Nanotechnology in retinal drug delivery.

abstract：AIM:To analyze the influences of different genotypes (G11778A, T14484C and G3460A) of Leber hereditary optic neuropathy (LHON) on visual prognosis. METHODS:After a systematic literature search, all relevant studies evaluating the association between the three primary mutations of LHON and visual prognosis were include...

journal_title：International journal of ophthalmology

authors： Guo DY,Wang XW,Hong N,Gu YS

更新日期：2016-10-18 00:00:00

abstract：:Non-simulator-based examination methods of the fundal examination have shown to be cost-effective. We reviewed different non-simulator-based direct fundoscopy examination methods used in undergraduate curricula and their outcomes. PubMed (MEDLINE) and Cochrane Database of Systematic Reviews were searched using standar...

journal_title：International journal of ophthalmology

authors： Samaranayake UMJE,Mathangasinghe Y,Samaranayake UMNP,Wijayatunga M

更新日期：2020-04-18 00:00:00

abstract：AIM:To determine the dominant predictive factors of postoperative visual recovery for patients with pituitary adenoma. METHODS:PubMed, Google Scholar, Web of Science and Cochrane Library were searched for relevant human studies, which investigated the prediction of the postoperative visual recovery of patients with pi...

journal_title：International journal of ophthalmology

authors： Sun M,Zhang ZQ,Ma CY,Chen SH,Chen XJ

更新日期：2017-11-18 00:00:00

abstract：AIM:To evaluate ocular penetration of topically applied 1% tigecycline. METHODS:Forty-two New Zealand White rabbits were divided into 3 groups. A 50 µL drop of 1% tigecycline was administered in group 1. In groups 2 and 3, the drop was administered every 15min for 60min (keratitis protocol). Aqueous humor samples in g...

journal_title：International journal of ophthalmology

authors： Sakarya Y,Sakarya R,Ozcimen M,Goktas S,Ozcimen S,Alpfidan I,Ivacık IS,Erdogan E,Cetinkaya S,Bukus A

更新日期：2017-05-18 00:00:00

abstract：AIM:To evaluate the surgical treatment and visual outcomes of eyes with cataract and persistent hyperplastic primary vitreous (PHPV). METHODS:This retrospective study included patients with cataract and PHPV treated with various strategies. Anterior PHPV was treated using phacoemulsification with underwater electric c...

journal_title：International journal of ophthalmology

authors： Li L,Fan DB,Zhao YT,Li Y,Cai FF,Zheng GY

更新日期：2017-03-18 00:00:00

abstract：AIM:To analyze the risk factors, ophthalmological features, treatment modalities and their effect on the visual outcome in patients with endogenous fungal endophthalmitis (EFE). METHODS:Data retrieved from the medical files included age at presentation to the uveitis clinic, gender, ocular symptoms and their duration ...

journal_title：International journal of ophthalmology

authors： Corredores J,Hemo I,Jaouni T,Habot-Wilner Z,Kramer M,Shulman S,Jabaly-Habib H,Al-Talbishi A,Halpert M,Averbukh E,Levy J,Deitch-Harel I,Amer R

更新日期：2021-01-18 00:00:00

abstract：AIM:To construct adenovirus vectors of lumican gene by gateway recombinant cloning technology to further understand the role of lumican gene in myopia. METHODS:Gateway recombinant cloning technology was used to construct adenovirus vectors. The wild-type (wt) and mutant (mut) forms of the lumican gene were synthesized...

journal_title：International journal of ophthalmology

authors： Wang GF,Qi B,Tu LL,Liu L,Yu GC,Zhong JX

更新日期：2016-09-18 00:00:00

abstract：AIM:To evaluate the effect of incision types for Artisan phakic intraocular lens (PIOL) implantation on ocular higher-order aberrations (HOAs). METHODS:A retrospective review was conducted of the patients who had undergone Artisan PIOL implantation for the correction of myopia and followed up for at least 6mo. Patient...

journal_title：International journal of ophthalmology

authors： Park YM,Choi BJ,Lee JS

更新日期：2016-12-18 00:00:00

abstract：AIM:To investigate the relationship between C-reactive protein (CRP) and diabetic retinopathy (DR) in a cohort of Chinese patients with type 2 diabetes mellitus (T2DM). METHODS:Community-based observational cohort study. There were 1131 participants recruited from November 2009 to September 2011 in Desheng community i...

journal_title：International journal of ophthalmology

authors： Yang XF,Deng Y,Gu H,Lim A,Snellingen T,Liu XP,Wang NL,Domalpally A,Danis R,Liu NP

更新日期：2016-01-18 00:00:00

abstract：AIM:To attempt to identify the primary targets of carbamylation in bovine lenses incubated under physiological condition. METHODS:Fresh intact bovine lenses were incubated with [(14)C]-labelled potassium cyanate for seven days. The water-soluble proteins (WSP) of both cortex and nucleus lens were isolated by size-excl...

journal_title：International journal of ophthalmology

authors： Yan H,Zhang J,Harding JJ

更新日期：2010-01-01 00:00:00

abstract：AIM:To investigate the effect of protein kinase C (PKC) on transforming growth factor-β(2) (TGFβ(2)) and dopamine in retinal Müller cells of guinea pig myopic eye. METHODS:Myopia was induced by translucent goggles in guinea pig, whose retinal Müller cells were cultured using the enzyme-digesting method. Retinal Müller...

journal_title：International journal of ophthalmology

authors： Mao JF,Liu SZ,Qin WJ,Xiang Q

更新日期：2011-01-01 00:00:00

abstract：AIM:To estimate the adult reference values for measured deviations by a computerized diplopia test and testify the validity. METHODS:Totally 391 participants were recruited and taken the computerized diplopia test. The plots and amplitude of deviations were recorded. The differences in different gender, age and visual...

journal_title：International journal of ophthalmology

authors： Zhou LY,Liu TJ,Li XM

更新日期：2016-11-18 00:00:00

abstract：AIM:To construct functional human full-thickness corneal replacements. METHODS:Acellular porcine corneal matrix (APCM) was developed from porcine cornea by decellulariztion. The biomechanical properties of anterior-APCM (AAPCM) and posterior-APCM (PAPCM) were checked using uniaxial tensile testing. Human corneal cells...

journal_title：International journal of ophthalmology

authors： Zhang K,Ren XX,Li P,Pang KP,Wang H

更新日期：2019-03-18 00:00:00

abstract：AIM:To detect the association between macular pigment optical density (MPOD), which reflects the antioxidant ability of retina, and diabetic retinopathy (DR) and to investigate the correlated factors of MPOD. METHODS:Totally 435 subjects of urban Chinese were recruited to the study and divided into 3 groups: non-diabe...

journal_title：International journal of ophthalmology

authors： She CY,Gu H,Xu J,Yang XF,Ren XT,Liu NP

更新日期：2016-10-18 00:00:00

abstract：AIM:To quantify the changes in the lens profile with accommodation in different age groups. METHODS:The Pentacam HR system was used to obtain the images of the anterior eye segment from 23 young and 15 presbyopic emmetropic subjects in unaccommodated (with an accommodation stimulus of 0.0D) and accommodated (with an a...

journal_title：International journal of ophthalmology

authors： Ni Y,Liu XL,Wu MX,Lin Y,Sun YY,He C,Liu YZ

更新日期：2011-01-01 00:00:00

abstract：AIM:To study the effect of different flap sizes on visual acuity, refractive outcomes, and aberrations after femtosecond laser for laser in situ keratomileusis (LASIK). METHODS:In each of the forty patients enrolled, 1 eye was randomly assigned to receive treatment with a 8.1mm diameter corneal flap, defined as the sm...

journal_title：International journal of ophthalmology

authors： Zhang YL,Liu L,Cui CX,Hu M,Li ZN,Cao LJ,Jing XH,Mu GY

更新日期：2013-10-18 00:00:00

abstract：AIM:To evaluate the fractal feature of the retinal vasculature of normal eyes on a stereographic projected and montaged ultra-wide field (UWF) fluorescein angiography (FA). METHODS:Prospective, observational, cross-sectional study. Totally 59 eyes of 31 normal subjects were imaged using the Optos 200Tx. Images obtaine...

journal_title：International journal of ophthalmology

authors： Fan WY,Fleming A,Robertson G,Uji A,van Hemert J,Singer M,Sagong M,Ip M,Sadda SR

更新日期：2020-07-18 00:00:00

abstract：AIM:To analyze the systemic factors including stroke history related to the retinal artery occlusion (RAO). METHODS:Patients with an exact diagnosis of RAO in the medical database of the Kailuan Corporation were identified as the case group. Five patients without RAO were added for each case from the Kailuan Study and...

journal_title：International journal of ophthalmology

authors： Xiao YY,Wei WB,Wang YX,Lu AD,Chen SH,Song L,Wu SL

更新日期：2020-03-18 00:00:00

abstract：AIM:To examine the cytotoxic effect of pilocarpine, an anti-glaucoma drug, on human corneal stromal (HCS) cells and its underlying cytotoxic mechanisms using an in vitro model of non-transfected HCS cells. METHODS:After HCS cells were treated with pilocarpine at a concentration from 0.15625 g/L to 20.0 g/L, their morp...

journal_title：International journal of ophthalmology

authors： Yuan XL,Wen Q,Zhang MY,Fan TJ

更新日期：2016-04-18 00:00:00

abstract：:Valsalva retinopathy was described as a particular form of retinopathy, pre-retinal and subinternal limiting membrane haemorrhages in nature that rarely may break through and become subhyloid or intravitreal, secondary to a sudden increase in intrathoracic pressure. We reported a new way that Nd:YAG laser for ILM hyal...

journal_title：International journal of ophthalmology

authors： Hua R,Liu LM,Hu YD,Zhou Y,Chen L

更新日期：2013-04-18 00:00:00

abstract：AIM:To describe the complex, overlapping phenotype of four Chinese patients with inherited retinal dystrophies (IRDs) who harbored two pathogenic genes simultaneously. METHODS:This retrospective study included 4 patients affected with IRDs. Medical and ophthalmic histories were obtained, and clinical examinations were...

journal_title：International journal of ophthalmology

authors： Liu XZ,Tao TC,Qi H,Feng SN,Chen NN,Zhao L,Ma ZZ,Li GL,Yang LP

更新日期：2020-02-18 00:00:00

abstract：AIM:To investigate the levels of serum soluble intercellular adhesion molecules-1(sICAM-1) and neutrophilic expression of CD18 in patients with various stages of diabetic retinopathy and to determine their different expression pattern in the development of diabetic retinopathy(DR). METHODS:Levels of serum sICAM-1 and ...

journal_title：International journal of ophthalmology

authors： Ai H,Song HP

更新日期：2012-01-01 00:00:00

abstract：AIM:To perform a Meta-analysis on the precision and safety of femtosecond laser (FSL) capsulotomy compared with manual continuous curvilinear capsulotomy (CCC). METHODS:We searched PubMed, EMBASE, Web of Science, the Cochrane Library databases, and Clinical Trials.gov that maintained our inclusion criteria. Reference ...

journal_title：International journal of ophthalmology

authors： Qian DW,Guo HK,Jin SL,Zhang HY,Li YC

更新日期：2016-03-18 00:00:00

abstract：AIM:To investigate the incidence and the predisposing factors of anterior chamber (AC) gas bubbles during femtosecond laser (FS) flap creation for laser in situ keratomileusis (LASIK). METHODS:All patients who underwent FS-LASIK surgery at CMU LASIK Center between January 2013 and May 2016 were retrospective reviewed....

journal_title：International journal of ophthalmology

authors： Niparugs M,Supalaset S,Tangmonkongvoragul C,Tananuvat N,Chaidaroon W,Ausayakhun S

更新日期：2020-08-18 00:00:00

abstract：AIM:To compare and evaluate the clinical outcomes of deep anterior lamellar keratoplasty (DALK) and excimer laser assisted anterior lamellar keratoplasty (ELLK) in eyes with keratoconus. METHODS:In this study, 57 eyes of 56 patients operated between 2013 to 2017 were included. Thirty-one eyes underwent big-bubble DALK...

journal_title：International journal of ophthalmology

authors： Ceylanoglu KS,Aydin B,Ozmen MC

更新日期：2019-04-18 00:00:00

abstract：AIM:To investigate a possible trigeminal proprioceptive-oculomotor neural pathway and explore possible synaptic connections between neurons in this pathway. Attempt to bring a new insight to mechanism of Marcus Gunn syndrome (MGS). METHODS:Anterograde and retrograde tract tracing was applied and combined with immunofl...

journal_title：International journal of ophthalmology

authors： Liang HC,Zhang JD,Luo PF,Qiao Y,Su AL,Zhang T,Zhu HN

更新日期：2018-03-18 00:00:00

abstract：AIM:To observe changes in the content of matrix metalloproteinases (MMPs) in the corneal stroma after corneal cross-linking (CXL) in rabbits, and further explore the corneal pathophysiological process after CXL. METHODS:Forty-two rabbits (42 eyes) were randomly divided into seven groups. One group served as the contro...

journal_title：International journal of ophthalmology

authors： Jia HZ,Pang X,Peng XJ

更新日期：2021-01-18 00:00:00

abstract：AIM:To assess the refractive status, anterior chamber depth (ACD) and axial length (AL) of patients with primary angle-closure disease (PACD). METHODS:Retrospective cohort. Data was collected from charts of all PACD patients treated from April 2013 to December 2015. Analysis was done on 137 patient charts with complet...

journal_title：International journal of ophthalmology

authors： Mohamed-Noor J,Abd-Salam D

更新日期：2017-08-18 00:00:00

abstract：AIM:To describe the clinical characteristics and late results of patients with retinopathy of prematurity (ROP) treated with "6h cryotherapy". METHODS:Out of 1252 infants screened for ROP, 52 patients were treated with temporal 6h cryotherapy from 1997 to 2005 were recalled to our clinic. Among these 23 patients were ...

journal_title：International journal of ophthalmology

authors： Cerman E,Ozarslan Ozcan D,Celiker H,Eraslan M,Sahin O,Kazokoglu H

更新日期：2016-04-18 00:00:00

abstract：AIM:To examine which anesthesia general or local is more effective for penetrating keratoplasty (PKP). METHODS:Patients with indications for PKP (n=141) were enrolled in a prospective study and randomly divided into general anesthesia group (group A, 70 eyes) and local anesthesia group (group B, 71 eyes). Patients rec...

journal_title：International journal of ophthalmology

authors： Wang X,Dang GF,Li YM,Li WF,Wu XY

更新日期：2014-04-18 00:00:00