Meta-analysis of best corrected visual acuity after treatment for myopic choroidal neovascularisation.

Abstract:

AIM:To compare the best corrected visual acuity (BCVA) between Verteporfin with photodynamic therapy (PDT) and intravitreal anti-vascular endothelial growth factor (anti-VEGF) in patients with myopic choroidal neovascularization (CNV). METHOD:Published literature from Medline, Premedline, Embase and the Cochrane Library from inception until November 2013 were retrieved. All studies evaluating the BCVA between Verteporfin with PDT and intravitreal anti-VEGF for myopic CNV were included. The results were pooled using mean difference (MD), a corresponding 95% confidence interval (CI). RESULTS:Finally, five studies enrolled 349 eyes were included in the meta-analysis. We inferred that the BCVA of myopic CNV after the treatment of anti-VEGF was significantly better compared with Verteporfin with PDT (MD=0.25, 95%CI:0.17-0.33, Z=5.97, P<0.00001). CONCLUSION:This meta-analysis suggests that intravitreal anti-VEGF could have a better BCVA after treatment than Verteporfin with PDT for myopic CNV.

journal_name

Int J Ophthalmol

authors

Zhou L,Xing YQ,Li T,Li Y,Song XS,Li JZ

doi

10.3980/j.issn.2222-3959.2014.04.25

subject

Has Abstract

pub_date

2014-08-18 00:00:00

pages

720-5

issue

4

eissn

2222-3959

issn

2227-4898

pii

ijo-07-04-720

journal_volume

7

pub_type

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