Modulation of TGFβ(2) and dopamine by PKC in retinal Müller cells of guinea pig myopic eye.

abstract：AIM:To explore the effects of αA-crystallin in astrocyte gliosis after optic nerve crush (ONC) and the mechanism of α-crystallin in neuroprotection and axon regeneration. METHODS:ONC was established on the Sprague-Dawley rat model and αA-crystallin (10(-4) g/L, 4 µL) was intravitreously injected into the rat model. Fl...

journal_title：International journal of ophthalmology

authors： Shao WY,Liu X,Gu XL,Ying X,Wu N,Xu HW,Wang Y

更新日期：2016-07-18 00:00:00

abstract：AIM:To analyze the correlation between macular morphology and function in eyes with diabetic macular edema (DME). METHODS:Fifty-five eyes with different visual acuity (VA) of 32 patients who suffered from DME were analyzed using multifocal electroretinography (mfERG) and optical coherence tomography (OCT). The paramet...

journal_title：International journal of ophthalmology

authors： Xia HH,Chen JL,Chen HY,Lin HJ

更新日期：2020-10-18 00:00:00

abstract：AIM:To quantitatively evaluate the effect of the combined use of 577-nm subthreshold micropulse macular laser (SML) and multi-point mode pan retinal laser photocoagulation (PRP) on severe non-proliferative diabetic retinopathy (NPDR) with central-involved diabetic macular edema (CIDME) using optical coherence tomograph...

journal_title：International journal of ophthalmology

authors： Li ZJ,Xiao JH,Zeng P,Zeng R,Gao X,Zhang YC,Lan YQ

更新日期：2020-08-18 00:00:00

abstract：AIM:To evaluate the efficacy and safety of orbital decomposition (OD) surgery in combination with horse chestnut seed extract (HCSE), as compared to OD alone, in patients with thyroid-associated ophthalmopathy (TAO). METHODS:Sixty-two orbits from 62 TAO patients were randomly assigned to OD or OD+HCSE at 1:1 ratio (31...

journal_title：International journal of ophthalmology

authors： Wu YJ,Wei X,Xiao MY,Xiong W

更新日期：2016-06-18 00:00:00

abstract：AIM:To assess the proportion of refractive errors in the Mexican population that visited primary care optometry clinics in fourteen states of Mexico. METHODS:Refractive data from 676 856 patients aged 6 to 90y were collected from optometry clinics in fourteen states of Mexico between 2014 and 2015. The refractive erro...

journal_title：International journal of ophthalmology

authors： Gomez-Salazar F,Campos-Romero A,Gomez-Campaña H,Cruz-Zamudio C,Chaidez-Felix M,Leon-Sicairos N,Velazquez-Roman J,Flores-Villaseñor H,Muro-Amador S,Guadron-Llanos AM,Martinez-Garcia JJ,Murillo-Llanes J,Sanchez-Cuen J,Llausas-Var

更新日期：2017-05-18 00:00:00

abstract：AIM:To investigate the hematological parameters, biochemical and electrophysiological role of acrylamide (ACR) in the retina and to assess whether selenium (Se) has protective potential in experimental oral intoxication with ACR. METHODS:Sixty Wistar age matched-albino rats (3mo) weighing 195-230 g comprised of both s...

journal_title：International journal of ophthalmology

authors： Ali MA,Aly EM,Elawady AI

更新日期：2014-08-18 00:00:00

abstract：AIM:To study the effects of gender, eye side and age on anterior chamber measurements; To compare the anterior chamber parameters between glaucoma and normal subjects. METHODS:A total of 169 patients (299 eyes), of which 122 normal subjects (218 eyes), 24 cases (39 eyes) with primary angle-closure glaucoma (PACG) and ...

journal_title：International journal of ophthalmology

authors： Zou X,Duan XC,Zhong Q

更新日期：2010-01-01 00:00:00

abstract：AIM:To investigate the relationship between C-reactive protein (CRP) and diabetic retinopathy (DR) in a cohort of Chinese patients with type 2 diabetes mellitus (T2DM). METHODS:Community-based observational cohort study. There were 1131 participants recruited from November 2009 to September 2011 in Desheng community i...

journal_title：International journal of ophthalmology

authors： Yang XF,Deng Y,Gu H,Lim A,Snellingen T,Liu XP,Wang NL,Domalpally A,Danis R,Liu NP

更新日期：2016-01-18 00:00:00

abstract：AIM:To study the histopathological changes in the retina and flash electroretinogram (F-ERG) features of ozone-treated streptozotocin (STZ)-induced diabetic rats. METHODS:Seventy male Sprague Dawley rats were grouped as follows: blank group (GB, n=10), model control group (GM, n=18), ozone group (GO3, n=19), and oxyge...

journal_title：International journal of ophthalmology

authors： Xie TY,Li Q,Chen XY

更新日期：2016-06-18 00:00:00

abstract：AIM:To explore the correlation between several blood cell-associated inflammatory indices including mean platelet volume (MPV), platelet distribution width (PDW), neutrophil to lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR), and the presence and severity of diabetic retinopathy (DR). METHODS:We searched fo...

journal_title：International journal of ophthalmology

authors： Luo WJ,Zhang WF

更新日期：2019-02-18 00:00:00

abstract：AIM:To investigate clinical characteristics of asymptomatic Terson syndrome and its clinical impact in patients with aneurysmal subarachnoid hemorrhage (SAH). METHODS:This retrospective, interventional study included 31 patients with aneurysmal SAH, and the medical records were reviewed. In addition to baseline charac...

journal_title：International journal of ophthalmology

authors： Kang HM,Cho JM,Kim SY,Choi JH

更新日期：2020-02-18 00:00:00

abstract：AIM:To study the effect of senescence marker protein 30 (SMP30) on the proliferation and apoptosis of human lens epithelial cell (HLEC) SRA01/04. METHODS:SMP30 overexpression (OE) and knock down (KD) type cell lines were cultivated by using two groups regucalcin (RGN; SMP30) lentiviral vectors (LV-RGN, LV-RGN-RNAi) an...

journal_title：International journal of ophthalmology

authors： Chen X,Li SM,Li YW,Han ZH,Liang H

更新日期：2018-04-18 00:00:00

abstract：AIM:To describe the clinical characteristics and late results of patients with retinopathy of prematurity (ROP) treated with "6h cryotherapy". METHODS:Out of 1252 infants screened for ROP, 52 patients were treated with temporal 6h cryotherapy from 1997 to 2005 were recalled to our clinic. Among these 23 patients were ...

journal_title：International journal of ophthalmology

authors： Cerman E,Ozarslan Ozcan D,Celiker H,Eraslan M,Sahin O,Kazokoglu H

更新日期：2016-04-18 00:00:00

abstract：:Myopia, a worldwide condition, is a multifactorial disease resulting in many ocular complications. Early onset of myopia has a great tendency to develop high myopia and pathological myopia later in life. The pathophysiology and progression of myopia is still unclear. Owing to its involving in visual function, optic di...

journal_title：International journal of ophthalmology

authors： Pan T,Su Y,Yuan ST,Lu HC,Hu ZZ,Liu QH

更新日期：2018-05-18 00:00:00

abstract：AIM:To investigate the fundus manifestations and human immunodeficiency virus (HIV) viral loads of acquired immune deficiency syndrome (AIDS) patients before and after highly active antiretroviral therapy (HAART). METHODS:This retrospective study included 21 AIDS patients (42 eyes) who presented to the Department of O...

journal_title：International journal of ophthalmology

authors： Di Y,Zhao XY,Ye JJ,Li B,Ma N

更新日期：2019-09-18 00:00:00

abstract：AIM:To investigate the effect of broccoli sprouts juice in preventing lens protein aggregation in diabetic rat model. METHODS:Totally 25 male Wistar rats were divided into negative control group, diabetic group without juice treatment as positive control and diabetic group given broccoli sprouts juice 0.25, 0.5 and 1 ...

journal_title：International journal of ophthalmology

authors： Puspitasari A,Handayani N

更新日期：2019-09-18 00:00:00

abstract：AIM:To evaluate the neuroprotective effect of rosuvastatin, in a rat experimental glaucoma model. METHODS:Ocular hypertension was induced in right eyes of Long-Evans rats (n=30) by cauterization of three episcleral veins. Left eyes were defined as controls. Rats were divided into five groups: oral rosuvastatin, intrav...

journal_title：International journal of ophthalmology

authors： Unlu M,Aktas Z,Gocun PU,Ilhan SO,Hasanreisoglu M,Hasanreisoglu B

更新日期：2016-03-18 00:00:00

abstract：AIM:To investigate the expression of the v-raf-1 murine leukemia viral oncogene homolog 1 (Raf-1) and its role in the innate immune response of human corneal epithelial cells (HCECs) infected by Aspergillus fumigatus. METHODS:HCECs were cultured in vitro. They were randomly divided into 4 groups, including control gro...

journal_title：International journal of ophthalmology

authors： Zhao GQ,Lin J,Hu LT,Yin XN,Wang Q,Xu Q,Li H

更新日期：2016-10-18 00:00:00

abstract：AIM:To evaluate the effect of the application of sodium hyaluronate on the operation of suturing the corneal perforation. METHODS:Sodium hyaluronate was used in the operation of suturing the corneal perforation in 76 patients to form the anterior chamber, protect eye tissues and separate the anterior iris synechia. R...

journal_title：International journal of ophthalmology

authors： Jiang T,Jiang J,Zhou Y,Zhao GQ,Yang SS,Li H,Shen L

更新日期：2010-01-01 00:00:00

abstract：:There are many vision threatening diseases of the eye affecting millions of people worldwide. In this article, we are summarizing potential role of various matrix metalloproteinases (MMPs); the Zn (2+)-dependent endoproteases in eye health along with pathogenesis of prominent ocular diseases such as macular degenerati...

journal_title：International journal of ophthalmology

authors： Singh M,Tyagi SC

更新日期：2017-08-18 00:00:00

abstract：AIM:To determine whether the PI3K/AKT/mTOR pathway is activated in proliferative vitreoretinopathy (PVR) in homo-sapiens. METHODS:The retina of controls and patients with PVR were collected and their levels of PI3K, phospho-AKT, phospho-mTOR, phospho-p70S6k and phospho-4EBP-1 were determined by Western blot. The cultu...

journal_title：International journal of ophthalmology

authors： Cai N,Dai SD,Liu NN,Liu LM,Zhao N,Chen L

更新日期：2012-01-01 00:00:00

abstract：AIM:To identify risk factors for an atherothrombotic event (ATE) among patients who were treated for diabetic macular edema (DME) with intravitreal bevacizumab injections. METHODS:This retrospective study enrolled all consecutive patients with DME who were treated by intravitreal bevacizumab from 2009 through 2016 in ...

journal_title：International journal of ophthalmology

authors： Tiosano A,Hadad A,Yanculovic N

更新日期：2020-09-18 00:00:00

abstract：AIM:To report the clinical outcomes of utilizing a three-layer flap and graft in reconstruction of the lower lid in one session. METHODS:Seventeen patients with total or near total lower eyelid defect were included. The defects were reconstructed in three layers. Posterior lamella was reconstructed by using tarsoconju...

journal_title：International journal of ophthalmology

authors： Rajabi MT,Bazvand F,Hosseini SS,Makateb A,Rajabi MB,Tabatabaie SZ,Abrishami Y

更新日期：2014-06-18 00:00:00

abstract：AIM:To evaluate postoperative visual acuity and contrast sensitivity results following deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in patients with keratoconus (KC). METHODS:All the patients' records with KC who had PK or DALK surgery between May 2010 and May 2011 were retrospectively ...

journal_title：International journal of ophthalmology

authors： Akdemir MO,Kandemir B,Sayman IB,Selvi C,Kamil Dogan O

更新日期：2012-01-01 00:00:00

abstract：AIM:To determine whether intravitreal dexamethasone (DEX) implant induces posterior vitreous detachment or not. METHODS:We retrospectively reviewed 810 eyes of 405 patients who underwent intravitreal DEX implantation due to macular edema caused by diabetic and retinal venous occlusion in our clinic. The eyes having no...

journal_title：International journal of ophthalmology

authors： Alpay A

更新日期：2019-08-18 00:00:00

abstract：AIM:To analyze the clinical manifestation of Alport syndrome, especially the ocular features. METHODS:The physical, ophthalmologic and audiologic examination results of thirty-two patients with Alport syndrome were analyzed retrospectively. RESULTS:Thirty (93.7%) patients had some family history. All patients had ren...

journal_title：International journal of ophthalmology

authors： Xu JM,Zhang SS,Zhang Q,Zhou YM,Zhu CH,Ge J,Wang L

更新日期：2010-01-01 00:00:00

abstract：AIM:To compare and evaluate the clinical outcomes of deep anterior lamellar keratoplasty (DALK) and excimer laser assisted anterior lamellar keratoplasty (ELLK) in eyes with keratoconus. METHODS:In this study, 57 eyes of 56 patients operated between 2013 to 2017 were included. Thirty-one eyes underwent big-bubble DALK...

journal_title：International journal of ophthalmology

authors： Ceylanoglu KS,Aydin B,Ozmen MC

更新日期：2019-04-18 00:00:00

abstract：:Diabetic retinopathy (DR) is one of the most common and challenging ocular complications of diabetes mellitus. As a chronic, progressive ocular disease that poses a serious threat to vision, DR has gradually become a leading cause of blindness worldwide. Emerging evidence points to an important role of endoplasmic ret...

journal_title：International journal of ophthalmology

authors： Kong DQ,Li L,Liu Y,Zheng GY

更新日期：2018-10-18 00:00:00

abstract：AIM:To investigate the effect of age on reading acuity and reading speed in attaining text information in healthy eyes. METHODS:Reading acuity, critical print size, reading speed and maximum reading speed were measured in groups of 40 children (8 to 12 years old), 40 teenagers (13 to 19 years old), 40 young adults (20...

journal_title：International journal of ophthalmology

authors： Chen AH,Khalid NM,Buari NH

更新日期：2019-07-18 00:00:00

abstract：AIM:To investigate the incidence and the predisposing factors of anterior chamber (AC) gas bubbles during femtosecond laser (FS) flap creation for laser in situ keratomileusis (LASIK). METHODS:All patients who underwent FS-LASIK surgery at CMU LASIK Center between January 2013 and May 2016 were retrospective reviewed....

journal_title：International journal of ophthalmology

authors： Niparugs M,Supalaset S,Tangmonkongvoragul C,Tananuvat N,Chaidaroon W,Ausayakhun S

更新日期：2020-08-18 00:00:00