Abstract：
:The objective of this study was to systematically assess the effects of pharyngeal anatomical details on breathing resistance and acoustic characteristics by means of computational modeling. A physiologically realistic nose-throat airway was reconstructed from medical images. Individual airway anatomy such as the uvula, pharynx, and larynx was then isolated for examination by gradually simplifying this image-based model geometry. Large eddy simulations with the FW-H acoustics model were used to simulate airflows and acoustic sound generation with constant flow inhalations in rigid-walled airway geometries. Results showed that pharyngeal anatomical details exerted a significant impact on breathing resistance and energy distribution of acoustic sound. The uvula constriction induced considerably increased levels of pressure drop and acoustic power in the pharynx, which could start and worsen snoring symptoms. Each source anatomy was observed to generate a unique spectrum with signature peak frequencies and energy distribution. Moreover, severe pharyngeal airway narrowing led to an upward shift of sound energy in the high-frequency range. Results indicated that computational aeroacoustic modeling appeared to be a practical tool to study breathing-related disorders. Specifically, high-frequency acoustic signals might disclose additional clues to the mechanism of apneic snoring and should be included in future acoustic studies.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Xi J,Si X,Kim J,Su G,Dong Hdoi
10.1007/s11517-014-1160-zsubject
Has Abstractpub_date
2014-07-01 00:00:00pages
567-77issue
7eissn
0140-0118issn
1741-0444journal_volume
52pub_type
杂志文章abstract：:A generic framework for the automated classification of human movements using an accelerometry monitoring system is introduced. The framework was structured around a binary decision tree in which movements were divided into classes and subclasses at different hierarchical levels. General distinctions between movements...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02347551
更新日期：2004-09-01 00:00:00
abstract：:Leukaemia is a type of blood cancer which mainly occurs when bone marrow produces excess white blood cells in our body. This disease not only affects adult but also is a common cancer type among children. Treatment of leukaemia depends on its type and how far the disease has spread in the body. Leukaemia is classified...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-020-02282-x
更新日期：2020-12-01 00:00:00
abstract：:Detailed finite element (FE) models are used as promising tools to investigate traumatic brain injuries, although their accuracy is strongly dependent on the characterization of the mechanical behaviors of the different anatomic structures in the brain. In some cases, when the FE models require finer spatial resolutio...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-018-1891-3
更新日期：2019-03-01 00:00:00
abstract：:The visco-elastic properties of living cells, measured to date by various authors, vary considerably, depending on the experimental methods and/or on the theoretical models used. In the present study, two mechanisms thought to be involved in cellular visco-elastic responses were analysed, based on the idea that the cy...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02349982
更新日期：2003-11-01 00:00:00
abstract：:A nonlinear prediction method for investigating the dynamic interdependence between short length time series is presented. The method is a generalization to bivariate prediction of the univariate approach based on nearest neighbor local linear approximation. Given the input and output series x and y, the relationship ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-006-0043-3
更新日期：2006-05-01 00:00:00
abstract：:A comparison of auditory and visual perception of scatterplots showed similar correlation estimation performance in both modalities. The present study replicated this experiment using electrotactile (electrocutaneous) presentation of scatterplots on the fingertips and abdomen, as well as visual presentation. The corre...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345967
更新日期：2005-03-01 00:00:00
abstract：:It is proposed that myo-electric signals can be used to augment conventional speech-recognition systems to improve their performance under acoustically noisy conditions (e.g. in an aircraft cockpit). A preliminary study is performed to ascertain the presence of speech information within myo-electric signals from facia...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345373
更新日期：2001-07-01 00:00:00
abstract：:The object of this study is to compare the performance of two new bilinear time-frequency representation techniques with the spectrogram to characterise the behaviour of heart murmurs produced by bioprosthetic heart valves implanted in the mitral or aortic position. The murmurs are those of mitral stenosis, mitral reg...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02525526
更新日期：1997-09-01 00:00:00
abstract：:Transcranial magnetic stimulation (TMS) allows the assessment of stroke patients' cortical excitability and corticospinal tract integrity, which provide information regarding motor function recovery. However, the extraction of features from motor-evoked potentials (MEP) elicited by TMS, such as amplitude and latency, ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-021-02315-z
更新日期：2021-01-26 00:00:00
abstract：:This study describes a new method for analyzing microcirculatory videos. It introduces algorithms for quantitative assessment of vessel length, diameter, the functional microcirculatory density distribution and red blood-cell (RBC) velocity in individual vessels as well as its distribution. The technique was validated...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-008-0349-4
更新日期：2008-07-01 00:00:00
abstract：:The aim of this study was the analysis of the mechanical behaviour of a partially porous lumbar custom-made cage by means of a subject-specific finite element analysis (FEA). The cage, made of Ti6Al4V ELI alloy, was produced via electron beam melting (EBM) process and surgically implanted in a female subject, 50 years...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-019-02078-8
更新日期：2019-12-01 00:00:00
abstract：:Conduct disorder (CD) is an important mental health problem in childhood and adolescence. There is presently a trend of revealing neural mechanisms using measures of brain networks. This study goes further by presenting a classification scheme to distinguish subjects with CD from typically developing healthy subjects ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-020-02215-8
更新日期：2020-09-01 00:00:00
abstract：:Variations in the amplitude and period of essential and Parkinsonian tremors were studied. It was found that the variations in frequency (or period) were mostly similar to the white noise, with the standard deviation typically less than 10% of the mean, whereas the variations in amplitude were much larger, with standa...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02344710
更新日期：2004-05-01 00:00:00
abstract：:A hypothetical neuromusculoskeletal model is developed to simulate human normal walking and its modulated behaviors. A small set of neural periodic patterns drive spinal muscle synergies which in turn lead to specific pattern of muscle activation and supraspinal feedback systems maintain postural balance during walkin...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-007-0277-8
更新日期：2008-02-01 00:00:00
abstract：:The regulation of cerebral blood flow (CBF) following changes in arterial blood pressure (ABP) and end-tidal pCO2 (EtCO2) are of clinical interest in assessing cerebrovascular reserve capacity. Linear finite-impulse-response modelling is applied to ABP, EtCO2 and CBF velocity (CBFV, from transcranial Doppler measureme...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345749
更新日期：2000-09-01 00:00:00
abstract：:A computer-aided method was developed to automatically localize tumors in lung PET images of discrete bins within the breathing cycle, followed by an algorithm that registers all the information of a complete respiratory cycle into a single reference bin. Four registration/integration algorithms: Centroid Based, Inten...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-009-0549-6
更新日期：2010-01-01 00:00:00
abstract：:In vivo follow-up of muscle shape variation represents a challenge when evaluating muscle development due to disease or treatment. Recent developments in muscles reconstruction techniques indicate MRI as a clinical tool for the follow-up of the thigh muscles. The comparison of 3D muscles shape from two different seque...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-015-1302-y
更新日期：2015-10-01 00:00:00
abstract：:Quantitative sensory testing (QST) can provide useful information about the underlying mechanisms involved in chronic pain. However, currently available devices typically employed suffer from operator-dependent effects, or are too cumbersome for routine clinical care. This paper presents the design and initial validat...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-013-1033-x
更新日期：2013-06-01 00:00:00
abstract：:The clinical efficacy of a microwave (MW) hyperthermia system using an electric-field converging (lens) applicator is evaluated for 42 malignant tumours with a maximum tumour depth of less than 7 cm. The mean of the maximum, average and minimum tumour temperature of the 42 tumours are 44.5, 42.5 and 40.7 C, respective...
journal_title：Medical & biological engineering & computing
pub_type： 临床试验,杂志文章
doi：10.1007/BF02522944
更新日期：1995-01-01 00:00:00
abstract：:A simple inertial measurement unit (IMU) incorporating rate gyroscopes and accelerometers has been tested to investigate the trunk kinematics during the sit-to-stand. It was affixed at trunk L5 level and used for sit-to-stand position and orientation reconstruction. The method was validated with standard optoelectroni...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-007-0224-8
更新日期：2007-10-01 00:00:00
abstract：:The development of computer technology now allows the quick and efficient automatic fluorescence microscopy generation of a large number of images of proteins in specific subcellular compartments using fluorescence microscopy. Digital image processing and pattern recognition technology can easily classify these images...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-018-01946-z
更新日期：2019-06-01 00:00:00
abstract：:Marfan syndrome (MFS) is a genetic disorder that affects connective tissue, impairing cardiovascular structures and function, such as heart valves and aorta. Thus, patients with Marfan disease have a higher risk of developing circulatory problems associated with mitral and aortic valves prolapse, manifested as dilated...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-016-1524-7
更新日期：2017-03-01 00:00:00
abstract：:The aim of this work is to quantify individual and regional differences in the relative concentration of gamma-aminobutyric acid (GABA) in human brain with in vivo magnetic resonance spectroscopy. Spectral editing Mescher-Garwood point resolved spectroscopy (MEGA-PRESS) sequence and GABA analysis toolkit (Gannet) were...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-016-1579-5
更新日期：2017-06-01 00:00:00
abstract：:An eye pointer was developed as a new line-of-sight displacement analyser. It analyses an observer's eye movements and superimposes their line of vision on a TV image which is the same as their view. A newly developed miniature colour field camera and very compact eye-movement sensors are attached to a translucent rei...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02446149
更新日期：1990-07-01 00:00:00
abstract：:The aim of this study was to develop a radiation-free method to measure gastric emptying. Such a method would be useful e.g. for patients who need repeated measurements and in pregnancy. Ferrimagnetic particles (gamma-Fe2O3), ingested within a solid test meal (pancakes), were magnetised by an applied magnetic field. A...
journal_title：Medical & biological engineering & computing
pub_type： 临床试验,杂志文章
doi：10.1007/BF02522849
更新日期：1998-01-01 00:00:00
abstract：:A three-dimensional model of myocardial tissue has been developed which incorporates electrotonic interactions between neighbouring myocytes. The algorithms of the model are based on asynchronous planning of discrete events. Each cellular element is described in a logical way and traces a predefined action potential w...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02441665
更新日期：1991-07-01 00:00:00
abstract：:We present a novel method to iteratively calculate discrete Fourier transforms for discrete time signals with sample time intervals that may be widely nonuniform. The proposed recursive Fourier transform (RFT) does not require interpolation of the samples to uniform time intervals, and each iterative transform update ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-009-0461-0
更新日期：2009-07-01 00:00:00
abstract：:Dengue fever detection and classification have a vital role due to the recent outbreaks of different kinds of dengue fever. Recently, the advancement in the microarray technology can be employed for such classification process. Several studies have established that the gene selection phase takes a significant role in ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-017-1722-y
更新日期：2018-04-01 00:00:00
abstract：:Pain control in conscious patients was investigated using a push-button, demand-driven supply of drugs. A fuzzy logic patient-controlled analgesia (PCA) algorithm was compared with a conventional algorithm, for alfentanil administration in extracorporeal shock-wave lithotripsy. The conventional PCA algorithm used an i...
journal_title：Medical & biological engineering & computing
pub_type： 临床试验,杂志文章
doi：10.1007/BF02347706
更新日期：2002-01-01 00:00:00
abstract：:Bone mass and microarchitecture are the main determinants of bone strength. Three-dimensional micro-computed tomography has the potential to examine complete bones of small laboratory animals with very high resolution in a non-invasive way. In the presented work, the proximal part of the tibiae of hindlimb unloaded an...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02347054
更新日期：2000-05-01 00:00:00
