Proteomic analysis of energy metabolism and signal transduction in irradiated melanoma cells.

abstract：AIM:To evaluate ocular penetration of topically applied 1% tigecycline. METHODS:Forty-two New Zealand White rabbits were divided into 3 groups. A 50 µL drop of 1% tigecycline was administered in group 1. In groups 2 and 3, the drop was administered every 15min for 60min (keratitis protocol). Aqueous humor samples in g...

journal_title：International journal of ophthalmology

authors： Sakarya Y,Sakarya R,Ozcimen M,Goktas S,Ozcimen S,Alpfidan I,Ivacık IS,Erdogan E,Cetinkaya S,Bukus A

更新日期：2017-05-18 00:00:00

abstract：AIM:To review imaging characteristics and surgical outcomes of orbital neurilemmoma. METHODS:Retrospective review of 21 patients with orbital neurilemmoma managed at the Zhongshan Ophthalmic Center of Sun Yat-sen University from June 2005 to December 2016. All patients underwent surgical excision following preoperativ...

journal_title：International journal of ophthalmology

authors： Chen MH,Yan JH

更新日期：2019-07-18 00:00:00

abstract：AIM:To identify risk factors associated with post-cataract surgery endophthalmitis (PCE) in type 2 diabetic patients. METHODS:A hospital-based retrospective case-control study was conducted on 194 type 2 diabetic patients undergoing cataract surgery in Rajavithi Hospital from January 2007 to December 2015. Fifteen pat...

journal_title：International journal of ophthalmology

authors： Silpa-Archa S,Papirachnart A,Singhanetr P,Preble JM

更新日期：2019-03-18 00:00:00

abstract：AIM:To conduct a systematic review and quantitative Meta-analysis of the efficacy and safety of combined surgery for the eyes with coexisting cataract and open angle glaucoma. METHODS:We performed a systematic search of the related literature in the Cochrane Library, PubMed, EMBASE, Web of Science databases, CNKI, CBM...

journal_title：International journal of ophthalmology

authors： Jiang N,Zhao GQ,Lin J,Hu LT,Che CY,Wang Q,Xu Q,Li C,Zhang J

更新日期：2018-02-18 00:00:00

abstract：AIM:To investigate the efficacy of non-buckled vitrectomy with classical endotamponade agents in the treatment of primary retinal detachment (RD) complicated by inferior breaks and proliferative vitreoretinophathy (PVR). METHODS:A retrospective, consecutive and case series study of 40 patients with inferior break RD a...

journal_title：International journal of ophthalmology

authors： Sheng Y,Sun W,Mo B,Yu YJ,Gu YS,Liu W

更新日期：2012-01-01 00:00:00

abstract：AIM:To compare three initial monthly intravitreal ranibizumab (IVR) injections followed by pro re nata (PRN) dosing with one initial monthly IVR injections followed by PRN dosing for macular edema (ME) secondary to branch retinal vein occlusion (BRVO). METHODS:Forty-two eyes of 42 patients who had IVR injections for B...

journal_title：International journal of ophthalmology

authors： Bayat AH,Çakır A,Özturan ŞG,Bölükbaşı S,Erden B,Elçioğlu MN

更新日期：2018-09-18 00:00:00

abstract：AIM:To compare the changes in corneal biomechanics measured by ocular response analyzer (ORA) after 2.2-mm microincision cataract surgery and 3.0-mm standard coaxial phacoemulsification. METHODS:The prospective nonrandomized study comprised eyes with cataract that had 2.2-mm coaxial microincision or 3.0-mm standard in...

journal_title：International journal of ophthalmology

authors： Zhang Z,Yu H,Dong H,Wang L,Jia YD,Zhang SH

更新日期：2016-02-18 00:00:00

abstract：AIM:To investigate the effect of hypoxia on the proliferation of mouse corneal epithelial cells in vitro. METHODS:Mouse corneal epithelial cells(MCEs) were cultured in normoxia (210mL/L O(2) and 50mL/L CO(2)) and hypoxia (20mL/L O(2) and 50mL/L CO(2)), respectively. Colony forming efficiency (CFE) and cell proliferati...

journal_title：International journal of ophthalmology

authors： Ma XL,Liu HQ

更新日期：2011-01-01 00:00:00

abstract：AIM:To assess choroidal thickness in patients with severe obstructive sleep apnea syndrome (OSAS) and compare them with healthy controls, using spectral domain optical coherence tomography (OCT). METHODS:In this observational, cross-sectional study, choroidal thicknesses of 23 newly severe OSAS patients and 23 body ma...

journal_title：International journal of ophthalmology

authors： Karalezli A,Eroglu FC,Kivanc T,Dogan R

更新日期：2014-12-18 00:00:00

abstract：AIM:To evaluate the quantitatively changes in lipid layer thickness (LLT) when 3% diquafosol eye drop is used for dry eye patients using the tear film interferometer. METHODS:A total 124 participants (32 males, 92 females; mean age, 28.9y) diagnosed with dry eye disease (DED) received topical instillation of 4 ophthal...

journal_title：International journal of ophthalmology

authors： Kang DH,Lee YW,Hwang KY,Koh KM,Kwon YA,Kim BY,Song SW,Kim KY

更新日期：2019-10-18 00:00:00

abstract：:[This retracts the article DOI: 10.3980/j.issn.2222-3959.2015.01.27.]. ...

journal_title：International journal of ophthalmology

authors：

更新日期：2017-07-18 00:00:00

abstract：AIM:To prove anthrax lethal toxin (LeTx) blocks the mitogen activated protein kinases (MAPKs) activation by degrading the MAPK/ERK kinases (MEKs) to suppress vascular endothelial growth factor (VEGF) secretion. METHODS:Human adult retinal pigmented epithelium (ARPE) cells were cultured and treated with normal glucose,...

journal_title：International journal of ophthalmology

authors： Zhang WW,Wang X,Xie P,Yuan ST,Liu QH

更新日期：2015-06-18 00:00:00

abstract：AIM:To observe changes in the content of matrix metalloproteinases (MMPs) in the corneal stroma after corneal cross-linking (CXL) in rabbits, and further explore the corneal pathophysiological process after CXL. METHODS:Forty-two rabbits (42 eyes) were randomly divided into seven groups. One group served as the contro...

journal_title：International journal of ophthalmology

authors： Jia HZ,Pang X,Peng XJ

更新日期：2021-01-18 00:00:00

abstract：AIM:To investigate the cross-talk between oxidative stress and the epidermal growth factor receptor (EGFR)/AKT signaling pathway in retinal pigment epithelial (RPE) cells. METHODS:Human RPE cell lines (ARPE-19 cell) were treated with different doses of epidermal growth factor (EGF) and hydrogen peroxide (H2O2). Cell v...

journal_title：International journal of ophthalmology

authors： Chen XD,Su MY,Chen TT,Hong HY,Han AD,Li WS

更新日期：2017-04-18 00:00:00

abstract：:Non-simulator-based examination methods of the fundal examination have shown to be cost-effective. We reviewed different non-simulator-based direct fundoscopy examination methods used in undergraduate curricula and their outcomes. PubMed (MEDLINE) and Cochrane Database of Systematic Reviews were searched using standar...

journal_title：International journal of ophthalmology

authors： Samaranayake UMJE,Mathangasinghe Y,Samaranayake UMNP,Wijayatunga M

更新日期：2020-04-18 00:00:00

abstract：AIM:To assess strabismus control and motor ocular alignment for basic exotropia surgery at 5y follow-up. METHODS:The medical records of 80 consecutive patients aged less than 17 years of age, who underwent surgery for basic exotropia by a single surgeon between years 2000 to 2009 and completed a minimum of 5y follow-u...

journal_title：International journal of ophthalmology

authors： Chew FL,Gesite-de Leon BU,Quah BL

更新日期：2016-07-18 00:00:00

abstract：AIM:To report the epidemiology and incidence of vitreous hemorrhage and to evaluate risk factors for patients with vitreous hemorrhage (VH) in Taiwan. METHODS:A retrospective population-based study. Analyzing a sample of one million subjects from all enrollees of the Taiwan Health Insurance programme. All data were ob...

journal_title：International journal of ophthalmology

authors： Wang CY,Cheang WM,Hwang DK,Lin CH

更新日期：2017-03-18 00:00:00

abstract：AIM:To analyze and identify the proteomic differences between liquefied after-cataracts and normal lenses by means of liquefied chromatography-tandem mass spectrometry (LC-MS/MS). METHODS:Three normal lenses and three liquefied after-cataracts were exposed to depolymerizing reagents to extract the total proteins. Prot...

journal_title：International journal of ophthalmology

authors： Ge JJ,Huang YS

更新日期：2017-09-18 00:00:00

abstract：AIM:To evaluate the rotational stability and visual outcomes of a single-piece hydrophilic acrylic toric intraocular lenses (IOL) over a 1.5-year follow-up period. Data from the 6-month follow-up study have been previously reported. METHODS:Forty eyes of 26 cataract patients (mean age: 72.8±7.9y) with pre-existing cor...

journal_title：International journal of ophthalmology

authors： Gyöngyössy B,Jirak P,Schönherr U

更新日期：2017-04-18 00:00:00

abstract：AIM:To determine the effects of peripheral corneal thickness (PCT) on dynamic contour tonometry(DCT) and Goldmann applanation tonometry (GAT). METHODS:A cross-sectional study. We created a software which calculates the corneal contour (CC) as a function of the radius from the corneal apex to each pixel of the contour....

journal_title：International journal of ophthalmology

authors： Saenz-Frances F,Sanz-Pozo C,Borrego-Sanz L,Jañez L,Morales-Fernandez L,Martinez-de-la-Casa JM,Garcia-Sanchez J,Garcia-Feijoo J,Santos-Bueso E

更新日期：2017-10-18 00:00:00

abstract：AIM:To estimate the adult reference values for measured deviations by a computerized diplopia test and testify the validity. METHODS:Totally 391 participants were recruited and taken the computerized diplopia test. The plots and amplitude of deviations were recorded. The differences in different gender, age and visual...

journal_title：International journal of ophthalmology

authors： Zhou LY,Liu TJ,Li XM

更新日期：2016-11-18 00:00:00

abstract：AIM:To explore the role of IgG4 serology in identifying common orbital lymphoproliferative disorders. METHODS:Eighty-one patients with orbital lymphoproliferative diseases were treated in the Department of Ocular Oncology, Beijing Tongren Hospital, Capital Medical University between September 2010 and December 2012. S...

journal_title：International journal of ophthalmology

authors： Li J,Ma JM,Ge X

更新日期：2016-02-18 00:00:00

abstract：AIM:To investigate the effects of transforming growth factor β2 (TGF-β2) and connective tissue growth factor (CTGF) on transdifferentiation of human lens epithelial cells (HLECs) cultured in vitro and synthesis of extracellular matrix (ECM). METHODS:HLECs were treated with TGF-β2 (0, 0.5, 1.0, 5, 10µg/L) and CTGF (0, ...

journal_title：International journal of ophthalmology

authors： Pei C,Ma B,Kang QY,Qin L,Cui LJ

更新日期：2013-12-18 00:00:00

abstract：AIM:To investigate clinical characteristics of asymptomatic Terson syndrome and its clinical impact in patients with aneurysmal subarachnoid hemorrhage (SAH). METHODS:This retrospective, interventional study included 31 patients with aneurysmal SAH, and the medical records were reviewed. In addition to baseline charac...

journal_title：International journal of ophthalmology

authors： Kang HM,Cho JM,Kim SY,Choi JH

更新日期：2020-02-18 00:00:00

abstract：AIM:To explore the correlation between the retinal nerve fiber layer (RNFL) thickness by using optical coherence tomography (OCT) and by histological measurements in normal adult rats and optic nerve transected rats. METHODS:The RNFL thickness of 36 rats was scanned in a circle 3.46mm far from the optic disc by OCT. T...

journal_title：International journal of ophthalmology

authors： Huang JF,Yu HM,Shang L,Ma RF,Cynthia NA,Cao YQ,Luo J,Zeng LP,Chen D,Xiong K

更新日期：2013-08-18 00:00:00

abstract：:Our aim was to report quality of life (QOL) outcomes following Xen45 Gel Stent implantation surgery in patients suffering with primary open angle glaucoma (POAG). A retrospective analysis was performed on all patients who had Xen45 implantation surgery during a 2-year period (Jun, 2016-Apr, 2018). Of 52 consecutive pa...

journal_title：International journal of ophthalmology

authors： Hassan F,Thomson LTM,Toor G,Alfahad Q

更新日期：2019-09-18 00:00:00

abstract：AIM:To evaluate the effect of age on visual and refractive results after laser in situ keratomileusis (LASIK) obtained with a mechanical microkeratome or a femtosecond laser. METHODS:Retrospective, nonrandomized, cohort study. A total of 3826 eyes were included in the study (1725 eyes treated with mechanical LASIK and...

journal_title：International journal of ophthalmology

authors： Garcia-Gonzalez M,Gros-Otero J,Rodriguez-Perez I,Rodero A,Teus MA

更新日期：2019-03-18 00:00:00

abstract：:This study is to investigate the characteristic features of Acanthamoeba keratitis (AK) that differentiating it from herpetic epithelial keratitis (HEK) using anterior segment optical coherence tomography (AS-OCT). Medical records of three eyes of each AK and herpetic keratitis who had AS-OCT examination were reviewed...

journal_title：International journal of ophthalmology

authors： Park YM,Lee JS,Yoo JM,Park JM,Seo SW,Chung IY,Kim SJ

更新日期：2018-08-18 00:00:00

abstract：AIM:To analyze the influences of different genotypes (G11778A, T14484C and G3460A) of Leber hereditary optic neuropathy (LHON) on visual prognosis. METHODS:After a systematic literature search, all relevant studies evaluating the association between the three primary mutations of LHON and visual prognosis were include...

journal_title：International journal of ophthalmology

authors： Guo DY,Wang XW,Hong N,Gu YS

更新日期：2016-10-18 00:00:00

abstract：AIM:To examine the cytotoxic effect of pilocarpine, an anti-glaucoma drug, on human corneal stromal (HCS) cells and its underlying cytotoxic mechanisms using an in vitro model of non-transfected HCS cells. METHODS:After HCS cells were treated with pilocarpine at a concentration from 0.15625 g/L to 20.0 g/L, their morp...

journal_title：International journal of ophthalmology

authors： Yuan XL,Wen Q,Zhang MY,Fan TJ

更新日期：2016-04-18 00:00:00