Keratinocyte growth factor-2 and autologous serum potentiate the regenerative effect of mesenchymal stem cells in cornea damage in rats.

abstract：AIM:To investigate the effects of transforming growth factor β2 (TGF-β2) and connective tissue growth factor (CTGF) on transdifferentiation of human lens epithelial cells (HLECs) cultured in vitro and synthesis of extracellular matrix (ECM). METHODS:HLECs were treated with TGF-β2 (0, 0.5, 1.0, 5, 10µg/L) and CTGF (0, ...

journal_title：International journal of ophthalmology

authors： Pei C,Ma B,Kang QY,Qin L,Cui LJ

更新日期：2013-12-18 00:00:00

abstract：:Diabetic retinopathy (DR) is one of the most common and challenging ocular complications of diabetes mellitus. As a chronic, progressive ocular disease that poses a serious threat to vision, DR has gradually become a leading cause of blindness worldwide. Emerging evidence points to an important role of endoplasmic ret...

journal_title：International journal of ophthalmology

authors： Kong DQ,Li L,Liu Y,Zheng GY

更新日期：2018-10-18 00:00:00

abstract：AIM:To analyze proteomic and signal transduction alterations in irradiated melanoma cells. METHODS:We combined stable isotope labeling with amino acids in cell culture (SILAC) with highly sensitive shotgun tandem mass spectrometry (MS) to create an efficient approach for protein quantification. Protein-protein interac...

journal_title：International journal of ophthalmology

authors： Yan LB,Shi K,Bing ZT,Sun YL,Shen Y

更新日期：2013-06-18 00:00:00

abstract：AIM:To compare three initial monthly intravitreal ranibizumab (IVR) injections followed by pro re nata (PRN) dosing with one initial monthly IVR injections followed by PRN dosing for macular edema (ME) secondary to branch retinal vein occlusion (BRVO). METHODS:Forty-two eyes of 42 patients who had IVR injections for B...

journal_title：International journal of ophthalmology

authors： Bayat AH,Çakır A,Özturan ŞG,Bölükbaşı S,Erden B,Elçioğlu MN

更新日期：2018-09-18 00:00:00

abstract：:Retinoblastoma (RB) is the most common intraocular cancer of infancy and childhood. This cancer is initiated by mutation on RB1, the tumor suppressor gene that is responsible for the regulation of both cell cycle and gnome stability in retinal cells. Patients with a constitutional mutation on RB1 can be inherited. RB ...

journal_title：International journal of ophthalmology

authors： Luo C,Deng YP

更新日期：2013-06-18 00:00:00

abstract：AIM:To record aberrations with a corneal topographic device on the anterior surface of the cornea at different time-points prior to wearing and following discontinued use of rigid gas permeable (RGP) contact lenses. The effect of wearing RGP on the anterior surface of the cornea was discussed to provide guidance for cl...

journal_title：International journal of ophthalmology

authors： Yu Q,Wu JX,Zhang HN,Ye S,Dong SQ,Zhang CH

更新日期：2013-04-18 00:00:00

abstract：AIM:To investigate the cytotoxic effect on human corneal epithelial cells (HCECs) and the ability to faciliate corneal epithelial wound healing of carboxymethylcellulose (CMC) and hyaluronic acid (HA). METHODS:HCECs were exposed to 0.5% CMC (Refresh plus(®), Allergan, Irvine, California, USA) and 0.1% and 0.3% HA (Kyn...

journal_title：International journal of ophthalmology

authors： Lee JS,Lee SU,Che CY,Lee JE

更新日期：2015-04-18 00:00:00

abstract：AIM:To assess the biosafety of a poly(acrylamide-co-sodium acrylate) hydrogel (PAH) as a 3D-printed intraocular lens (IOL) material. METHODS:The biosafety of PAH was first evaluated in vitro using human lens epithelial cells (LECs) and the ARPE19 cell line, and a cell counting kit-8 (CCK-8) assay was performed to inve...

journal_title：International journal of ophthalmology

authors： Li JW,Li YJ,Hu XS,Gong Y,Xu BB,Xu HW,Yin ZQ

更新日期：2020-10-18 00:00:00

abstract：AIM:To compare the efficacy and safety between laser therapy and anti-vascular endothelial growth factor (VEGF) agents intravitreal injection monotherapy in type-1 retinopathy of prematurity (ROP) and aggressive posterior retinopathy of prematurity (APROP). METHODS:A systematic literature search was performed in PubMe...

journal_title：International journal of ophthalmology

authors： Wang SD,Zhang GM,Shenzhen Screening for Retinopathy of Prematurity Cooperative Group.

更新日期：2020-05-18 00:00:00

abstract：AIM:To assess and compare the impact of a daily disposable contact lens (CL) with high water content on the ocular surface and comfort of the presbyopic and non-presbyopic population after one day of use. METHODS:Totally 20 presbyopes and 30 non-presbyopes non-contact wearers were fitted with nesofilcon A CLs. CL thic...

journal_title：International journal of ophthalmology

authors： Lorente-Velázquez A,García-Montero M,Gómez-Sanz FJ,Rico Del Viejo L,Hernández-Verdejo JL,Madrid-Costa D

更新日期：2019-04-18 00:00:00

abstract：AIM:To study the effects of gender, eye side and age on anterior chamber measurements; To compare the anterior chamber parameters between glaucoma and normal subjects. METHODS:A total of 169 patients (299 eyes), of which 122 normal subjects (218 eyes), 24 cases (39 eyes) with primary angle-closure glaucoma (PACG) and ...

journal_title：International journal of ophthalmology

authors： Zou X,Duan XC,Zhong Q

更新日期：2010-01-01 00:00:00

abstract：AIM:To evaluate the effect of different lens constant optimization methods on the accuracy of intraocular lens (IOL) power calculation formulas for highly myopic eyes. METHODS:This study comprised 108 eyes of 94 consecutive patients with axial length (AL) over 26 mm undergoing phacoemulsification and implantation of a...

journal_title：International journal of ophthalmology

authors： Zhang JQ,Zou XY,Zheng DY,Chen WR,Sun A,Luo LX

更新日期：2019-06-18 00:00:00

abstract：AIM:To conduct a comparative study of effectiveness of silicone hydrogel contact lens and hydrogel contact lens, which are used in patients after laser-assisted subepithelial keratomileusis (LASEK). METHODS:Sixty-three patients (121 eyes) with a spherical equivalent ≤-5.0 D were chosen after undergoing LASEK in 2012 a...

journal_title：International journal of ophthalmology

authors： Xie WJ,Zeng J,Cui Y,Li J,Li ZM,Liao WX,Yang XH

更新日期：2015-12-18 00:00:00

abstract：AIM:To study the effect of different flap sizes on visual acuity, refractive outcomes, and aberrations after femtosecond laser for laser in situ keratomileusis (LASIK). METHODS:In each of the forty patients enrolled, 1 eye was randomly assigned to receive treatment with a 8.1mm diameter corneal flap, defined as the sm...

journal_title：International journal of ophthalmology

authors： Zhang YL,Liu L,Cui CX,Hu M,Li ZN,Cao LJ,Jing XH,Mu GY

更新日期：2013-10-18 00:00:00

abstract：AIM:To describe the clinical characteristics and late results of patients with retinopathy of prematurity (ROP) treated with "6h cryotherapy". METHODS:Out of 1252 infants screened for ROP, 52 patients were treated with temporal 6h cryotherapy from 1997 to 2005 were recalled to our clinic. Among these 23 patients were ...

journal_title：International journal of ophthalmology

authors： Cerman E,Ozarslan Ozcan D,Celiker H,Eraslan M,Sahin O,Kazokoglu H

更新日期：2016-04-18 00:00:00

abstract：AIM:To study the histopathological changes in the retina and flash electroretinogram (F-ERG) features of ozone-treated streptozotocin (STZ)-induced diabetic rats. METHODS:Seventy male Sprague Dawley rats were grouped as follows: blank group (GB, n=10), model control group (GM, n=18), ozone group (GO3, n=19), and oxyge...

journal_title：International journal of ophthalmology

authors： Xie TY,Li Q,Chen XY

更新日期：2016-06-18 00:00:00

abstract：AIM:To investigate the cross-talk between oxidative stress and the epidermal growth factor receptor (EGFR)/AKT signaling pathway in retinal pigment epithelial (RPE) cells. METHODS:Human RPE cell lines (ARPE-19 cell) were treated with different doses of epidermal growth factor (EGF) and hydrogen peroxide (H2O2). Cell v...

journal_title：International journal of ophthalmology

authors： Chen XD,Su MY,Chen TT,Hong HY,Han AD,Li WS

更新日期：2017-04-18 00:00:00

abstract：AIM:To investigate the fundus manifestations and human immunodeficiency virus (HIV) viral loads of acquired immune deficiency syndrome (AIDS) patients before and after highly active antiretroviral therapy (HAART). METHODS:This retrospective study included 21 AIDS patients (42 eyes) who presented to the Department of O...

journal_title：International journal of ophthalmology

authors： Di Y,Zhao XY,Ye JJ,Li B,Ma N

更新日期：2019-09-18 00:00:00

abstract：AIM:To analyze the systemic factors including stroke history related to the retinal artery occlusion (RAO). METHODS:Patients with an exact diagnosis of RAO in the medical database of the Kailuan Corporation were identified as the case group. Five patients without RAO were added for each case from the Kailuan Study and...

journal_title：International journal of ophthalmology

authors： Xiao YY,Wei WB,Wang YX,Lu AD,Chen SH,Song L,Wu SL

更新日期：2020-03-18 00:00:00

abstract：AIM:To analyze and identify the proteomic differences between liquefied after-cataracts and normal lenses by means of liquefied chromatography-tandem mass spectrometry (LC-MS/MS). METHODS:Three normal lenses and three liquefied after-cataracts were exposed to depolymerizing reagents to extract the total proteins. Prot...

journal_title：International journal of ophthalmology

authors： Ge JJ,Huang YS

更新日期：2017-09-18 00:00:00

abstract：AIM:To analyze the optical quality after implantation of toric intraocular lens with optical quality analysis system. METHODS:Fifty-two eyes of forty-four patients with regular corneal astigmatism of at least 1.00 D underwent implantation of AcrySof toric intraocular lens, including T3 group 19 eyes, T4 group 18 eyes,...

journal_title：International journal of ophthalmology

authors： Xiao XW,Hao J,Zhang H,Tian F

更新日期：2015-02-18 00:00:00

abstract：AIM:To determine whether intravitreal dexamethasone (DEX) implant induces posterior vitreous detachment or not. METHODS:We retrospectively reviewed 810 eyes of 405 patients who underwent intravitreal DEX implantation due to macular edema caused by diabetic and retinal venous occlusion in our clinic. The eyes having no...

journal_title：International journal of ophthalmology

authors： Alpay A

更新日期：2019-08-18 00:00:00

abstract：AIM:To develop a critical pathway for primary open angle glaucoma (POAG) diagnosis intended to be efficient, to unify criteria, reduce resource use and minimize costs to the health system. METHODS:We performed a systematic search on PubMed, Cochrane, Embase and ClinicalTrials.org databases and classified the quality o...

journal_title：International journal of ophthalmology

authors： Allocco AR,Ponce JA,Riera MJ,Magurno MG

更新日期：2017-06-18 00:00:00

abstract：AIM:To assess strabismus control and motor ocular alignment for basic exotropia surgery at 5y follow-up. METHODS:The medical records of 80 consecutive patients aged less than 17 years of age, who underwent surgery for basic exotropia by a single surgeon between years 2000 to 2009 and completed a minimum of 5y follow-u...

journal_title：International journal of ophthalmology

authors： Chew FL,Gesite-de Leon BU,Quah BL

更新日期：2016-07-18 00:00:00

abstract：AIM:To report the surgical technique and efficacy of the tiled transplantation internal limiting membrane (ILM) pedicle flap technique after vitrectomy for 33 patients with large macular hole (MH). METHODS:This study was a prospective noncontrolled interventional study. All patients were treated by vitrectomy, the til...

journal_title：International journal of ophthalmology

authors： Wang LP,Sun WT,Lei CL,Deng J

更新日期：2019-02-18 00:00:00

abstract：AIM:Tono-pen measurement of intraocular pressure (IOP) under topical anaesthesia in full term normal newborns. METHODS:The IOP measurements were taken using Tono-pen XL tonometer under topical anaesthesia in 150 newborns (300 eyes) within 24h after birth, over a period of three months, in a university hospital. Gender...

journal_title：International journal of ophthalmology

authors： Reddy SC,Alias R

更新日期：2014-02-18 00:00:00

abstract：AIM:To evaluate ocular penetration of topically applied 1% tigecycline. METHODS:Forty-two New Zealand White rabbits were divided into 3 groups. A 50 µL drop of 1% tigecycline was administered in group 1. In groups 2 and 3, the drop was administered every 15min for 60min (keratitis protocol). Aqueous humor samples in g...

journal_title：International journal of ophthalmology

authors： Sakarya Y,Sakarya R,Ozcimen M,Goktas S,Ozcimen S,Alpfidan I,Ivacık IS,Erdogan E,Cetinkaya S,Bukus A

更新日期：2017-05-18 00:00:00

abstract：AIM:To evaluate the role of dietary supplementation of omega-3 fatty acids in dry eye syndrome. METHODS:A prospective, interventional, placebo controlled, double blind randomized trial was done at two referral eye centers. Two hundred and sixty-four eyes of patients with dry eye were randomized to receive one capsule ...

journal_title：International journal of ophthalmology

authors： Bhargava R,Kumar P,Kumar M,Mehra N,Mishra A

更新日期：2013-12-18 00:00:00

abstract：AIM:To estimate the potential systemic events during and after retinopathy of prematurity (ROP) screening. METHODS:A prospective and descriptive designed study was conducted to detect the physiologic and pathological changes 24h before, during, and 72h after ROP screening. Control blood pressure (BP), saturation, puls...

journal_title：International journal of ophthalmology

authors： Jiang JB,Zhang ZW,Zhang JW,Wang YL,Nie C,Luo XQ

更新日期：2016-08-18 00:00:00

abstract：AIM:To evaluate the clinical and optical outcomes after clear corneal incision cataract surgery (CICS) with three different incision sizes (1.8, 2.0 and 3.0 mm). METHODS:Eyes of 150 patients with age-related cataract scheduled for coaxial cataract surgery were randomized to three groups: 1.8, 2.0, or 3.0 mm CICS. Intr...

journal_title：International journal of ophthalmology

authors： Yu YB,Zhu YN,Wang W,Zhang YD,Yu YH,Yao K

更新日期：2016-03-18 00:00:00