Abstract:
:Our aim was to report quality of life (QOL) outcomes following Xen45 Gel Stent implantation surgery in patients suffering with primary open angle glaucoma (POAG). A retrospective analysis was performed on all patients who had Xen45 implantation surgery during a 2-year period (Jun, 2016-Apr, 2018). Of 52 consecutive patients were included with a total of 58 eyes being operated on. QOL was compared both pre-operatively and 6 weeks post-operatively using the GQL-15 questionnaire. There was an overall improvement in GQL-15 summary scores for our patient group. All item scores showed either no change or some degree of improvement. The Xen45 Gel Stent Implant is a promising new intervention which has shown improved QOL scores in our patient group. Further, higher power studies are now needed to compare the Xen45 to trabeculectomy (TE), which is currently the gold standard.
journal_name
Int J Ophthalmoljournal_title
International journal of ophthalmologyauthors
Hassan F,Thomson LTM,Toor G,Alfahad Qdoi
10.18240/ijo.2019.09.21subject
Has Abstractpub_date
2019-09-18 00:00:00pages
1503-1506issue
9eissn
2222-3959issn
2227-4898pii
ijo-12-09-1503journal_volume
12pub_type
杂志文章abstract::The multiple regression formulas and correlation of ocular components with refractive errors are presented by Gaussian optics. The refractive error changing rate for the cornea and lens power, the axial length, anterior chamber depth (ACD) and vitreous chamber depth (VCD) are calculated, including nonlinear terms for ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.05.26
更新日期:2019-05-18 00:00:00
abstract:AIM:To investigate the protective effect and its mechanism of lycium barbarum polysaccharides (LBP) against oxidative stress-induced apoptosis in human retinal pigment epithelial cells. METHODS:ARPE-19 cells, a human retinal pigment epithelial cell lines, were exposed to different concentrations of H2O2 for 24h, then ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.01.02
更新日期:2015-02-18 00:00:00
abstract:AIM:To evaluate the role of dietary supplementation of omega-3 fatty acids in dry eye syndrome. METHODS:A prospective, interventional, placebo controlled, double blind randomized trial was done at two referral eye centers. Two hundred and sixty-four eyes of patients with dry eye were randomized to receive one capsule ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2013.06.13
更新日期:2013-12-18 00:00:00
abstract:AIM:To analyze proteomic and signal transduction alterations in irradiated melanoma cells. METHODS:We combined stable isotope labeling with amino acids in cell culture (SILAC) with highly sensitive shotgun tandem mass spectrometry (MS) to create an efficient approach for protein quantification. Protein-protein interac...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2013.03.06
更新日期:2013-06-18 00:00:00
abstract:AIM:To investigate the association of Manganese superoxide dismutase (MnSOD) Val16Ala polymorphism with diabetic retinopathy (DR). METHODS:PubMed, Embase, China National Knowledge Infrastructure, and Wanfang databases were searched. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to eva...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.04.22
更新日期:2017-04-18 00:00:00
abstract:AIM:To investigate the published papers of ophthalmology in past ten years and explore the development of ophthalmology. METHORDS:The data of this study retrieved from Science Citation Index Expanded and downloaded online in November 2017, including all the papers with publication year from 2007-2016 were analyzed. Th...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.12.17
更新日期:2017-12-18 00:00:00
abstract:AIM:To review imaging characteristics and surgical outcomes of orbital neurilemmoma. METHODS:Retrospective review of 21 patients with orbital neurilemmoma managed at the Zhongshan Ophthalmic Center of Sun Yat-sen University from June 2005 to December 2016. All patients underwent surgical excision following preoperativ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.07.09
更新日期:2019-07-18 00:00:00
abstract:AIM:To reveal the mechanisms of heat-shock transcription factor 4 (HSF4) mutation-induced cataract. METHODS:GSE22362, including 3 HSF4-null lens and 3 wild-type lens, was obtained from Gene Expression Omnibus database. After data preprocessing, the differentially expressed genes (DEGs) were identified using the limma ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.06.03
更新日期:2018-06-18 00:00:00
abstract:AIM:To study plasma levels of vascular endothelial growth factor (VEGF), endothelin-1(ET-1) and nitric oxide (NO) in patients with proliferative diabetic retinopathy (PDR) before and after pan-retinal photocoagulation (PRP). METHODS:Forty patients (23 females and 17 males, mean age 48.5±12.2 years) with PDR without pr...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2010.01.05
更新日期:2010-01-01 00:00:00
abstract:AIM:To report the surgical technique and efficacy of the tiled transplantation internal limiting membrane (ILM) pedicle flap technique after vitrectomy for 33 patients with large macular hole (MH). METHODS:This study was a prospective noncontrolled interventional study. All patients were treated by vitrectomy, the til...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.02.10
更新日期:2019-02-18 00:00:00
abstract:AIM:To study the histopathological changes in the retina and flash electroretinogram (F-ERG) features of ozone-treated streptozotocin (STZ)-induced diabetic rats. METHODS:Seventy male Sprague Dawley rats were grouped as follows: blank group (GB, n=10), model control group (GM, n=18), ozone group (GO3, n=19), and oxyge...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.06.04
更新日期:2016-06-18 00:00:00
abstract:AIM:To compare three initial monthly intravitreal ranibizumab (IVR) injections followed by pro re nata (PRN) dosing with one initial monthly IVR injections followed by PRN dosing for macular edema (ME) secondary to branch retinal vein occlusion (BRVO). METHODS:Forty-two eyes of 42 patients who had IVR injections for B...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.09.17
更新日期:2018-09-18 00:00:00
abstract:AIM:To analyze the lab diagnosis and etiology of infectious endophthalmitis. METHODS:The medical and microbial records of 36 patients diagnosed with infectious endophthalmitis and 8 patients diagnosed with intraocular lens (IOL)-related inflammation between Nov. 1999 and Dec. 2009 were retrospectively reviewed for lab...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2011.01.23
更新日期:2011-01-01 00:00:00
abstract:AIM:To evaluate the diagnostic value of B-scan ultrasound and explore the cytological characteristics of patients with vitreoretinal lymphoma (VRL) and primary central nervous system lymphoma (PCNSL). METHODS:The clinical data and pathologic specimens from patients with VRL diagnosed at the North Huashan Hospital from...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.06.20
更新日期:2019-06-18 00:00:00
abstract:AIM:To report various ocular injuries caused by durian fruit. METHODS:Three cases of ocular injuries were described in young patients, due to accidental fall of durian fruit on the forehead and face, while they were taking rest/sleeping /playing under the durian tree. RESULTS:The ocular injuries observed were lacerat...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2012.04.25
更新日期:2012-01-01 00:00:00
abstract:AIM:To perform a Meta-analysis on the precision and safety of femtosecond laser (FSL) capsulotomy compared with manual continuous curvilinear capsulotomy (CCC). METHODS:We searched PubMed, EMBASE, Web of Science, the Cochrane Library databases, and Clinical Trials.gov that maintained our inclusion criteria. Reference ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.03.23
更新日期:2016-03-18 00:00:00
abstract:AIM:To determine the incidence of cystoid macular edema (CME) after Descemet's stripping automated endothelial keratoplasty (DSAEK). METHODS:This study included all consecutive patients operated in a Spanish tertiary reference hospital over a period of four years. A total of 55 eyes from 47 patients matched the select...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.07.10
更新日期:2017-07-18 00:00:00
abstract:AIM:To explore the role of IgG4 serology in identifying common orbital lymphoproliferative disorders. METHODS:Eighty-one patients with orbital lymphoproliferative diseases were treated in the Department of Ocular Oncology, Beijing Tongren Hospital, Capital Medical University between September 2010 and December 2012. S...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.02.18
更新日期:2016-02-18 00:00:00
abstract:AIM:To compare the optic disc blood flow of non-arteritic ischemic optic neuropathy (NAION) eyes with normal eyes. METHODS:The optic disc blood flow densities of diagnosed non-acute phase NAION eyes (21 eyes, 14 individuals) and normal eyes (19 eyes, 12 individuals) were detected via Optovue optical coherence tomograp...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.09.12
更新日期:2017-09-18 00:00:00
abstract::The incidence of diabetes mellitus (DM) and its complications have increased considerably worldwide. Diabetic keratopathy is the major complication of the cornea characterized by delayed corneal wound healing, decreasing corneal epithelial sensitivity, and recurrent corneal ulcers. There is accumulating evidence that ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.18240/ijo.2019.12.17
更新日期:2019-12-18 00:00:00
abstract:AIM:To investigate the effect of protein kinase C (PKC) on transforming growth factor-β(2) (TGFβ(2)) and dopamine in retinal Müller cells of guinea pig myopic eye. METHODS:Myopia was induced by translucent goggles in guinea pig, whose retinal Müller cells were cultured using the enzyme-digesting method. Retinal Müller...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2011.04.06
更新日期:2011-01-01 00:00:00
abstract:AIM:To investigate the effect of Bak Foong Pills (BFP) on the expression of β-amyloid (Aβ) in rats retina with optic nerve transection, and its roles and possible mechanisms in protecting optic nerve damage. METHODS:Seventy-two healthy, Sprague-Dawley, adult rats were randomly assigned to three groups: negative contro...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2011.01.13
更新日期:2011-01-01 00:00:00
abstract:AIM:To explore the effect of saturated hydrogen saline on blue light-induced retinal damage in rats. METHODS:The retinal damage of rats was induced by blue light exposure for 6 hours and examined 8 hours, 16 hours and 24 hours after the exposure. One hundred female Sprague-Dawley rats were randomly divided into four g...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2012.02.07
更新日期:2012-01-01 00:00:00
abstract:AIM:To investigate the variation of IGSF3 gene in three families with congenital absence of lacrimal puncta and canaliculi, and to lay a foundation for further research on the pathogenic gene of congenital lacrimal duct agenesis. METHODS:The members of the three families were recruited. The ophthalmologic examinations...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2020.09.02
更新日期:2020-09-18 00:00:00
abstract:AIM:To investigate the incidence and the predisposing factors of anterior chamber (AC) gas bubbles during femtosecond laser (FS) flap creation for laser in situ keratomileusis (LASIK). METHODS:All patients who underwent FS-LASIK surgery at CMU LASIK Center between January 2013 and May 2016 were retrospective reviewed....
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2020.08.22
更新日期:2020-08-18 00:00:00
abstract:AIM:To investigate extent and nature of visual pathways involvement in children with clinically isolated syndrome (CIS). METHODS:Forty-seven patients (age 11-17y) with CIS, which later proved to be multiple sclerosis (MS) onset, and 30 controls underwent visual evoked potentials (VEP) investigation within 12d from the...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.02.30
更新日期:2015-04-18 00:00:00
abstract:AIM:To observe changes in the content of matrix metalloproteinases (MMPs) in the corneal stroma after corneal cross-linking (CXL) in rabbits, and further explore the corneal pathophysiological process after CXL. METHODS:Forty-two rabbits (42 eyes) were randomly divided into seven groups. One group served as the contro...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2021.01.04
更新日期:2021-01-18 00:00:00
abstract:AIM:To compare posterior capsule opacification (PCO) degree and visual functions after phacoemulsification in eyes implanted with 360-degree square edge hydrophilic acrylic intraocular lens (IOL) (570C C-flex, Rayner) and sharp edge hydrophobic acrylic IOL (Sensar AR40e, AMO) in diabetic patients. METHODS:Sixty diabet...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.04.15
更新日期:2015-08-18 00:00:00
abstract:AIM:To investigate the impact of non-Descemet stripping endothelial keratoplasty (non-DSEK) on graft rejection rate, and its overall procedural effectiveness in patients. METHODS:Non-DSEK was performed on 65 eyes of 64 patients, and the procedural outcomes, including rejection episodes, failure and dislocation of the ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.02.07
更新日期:2017-02-18 00:00:00
abstract::Most of the ocular tumors have poor prognosis, and they remain a difficult problem in the area of ophthalmology. With the rapid development of molecular biology and immunologic techniques and the deep research on ocular tumor related genes, it becomes possible to diagnose and treat malignant tumors from the molecular ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2011.05.18
更新日期:2011-01-01 00:00:00