Promotion of axon regeneration and inhibition of astrocyte activation by alpha A-crystallin on crushed optic nerve.

abstract：AIM:To demonstrate local dry vitrectomy combined with segmental scleral buckling and viscoelastic tamponade for the treatment of partial rhegmatogenous retinal detachment (RRD) with local vitreous traction in patients at high-risk for proliferative vitreoretinopathy (PVR). METHODS:Eleven eyes of 11 patients were retro...

journal_title：International journal of ophthalmology

authors： Fei P,Jin HY,Zhang Q,Peng J,Li JK,Lyu J,Tian T,Lu ZP,Li J,Zhao PQ

更新日期：2020-11-18 00:00:00

abstract：AIM:To investigate mitochondrial factors associated with Leber hereditary optic neuropathy (LHON) through complete sequencing and analysis of the mitochondrial genome of Chinese patients with this disease. METHODS:Two unrelated southern Chinese families with LHON and 10 matched healthy controls were recruited, and the...

journal_title：International journal of ophthalmology

authors： Shu L,Zhang YM,Huang XX,Chen CY,Zhang XN

更新日期：2012-01-01 00:00:00

abstract：AIM:To investigate the association of Manganese superoxide dismutase (MnSOD) Val16Ala polymorphism with diabetic retinopathy (DR). METHODS:PubMed, Embase, China National Knowledge Infrastructure, and Wanfang databases were searched. The pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to eva...

journal_title：International journal of ophthalmology

authors： Huang L,Lyu J,Liu QP,Chen C,Wang T

更新日期：2017-04-18 00:00:00

abstract：AIM:To describe the clinical features of congenital double elevator palsy (CDEP) and to evaluate various surgical outcomes between the standard Knapp and augmented Knapp procedures, based on improvements in primary eye position and ocular motility. METHODS:Twenty-two patients with CDEP at Shanghai Children's Hospital ...

journal_title：International journal of ophthalmology

authors： Luo WT,Qiao T,Ye HY,Li SH,Chen QL

更新日期：2018-08-18 00:00:00

abstract：AIM:To study the effect of different flap sizes on visual acuity, refractive outcomes, and aberrations after femtosecond laser for laser in situ keratomileusis (LASIK). METHODS:In each of the forty patients enrolled, 1 eye was randomly assigned to receive treatment with a 8.1mm diameter corneal flap, defined as the sm...

journal_title：International journal of ophthalmology

authors： Zhang YL,Liu L,Cui CX,Hu M,Li ZN,Cao LJ,Jing XH,Mu GY

更新日期：2013-10-18 00:00:00

abstract：AIM:To examine the cytotoxic effect of pilocarpine, an anti-glaucoma drug, on human corneal stromal (HCS) cells and its underlying cytotoxic mechanisms using an in vitro model of non-transfected HCS cells. METHODS:After HCS cells were treated with pilocarpine at a concentration from 0.15625 g/L to 20.0 g/L, their morp...

journal_title：International journal of ophthalmology

authors： Yuan XL,Wen Q,Zhang MY,Fan TJ

更新日期：2016-04-18 00:00:00

abstract：AIM:To evaluate the effect of the application of sodium hyaluronate on the operation of suturing the corneal perforation. METHODS:Sodium hyaluronate was used in the operation of suturing the corneal perforation in 76 patients to form the anterior chamber, protect eye tissues and separate the anterior iris synechia. R...

journal_title：International journal of ophthalmology

authors： Jiang T,Jiang J,Zhou Y,Zhao GQ,Yang SS,Li H,Shen L

更新日期：2010-01-01 00:00:00

abstract：AIM:To evaluate the clinical effect and complications of two different filling materials (aerocyst urethral catheter and expansion sponges) applying in external dacryocystorhinostomy (EXT-DCR) and compare their advantages and disadvantages. METHODS:A retrospective study was made in the period from April, 1 2000 to Apr...

journal_title：International journal of ophthalmology

authors： Shao Y,Yu Y,Pei CG,Zhou Q,Dong WJ,Qu Y,Yang L,Gao GP

更新日期：2011-01-01 00:00:00

abstract：AIM:To describe a series of Italian patients with orbital metastasis focusing on the outcomes in relation to the different primary site of malignancy. METHODS:Retrospective chart review of 93 patients with orbital metastasis collected in a tertiary referral centre in a period of 38y and review of literature. RESULTS:...

journal_title：International journal of ophthalmology

authors： Magliozzi P,Strianese D,Bonavolontà P,Ferrara M,Ruggiero P,Carandente R,Bonavolontà G,Tranfa F

更新日期：2015-10-18 00:00:00

abstract：AIM:To evaluate the visual outcomes of simultaneous non-topography guided photorefractive keratectomy (PRK) and corneal collagen cross-linking (CXL) in eyes with keratoconus 5y after the procedure. METHODS:Prospective, interventional, non-randomized, and non-controlled case series design was used. Sixty eyes of 30 pat...

journal_title：International journal of ophthalmology

authors： Al-Amri AM

更新日期：2018-01-18 00:00:00

abstract：AIM:To investigate the variation of IGSF3 gene in three families with congenital absence of lacrimal puncta and canaliculi, and to lay a foundation for further research on the pathogenic gene of congenital lacrimal duct agenesis. METHODS:The members of the three families were recruited. The ophthalmologic examinations...

journal_title：International journal of ophthalmology

authors： Wang F,Tao H,Han C,Bai F,Wang P,Zhou XB,Wang LH,Liu C

更新日期：2020-09-18 00:00:00

abstract：:Most of the ocular tumors have poor prognosis, and they remain a difficult problem in the area of ophthalmology. With the rapid development of molecular biology and immunologic techniques and the deep research on ocular tumor related genes, it becomes possible to diagnose and treat malignant tumors from the molecular ...

journal_title：International journal of ophthalmology

authors： Ning Q,Hou L,Meng M,Pan BR,Zhao XH

更新日期：2011-01-01 00:00:00

abstract：AIM:To detect the association between macular pigment optical density (MPOD), which reflects the antioxidant ability of retina, and diabetic retinopathy (DR) and to investigate the correlated factors of MPOD. METHODS:Totally 435 subjects of urban Chinese were recruited to the study and divided into 3 groups: non-diabe...

journal_title：International journal of ophthalmology

authors： She CY,Gu H,Xu J,Yang XF,Ren XT,Liu NP

更新日期：2016-10-18 00:00:00

abstract：AIM:To review imaging characteristics and surgical outcomes of orbital neurilemmoma. METHODS:Retrospective review of 21 patients with orbital neurilemmoma managed at the Zhongshan Ophthalmic Center of Sun Yat-sen University from June 2005 to December 2016. All patients underwent surgical excision following preoperativ...

journal_title：International journal of ophthalmology

authors： Chen MH,Yan JH

更新日期：2019-07-18 00:00:00

abstract：AIM:To observe the changes of basic fibroblast growth factor (bFGF) content in anterior chamber before and after extra capsular lens extraction for investigating the mechanism of low molecular weight heparin (LMWH) inhibiting anterior chamber inflammation. METHODS:Eighty-four rabbits were randomly divided into control...

journal_title：International journal of ophthalmology

authors： Wang JM,Xiong L,Xiong QC,Fan YZ

更新日期：2012-01-01 00:00:00

abstract：AIM:To compare conventional slow equilibrium cooling and directional freezing (DF) by gauze package for cryopreservation of human umbilical vein endothelial cells (HUVECs). METHODS:HUVECs were randomly assigned to conventional freezing (CF) and DF by gauze package group. The two groups of HUVECs were incubated with a ...

journal_title：International journal of ophthalmology

authors： Qi B,Ji QS,Hou GH,Li L,Cao XF,Wu J

更新日期：2014-10-18 00:00:00

abstract：AIM:To evaluate the effect of incision types for Artisan phakic intraocular lens (PIOL) implantation on ocular higher-order aberrations (HOAs). METHODS:A retrospective review was conducted of the patients who had undergone Artisan PIOL implantation for the correction of myopia and followed up for at least 6mo. Patient...

journal_title：International journal of ophthalmology

authors： Park YM,Choi BJ,Lee JS

更新日期：2016-12-18 00:00:00

abstract：AIM:To compare the best corrected visual acuity (BCVA) between Verteporfin with photodynamic therapy (PDT) and intravitreal anti-vascular endothelial growth factor (anti-VEGF) in patients with myopic choroidal neovascularization (CNV). METHOD:Published literature from Medline, Premedline, Embase and the Cochrane Libra...

journal_title：International journal of ophthalmology

authors： Zhou L,Xing YQ,Li T,Li Y,Song XS,Li JZ

更新日期：2014-08-18 00:00:00

abstract：AIM:To assess the anatomical and visual outcome of idiopathic macular holes greater than 1000 µm using the inverted internal limiting membrane flap technique. METHODS:This retrospective case series included 5 eyes of 5 patients with idiopathic macular hole with base diameter greater than 1000 µm who underwent inverted...

journal_title：International journal of ophthalmology

authors： Khodani M,Bansal P,Narayanan R,Chhablani J

更新日期：2016-08-18 00:00:00

abstract：AIM:To observe changes in the content of matrix metalloproteinases (MMPs) in the corneal stroma after corneal cross-linking (CXL) in rabbits, and further explore the corneal pathophysiological process after CXL. METHODS:Forty-two rabbits (42 eyes) were randomly divided into seven groups. One group served as the contro...

journal_title：International journal of ophthalmology

authors： Jia HZ,Pang X,Peng XJ

更新日期：2021-01-18 00:00:00

abstract：AIM:To compare the clinical results of femtosecond (FS) laser in situ keratomileusis (LASIK) in high myopic patients and low myopic patients. METHODS:This study included 212 myopic eyes undergoing LASIK using a VisuMax 500kHz FS laser. All treated eyes were assigned to one of two groups according to preoperative manif...

journal_title：International journal of ophthalmology

authors： Park SH,Che CY,Kim SI,Park CY,Lee JH,Kim YH,Jung JW,Lee JS,Lee JE

更新日期：2020-11-18 00:00:00

abstract：AIM:To describe the complex, overlapping phenotype of four Chinese patients with inherited retinal dystrophies (IRDs) who harbored two pathogenic genes simultaneously. METHODS:This retrospective study included 4 patients affected with IRDs. Medical and ophthalmic histories were obtained, and clinical examinations were...

journal_title：International journal of ophthalmology

authors： Liu XZ,Tao TC,Qi H,Feng SN,Chen NN,Zhao L,Ma ZZ,Li GL,Yang LP

更新日期：2020-02-18 00:00:00

abstract：AIM:To translate the Glaucoma Quality of Life-15 (GQL-15) to Serbian language and asses its validity and reliability in the population of Serbian patients. METHODS:The study included 177 glaucoma patients. Clinical parameters (visual acuity, mean defect and square root of loss variance of visual field) and socio-demog...

journal_title：International journal of ophthalmology

authors： Sencanic I,Gazibara T,Dotlic J,Stamenkovic M,Jaksic V,Bozic M,Grgurevic A

更新日期：2018-10-18 00:00:00

abstract：AIM:To evaluate the surgical treatment and visual outcomes of eyes with cataract and persistent hyperplastic primary vitreous (PHPV). METHODS:This retrospective study included patients with cataract and PHPV treated with various strategies. Anterior PHPV was treated using phacoemulsification with underwater electric c...

journal_title：International journal of ophthalmology

authors： Li L,Fan DB,Zhao YT,Li Y,Cai FF,Zheng GY

更新日期：2017-03-18 00:00:00

abstract：AIM:To explore the role of IgG4 serology in identifying common orbital lymphoproliferative disorders. METHODS:Eighty-one patients with orbital lymphoproliferative diseases were treated in the Department of Ocular Oncology, Beijing Tongren Hospital, Capital Medical University between September 2010 and December 2012. S...

journal_title：International journal of ophthalmology

authors： Li J,Ma JM,Ge X

更新日期：2016-02-18 00:00:00

abstract：:Retinoblastoma (RB) is the most common intraocular cancer of infancy and childhood. This cancer is initiated by mutation on RB1, the tumor suppressor gene that is responsible for the regulation of both cell cycle and gnome stability in retinal cells. Patients with a constitutional mutation on RB1 can be inherited. RB ...

journal_title：International journal of ophthalmology

authors： Luo C,Deng YP

更新日期：2013-06-18 00:00:00

abstract：AIM:To explore the roles of phospholipids and sphingolipids in the inflammatory process of uveitis. METHODS:Aqueous humor (AH) and the retina were obtained from endotoxin-induced uveitis (EIU) rats during the acute inflammation stage (24h after endotoxin injection). Lipids were extracted using a modified Bligh and Dye...

journal_title：International journal of ophthalmology

authors： Wang HY,Wang Y,Zhang Y,Wang J,Xiong SY,Sun Q

更新日期：2018-05-18 00:00:00

abstract：AIM:To evaluate the repeatability of an optical device for measuring the Zernike coefficients of toric intraocular lenses (IOLs) and assess whether its toricity has any impact in its repeatability. METHODS:An experienced technician used the NIMO TR1504 to measure the Zernike coefficients 30 times for an aperture of 4....

journal_title：International journal of ophthalmology

authors： Ferrer-Blasco T,Domínguez-Vicent A,García-Lázaro S,Díez-Ajenjo MA,Alfonso JF,Esteve-Taboada JJ

更新日期：2018-07-18 00:00:00

abstract：AIM:To investigate the effects of transforming growth factor β2 (TGF-β2) and connective tissue growth factor (CTGF) on transdifferentiation of human lens epithelial cells (HLECs) cultured in vitro and synthesis of extracellular matrix (ECM). METHODS:HLECs were treated with TGF-β2 (0, 0.5, 1.0, 5, 10µg/L) and CTGF (0, ...

journal_title：International journal of ophthalmology

authors： Pei C,Ma B,Kang QY,Qin L,Cui LJ

更新日期：2013-12-18 00:00:00

abstract：AIM:To observe the curative effect of bandage contact lens in neurogenic keratitis. METHODS:Twenty cases of neurogenic keratitis were studied at the Department of Ophthalmology, the first Affiliated Hospital of China Medical University, between October 2012 and June 2013. These included 13 males and 7 females, aged fr...

journal_title：International journal of ophthalmology

authors： Sun YZ,Guo L,Zhang FS

更新日期：2014-12-18 00:00:00