Biventricular diastolic function assessed by Doppler echocardiogram in children vertically infected with human immunodeficiency virus.

Abstract:

OBJECTIVE:to determine, by Doppler-echocardiography, the frequency of cardiac diastolic dysfunction in asymptomatic and clinically stable pediatric patients with vertical infection by the human immunodeficiency virus (HIV), from the cardiovascular viewpoint. METHODS:this was an observational, prospective, and cross-sectional study, performed at a regional referral clinic for patients with HIV, in a convenience sample of 94 individuals, assessing biventricular diastolic function by Doppler-echocardiography, and weight, blood hemoglobin, and percentage of lymphocytes T-CD4(+). RESULTS:fifty patients had diastolic dysfunction. Left ventricular dysfunction occurred in 38.7%, and the predominant type of dysfunction was decreased myocardial compliance. Right ventricular dysfunction was observed in 29.4% of the sample, and abnormal relaxation was the most prevalent type. Simultaneous biventricular dysfunction occurred in 14.1% of the individuals. There was no association between dysfunction and the immune status. CONCLUSIONS:diastolic dysfunction occurred, individually or simultaneously, with no association with immune status; decreased myocardial compliance was predominant in the left ventricle, and abnormal relaxation in the right ventricle.

journal_name

J Pediatr (Rio J)

journal_title

Jornal de pediatria

authors

Silva ML,Nassar SM,Silva AP,Ponce LL,Pires MM

doi

10.1016/j.jped.2014.01.004

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

403-7

issue

4

eissn

0021-7557

issn

1678-4782

pii

S0021-7557(14)00032-1

journal_volume

90

pub_type

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