Effect of brain-derived neurotrophic factor on c-jun expression in the rd mouse retina.

abstract：AIM:To examine the cytotoxic effect of pilocarpine, an anti-glaucoma drug, on human corneal stromal (HCS) cells and its underlying cytotoxic mechanisms using an in vitro model of non-transfected HCS cells. METHODS:After HCS cells were treated with pilocarpine at a concentration from 0.15625 g/L to 20.0 g/L, their morp...

journal_title：International journal of ophthalmology

authors： Yuan XL,Wen Q,Zhang MY,Fan TJ

更新日期：2016-04-18 00:00:00

abstract：AIM:To determine the clinical outcomes of laser in situ keratomileusis (LASIK) treatments using LaserSight AstraPro Planner 2.2 Z software for myopia with asymmetric corneal shape. METHODS:Four hundred and eighty-five eyes [243 patients; spherical equivalent (SE), -5.93±1.88 diopters (D)] were treated with asymmetric ...

journal_title：International journal of ophthalmology

authors： Liu B,Chen W,Shao DW,Wang H,Ru HX,Zhang M,Wang Y,Yang CY

更新日期：2014-06-18 00:00:00

abstract：AIM:To compare the clinical performance of two types of silicon hydrogel contact lenses used as bandage lenses after LASEK surgery. METHODS:A prospective, double-masked study was conducted on 42 eyes of 21 patients who received binocular LASEK surgeries. The interocular difference in spherical equivalent power was les...

journal_title：International journal of ophthalmology

authors： Qu XM,Dai JH,Jiang ZY,Qian YF

更新日期：2011-01-01 00:00:00

abstract：AIM:To investigate extent and nature of visual pathways involvement in children with clinically isolated syndrome (CIS). METHODS:Forty-seven patients (age 11-17y) with CIS, which later proved to be multiple sclerosis (MS) onset, and 30 controls underwent visual evoked potentials (VEP) investigation within 12d from the...

journal_title：International journal of ophthalmology

authors： Voitenkov V,Skripchenko N,Klimkin A

更新日期：2015-04-18 00:00:00

abstract：AIM:To evaluate the neuroprotective effect of rosuvastatin, in a rat experimental glaucoma model. METHODS:Ocular hypertension was induced in right eyes of Long-Evans rats (n=30) by cauterization of three episcleral veins. Left eyes were defined as controls. Rats were divided into five groups: oral rosuvastatin, intrav...

journal_title：International journal of ophthalmology

authors： Unlu M,Aktas Z,Gocun PU,Ilhan SO,Hasanreisoglu M,Hasanreisoglu B

更新日期：2016-03-18 00:00:00

abstract：AIM:To compare three initial monthly intravitreal ranibizumab (IVR) injections followed by pro re nata (PRN) dosing with one initial monthly IVR injections followed by PRN dosing for macular edema (ME) secondary to branch retinal vein occlusion (BRVO). METHODS:Forty-two eyes of 42 patients who had IVR injections for B...

journal_title：International journal of ophthalmology

authors： Bayat AH,Çakır A,Özturan ŞG,Bölükbaşı S,Erden B,Elçioğlu MN

更新日期：2018-09-18 00:00:00

abstract：AIM:To investigate the cytotoxic effect on human corneal epithelial cells (HCECs) and the ability to faciliate corneal epithelial wound healing of carboxymethylcellulose (CMC) and hyaluronic acid (HA). METHODS:HCECs were exposed to 0.5% CMC (Refresh plus(®), Allergan, Irvine, California, USA) and 0.1% and 0.3% HA (Kyn...

journal_title：International journal of ophthalmology

authors： Lee JS,Lee SU,Che CY,Lee JE

更新日期：2015-04-18 00:00:00

abstract：AIM:To investigate the effect of broccoli sprouts juice in preventing lens protein aggregation in diabetic rat model. METHODS:Totally 25 male Wistar rats were divided into negative control group, diabetic group without juice treatment as positive control and diabetic group given broccoli sprouts juice 0.25, 0.5 and 1 ...

journal_title：International journal of ophthalmology

authors： Puspitasari A,Handayani N

更新日期：2019-09-18 00:00:00

abstract：AIM:To investigate the healing process after severe corneal epithelial damage in rats treated with mesenchymal stem cells (MSCs) cultured with or without keratinocyte growth factor (KGF-2) and autologous serum (AS) on amniotic membrane (AM). Many patients are blind and devastated by severe ocular surface diseases due t...

journal_title：International journal of ophthalmology

authors： Pınarlı FA,Okten G,Beden U,Fışgın T,Kefeli M,Kara N,Duru F,Tomak L

更新日期：2014-04-18 00:00:00

abstract：AIM:To find a stable, inexpensive, and reliable method to produce a rat meibomian gland dysfunction (MGD) model. METHODS:We inserted slim guidewires into the meibomian gland orifices of twelve Brown Norway rats and fulgurized every guidewire to destroy part of the meibomian gland. We then observed the morphological ch...

journal_title：International journal of ophthalmology

authors： Dong ZY,Ying M,Zheng J,Hu LJ,Xie JY,Ma Y

更新日期：2018-07-18 00:00:00

abstract：AIM:To investigate a possible trigeminal proprioceptive-oculomotor neural pathway and explore possible synaptic connections between neurons in this pathway. Attempt to bring a new insight to mechanism of Marcus Gunn syndrome (MGS). METHODS:Anterograde and retrograde tract tracing was applied and combined with immunofl...

journal_title：International journal of ophthalmology

authors： Liang HC,Zhang JD,Luo PF,Qiao Y,Su AL,Zhang T,Zhu HN

更新日期：2018-03-18 00:00:00

abstract：AIM:To establish an untransfected human corneal epithelial (HCEP) cell line and characterize its biocompatibility with denuded amniotic membrane (dAM). METHODS:The torn HCEP pieces were primarily cultured in DMEM/F12 media (pH 7.2) supplemented with 20% fetal bovine serum and other necessary factors, yielding an HCEP ...

journal_title：International journal of ophthalmology

authors： Fan TJ,Xu B,Zhao J,Yang HS,Wang RX,Hu XZ

更新日期：2011-01-01 00:00:00

abstract：AIM:To investigate peripapillary retinal nerve fiber layer (RNFL), macula and ganglion cell layer thicknesses (GCC) in amblyopic eyes with spectral domain optical coherence tomography (SD-OCT). METHODS:Thirty six patients with a history of unilateral amblyopia and thirty two children who had emmetropia without amblyop...

journal_title：International journal of ophthalmology

authors： Firat PG,Ozsoy E,Demirel S,Cumurcu T,Gunduz A

更新日期：2013-01-01 00:00:00

abstract：AIM:To study plasma levels of vascular endothelial growth factor (VEGF), endothelin-1(ET-1) and nitric oxide (NO) in patients with proliferative diabetic retinopathy (PDR) before and after pan-retinal photocoagulation (PRP). METHODS:Forty patients (23 females and 17 males, mean age 48.5±12.2 years) with PDR without pr...

journal_title：International journal of ophthalmology

authors： Mohamed TA,Mohamed Sel-D

更新日期：2010-01-01 00:00:00

abstract：AIM:To evaluate clinical outcomes of unilateral implantation of a diffractive multifocal intraocular lens (IOL) in patients with contralateral monofocal IOL. METHODS:Twenty-two patients who already had implantation of a monofocal IOL in unilateral eye underwent implantation of a diffractive multifocal IOL in contralat...

journal_title：International journal of ophthalmology

authors： Kim JY,Lee Y,Won HJ,Jeong H,Park JH,Kim MJ,Tchah H

更新日期：2020-05-18 00:00:00

abstract：AIM:To evaluate the visual outcomes and patient satisfaction of two multifocal intraocular lens implantation patterns, with the decision between the two patterns being guided by the patients' choice of visual zones that best suited their lifestyle, or lifestyle zones. METHODS:This is a prospective non-randomized compa...

journal_title：International journal of ophthalmology

authors： Lin HT,Chen WR,Ding ZF,Chen W,Wu CR

更新日期：2012-01-01 00:00:00

abstract：AIM:To investigate the epidemiology and surgical outcomes of old canalicular laceration and analyze the variables impacting on the prognosis of reparation. METHODS:A retrospective review of all old canalicular laceration repairs from Jan. 1, 2008 to Dec. 30, 2015 was performed. Analyzed data included demographics, mec...

journal_title：International journal of ophthalmology

authors： Bai F,Tao H,Zhang Y,Wang P,Han C,Huang YF,Tao Y

更新日期：2017-06-18 00:00:00

abstract：AIM:To examine the association between the single nucleotide polymorphisms (SNPs) of matrix metalloprotease-9 (MMP-9) gene and primary angle-closure glaucoma (PACG) in a Chinese Han population. METHODS:DNA samples were extracted from peripheral-blood mononuclear cells of 214 PACG patients and 224 healthy controls. Gen...

journal_title：International journal of ophthalmology

authors： Gao XJ,Hou SP,Li PH

更新日期：2014-06-18 00:00:00

abstract：AIM:To investigate clinical characteristics of asymptomatic Terson syndrome and its clinical impact in patients with aneurysmal subarachnoid hemorrhage (SAH). METHODS:This retrospective, interventional study included 31 patients with aneurysmal SAH, and the medical records were reviewed. In addition to baseline charac...

journal_title：International journal of ophthalmology

authors： Kang HM,Cho JM,Kim SY,Choi JH

更新日期：2020-02-18 00:00:00

abstract：AIM:To observe and characterize imaging features of macular and optic disc areas in less than 60-year-old patients with early primary open angle glaucoma (POAG) by optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA), and to evaluate the diagnostic value of OCT and OCTA. METHODS:Total...

journal_title：International journal of ophthalmology

authors： Li YJ,Liu WS,Bai ZC,Cao RX,Ren HH

更新日期：2020-12-18 00:00:00

abstract：AIM:To study the histopathological changes in the retina and flash electroretinogram (F-ERG) features of ozone-treated streptozotocin (STZ)-induced diabetic rats. METHODS:Seventy male Sprague Dawley rats were grouped as follows: blank group (GB, n=10), model control group (GM, n=18), ozone group (GO3, n=19), and oxyge...

journal_title：International journal of ophthalmology

authors： Xie TY,Li Q,Chen XY

更新日期：2016-06-18 00:00:00

abstract：AIM:To evaluate the visual outcomes of simultaneous non-topography guided photorefractive keratectomy (PRK) and corneal collagen cross-linking (CXL) in eyes with keratoconus 5y after the procedure. METHODS:Prospective, interventional, non-randomized, and non-controlled case series design was used. Sixty eyes of 30 pat...

journal_title：International journal of ophthalmology

authors： Al-Amri AM

更新日期：2018-01-18 00:00:00

abstract：AIM:To compare conventional slow equilibrium cooling and directional freezing (DF) by gauze package for cryopreservation of human umbilical vein endothelial cells (HUVECs). METHODS:HUVECs were randomly assigned to conventional freezing (CF) and DF by gauze package group. The two groups of HUVECs were incubated with a ...

journal_title：International journal of ophthalmology

authors： Qi B,Ji QS,Hou GH,Li L,Cao XF,Wu J

更新日期：2014-10-18 00:00:00

abstract：AIM:To describe the complex, overlapping phenotype of four Chinese patients with inherited retinal dystrophies (IRDs) who harbored two pathogenic genes simultaneously. METHODS:This retrospective study included 4 patients affected with IRDs. Medical and ophthalmic histories were obtained, and clinical examinations were...

journal_title：International journal of ophthalmology

authors： Liu XZ,Tao TC,Qi H,Feng SN,Chen NN,Zhao L,Ma ZZ,Li GL,Yang LP

更新日期：2020-02-18 00:00:00

abstract：AIM:To evaluate the effect of age on visual and refractive results after laser in situ keratomileusis (LASIK) obtained with a mechanical microkeratome or a femtosecond laser. METHODS:Retrospective, nonrandomized, cohort study. A total of 3826 eyes were included in the study (1725 eyes treated with mechanical LASIK and...

journal_title：International journal of ophthalmology

authors： Garcia-Gonzalez M,Gros-Otero J,Rodriguez-Perez I,Rodero A,Teus MA

更新日期：2019-03-18 00:00:00

abstract：AIM:To analyze the systemic factors including stroke history related to the retinal artery occlusion (RAO). METHODS:Patients with an exact diagnosis of RAO in the medical database of the Kailuan Corporation were identified as the case group. Five patients without RAO were added for each case from the Kailuan Study and...

journal_title：International journal of ophthalmology

authors： Xiao YY,Wei WB,Wang YX,Lu AD,Chen SH,Song L,Wu SL

更新日期：2020-03-18 00:00:00

abstract：AIM:To investigate cap morphology after small-incision lenticule extraction (SMILE) and its effects on intraocular scattering. METHODS:Sixty-five eyes of 33 patients undergoing SMILE were enrolled. In addition to regular evaluation, Fourier-domain optical coherence tomography was used to investigate cap thickness at 1...

journal_title：International journal of ophthalmology

authors： Fu D,Wang L,Zhou XT,Yu ZQ

更新日期：2018-03-18 00:00:00

abstract：AIM:To investigate the published papers of ophthalmology in past ten years and explore the development of ophthalmology. METHORDS:The data of this study retrieved from Science Citation Index Expanded and downloaded online in November 2017, including all the papers with publication year from 2007-2016 were analyzed. Th...

journal_title：International journal of ophthalmology

authors： Yu ZL,Hu XY,Wang YN,Ma Z

更新日期：2017-12-18 00:00:00

abstract：AIM:To analyze the demography, presenting clinical features, spread of the disease of retinoblastoma in patients who were treated in two tertiary hospitals in Malaysia. METHODS:In this retrospective study, information of gender, age, race, presenting clinical features, findings of CT scan orbits and brain, lumbar punc...

journal_title：International journal of ophthalmology

authors： Reddy SC,Anusya S

更新日期：2010-01-01 00:00:00

abstract：AIM:To compare the efficacy and safety between laser therapy and anti-vascular endothelial growth factor (VEGF) agents intravitreal injection monotherapy in type-1 retinopathy of prematurity (ROP) and aggressive posterior retinopathy of prematurity (APROP). METHODS:A systematic literature search was performed in PubMe...

journal_title：International journal of ophthalmology

authors： Wang SD,Zhang GM,Shenzhen Screening for Retinopathy of Prematurity Cooperative Group.

更新日期：2020-05-18 00:00:00