Anthrax lethal toxin suppresses high glucose induced VEGF over secretion through a post-translational mechanism.

abstract：AIM:To describe and compare the corneal endothelial cell density and morphology in young, low and moderate myopic Chinese adults in Malaysian Chinese population. METHODS:Non-contact specular microscopy (Topcon SP3000P, Tokyo, Japan) was performed in low (n=78; 21.22±1.51 years) and moderate (n=78; 21.82±1.40 years) my...

journal_title：International journal of ophthalmology

authors： Delshad S,Chun JM

更新日期：2013-08-18 00:00:00

abstract：AIM:To report various ocular injuries caused by durian fruit. METHODS:Three cases of ocular injuries were described in young patients, due to accidental fall of durian fruit on the forehead and face, while they were taking rest/sleeping /playing under the durian tree. RESULTS:The ocular injuries observed were lacerat...

journal_title：International journal of ophthalmology

authors： Reddy SC

更新日期：2012-01-01 00:00:00

abstract：AIM:To estimate the adult reference values for measured deviations by a computerized diplopia test and testify the validity. METHODS:Totally 391 participants were recruited and taken the computerized diplopia test. The plots and amplitude of deviations were recorded. The differences in different gender, age and visual...

journal_title：International journal of ophthalmology

authors： Zhou LY,Liu TJ,Li XM

更新日期：2016-11-18 00:00:00

abstract：AIM:To investigate the fundus manifestations and human immunodeficiency virus (HIV) viral loads of acquired immune deficiency syndrome (AIDS) patients before and after highly active antiretroviral therapy (HAART). METHODS:This retrospective study included 21 AIDS patients (42 eyes) who presented to the Department of O...

journal_title：International journal of ophthalmology

authors： Di Y,Zhao XY,Ye JJ,Li B,Ma N

更新日期：2019-09-18 00:00:00

abstract：AIM:To evaluate ocular penetration of topically applied 1% tigecycline. METHODS:Forty-two New Zealand White rabbits were divided into 3 groups. A 50 µL drop of 1% tigecycline was administered in group 1. In groups 2 and 3, the drop was administered every 15min for 60min (keratitis protocol). Aqueous humor samples in g...

journal_title：International journal of ophthalmology

authors： Sakarya Y,Sakarya R,Ozcimen M,Goktas S,Ozcimen S,Alpfidan I,Ivacık IS,Erdogan E,Cetinkaya S,Bukus A

更新日期：2017-05-18 00:00:00

abstract：AIM:To elucidate the relationship between systemic risk factors and different patterns of diabetic macular edema (DME) determined with optical coherence tomography (OCT). METHODS:In this cross-sectional study, DME was classified by OCT as diffuse retinal thickness (DRT), cystoid macular edema (CME) and serous retinal ...

journal_title：International journal of ophthalmology

authors： Acan D,Karahan E,Kocak N,Kaynak S

更新日期：2018-07-18 00:00:00

abstract：AIM:To evaluate the efficacy and safety of orbital decomposition (OD) surgery in combination with horse chestnut seed extract (HCSE), as compared to OD alone, in patients with thyroid-associated ophthalmopathy (TAO). METHODS:Sixty-two orbits from 62 TAO patients were randomly assigned to OD or OD+HCSE at 1:1 ratio (31...

journal_title：International journal of ophthalmology

authors： Wu YJ,Wei X,Xiao MY,Xiong W

更新日期：2016-06-18 00:00:00

abstract：AIM:To evaluate the efficacy of modified corneal ulcer debridement in superficial fungal keratitis unresponsive to medications. METHODS:A total of 209 patients (209 eyes) with fungal keratitis, involving no more than 50% of the stromal depth and not responding to antifungal agents for 2wk, were recruited in this retro...

journal_title：International journal of ophthalmology

authors： Wang JY,Wang DQ,Qi XL,Cheng J,Xie LX

更新日期：2018-02-18 00:00:00

abstract：:Retinal diseases, including age-related macular degeneration (AMD) and diabetic retinopathy (DR) are the leading causes of blindness in adults over the age of 50 years in the US. While most of those conditions do not have a cure, currently available treatment options attempt to prevent further vision loss. For many op...

journal_title：International journal of ophthalmology

authors： Jiang S,Franco YL,Zhou Y,Chen J

更新日期：2018-06-18 00:00:00

abstract：AIM:To determine the effects of peripheral corneal thickness (PCT) on dynamic contour tonometry(DCT) and Goldmann applanation tonometry (GAT). METHODS:A cross-sectional study. We created a software which calculates the corneal contour (CC) as a function of the radius from the corneal apex to each pixel of the contour....

journal_title：International journal of ophthalmology

authors： Saenz-Frances F,Sanz-Pozo C,Borrego-Sanz L,Jañez L,Morales-Fernandez L,Martinez-de-la-Casa JM,Garcia-Sanchez J,Garcia-Feijoo J,Santos-Bueso E

更新日期：2017-10-18 00:00:00

abstract：AIM:To explore the roles of phospholipids and sphingolipids in the inflammatory process of uveitis. METHODS:Aqueous humor (AH) and the retina were obtained from endotoxin-induced uveitis (EIU) rats during the acute inflammation stage (24h after endotoxin injection). Lipids were extracted using a modified Bligh and Dye...

journal_title：International journal of ophthalmology

authors： Wang HY,Wang Y,Zhang Y,Wang J,Xiong SY,Sun Q

更新日期：2018-05-18 00:00:00

abstract：AIM:To perform a Meta-analysis on the precision and safety of femtosecond laser (FSL) capsulotomy compared with manual continuous curvilinear capsulotomy (CCC). METHODS:We searched PubMed, EMBASE, Web of Science, the Cochrane Library databases, and Clinical Trials.gov that maintained our inclusion criteria. Reference ...

journal_title：International journal of ophthalmology

authors： Qian DW,Guo HK,Jin SL,Zhang HY,Li YC

更新日期：2016-03-18 00:00:00

abstract：AIM:To investigate the effect of broccoli sprouts juice in preventing lens protein aggregation in diabetic rat model. METHODS:Totally 25 male Wistar rats were divided into negative control group, diabetic group without juice treatment as positive control and diabetic group given broccoli sprouts juice 0.25, 0.5 and 1 ...

journal_title：International journal of ophthalmology

authors： Puspitasari A,Handayani N

更新日期：2019-09-18 00:00:00

abstract：AIM:To investigate the hematological parameters, biochemical and electrophysiological role of acrylamide (ACR) in the retina and to assess whether selenium (Se) has protective potential in experimental oral intoxication with ACR. METHODS:Sixty Wistar age matched-albino rats (3mo) weighing 195-230 g comprised of both s...

journal_title：International journal of ophthalmology

authors： Ali MA,Aly EM,Elawady AI

更新日期：2014-08-18 00:00:00

abstract：AIM:To evaluate the effect of exogenous recombinant human bone morphogenic protein-7 (rhBMP-7) on transforming growth factor-β (TGF-β)-induced epithelial mesenchymal cell transition (EMT) and assessed its antifibrotic effect via topical application. METHODS:The cytotoxic effect of rhBMP-7 was evaluated and the EMT of ...

journal_title：International journal of ophthalmology

authors： Chung JK,Park SA,Hwang HS,Kim KS,Cho YJ,You YS,Kim YS,Jang JW,Lee SJ

更新日期：2017-03-18 00:00:00

abstract：AIM:To investigate whether the enhanced green fluorescent protein (EGFP) reporter gene could be transferred into human trabecular meshwork (HTM) cells by a HIV-based lentivirus both in vitro and ex vivo. METHODS:The HIV-based lentivirus that contains an EF1-α promoter driving EGFP expression cassette was constructed f...

journal_title：International journal of ophthalmology

authors： Xiang Y,Li B,Wang JM,Li GG,Zhang H,Manyande A,Tian XB

更新日期：2014-12-18 00:00:00

abstract：AIM:To determine the risk factors for acute endophthalmitis after cataract extraction in a tertiary care centre in India. METHODS:We performed a nested case control study within a retrospective cohort. The surgical records of all patients with clinically diagnosed endophthalmitis within one month after cataract surger...

journal_title：International journal of ophthalmology

authors： Khanna RC,Ray VP,Latha M,Cassard SD,Mathai A,Sekhar GC

更新日期：2015-12-18 00:00:00

abstract：AIM:To report the outcomes of patients undergoing anterior segment optical coherence tomography-guided transepithelial phototherapeutic keratectomy (ASOCT T-PTK) for central corneal scarring after pterygium excision. METHODS:The charts of 11 eyes of 10 patients that underwent ASOCT T-PTK following excision of visual a...

journal_title：International journal of ophthalmology

authors： Rush SW,Rush RB

更新日期：2020-03-18 00:00:00

abstract：AIM:To investigate the impact of non-Descemet stripping endothelial keratoplasty (non-DSEK) on graft rejection rate, and its overall procedural effectiveness in patients. METHODS:Non-DSEK was performed on 65 eyes of 64 patients, and the procedural outcomes, including rejection episodes, failure and dislocation of the ...

journal_title：International journal of ophthalmology

authors： Zhang T,Li SW,Chen TH,He JL,Kang YW,Lyu FQ,Ning JH,Liu C

更新日期：2017-02-18 00:00:00

abstract：AIM:To determine whether intravitreal dexamethasone (DEX) implant induces posterior vitreous detachment or not. METHODS:We retrospectively reviewed 810 eyes of 405 patients who underwent intravitreal DEX implantation due to macular edema caused by diabetic and retinal venous occlusion in our clinic. The eyes having no...

journal_title：International journal of ophthalmology

authors： Alpay A

更新日期：2019-08-18 00:00:00

abstract：:The use of personal protective equipment (PPE) for ophthalmologists caring for asymptomatic patients remains controversial. This commentary reviews the latest emerging evidence. This is paramountly important in shaping health policies in countries which is not currently recommended. ...

journal_title：International journal of ophthalmology

authors： Fung AT

更新日期：2020-12-18 00:00:00

abstract：AIM:To record aberrations with a corneal topographic device on the anterior surface of the cornea at different time-points prior to wearing and following discontinued use of rigid gas permeable (RGP) contact lenses. The effect of wearing RGP on the anterior surface of the cornea was discussed to provide guidance for cl...

journal_title：International journal of ophthalmology

authors： Yu Q,Wu JX,Zhang HN,Ye S,Dong SQ,Zhang CH

更新日期：2013-04-18 00:00:00

abstract：AIM:To determine the influence of the dialysis time before kidney transplantation on postoperative ophthalmic complications. METHODS:One hundred and eighty three patients who were given the follow-up after kidney transplantation were selected, including 124 males and 59 females. The dialysis time before kidney transpl...

journal_title：International journal of ophthalmology

authors： Wang YL,Qi F,Xie JL,Qi L,Zhou C,Zhu XR,Ding X,Yang B,Jin P

更新日期：2012-01-01 00:00:00

abstract：AIM:To explore the effects of αA-crystallin in astrocyte gliosis after optic nerve crush (ONC) and the mechanism of α-crystallin in neuroprotection and axon regeneration. METHODS:ONC was established on the Sprague-Dawley rat model and αA-crystallin (10(-4) g/L, 4 µL) was intravitreously injected into the rat model. Fl...

journal_title：International journal of ophthalmology

authors： Shao WY,Liu X,Gu XL,Ying X,Wu N,Xu HW,Wang Y

更新日期：2016-07-18 00:00:00

abstract：AIM:To study the imaging characteristics of lacrimal punctum lesion with optical coherence tomography (OCT), and provide imaging basis for the diagnosis and treatment of lacrimal punctum diseases. METHODS:A total of 25 patients (28 eyes) with epiphora and lacrimal puncta lesions were enrolled. Lacrimal puncta lesions ...

journal_title：International journal of ophthalmology

authors： Tao H,Wang YS,Wang F,Wang HB,Dong WL,Bai F,Wang P,Zhou XB,Wang LH,Liu C

更新日期：2020-06-18 00:00:00

abstract：AIM:To describe a novel technique of creating a landing strip within the trabecular meshwork to guide trabecular micro-bypass stent (iStent) implantation in patients who underwent phacoemulsification. METHODS:Thirty-four eyes from 30 patients who underwent iStent implantation after phacoemulsification from May 2014 to...

journal_title：International journal of ophthalmology

authors： Zheng CX,Moster MR,Gogte P,Dai Y,Manzi RS,Waisbourd M

更新日期：2017-05-18 00:00:00

abstract：AIM:To characterize the proliferative capacity of pterygial epithelium in different regions (head, neck and body) of pterygium and explore the function of transcription factor 4 (TCF4) in pterygium proliferation. METHODS:Thirty pterygium tissues and 10 normal conjunctival tissues were obtained from Zhongshan Ophthalmi...

journal_title：International journal of ophthalmology

authors： Nie C,Zhang XC,Xu SY,Quan YD,Tang ZX,Lu R

更新日期：2018-09-18 00:00:00

abstract：AIM:To observe the curative effect of bandage contact lens in neurogenic keratitis. METHODS:Twenty cases of neurogenic keratitis were studied at the Department of Ophthalmology, the first Affiliated Hospital of China Medical University, between October 2012 and June 2013. These included 13 males and 7 females, aged fr...

journal_title：International journal of ophthalmology

authors： Sun YZ,Guo L,Zhang FS

更新日期：2014-12-18 00:00:00

abstract：AIM:To investigate the incidence and the predisposing factors of anterior chamber (AC) gas bubbles during femtosecond laser (FS) flap creation for laser in situ keratomileusis (LASIK). METHODS:All patients who underwent FS-LASIK surgery at CMU LASIK Center between January 2013 and May 2016 were retrospective reviewed....

journal_title：International journal of ophthalmology

authors： Niparugs M,Supalaset S,Tangmonkongvoragul C,Tananuvat N,Chaidaroon W,Ausayakhun S

更新日期：2020-08-18 00:00:00

abstract：AIM:To construct adenovirus vectors of lumican gene by gateway recombinant cloning technology to further understand the role of lumican gene in myopia. METHODS:Gateway recombinant cloning technology was used to construct adenovirus vectors. The wild-type (wt) and mutant (mut) forms of the lumican gene were synthesized...

journal_title：International journal of ophthalmology

authors： Wang GF,Qi B,Tu LL,Liu L,Yu GC,Zhong JX

更新日期：2016-09-18 00:00:00