Gastric cancer: establishing predictors of biologic behavior with use of population-based data.

abstract：BACKGROUND:Findings show that 5-10 % of women with a diagnosis of breast cancer (BCa) have actionable genetic mutations. The National Comprehensive Cancer Network guidelines for testing to detect BRCA1/2 mutations include personal history (PH) variables such as age of 45 years or younger and a family history (FH) varia...

journal_title：Annals of surgical oncology

authors： Kishan AU,Gomez CL,Dawson NA,Dvorak R,Foster NM,Hoyt A,Hurvitz SA,Kusske A,Silver EL,Tseng C,McCloskey SA

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Surgery is the standard treatment for primary, gastrointestinal stromal tumor (GIST); however, surgical resection often is not curative, particularly in large GIST. Five years after complete removal of their tumor, approximately half of treated patients relapse. Imatinib, an oral tyrosine kinase inhibitor (T...

journal_title：Annals of surgical oncology

authors： Hohenberger P,Eisenberg B

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:There is conflicting evidence concerning platelet status and hepatocellular carcinoma (HCC) prognosis. We evaluated the prognostic value of platelet-based indices, including platelet count, platelet/lymphocyte ratio (PLR), and aspartate aminotransferase to platelet ratio index (APRI) in HCC after hepatic res...

journal_title：Annals of surgical oncology

authors： Shen SL,Fu SJ,Chen B,Kuang M,Li SQ,Hua YP,Liang LJ,Guo P,Hao Y,Peng BG

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Recent adjuvant chemotherapy trials after resection of stage II and III non-small cell lung cancer (NSCLC) have identified important survival differences among patients with immunohistochemical evidence suggesting platinum resistance. No clinical information exists regarding the impact upon survival of patie...

journal_title：Annals of surgical oncology

authors： d'Amato TA,Pettiford BL,Schuchert MJ,Parker R,Ricketts WA,Luketich JD,Landreneau RJ

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Integration of palliative care services into the surgical treatment plan is important for holistic patient care. We sought to examine the association between patient race/ethnicity and county-level vulnerability relative to patterns of hospice utilization. PATIENTS AND METHODS:Medicare Standard Analytic Fil...

journal_title：Annals of surgical oncology

authors： Abbas A,Madison Hyer J,Pawlik TM

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:CD44 isoforms serve as a marker for cancer stem cells. CD44 variant 9 (CD44v9) contributes to the defense against reactive oxygen species, resulting in resistance to chemoradiotherapy. However, the significance of CD44v9 in patients with lung adenocarcinoma is unknown. METHODS:We used immunohistochemical an...

journal_title：Annals of surgical oncology

authors： Akamine T,Tagawa T,Ijichi K,Toyokawa G,Takamori S,Hirai F,Okamoto T,Oda Y,Maehara Y

更新日期：2019-05-01 00:00:00

abstract：: ...

journal_title：Annals of surgical oncology

authors： Lopez-Aguiar AG,Cardona K

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:The efficacy of chemoprevention for breast cancer risk reduction has been demonstrated in randomized controlled trials; however, use remains low. We sought to determine whether uptake differed by risk factors, and to identify reasons for refusal and termination. METHODS:Women seen in a high-risk c...

journal_title：Annals of surgical oncology

authors： Flanagan MR,Zabor EC,Stempel M,Mangino DA,Morrow M,Pilewskie ML

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Performing a sentinel lymph node biopsy (SLNB) is the standard of care for axillary nodal staging in patients with invasive breast cancer and clinically negative nodes. The procedure provides valuable staging information with few complications when performed by experienced surgeons. However, variation in pro...

journal_title：Annals of surgical oncology

authors： James TA,Coffman AR,Chagpar AB,Boughey JC,Klimberg VS,Morrow M,Giuliano AE,Harlow SP

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Functional chemokine receptors are expressed in many malignant tumors, including papillary thyroid carcinoma (PTC). These receptors promote tumor growth and metastasis in response to endogenous chemokines. The purpose of this study was to examine the expression of two chemokine receptors-CXCR4 and CCR7-in a ...

journal_title：Annals of surgical oncology

authors： Wagner PL,Moo TA,Arora N,Liu YF,Zarnegar R,Scognamiglio T,Fahey TJ 3rd

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome. Up to 30% of families with HDGC have mutations in the E-cadherin gene, CDH1. The role of prophylactic versus therapeutic gastrectomy for HDGC was studied prospectively. METHODS:Eighteen consecutive patients with CDH1 mutation...

journal_title：Annals of surgical oncology

authors： Chen Y,Kingham K,Ford JM,Rosing J,Van Dam J,Jeffrey RB,Longacre TA,Chun N,Kurian A,Norton JA

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Visceral fat accumulation and muscle depletion have been identified as poor prognostic factors for various cancers. However, the significance of visceral adiposity and sarcopenic visceral obesity on outcomes after resection of pancreatic cancer remains unclear. METHODS:A retrospective analysis of 301 patien...

journal_title：Annals of surgical oncology

authors： Okumura S,Kaido T,Hamaguchi Y,Kobayashi A,Shirai H,Yao S,Yagi S,Kamo N,Hatano E,Okajima H,Takaori K,Uemoto S

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Inflammation has been demonstrated to promote cancer metastasis. Due to the well-known systemic inflammatory responses (SIR) after major surgery, it is critical to investigate and attenuate SIR-induced tumor metastasis of cancer patients suffering surgical procedures. METHODS:C57BL/6 mice were intravenously...

journal_title：Annals of surgical oncology

authors： Zhang X,Moriwaki T,Kawabata T,Goto S,Liu KX,Guo CY,Li TS

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:OncotypeDX recurrence score (RS)® has been found to predict recurrence and disease-free survival in patients with node negative breast cancer. Whether RS is useful in guiding locoregional therapy decisions is unclear. We sought to evaluate the relationship between RS and lymph node burden. METHODS:Patients ...

journal_title：Annals of surgical oncology

authors： Tevis SE,Bassett R,Bedrosian I,Barcenas CH,Black DM,Caudle AS,DeSnyder SM,Fitzsullivan E,Hunt KK,Kuerer HM,Lucci A,Meric-Bernstam F,Mittendorf EA,Park K,Teshome M,Thompson AM,Hwang RF

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Melanoma that involves the upper gastrointestinal (GI) tract is rare and studies relating to endoscopic and pathologic findings with clinical outcomes are lacking. We reviewed the gross and microscopic patterns of the upper GI tract in primary and metastatic melanoma, and examined their association with clin...

journal_title：Annals of surgical oncology

authors： Ahn JY,Hwang HS,Park YS,Kim HR,Jung HY,Kim JH,Lee SE,Kim MA

更新日期：2014-08-01 00:00:00

abstract：INTRODUCTION:The moderate-penetrance germline mutations ATM, CHEK2, and PALB2 are implicated in an increased risk of the development of breast cancer. Whether these mutations provide clinical utility to guide treatment strategies and prognosis remains unknown. METHODS:A retrospective case-control study from a tertiary...

journal_title：Annals of surgical oncology

authors： Bergstrom C,Pence C,Berg J,Partain N,Sadeghi N,Mauer C,Pirzadeh-Miller S,Gao A,Li H,Unni N,Syed S

更新日期：2020-09-29 00:00:00

abstract：BACKGROUND:Experimental studies have revealed that D2-40 is useful in identifying the presence of lymphatic invasion in various malignant neoplasms, but the clinical significance remains unclear. The purpose of this study is to assess the clinical significance of D2-40 status in completely resected non-small cell lung ...

journal_title：Annals of surgical oncology

authors： Iwakiri S,Nagai S,Katakura H,Takenaka K,Date H,Wada H,Tanaka F

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Surgery is the most important treatment for nonmetastatic breast cancer; however, the utilization of modern surgical techniques in management of breast cancer in mainland China has not been reported. METHODS:The medical records of 5887 consecutive breast cancer patients treated surgically in the past 16 yea...

journal_title：Annals of surgical oncology

authors： Yu KD,Di GH,Wu J,Lu JS,Shen KW,Shen ZZ,Shao ZM

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:Guidelines for screening mammography have been established by numerous medical societies. Guidelines have not been established for follow-up mammography for patients who have been treated with breast-conserving surgery. Many radiologists recommend mammography of the treated breast 6 months after completion...

journal_title：Annals of surgical oncology

authors： Lewis JL,Tartter PI

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Hospitalization is associated with negative clinical effects that last beyond discharge. This study aimed to determine whether hospitalization in the year before major oncologic surgery is associated with adverse outcomes. METHODS:Patients 18 years of age or older with stomach, pancreas, colon, or rectal ca...

journal_title：Annals of surgical oncology

authors： Sharoky CE,Collier KT,Wirtalla CJ,Sinnamon AJ,Neuwirth MG,Kuo LE,Roses RE,Fraker DL,Karakousis GC,Kelz RR

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:The standard treatment for patients 75 years of age or younger with cStage 2 or 3 esophageal cancer is preoperative chemotherapy followed by esophagectomy. The optimal treatment for elderly patients, especially those considered vulnerable, remains unclear. METHODS:This study retrospectively reviewed the dat...

journal_title：Annals of surgical oncology

authors： Booka E,Haneda R,Ishii K,Tsushima T,Yasui H,Tsubosa Y

更新日期：2020-09-02 00:00:00

abstract：BACKGROUND:Noninvasive thermal ablation using magnetic resonance (MR)-guided focused ultrasound (MRgFUS) has been shown to be clinically effective in uterine fibroids, and is being evaluated for ablation of breast, liver, and brain lesions. Recently MRgFUS has been evaluated for palliation of pain caused by bone metast...

journal_title：Annals of surgical oncology

authors： Liberman B,Gianfelice D,Inbar Y,Beck A,Rabin T,Shabshin N,Chander G,Hengst S,Pfeffer R,Chechick A,Hanannel A,Dogadkin O,Catane R

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:In several neoplastic diseases, including breast cancer, immunosuppression correlates with disease stage, progression, and outcome. Thus, thorough analysis of immune parameters in breast cancer patients may be beneficial in designing effective anticancer immune-based therapies. METHODS:We investigated dendr...

journal_title：Annals of surgical oncology

authors： Pockaj BA,Basu GD,Pathangey LB,Gray RJ,Hernandez JL,Gendler SJ,Mukherjee P

更新日期：2004-03-01 00:00:00

abstract：:Isolated hepatic perfusion (IHP) is a proven approach for regional delivery of chemotherapy in patients with unresectable primary and metastatic tumors of the liver. Most trials of IHP have utilized melphalan as the active drug in the perfusate. We performed a phase I trial to evaluate the efficacy, safety, and maximu...

journal_title：Annals of surgical oncology

authors： Zeh HJ 3rd,Brown CK,Holtzman MP,Egorin MJ,Holleran JL,Potter DM,Bartlett DL

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:The rate of contralateral prophylactic mastectomy (CPM) has recently increased. The aim of this study is to assess perceptions of contralateral breast cancer (CBC) risk among breast cancer patients and to evaluate tumor and patient factors associated with risk perception. METHODS:We conducted a prospectiv...

journal_title：Annals of surgical oncology

authors： Abbott A,Rueth N,Pappas-Varco S,Kuntz K,Kerr E,Tuttle T

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Lymph node involvement is a very important prognostic factor for cutaneous melanoma. In this paper we try to validate a nomogram that was created at the Memorial Sloan-Kettering Cancer Center, New York, to predict the probability of metastases in the sentinel nodes of patients with cutaneous melanoma. METHO...

journal_title：Annals of surgical oncology

authors： Piñero A,Canteras M,Ortiz E,Martínez-Barba E,Parrilla P

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:The role of supplemental oxygen therapy in the healing of esophagojejunal anastomosis is still very much in an experimental stage. The aim of the present prospective, randomized study was to assess the effect of administration of perioperative supplemental oxygen therapy on esophagojejunal anastomosis, where...

journal_title：Annals of surgical oncology

authors： Schietroma M,Cecilia EM,Carlei F,Sista F,De Santis G,Piccione F,Amicucci G

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Growing evidence suggests that the tumor immune microenvironment influences breast cancer development and prognosis. Density of tumor-infiltrating lymphocytes (TILs) within invasive breast cancer is correlated with response to therapy, especially in triple-negative disease. The clinical relevance and outcome...

journal_title：Annals of surgical oncology

authors： Darvishian F,Ozerdem U,Adams S,Chun J,Pirraglia E,Kaplowitz E,Guth A,Axelrod D,Shapiro R,Price A,Troxel A,Schnabel F,Roses D

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the accuracy of breast magnetic resonance imaging (MRI) to predict residual lesion size after neoadjuvant chemotherapy (NAC) and to determine the factors that influence the accuracy of response prediction. METHODS:This study comprised 166 patients who underwent MRI bef...

journal_title：Annals of surgical oncology

authors： Ko ES,Han BK,Kim RB,Ko EY,Shin JH,Hahn SY,Nam SJ,Lee JE,Lee SK,Im YH,Park YH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The value of p53 status for predicting response to chemotherapy-based treatment in patients with esophageal cancer has been controversial. We conducted a meta-analysis to elucidate the correlation of p53 status with the response to chemotherapy-based treatment. METHODS:Studies were searched in PubMed, Embas...

journal_title：Annals of surgical oncology

authors： Zhang SS,Huang QY,Yang H,Xie X,Luo KJ,Wen J,Cai XL,Yang F,Hu Y,Fu JH

更新日期：2013-07-01 00:00:00