals of surgical oncology

authors： Canter RJ,Kesmodel SB,Heitjan DF,Veeramachaneni NK,Mokadam NA,Drebin JA,Fraker DL

更新日期：2005-09-01 00:00:00

abstract：:Multiple randomized trials, as well as a meta-analysis of these studies, have confirmed the equivalence of breast-conservation and mastectomy. In addition, in unselected populations, adjuvant radiation therapy following lumpectomy has been shown to decrease in-breast recurrence and improve overall survival. However, r...

journal_title：Annals of surgical oncology

authors： Bellon JR,Golshan M,Solin LJ

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Currently, cytoreductive surgery and hyperthermic intraperitoneal chemotherapy are accepted treatments for surgically resectable appendiceal epithelial neoplasms. However, for nonsurgical candidates, systemic treatment may be considered. The purpose of this analysis was to determine the benefit of biologic t...

journal_title：Annals of surgical oncology

authors： Choe JH,Overman MJ,Fournier KF,Royal RE,Ohinata A,Rafeeq S,Beaty K,Phillips JK,Wolff RA,Mansfield PF,Eng C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Male breast cancer accounts for less than 1% of all breast cancers, yet males have a worse prognosis than females with breast cancer. METHODS:Using the 1988-2003 Surveillance, Epidemiology, and End Results Program data, we conducted a retrospective, population-based cohort study to investigate stage-specifi...

journal_title：Annals of surgical oncology

authors： Gnerlich JL,Deshpande AD,Jeffe DB,Seelam S,Kimbuende E,Margenthaler JA

更新日期：2011-07-01 00:00:00

abstract：INTRODUCTION:The National Comprehensive Cancer Network (NCCN) developed clinical practice guidelines for germline pathogenic variants in highly penetrant genes, such as TP53 and PTEN, and in moderately penetrant genes, such as CHEK2, ATM and PALB2. Whether the practice of radiographic surveillance of patients with path...

journal_title：Annals of surgical oncology

authors： Hudson L,Gower N,Lenarcic S,Trufan SJ,White RL Jr

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:To determine the risk factors related to adnexal involvement in endometrial cancer (EC) and its implications for ovarian preservation in young women. METHODS:We analyzed a series of 802 patients who were treated at AC Camargo Cancer Center from July 1991 to July 2017. Patients who had peritoneal or systemic di...

journal_title：Annals of surgical oncology

authors： Baiocchi G,Clemente AG,Mantoan H,da Costa WL Jr,Bovolim G,Guimaraes APG,da Costa AABA,De Brot L,Faloppa CC

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:This study was designed to describe patient, disease, and treatment characteristics of women diagnosed with breast cancer at the Breast Examination Center of Harlem (BECH) and to determine whether these characteristics have changed over time. METHODS:Retrospective chart review of women diagnosed with breast...

journal_title：Annals of surgical oncology

authors： Manning AT,Eaton A,Azu M,Sampson M,Patil S,Godfrey D,Beesen AA,Liberman L,Gemignani ML

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The clinical impact of sentinel lymph node biopsy (SLNB) in gastric cancer is controversial. We performed a prospective trial to compare different methods: radiocolloid method (RM), dye method (DM), and both methods simultaneously (dual method, or DUM) for reliability and therapeutic consequences. METHODS:R...

journal_title：Annals of surgical oncology

authors： Gretschel S,Bembenek A,Hünerbein M,Dresel S,Schneider W,Schlag PM

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:The sentinel lymph node (SLN) concept has been gaining attention for gastrointestinal neoplasms but remains controversial for esophageal cancer. This study evaluated the feasibility of SLN identification using intraoperative indocyanine green (ICG) fluorescence imaging (IGFI) navigated by preoperative comput...

journal_title：Annals of surgical oncology

authors： Yuasa Y,Seike J,Yoshida T,Takechi H,Yamai H,Yamamoto Y,Furukita Y,Goto M,Minato T,Nishino T,Inoue S,Fujiwara S,Tangoku A

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node biopsy (SLNB) has become a standard for axillary staging for early breast cancer patients. Prior studies suggest that SLNB may be more sensitive for the identification of lymph node disease than axillary lymph node dissection (ALND). We hypothesized that SLNB use increases the incidence o...

journal_title：Annals of surgical oncology

authors： Vanderveen KA,Schneider PD,Khatri VP,Goodnight JE,Bold RJ

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Patients want information to search for destination of care for breast-conserving surgery (BCS). To inform patients wanting a lumpectomy, we aimed to develop a pilot project that communicated composite quality measure (QM) results using a '4-star' rating system. Two patient-centered QMs were included in the ...

journal_title：Annals of surgical oncology

authors： Dunham AL,Ramirez LD,Vang CA,Linebarger JH,Landercasper J

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:We sought to examine how splenectomy as part of up-front cytoreductive surgery in ovarian cancer influences the postoperative course and affects survival. METHODS:We reviewed cases of ovarian cancer diagnosed at Massachusetts General Hospital from 1994 to 2008 and found 44 patients who had a splenectomy as par...

journal_title：Annals of surgical oncology

authors： McCann CK,Growdon WB,Munro EG,Del Carmen MG,Boruta DM,Schorge JO,Goodman A

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Reactive oxygen species (free radicals) play an important role in carcinogenesis. Extensive antioxidant defense mechanisms counteract free radicals in mammalian cells. Oxidative stress is a disturbance in the balance between the production of free radicals and antioxidant defenses. There is direct evidence t...

journal_title：Annals of surgical oncology

authors： Kilic N,Yavuz Taslipinar M,Guney Y,Tekin E,Onuk E

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Hepatitis B (HBV)-associated hepatocellular carcinoma (HCC) is often associated with alpha-fetoprotein (AFP) production. Although serum AFP has been demonstrated to be a prognostic factor for patient survival, optimal cutoff levels remain unclear. METHODS:Patients with HBV-associated HCC treated by primary ...

journal_title：Annals of surgical oncology

authors： Blank S,Wang Q,Fiel MI,Luan W,Kim KW,Kadri H,Mandeli J,Hiotis SP

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The utility of sentinel lymph node biopsy (SLNB) for desmoplastic melanoma (DM) is debated. We describe a large single-institution experience with SLNB for DM to determine clinicopathologic factors predictive of SLN metastasis. METHODS:Retrospective review identified 205 patients with DM who underwent SLNB ...

journal_title：Annals of surgical oncology

authors： Han D,Zager JS,Yu D,Zhao X,Walls B,Marzban SS,Rao NG,Sondak VK,Messina JL

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:There is substantial variation in the surgical complexity of hepatectomy. Currently, the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) risk adjusts for hospital quality comparisons using only the primary procedure code. Our objectives were to (1) assess the associatio...

journal_title：Annals of surgical oncology

authors： Paruch JL,Merkow RP,Bentrem DJ,Ko CY,Posner MC,Cohen ME,Bilimoria KY,Weber SM

更新日期：2014-06-01 00:00:00

abstract：:Adenocarcinoma of the pancreas continues to be a formidable disease. In the United States, patients who have had resected disease are generally offered adjuvant chemoradiation. The current National Comprehensive Cancer Network practice guidelines uniformly support this practice. We reviewed seven selected series to ev...

journal_title：Annals of surgical oncology

authors： Chu QD,Khushalani N,Javle MM,Douglass HO Jr,Gibbs JF

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Esophageal cancer frequently metastasizes to lymph nodes along the recurrent laryngeal nerve (RLN),1 therefore it is essential to dissect RLN nodes for curative esophagectomy.2 Right-sided aortic arch (RAA), a rare congenital anomaly, occurs in approximately 0.1% of adults.3 Because RAA forms a vascular ring...

journal_title：Annals of surgical oncology

authors： Okamura A,Watanabe M,Yuda M,Shoji Y,Yamashita K,Hayami M,Imamura Y,Mine S

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Although the National Comprehensive Cancer Network (NCCN) guidelines recommend use of lymph node dissection (LND) in patients with pancreatic neuroendocrine tumors (pNETs) > 2 cm, there is limited evidence to support the association between use of LND and overall survival (OS). METHODS:Patients with resecte...

journal_title：Annals of surgical oncology

authors： Mao R,Zhao H,Li K,Luo S,Turner M,Cai JQ,Blazer D 3rd

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Response to chemotherapy and anatomical spread are significant prognostic factors in patients with esophageal squamous cell carcinoma (ESCC) treated by chemotherapy then surgery. Predicting the response to chemotherapy would allow significant optimization of cancer treatment. METHODS:Genomic mutation and pr...

journal_title：Annals of surgical oncology

authors： Yamasaki M,Miyata H,Fujiwara Y,Takiguchi S,Nakajima K,Nishida T,Yasuda T,Matsuyama J,Mori M,Doki Y

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Inflammatory breast cancer (IBC) is an aggressive form of breast cancer characterized by rapid progression and early metastatic dissemination. The purpose of this study was to assess contemporary rates of local regional recurrence (LRR) in the era of trimodality therapy for nonmetastatic IBC and identify ris...

journal_title：Annals of surgical oncology

authors： Rosso KJ,Tadros AB,Weiss A,Warneke CL,DeSnyder S,Kuerer H,Ueno NT,Stecklein SR,Woodward WA,Lucci A

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Integration of palliative care services into the surgical treatment plan is important for holistic patient care. We sought to examine the association between patient race/ethnicity and county-level vulnerability relative to patterns of hospice utilization. PATIENTS AND METHODS:Medicare Standard Analytic Fil...

journal_title：Annals of surgical oncology

authors： Abbas A,Madison Hyer J,Pawlik TM

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Osteopontin (OPN) is a secreted, integrin-binding glycophosphoprotein that has been implicated in the progression of various solid tumors. To evaluate the clinical significance of OPN in gastric carcinoma, we investigated OPN expression in resected tumors. METHODS:Expression of OPN protein by gastric cancer...

journal_title：Annals of surgical oncology

authors： Higashiyama M,Ito T,Tanaka E,Shimada Y

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Arginine plays a pivotal role in regulating ureagenesis, polyamine biosynthesis, and nitric oxide production, metabolic pathways that may be stimulated in the liver of the tumor-bearing host. Normally, plasma arginine is excluded from the hepatocyte intracellular space by the low basal activity of its membra...

journal_title：Annals of surgical oncology

authors： Espat NJ,Copeland EM,Souba WW

更新日期：1994-03-01 00:00:00

abstract：:The purpose of this study was to clarify the outcome of the ratio between metastatic and examined lymph nodes (N ratio) in gastric cancer patients with < or =15 examined lymph nodes after D2 lymphadenectomy. A retrospective study was performed in 906 patients with gastric cancer who had undergone D2 resection. Patient...

journal_title：Annals of surgical oncology

authors： Xu DZ,Geng QR,Long ZJ,Zhan YQ,Li W,Zhou ZW,Chen YB,Sun XW,Chen G,Liu Q

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:In 2003, the American Joint Committee on Cancer (AJCC) initiated the 6th edition staging criteria, including pN0(i+) and pN1mi categories for breast cancer. However, the clinical significance of these categories is debated in the literature. METHODS:A prospective registry was used to identify patients stage...

journal_title：Annals of surgical oncology

authors： Pugliese MS,Beatty JD,Tickman RJ,Allison KH,Atwood MK,Szymonifka J,Arthurs ZM,Huynh PP,Dawson JH

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The aim of this retrospective analysis was to analyze the results of treatment of patients with cervical node metastases from carcinoma of occult primary with a policy including neck dissection and postoperative comprehensive radiotherapy. METHODS:Ninety patients were treated with curative intent from 1990 ...

journal_title：Annals of surgical oncology

authors： Boscolo-Rizzo P,Gava A,Da Mosto MC

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Various patient, treatment, and pathologic factors have been associated with an increased risk of local recurrence (LR) following breast-conserving therapy (BCT) for ductal carcinoma in situ (DCIS). However, the strength and importance of individual factors has varied; whether combining factors improves pred...

journal_title：Annals of surgical oncology

authors： Collins LC,Achacoso N,Haque R,Nekhlyudov L,Quesenberry CP Jr,Schnitt SJ,Habel LA,Fletcher SW

更新日期：2015-12-01 00:00:00