Rac1 activates HIF-1 in laser induced choroidal neovascularization.

abstract：AIM:To compare the efficacy of prophylactic vitrectomy for acute retinal necrosis syndrome(ARN) with routine treatment in Chinese patients, thereby investigate the necessity of prophylactic vitrectomy for ARN. METHODS:Thirty patients (37 eyes) were retrospectively included in this study. The eyes were divided into 2 g...

journal_title：International journal of ophthalmology

authors： Luo YH,Duan XC,Chen BH,Tang LS,Guo XJ

更新日期：2012-01-01 00:00:00

abstract：AIM:To investigate whether the enhanced green fluorescent protein (EGFP) reporter gene could be transferred into human trabecular meshwork (HTM) cells by a HIV-based lentivirus both in vitro and ex vivo. METHODS:The HIV-based lentivirus that contains an EF1-α promoter driving EGFP expression cassette was constructed f...

journal_title：International journal of ophthalmology

authors： Xiang Y,Li B,Wang JM,Li GG,Zhang H,Manyande A,Tian XB

更新日期：2014-12-18 00:00:00

abstract：AIM:To describe and analyze the demographic characteristics and to determine the angiographic features of acute central serous chorioretinopathy(CSCR) in an Egyptian population. METHODS:A series of consecutive patients presenting with acute idiopathic CSCR to Mansoura Ophthalmology Center Mansoura University who under...

journal_title：International journal of ophthalmology

authors： Shahin MM

更新日期：2013-06-18 00:00:00

abstract：:As a non-penetrating glaucoma surgery (NPGS), canaloplasty aims to reconstruct the physiological outflow of aqueous humor by dilating the Schlemm's canal. Ab interno canaloplasty (ABiC), which can reconstruct the natural outflow pathways of aqueous humor in mild-to-moderate primary open angle glaucoma (POAG) patients,...

journal_title：International journal of ophthalmology

authors： Zhang J,Wang NL

更新日期：2019-10-18 00:00:00

abstract：AIM:To describe the clinical characteristics and late results of patients with retinopathy of prematurity (ROP) treated with "6h cryotherapy". METHODS:Out of 1252 infants screened for ROP, 52 patients were treated with temporal 6h cryotherapy from 1997 to 2005 were recalled to our clinic. Among these 23 patients were ...

journal_title：International journal of ophthalmology

authors： Cerman E,Ozarslan Ozcan D,Celiker H,Eraslan M,Sahin O,Kazokoglu H

更新日期：2016-04-18 00:00:00

abstract：AIM:To investigate the expression of the v-raf-1 murine leukemia viral oncogene homolog 1 (Raf-1) and its role in the innate immune response of human corneal epithelial cells (HCECs) infected by Aspergillus fumigatus. METHODS:HCECs were cultured in vitro. They were randomly divided into 4 groups, including control gro...

journal_title：International journal of ophthalmology

authors： Zhao GQ,Lin J,Hu LT,Yin XN,Wang Q,Xu Q,Li H

更新日期：2016-10-18 00:00:00

abstract：AIM:To observe the characteristics of iridociliary cysts in myopic patients and evaluate the influences on the position and safety of implantable collamer lens (ICL) after surgery. METHODS:Totally 270 eyes of 135 patients who underwent ICL surgery for the corrections of myopia were included in this study. Preoperative...

journal_title：International journal of ophthalmology

authors： Chen Q,Qi MY,Lei XH,Zeng QY

更新日期：2020-06-18 00:00:00

abstract：AIM:To investigate the ocular hemodynamic effects of applying a hot compress to the eye. METHODS:The right eyes of five New Zealand white rabbits, both male and female, were hot-compressed for 18min. An independently designed novel ocular contact-type temperature measuring device was used to measure the ocular surface...

journal_title：International journal of ophthalmology

authors： Li TT,Shao GB,Jiang YL,Wang JX,Zhou XR,Ren M,Li LQ

更新日期：2018-12-18 00:00:00

abstract：AIM:To investigate the hematological parameters, biochemical and electrophysiological role of acrylamide (ACR) in the retina and to assess whether selenium (Se) has protective potential in experimental oral intoxication with ACR. METHODS:Sixty Wistar age matched-albino rats (3mo) weighing 195-230 g comprised of both s...

journal_title：International journal of ophthalmology

authors： Ali MA,Aly EM,Elawady AI

更新日期：2014-08-18 00:00:00

abstract：AIM:To evaluate the measurements of anterior segment parameters using three different non-contact optical devices in keratoconus patients. METHODS:A hundred and one eyes of 55 keratoconus patients were enrolled in this study. The mean age was 26.2±8.9 years. The inclusion criteria were keratoconus stage I to III accor...

journal_title：International journal of ophthalmology

authors： Yazıcı AT,Pekel G,Bozkurt E,Yıldırım Y,Pekel E,Demirok A,Yılmaz OF

更新日期：2013-08-18 00:00:00

abstract：AIM:To investigate the healing process after severe corneal epithelial damage in rats treated with mesenchymal stem cells (MSCs) cultured with or without keratinocyte growth factor (KGF-2) and autologous serum (AS) on amniotic membrane (AM). Many patients are blind and devastated by severe ocular surface diseases due t...

journal_title：International journal of ophthalmology

authors： Pınarlı FA,Okten G,Beden U,Fışgın T,Kefeli M,Kara N,Duru F,Tomak L

更新日期：2014-04-18 00:00:00

abstract：AIM:To estimate the potential systemic events during and after retinopathy of prematurity (ROP) screening. METHODS:A prospective and descriptive designed study was conducted to detect the physiologic and pathological changes 24h before, during, and 72h after ROP screening. Control blood pressure (BP), saturation, puls...

journal_title：International journal of ophthalmology

authors： Jiang JB,Zhang ZW,Zhang JW,Wang YL,Nie C,Luo XQ

更新日期：2016-08-18 00:00:00

abstract：AIM:To evaluate the clinical and optical outcomes after clear corneal incision cataract surgery (CICS) with three different incision sizes (1.8, 2.0 and 3.0 mm). METHODS:Eyes of 150 patients with age-related cataract scheduled for coaxial cataract surgery were randomized to three groups: 1.8, 2.0, or 3.0 mm CICS. Intr...

journal_title：International journal of ophthalmology

authors： Yu YB,Zhu YN,Wang W,Zhang YD,Yu YH,Yao K

更新日期：2016-03-18 00:00:00

abstract：AIM:To identify metastatic genes and miRNAs and to investigate the metastatic mechanism of uveal melanoma (UVM). METHODS:GSE27831, GSE39717, and GSE73652 gene expression profiles were downloaded from the Gene Expression Omnibus (GEO) database, and the limma R package was used to identify differentially expressed genes...

journal_title：International journal of ophthalmology

authors： Zhao DD,Zhao X,Li WT

更新日期：2020-07-18 00:00:00

abstract：AIM:To assess and compare the impact of a daily disposable contact lens (CL) with high water content on the ocular surface and comfort of the presbyopic and non-presbyopic population after one day of use. METHODS:Totally 20 presbyopes and 30 non-presbyopes non-contact wearers were fitted with nesofilcon A CLs. CL thic...

journal_title：International journal of ophthalmology

authors： Lorente-Velázquez A,García-Montero M,Gómez-Sanz FJ,Rico Del Viejo L,Hernández-Verdejo JL,Madrid-Costa D

更新日期：2019-04-18 00:00:00

abstract：AIM:To compare the safety and efficacy of phacoemulsification and small incision cataract surgery (SICS) in patients with uveitic cataract. METHODS:In a prospective, randomized multi-centric study, consecutive patients with uveitic cataract were randomized to receive phacoemulsification or manual SICS by either of two...

journal_title：International journal of ophthalmology

authors： Bhargava R,Kumar P,Sharma SK,Kumar M,Kaur A

更新日期：2015-10-18 00:00:00

abstract：AIM:To evaluate ocular penetration of topically applied 1% tigecycline. METHODS:Forty-two New Zealand White rabbits were divided into 3 groups. A 50 µL drop of 1% tigecycline was administered in group 1. In groups 2 and 3, the drop was administered every 15min for 60min (keratitis protocol). Aqueous humor samples in g...

journal_title：International journal of ophthalmology

authors： Sakarya Y,Sakarya R,Ozcimen M,Goktas S,Ozcimen S,Alpfidan I,Ivacık IS,Erdogan E,Cetinkaya S,Bukus A

更新日期：2017-05-18 00:00:00

abstract：AIM:To investigate the fundus manifestations and human immunodeficiency virus (HIV) viral loads of acquired immune deficiency syndrome (AIDS) patients before and after highly active antiretroviral therapy (HAART). METHODS:This retrospective study included 21 AIDS patients (42 eyes) who presented to the Department of O...

journal_title：International journal of ophthalmology

authors： Di Y,Zhao XY,Ye JJ,Li B,Ma N

更新日期：2019-09-18 00:00:00

abstract：AIM:To assess if the included vascular endothelial growth factor (VEGF) polymorphisms rs3025035, rs3025021 and rs2010963 are associated to proliferative retinopathy in a Mexican population with type 2 diabetes mellitus (T2DM). METHODS:A case-control study was conducted in adult individuals with T2DM associated to prol...

journal_title：International journal of ophthalmology

authors： Gonzalez-Salinas R,Garcia-Gutierrez MC,Garcia-Aguirre G,Morales-Canton V,Velez-Montoya R,Soberon-Ventura VR,Gonzalez V,Lechuga R,Garcia-Solis P,Garcia-Gutierrez DG,Garcia-Solis MV,Saenz de Viteri M,Solis-S JC

更新日期：2017-01-18 00:00:00

abstract：AIM:To investigate microRNA-143 expression and effect on suppression of retinoblastoma (RB) cells. METHODS:The expression of microRNA-143 was investigated and compared in normal human retina tissue samples and in RB cell lines of Y79 and Weri1. The microRNA-143 mimics were transfected into the RB cell lines separately...

journal_title：International journal of ophthalmology

authors： Wang LL,Hu HF,Feng YQ

更新日期：2016-11-18 00:00:00

abstract：AIM:To compare the optic disc blood flow of non-arteritic ischemic optic neuropathy (NAION) eyes with normal eyes. METHODS:The optic disc blood flow densities of diagnosed non-acute phase NAION eyes (21 eyes, 14 individuals) and normal eyes (19 eyes, 12 individuals) were detected via Optovue optical coherence tomograp...

journal_title：International journal of ophthalmology

authors： Ling JW,Yin X,Lu QY,Chen YY,Lu PR

更新日期：2017-09-18 00:00:00

abstract：AIM:To investigate peripapillary retinal nerve fiber layer (RNFL), macula and ganglion cell layer thicknesses (GCC) in amblyopic eyes with spectral domain optical coherence tomography (SD-OCT). METHODS:Thirty six patients with a history of unilateral amblyopia and thirty two children who had emmetropia without amblyop...

journal_title：International journal of ophthalmology

authors： Firat PG,Ozsoy E,Demirel S,Cumurcu T,Gunduz A

更新日期：2013-01-01 00:00:00

abstract：AIM:To compare the changes in corneal biomechanics measured by ocular response analyzer (ORA) after 2.2-mm microincision cataract surgery and 3.0-mm standard coaxial phacoemulsification. METHODS:The prospective nonrandomized study comprised eyes with cataract that had 2.2-mm coaxial microincision or 3.0-mm standard in...

journal_title：International journal of ophthalmology

authors： Zhang Z,Yu H,Dong H,Wang L,Jia YD,Zhang SH

更新日期：2016-02-18 00:00:00

abstract：AIM:To assess strabismus control and motor ocular alignment for basic exotropia surgery at 5y follow-up. METHODS:The medical records of 80 consecutive patients aged less than 17 years of age, who underwent surgery for basic exotropia by a single surgeon between years 2000 to 2009 and completed a minimum of 5y follow-u...

journal_title：International journal of ophthalmology

authors： Chew FL,Gesite-de Leon BU,Quah BL

更新日期：2016-07-18 00:00:00

abstract：AIM:To evaluate the visual outcomes and patient satisfaction of two multifocal intraocular lens implantation patterns, with the decision between the two patterns being guided by the patients' choice of visual zones that best suited their lifestyle, or lifestyle zones. METHODS:This is a prospective non-randomized compa...

journal_title：International journal of ophthalmology

authors： Lin HT,Chen WR,Ding ZF,Chen W,Wu CR

更新日期：2012-01-01 00:00:00

abstract：AIM:To compare the effects of intravitreal injection of bevacizumab (IVB) with intravitreal triamcinolone acetonide (IVTA) on the treatment of cystoid macular edema (CME) secondary to retinal vein occlusion (RVO). METHODS:A literature search was conducted using PubMed, the Cochrane Central Register of Controlled Trial...

journal_title：International journal of ophthalmology

authors： Sun Y,Qu Y

更新日期：2015-12-18 00:00:00

abstract：AIM:To investigate a possible trigeminal proprioceptive-oculomotor neural pathway and explore possible synaptic connections between neurons in this pathway. Attempt to bring a new insight to mechanism of Marcus Gunn syndrome (MGS). METHODS:Anterograde and retrograde tract tracing was applied and combined with immunofl...

journal_title：International journal of ophthalmology

authors： Liang HC,Zhang JD,Luo PF,Qiao Y,Su AL,Zhang T,Zhu HN

更新日期：2018-03-18 00:00:00

abstract：:We report on the impact of direct ultraviolet germicidal irradiation (UVGI) on reflective optics, used in the excimer laser system Allegretto Eye-Q. The aim of our work was to confirm our hypothesis based on long-rate observations of obtained anomalies in post-operative results that are attributed to degradation of re...

journal_title：International journal of ophthalmology

authors： Belovickis J,Kurylenka A,Murashko V

更新日期：2017-09-18 00:00:00

abstract：AIM:To determine the incidence of cystoid macular edema (CME) after Descemet's stripping automated endothelial keratoplasty (DSAEK). METHODS:This study included all consecutive patients operated in a Spanish tertiary reference hospital over a period of four years. A total of 55 eyes from 47 patients matched the select...

journal_title：International journal of ophthalmology

authors： Pedemonte-Sarrias E,Salvador Playà T,Sassot Cladera I,Gris O,Ribas Martínez J,García-Arumí J,Giménez N

更新日期：2017-07-18 00:00:00

abstract：AIM:To compare the effect of topically administered and subconjunctivally injected bevacizumab on experimental corneal neovascularization in rats for two weeks after treatment. METHODS:Twenty-eight Sprague-Dawley rats were divided into four groups of 7 animals. Each corneal center of right eye was cauterized with silv...

journal_title：International journal of ophthalmology

authors： Kim J,Kim D,Kim ES,Kim MJ,Tchah H

更新日期：2013-10-18 00:00:00