Abstract：
:A three-dimensional model of myocardial tissue has been developed which incorporates electrotonic interactions between neighbouring myocytes. The algorithms of the model are based on asynchronous planning of discrete events. Each cellular element is described in a logical way and traces a predefined action potential which is dynamically modified depending on the electrotonic interactions. The model has a low computational complexity and has been implemented on personal workstations even for experiments investigating arrhythmogenic processes and simulating several tens of cycles in blocks composed of several thousand elements. The paper describes the algorithmic implementation of the model and presents three series of experiments examining the dependence of the accuracy of the model on the size of the modelled tissue, changes of the shape of simulated T-waves due to electrotonic interactions and arrhythmogenic processes caused by lowering the threshold of the electric flow which excites individual cells.
journal_name
Med Biol Eng Computjournal_title
Medical & biological engineering & computingauthors
Malik M,Camm AJdoi
10.1007/BF02441665subject
Has Abstractpub_date
1991-07-01 00:00:00pages
425-32issue
4eissn
0140-0118issn
1741-0444journal_volume
29pub_type
杂志文章abstract：:The long QT syndrome (LQTS) is a genetic disorder, typically characterized by a prolonged QT interval in the ECG due to abnormal cardiac repolarization. LQTS may lead to syncopal episodes and sudden cardiac death. Various parameters based on T-wave morphology, as well as the QT interval itself have been shown to be us...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-006-0061-1
更新日期：2006-07-01 00:00:00
abstract：:It is of great importance to effectively process and interpret surface electromyogram (sEMG) signals to actuate a robotic and prosthetic exoskeleton hand needed by hand amputees. In this paper, we have proposed a cepstrum analysis-based method for classification of basic hand movement sEMG signals. Cepstral analysis t...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-019-02024-8
更新日期：2019-10-01 00:00:00
abstract：:The present study describes a new methodological approach which allows the separate analysis and quantitative determination of the viscous and elastic components of human hair using a computerised experimental system. In a first series of experiments subsequent to the estimation of the cross-sectional surface area of ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02446198
更新日期：1992-01-01 00:00:00
abstract：: ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章,撤回出版物
doi：10.1007/s11517-018-1933-x
更新日期：2019-03-01 00:00:00
abstract：:Sino-aortic denervation (SAD) is employed in cats to evaluate the baroreflex influence on blood pressure (BP) and pulse interval (PI) spectral components from 0.00008 to 0.9 Hz as assessed by FFT wide-band spectra and their 1/f modelling; and the linear coupling between BP and PI and between systolic and diastolic BP ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02520018
更新日期：1996-03-01 00:00:00
abstract：:An efficient and novel modeling approach is proposed in this paper for identifying proteins or genes involved in melanoma skin cancer. Two types of classifiers are modeled, based on the chemical structure and hydropathy property of amino acids. These classifiers are further implemented using NI LabVIEW-based hardware ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-020-02241-6
更新日期：2020-10-01 00:00:00
abstract：:Nowadays, acoustic emission (AE) has its applications in various areas, including mechanical, civil, underwater acoustics, and biomedical engineering. It is a non-destructive evaluation (NDE) and a non-intrusive method to detect active damage mechanisms such as crack growth, delamination, and processes such as frictio...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章,评审
doi：10.1007/s11517-020-02202-z
更新日期：2020-08-01 00:00:00
abstract：:Taking advantage of motion sensing technology, a quantitative assessment method for lower limbs motor function of cerebral palsy (CP) based on the gross motor function measurement (GMFM)-24 scale was explored in this study. According to the motion analysis on GMFM-24 scale, we translated the assessment problem of GMFM...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-019-02076-w
更新日期：2020-01-01 00:00:00
abstract：:This work addresses the problem of estimating the conduction velocity (CV) of single motor unit (MU) action potentials from surface EMG signals detected with linear electrode arrays during voluntary muscle contractions. In ideal conditions, that is without shape or scale changes of the propagating signals and with add...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02344807
更新日期：2001-03-01 00:00:00
abstract：:Cardiac resynchronization therapy (CRT) with biventricular pacing (BV) is an established therapy for heart failure (HF) patients with inter- and intraventricular conduction delay. The aim of this pilot study was to test the feasibility of both transesophageal measurement of left ventricular (LV) electrical delay and t...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-011-0767-6
更新日期：2011-08-01 00:00:00
abstract：:This review is a commentary on recent, altered perspectives about biomedical engineering and its role in medicine. It is argued that, rather than being a peripheral specialty, medical engineering and engineering principles in general have a direct application to biochemical medicine and cell biology. A brief descripti...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章,评审
doi：10.1007/BF02446170
更新日期：1992-07-01 00:00:00
abstract：:The development of an active implantable device for measuring electrocardiogram (ECG) is presented. The study is a part of a project which aims at developing implantable ECG instrumentation with wireless data and power transfer ( http://www.ele.tut.fi/tule ). The developed implant presented here has all the measuremen...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章,评审
doi：10.1007/s11517-007-0264-0
更新日期：2007-12-01 00:00:00
abstract：:In the PREVENIR-5 study, artificial neural networks (NN) were applied to a large sample of patients with recent first acute coronary syndrome (ACS) to identify determinants of persistence of evidence-based cardiovascular medications (EBCM: antithrombotic + beta-blocker + statin + angiotensin converting enzyme inhibito...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-011-0785-4
更新日期：2011-08-01 00:00:00
abstract：:The purpose of the present study is to analyze the prognostic factors of acute leukemia and to construct a decision model based on a causal relationship between the factors of this disease to assist medical specialists. In medical decisions, to reach effective, quick, and reliable results, there is a need for a simple...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-020-02267-w
更新日期：2020-11-01 00:00:00
abstract：:A computer-controlled pump for use both in the study of vascular haemodynamics and in the calibration of clinical devices which measure blood flow is designed. The novel design of this pump incorporates two rack-mounted pistons, driven into opposing cylinders by a micro-stepping motor. This approach allows the product...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02446086
更新日期：1991-11-01 00:00:00
abstract：:When the microvascular blood perfusion in human skin is measured by photoplethysmography (PPG), infra-red light (800-960 nm) is normally used as the light source. The PPG signal, which consists of a pulsatile (AC) and a slowly fluctuating (DC) component, was studied at different optical wavelengths utilising optical f...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02446295
更新日期：1991-01-01 00:00:00
abstract：:The aim of this study was to investigate conventionally and early loaded titanium and titanium-zirconium alloy implants by three-dimensional finite element stress analysis. Three-dimensional model of a dental implant was created and a thread area was established as a region of interest in trabecular bone to study a lo...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-015-1256-0
更新日期：2015-05-01 00:00:00
abstract：:Hepatic echinococcosis (HE) is a life-threatening liver disease caused by parasites that requires a precise diagnosis and proper treatments. To assess HE lesions accurately, we propose a novel automatic HE lesion segmentation and classification network that contains lesion region positioning (LRP) and lesion region se...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-020-02126-8
更新日期：2020-03-01 00:00:00
abstract：:The recording of sounds over the orbit of the eye has been found to be useful in the detection of intracranial aneurysms. A hydrophone for auscultation over the eye has been developed and is tested under controlled conditions. The tests consist of measurement over the eyes in three healthy volunteers at rest, during v...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02523031
更新日期：1995-03-01 00:00:00
abstract：:Deep brain stimulation (DBS) surgery is extensively used in the treatment of movement disorders. Nevertheless, methods to evaluate the clinical response during intraoperative stimulation tests to identify the optimal position for the implantation of the chronic DBS lead remain subjective. In this paper, we describe a ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-016-1559-9
更新日期：2017-05-01 00:00:00
abstract：:Measurements of the dielectric properties of healthy and atherosclerotic human artery tissues were made in the frequency range of 100 Hz-100 kHz and temperatures from 22 to 260 degrees C. The temperature dependencies of the dielectric parameters for healthy tissues reveal distinctively the temperature ranges correspon...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-007-0181-2
更新日期：2007-06-01 00:00:00
abstract：:We introduce a novel method for an automatic classification of subjects to those with or without neuromuscular disorders. This method is based on multiscale entropy of recorded surface electromyograms (sEMGs) and support vector classification. The method was evaluated on a single-channel experimental sEMGs recorded fr...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-010-0629-7
更新日期：2010-08-01 00:00:00
abstract：:A process is described for the fabrication of silicon-based microelectrodes for neurophysiology using bonded and etched-back silicon-on-insulator (BESOI) wafers. The probe shapes are defined without high levels of boron doping in the silicon; this is considered as a step towards producing probes with active electronic...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02344773
更新日期：2000-03-01 00:00:00
abstract：:Steady-state visual evoked potentials (SSVEPs) are widely employed in brain-computer interface (BCI) applications, especially to control machines. However, the use of SSVEPs leads to eye fatigue and causes lower accuracy over the long term, particularly when multi-commands are required. Therefore, this paper proposes ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-016-1560-3
更新日期：2017-06-01 00:00:00
abstract：:The magnitude, mismatch and temporal variations of the electrode-gel-skin interface impedance can cause problems in electrical impedance tomography (EIT) measurement. It is shown that at the high frequencies generally encountered in EIT the capacitive properties of the electrode interface, and especially those of the ...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章,评审
doi：10.1007/BF02523842
更新日期：1996-11-01 00:00:00
abstract：:Impedance cardiography is a low-cost noninvasive technique, based on monitoring of the thoracic impedance, for estimation of stroke volume (SV). Impedance cardiogram (ICG) is the negative of the first derivative of the impedance signal. A technique for beat-to-beat SV estimation using impedance cardiography and artifi...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-017-1752-5
更新日期：2018-06-01 00:00:00
abstract：:Respiratory sinus arrhythmia (RSA) is the variation of heart rate (or RR interval) in phase with respiration and has been extensively studied. However, the effect of respiration on atrioventricular conduction delay (and hence PR interval length) has not yet received much attention. This work reports on measurements of...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02345298
更新日期：2002-11-01 00:00:00
abstract：:The aim of the study was to compare experimentally conduction velocity (CV) estimates obtained with different estimation methods based on surface electromyogram (EMG) signals detected using five spatial filters. The filters investigated were the longitudinal single and double differential, transverse single and double...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/BF02348440
更新日期：2003-05-01 00:00:00
abstract：:Remote patient monitoring should reduce mortality rates, improve care, and reduce costs. We present an overview of the available technologies for the remote monitoring of chronic obstructive pulmonary disease (COPD) patients, together with the most important medical information regarding COPD in a language that is ada...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章,评审
doi：10.1007/s11517-018-1798-z
更新日期：2018-04-01 00:00:00
abstract：:In a computer-aided diagnosis (CAD) system, especially for chest radiograph or chest X-ray (CXR) screening, CXR image view information is required. Automatically separating CXR image view, frontal and lateral can ease subsequent CXR screening process, since the techniques may not equally work for both views. We presen...
journal_title：Medical & biological engineering & computing
pub_type： 杂志文章
doi：10.1007/s11517-018-1786-3
更新日期：2018-08-01 00:00:00
