Effects of transforming growth factor β2 and connective tissue growth factor on induction of epithelial mesenchymal transition and extracellular matrix synthesis in human lens epithelial cells.

abstract：AIM:To explore the roles of phospholipids and sphingolipids in the inflammatory process of uveitis. METHODS:Aqueous humor (AH) and the retina were obtained from endotoxin-induced uveitis (EIU) rats during the acute inflammation stage (24h after endotoxin injection). Lipids were extracted using a modified Bligh and Dye...

journal_title：International journal of ophthalmology

authors： Wang HY,Wang Y,Zhang Y,Wang J,Xiong SY,Sun Q

更新日期：2018-05-18 00:00:00

abstract：AIM:To compare the optic disc blood flow of non-arteritic ischemic optic neuropathy (NAION) eyes with normal eyes. METHODS:The optic disc blood flow densities of diagnosed non-acute phase NAION eyes (21 eyes, 14 individuals) and normal eyes (19 eyes, 12 individuals) were detected via Optovue optical coherence tomograp...

journal_title：International journal of ophthalmology

authors： Ling JW,Yin X,Lu QY,Chen YY,Lu PR

更新日期：2017-09-18 00:00:00

abstract：AIM:To construct functional human full-thickness corneal replacements. METHODS:Acellular porcine corneal matrix (APCM) was developed from porcine cornea by decellulariztion. The biomechanical properties of anterior-APCM (AAPCM) and posterior-APCM (PAPCM) were checked using uniaxial tensile testing. Human corneal cells...

journal_title：International journal of ophthalmology

authors： Zhang K,Ren XX,Li P,Pang KP,Wang H

更新日期：2019-03-18 00:00:00

abstract：AIM:To identify the 100 most cited papers in cataract surgery, we performed a comprehensive bibliometric analysis basing on the literature search on the Thomson Reuters Web of Knowledge. METHODS:The number of citations, including the total citations, latest 5y citations and average citation number per year (ACY), auth...

journal_title：International journal of ophthalmology

authors： Lin ZN,Chen J,Zhang Q,Li Q,Cai MY,Yang H,Cui HP

更新日期：2017-10-18 00:00:00

abstract：AIM:To prove anthrax lethal toxin (LeTx) blocks the mitogen activated protein kinases (MAPKs) activation by degrading the MAPK/ERK kinases (MEKs) to suppress vascular endothelial growth factor (VEGF) secretion. METHODS:Human adult retinal pigmented epithelium (ARPE) cells were cultured and treated with normal glucose,...

journal_title：International journal of ophthalmology

authors： Zhang WW,Wang X,Xie P,Yuan ST,Liu QH

更新日期：2015-06-18 00:00:00

abstract：:There are many vision threatening diseases of the eye affecting millions of people worldwide. In this article, we are summarizing potential role of various matrix metalloproteinases (MMPs); the Zn (2+)-dependent endoproteases in eye health along with pathogenesis of prominent ocular diseases such as macular degenerati...

journal_title：International journal of ophthalmology

authors： Singh M,Tyagi SC

更新日期：2017-08-18 00:00:00

abstract：AIM:To investigate the efficacy of non-buckled vitrectomy with classical endotamponade agents in the treatment of primary retinal detachment (RD) complicated by inferior breaks and proliferative vitreoretinophathy (PVR). METHODS:A retrospective, consecutive and case series study of 40 patients with inferior break RD a...

journal_title：International journal of ophthalmology

authors： Sheng Y,Sun W,Mo B,Yu YJ,Gu YS,Liu W

更新日期：2012-01-01 00:00:00

abstract：AIM:To evaluate the effect of incision types for Artisan phakic intraocular lens (PIOL) implantation on ocular higher-order aberrations (HOAs). METHODS:A retrospective review was conducted of the patients who had undergone Artisan PIOL implantation for the correction of myopia and followed up for at least 6mo. Patient...

journal_title：International journal of ophthalmology

authors： Park YM,Choi BJ,Lee JS

更新日期：2016-12-18 00:00:00

abstract：AIM:To evaluate the visual outcomes and patient satisfaction of two multifocal intraocular lens implantation patterns, with the decision between the two patterns being guided by the patients' choice of visual zones that best suited their lifestyle, or lifestyle zones. METHODS:This is a prospective non-randomized compa...

journal_title：International journal of ophthalmology

authors： Lin HT,Chen WR,Ding ZF,Chen W,Wu CR

更新日期：2012-01-01 00:00:00

abstract：:Most of the ocular tumors have poor prognosis, and they remain a difficult problem in the area of ophthalmology. With the rapid development of molecular biology and immunologic techniques and the deep research on ocular tumor related genes, it becomes possible to diagnose and treat malignant tumors from the molecular ...

journal_title：International journal of ophthalmology

authors： Ning Q,Hou L,Meng M,Pan BR,Zhao XH

更新日期：2011-01-01 00:00:00

abstract：AIM:To assess the biosafety of a poly(acrylamide-co-sodium acrylate) hydrogel (PAH) as a 3D-printed intraocular lens (IOL) material. METHODS:The biosafety of PAH was first evaluated in vitro using human lens epithelial cells (LECs) and the ARPE19 cell line, and a cell counting kit-8 (CCK-8) assay was performed to inve...

journal_title：International journal of ophthalmology

authors： Li JW,Li YJ,Hu XS,Gong Y,Xu BB,Xu HW,Yin ZQ

更新日期：2020-10-18 00:00:00

abstract：AIM:To analyze the systemic factors including stroke history related to the retinal artery occlusion (RAO). METHODS:Patients with an exact diagnosis of RAO in the medical database of the Kailuan Corporation were identified as the case group. Five patients without RAO were added for each case from the Kailuan Study and...

journal_title：International journal of ophthalmology

authors： Xiao YY,Wei WB,Wang YX,Lu AD,Chen SH,Song L,Wu SL

更新日期：2020-03-18 00:00:00

abstract：AIM:To investigate the protective effect and its mechanism of lycium barbarum polysaccharides (LBP) against oxidative stress-induced apoptosis in human retinal pigment epithelial cells. METHODS:ARPE-19 cells, a human retinal pigment epithelial cell lines, were exposed to different concentrations of H2O2 for 24h, then ...

journal_title：International journal of ophthalmology

authors： Liu L,Lao W,Ji QS,Yang ZH,Yu GC,Zhong JX

更新日期：2015-02-18 00:00:00

abstract：AIM:To establish an untransfected human corneal epithelial (HCEP) cell line and characterize its biocompatibility with denuded amniotic membrane (dAM). METHODS:The torn HCEP pieces were primarily cultured in DMEM/F12 media (pH 7.2) supplemented with 20% fetal bovine serum and other necessary factors, yielding an HCEP ...

journal_title：International journal of ophthalmology

authors： Fan TJ,Xu B,Zhao J,Yang HS,Wang RX,Hu XZ

更新日期：2011-01-01 00:00:00

abstract：:We report a case of syndromic gingival fibromatosis with notable ocular lesions, bilateral congenital cataracts, esotropia, and high myopia of a 21-year-old male patient from China. The patient was diagnosed with gingival fibromatosis based on his massive gingival overgrowth and histological findings that were consist...

journal_title：International journal of ophthalmology

authors： Tang YL,Shentu XC,Zhao SJ,Tang XJ,He L,Ping FY

更新日期：2014-06-18 00:00:00

abstract：AIM:To assess the prevalence of meibomian gland dysfunction (MGD) in staffs and faculty members of Sichuan University, China. METHODS:The records of the annually systemic physical examination of 4404 consecutive staffs and faculty members of Sichuan University were analyzed retrospectively. Ocular symptoms and signs o...

journal_title：International journal of ophthalmology

authors： Gao JG,Chen J,Tang Y,Chen DN

更新日期：2020-10-18 00:00:00

abstract：:Glaucoma is the second leading cause of blindness worldwide, and also the most common optic neuropathy. The ultimate cause of vision loss in glaucoma is thought to be retinal ganglion cell (RGC) death. Neuroprotection of RGC is therefore an important goal of glaucoma therapy. Currently, glaucoma treatment relies on ph...

journal_title：International journal of ophthalmology

authors： Xiao JH,Zhang MN

更新日期：2010-01-01 00:00:00

abstract：AIM:To evaluate the neuroprotective effect of rosuvastatin, in a rat experimental glaucoma model. METHODS:Ocular hypertension was induced in right eyes of Long-Evans rats (n=30) by cauterization of three episcleral veins. Left eyes were defined as controls. Rats were divided into five groups: oral rosuvastatin, intrav...

journal_title：International journal of ophthalmology

authors： Unlu M,Aktas Z,Gocun PU,Ilhan SO,Hasanreisoglu M,Hasanreisoglu B

更新日期：2016-03-18 00:00:00

abstract：:Our aim was to report quality of life (QOL) outcomes following Xen45 Gel Stent implantation surgery in patients suffering with primary open angle glaucoma (POAG). A retrospective analysis was performed on all patients who had Xen45 implantation surgery during a 2-year period (Jun, 2016-Apr, 2018). Of 52 consecutive pa...

journal_title：International journal of ophthalmology

authors： Hassan F,Thomson LTM,Toor G,Alfahad Q

更新日期：2019-09-18 00:00:00

abstract：AIM:To investigate the impact of non-Descemet stripping endothelial keratoplasty (non-DSEK) on graft rejection rate, and its overall procedural effectiveness in patients. METHODS:Non-DSEK was performed on 65 eyes of 64 patients, and the procedural outcomes, including rejection episodes, failure and dislocation of the ...

journal_title：International journal of ophthalmology

authors： Zhang T,Li SW,Chen TH,He JL,Kang YW,Lyu FQ,Ning JH,Liu C

更新日期：2017-02-18 00:00:00

abstract：AIM:To investigate the role of fundus autofluorescence (FAF) both in the diagnosis and the preoperative and postoperative evaluation of patients with idiopathic macular hole (MH). METHODS:Forty eyes of 40 patients diagnosed as idiopathic MH between May 2010 and May 2011 were included in this retrospective study. All p...

journal_title：International journal of ophthalmology

authors： Teke MY,Cakar-Ozdal P,Sen E,Elgin U,Nalcacıoglu-Yuksekkaya P,Ozturk F

更新日期：2013-10-18 00:00:00

abstract：:Corneal neovascularization (CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme- and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article aims to discuss immu...

journal_title：International journal of ophthalmology

authors： Abdelfattah NS,Amgad M,Zayed AA

更新日期：2016-04-18 00:00:00

abstract：AIM:To investigate the proportion and characteristic of emmetropia in schoolchildren aged 6-11, especially estimate the normal value of ocular biometric parameters of emmetropia. METHODS:A population-based cross-sectional study was conducted on children aged 6-11y in Shenzhen. Totally, 2386 schoolchildren from two pri...

journal_title：International journal of ophthalmology

authors： Jiang XM,Lu YY,Han X,Tan Q,Wu JS

更新日期：2020-12-18 00:00:00

abstract：AIM:To evaluate and compare the efficacy of the astigmatic correction achieved with laser in situ keratomileusis (LASIK) in eyes with myopic astigmatism using wavefront-guided (WFG) and wavefront-optimized (WFO) ablation profiles. METHODS:Prospective study included 221 eyes undergoing LASIK: 99 and 122 eyes with low a...

journal_title：International journal of ophthalmology

authors： Khalifa MA,Alsahn MF,Shaheen MS,Pinero DP

更新日期：2017-02-18 00:00:00

abstract：AIM:To describe a novel technique of creating a landing strip within the trabecular meshwork to guide trabecular micro-bypass stent (iStent) implantation in patients who underwent phacoemulsification. METHODS:Thirty-four eyes from 30 patients who underwent iStent implantation after phacoemulsification from May 2014 to...

journal_title：International journal of ophthalmology

authors： Zheng CX,Moster MR,Gogte P,Dai Y,Manzi RS,Waisbourd M

更新日期：2017-05-18 00:00:00

abstract：AIM:To evaluate the role of intravitreal ranubizumab (IVR) in the treatment of familial exudative vitreoretinopathy (FEVR) of stage 2 or greater either as primary or an ajunct to conventional treatments. METHODS:Retrospective, non-controlled clinical study. Thirty patients (37 eyes) diagnosed with FEVR were enrolled. ...

journal_title：International journal of ophthalmology

authors： Lu YZ,Deng GD,Liu JH,Yan H

更新日期：2018-06-18 00:00:00

abstract：AIM:To study the effects of curcumin on the secretion of interleukin (IL)-6 and IL-8 by corneal limbus epithelial cells. METHODS:Human corneal limbus epithelial cells were isolated and cultured from donor eyes and irradiated by UVB at different dosages with or without curcumin. MTT test was used for studying the effec...

journal_title：International journal of ophthalmology

authors： Chao SC,Hu DN,Roberts J,Shen X,Lee CY,Nien CW,Lin HY

更新日期：2017-06-18 00:00:00

abstract：AIM:To determine a relation between vitamin D level, which is an inhibitor of angiogenesis, and diabetic retinopathy and its risk factors. METHODS:In a clinic-based cross sectional study two hundred and thirty-five type 2 diabetic patients older than 20y were selected. Patients were classified according to ophthalmolo...

journal_title：International journal of ophthalmology

authors： Bonakdaran S,Shoeibi N

更新日期：2015-04-18 00:00:00

abstract：AIM:To present the rationale, design, methodology, and the baseline data of the Beijing Desheng Diabetic Eye Study (BDDES), and to determine the prevalence of diabetic retinopathy (DR) and possible risk factors in patients with type 2 diabetes mellitus (T2DM) in an urban community of Beijing, China. METHODS:Community-...

journal_title：International journal of ophthalmology

authors： Li YY,Yang XF,Gu H,Liu XP,Snellingen T,Liu NP

更新日期：2018-01-18 00:00:00

abstract：AIM:To determine the location of c-jun protein, dynamic changes in c-jun mRNA and protein expression, and ultrastructure characteristics in the rd mouse retina, following a single dose of brain-derived neurotrophic factor (BDNF) in a short period of time. METHODS:A single intravitreal injection of BDNF at two dosages ...

journal_title：International journal of ophthalmology

authors： Chen R,Yin XB,Peng CX,Li GL

更新日期：2012-01-01 00:00:00