Abstract:
AIM:To compare the effects of intravitreal injection of bevacizumab (IVB) with intravitreal triamcinolone acetonide (IVTA) on the treatment of cystoid macular edema (CME) secondary to retinal vein occlusion (RVO). METHODS:A literature search was conducted using PubMed, the Cochrane Central Register of Controlled Trials, Web of Science and the Chinese Biomedical Database. The comparison was divided into two groups, group 1 conducted comparison in branch RVO (BRVO) or central RVO (CRVO), group 2 conducted comparison in ischemic-RVO or nonischemic-RVO. Pooled mean differences (MDs) for changes in visual acuity (VA), central macular thickness (CMT) and intraocular pressure (IOP) were calculated in groups at 4, 12 and 24wk after treatment respectively. RESULTS:Eight studies comparing the efficacy of IVB with IVTA were included in the Meta-analysis. In group 1, in BRVO, significant difference was shown on the comparison of CMT at 24wk (MD, -45.66; 95% CI, -76.03 to -15.28; P=0.003), IVB was effective on BRVO for at least 24wk; no significant differences were found in the comparison of VA at each time points (P>0.05 respectively). In CRVO, no significant differences were found in the comparison of VA or CMT between IVB and IVTA at each time points (P>0.05, respectively). In group 2, in ischemic-RVO, significant differences were shown in the comparison of VA (MD, -0.28; 95% CI, -0.42 to -0.14; P<0.0001) and CMT (MD, -86.50; 95% CI, -151.18 to -22.43; P=0.008) at 24wk; In nonischemic-RVO, no significant differences were demonstrated in the comparison of VA or CMT between IVB and IVTA at each time points (P>0.05, respectively). The occurrence of high IOP was much lower in IVB group. CONCLUSION:This Meta-analysis suggested that IVB was effective in decreasing CMT in BRVO for at least 24wk, IVB is more effective on improving VA and reducing CMT in ischemic-RVO. IVB is more promising on RVO than IVTA.
journal_name
Int J Ophthalmoljournal_title
International journal of ophthalmologyauthors
Sun Y,Qu Ydoi
10.3980/j.issn.2222-3959.2015.06.29subject
Has Abstractpub_date
2015-12-18 00:00:00pages
1234-9issue
6eissn
2222-3959issn
2227-4898pii
ijo-08-06-1234journal_volume
8pub_type
杂志文章abstract:AIM:To study plasma levels of vascular endothelial growth factor (VEGF), endothelin-1(ET-1) and nitric oxide (NO) in patients with proliferative diabetic retinopathy (PDR) before and after pan-retinal photocoagulation (PRP). METHODS:Forty patients (23 females and 17 males, mean age 48.5±12.2 years) with PDR without pr...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2010.01.05
更新日期:2010-01-01 00:00:00
abstract::Phacoemulsification is the main gold standard for cataract operation in the developed world together with foldable intraocular lens (IOL) implantation by injection, allowing for stable wound construction and less postoperative astigmatism. It is a safe procedure with high success rate with the advancement in machines,...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.03.34
更新日期:2015-06-18 00:00:00
abstract:AIM:To evaluate the quantitatively changes in lipid layer thickness (LLT) when 3% diquafosol eye drop is used for dry eye patients using the tear film interferometer. METHODS:A total 124 participants (32 males, 92 females; mean age, 28.9y) diagnosed with dry eye disease (DED) received topical instillation of 4 ophthal...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.10.06
更新日期:2019-10-18 00:00:00
abstract:AIM:To analyze and identify the proteomic differences between liquefied after-cataracts and normal lenses by means of liquefied chromatography-tandem mass spectrometry (LC-MS/MS). METHODS:Three normal lenses and three liquefied after-cataracts were exposed to depolymerizing reagents to extract the total proteins. Prot...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.09.02
更新日期:2017-09-18 00:00:00
abstract:AIM:To evaluate chorioretinal responses to intravitreal aflibercept injection (IAI) in patients with acute central serous chorioretinopathy (CSC). METHODS:Seventy-one eyes from 71 patients with symptomatic CSC for less than six months were included. Thirty-five eyes received a single IAI and 36 eyes were observed with...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.12.08
更新日期:2019-12-18 00:00:00
abstract:AIM:To review vision health situation of Iranian community, analyze its determinants, and discuss the adopted improvement strategies by the Iran Ministry of Health and Medical Education (MOHME). METHODS:This was a rapid situation analysis with a qualitative approach in three parts of recognition, orientation and imple...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.01.18
更新日期:2019-01-18 00:00:00
abstract:AIM:To present retinal microstructure, metabolism and function abnormalities in the course of multiple evanescent white dot syndrome (MEWDS) by Heidelberg spectralis modality imaging platform and observe its outcome by EDI-SD-OCT and two wavelength autofluorescence. METHODS:A case of multiple evanescent white dot synd...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2012.05.21
更新日期:2012-01-01 00:00:00
abstract:AIM:To investigate microvascular changes in eyes with central retinal vein occlusion (CRVO) complicated by macular edema before and after intravitreal conbercept injection and evaluate correlations between these changes and best-corrected visual acuity (BCVA) and retinal thickness. METHODS:Twenty-eight eyes of 28 pati...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.05.16
更新日期:2019-05-18 00:00:00
abstract:AIM:To investigate the cytotoxic effect on human corneal epithelial cells (HCECs) and the ability to faciliate corneal epithelial wound healing of carboxymethylcellulose (CMC) and hyaluronic acid (HA). METHODS:HCECs were exposed to 0.5% CMC (Refresh plus(®), Allergan, Irvine, California, USA) and 0.1% and 0.3% HA (Kyn...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.02.01
更新日期:2015-04-18 00:00:00
abstract:AIM:To evaluate the clinical and optical outcomes after clear corneal incision cataract surgery (CICS) with three different incision sizes (1.8, 2.0 and 3.0 mm). METHODS:Eyes of 150 patients with age-related cataract scheduled for coaxial cataract surgery were randomized to three groups: 1.8, 2.0, or 3.0 mm CICS. Intr...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.03.13
更新日期:2016-03-18 00:00:00
abstract:AIM:To evaluate the fractal feature of the retinal vasculature of normal eyes on a stereographic projected and montaged ultra-wide field (UWF) fluorescein angiography (FA). METHODS:Prospective, observational, cross-sectional study. Totally 59 eyes of 31 normal subjects were imaged using the Optos 200Tx. Images obtaine...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2020.07.15
更新日期:2020-07-18 00:00:00
abstract:AIM:To evaluate the effect of strabismus surgery on retinal vessels calibers with digital color fundus photographs. METHODS:Two hundred consecutive strabismus patients underwent surgery, and 118 patients (female/male, 55/63) who finished 6-month follow-up were finally included in this study. Optic disc-centered digita...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.09.16
更新日期:2016-09-18 00:00:00
abstract::With the evolution of cataract surgery from visual rehabilitation to refractive surgery, aspheric intraocular lenses (IOLs) are being increasingly used in the field of ophthalmology. This increased use can be attributed to negative or zero spherical aberrations with unique optical designs, which counteract some of the...
journal_title:International journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.18240/ijo.2019.11.19
更新日期:2019-11-18 00:00:00
abstract:AIM:To compare refractive results, higher-order aberrations (HOAs), contrast sensitivity and dry eye after laser in situ keratomileusis (LASIK) performed with a femtosecond laser versus a mechanical microkeratome for myopia and astigmatism. METHODS:In this prospective, non-randomized study, 120 eyes with myopia receiv...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.04.25
更新日期:2015-08-18 00:00:00
abstract:AIM:To find a stable, inexpensive, and reliable method to produce a rat meibomian gland dysfunction (MGD) model. METHODS:We inserted slim guidewires into the meibomian gland orifices of twelve Brown Norway rats and fulgurized every guidewire to destroy part of the meibomian gland. We then observed the morphological ch...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.07.01
更新日期:2018-07-18 00:00:00
abstract:AIM:To reveal the mechanisms of heat-shock transcription factor 4 (HSF4) mutation-induced cataract. METHODS:GSE22362, including 3 HSF4-null lens and 3 wild-type lens, was obtained from Gene Expression Omnibus database. After data preprocessing, the differentially expressed genes (DEGs) were identified using the limma ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.06.03
更新日期:2018-06-18 00:00:00
abstract:AIM:To identify the genetic defects in a Chinese family with achromatopsia. METHODS:A 2.5-year-old boy, who displayed nystagmus, photophobia, and hyperopia since early infancy, was clinically evaluated. To further confirm and localize the causative mutations in this family, targeted region capture and next-generation ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.05.10
更新日期:2015-10-18 00:00:00
abstract:AIM:To study the effects of curcumin on the secretion of interleukin (IL)-6 and IL-8 by corneal limbus epithelial cells. METHODS:Human corneal limbus epithelial cells were isolated and cultured from donor eyes and irradiated by UVB at different dosages with or without curcumin. MTT test was used for studying the effec...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.06.01
更新日期:2017-06-18 00:00:00
abstract:AIM:To analyze childhood glaucoma regarding its demographics, presentations, different causes and surgical modalities used among patients in Dakahelia and to apply the Childhood Glaucoma Research Network (CGRN) classification retrospectively to evaluate its convenience. METHODS:A retrospective study in which the medic...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.04.23
更新日期:2018-04-18 00:00:00
abstract:AIM:To estimate the potential systemic events during and after retinopathy of prematurity (ROP) screening. METHODS:A prospective and descriptive designed study was conducted to detect the physiologic and pathological changes 24h before, during, and 72h after ROP screening. Control blood pressure (BP), saturation, puls...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.08.11
更新日期:2016-08-18 00:00:00
abstract:AIM:To assess the biosafety of a poly(acrylamide-co-sodium acrylate) hydrogel (PAH) as a 3D-printed intraocular lens (IOL) material. METHODS:The biosafety of PAH was first evaluated in vitro using human lens epithelial cells (LECs) and the ARPE19 cell line, and a cell counting kit-8 (CCK-8) assay was performed to inve...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2020.10.03
更新日期:2020-10-18 00:00:00
abstract:AIM:To compare the anterior segment measurements obtained by rotating Scheimpflug camera (Pentacam) and Scanning-slit topography (Orbscan IIz) in keratoconic eyes. METHODS:A total of 121 patients, 71 males (58.7%) and 50 females (41.3%) (214 eyes) with the diagnosis of keratoconus (KC) were enrolled in this study. Fol...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.02.11
更新日期:2015-04-18 00:00:00
abstract:AIM:To investigate a possible trigeminal proprioceptive-oculomotor neural pathway and explore possible synaptic connections between neurons in this pathway. Attempt to bring a new insight to mechanism of Marcus Gunn syndrome (MGS). METHODS:Anterograde and retrograde tract tracing was applied and combined with immunofl...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.03.06
更新日期:2018-03-18 00:00:00
abstract::The multiple regression formulas and correlation of ocular components with refractive errors are presented by Gaussian optics. The refractive error changing rate for the cornea and lens power, the axial length, anterior chamber depth (ACD) and vitreous chamber depth (VCD) are calculated, including nonlinear terms for ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.05.26
更新日期:2019-05-18 00:00:00
abstract:AIM:To evaluate the impact of 4 different intraocular lenses (IOLs) on posterior capsule opacification (PCO) by comparing the neodymium: yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy rates. METHODS:This retrospective study included 4970 eyes of 4013 cataract patients who underwent phacoemulsification and IOL impl...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.01.22
更新日期:2015-02-18 00:00:00
abstract:AIM:To investigate the published papers of ophthalmology in past ten years and explore the development of ophthalmology. METHORDS:The data of this study retrieved from Science Citation Index Expanded and downloaded online in November 2017, including all the papers with publication year from 2007-2016 were analyzed. Th...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.12.17
更新日期:2017-12-18 00:00:00
abstract:AIM:To evaluate the diagnostic value of B-scan ultrasound and explore the cytological characteristics of patients with vitreoretinal lymphoma (VRL) and primary central nervous system lymphoma (PCNSL). METHODS:The clinical data and pathologic specimens from patients with VRL diagnosed at the North Huashan Hospital from...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.06.20
更新日期:2019-06-18 00:00:00
abstract:AIM:To investigate the effects of transforming growth factor β2 (TGF-β2) and connective tissue growth factor (CTGF) on transdifferentiation of human lens epithelial cells (HLECs) cultured in vitro and synthesis of extracellular matrix (ECM). METHODS:HLECs were treated with TGF-β2 (0, 0.5, 1.0, 5, 10µg/L) and CTGF (0, ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2013.06.03
更新日期:2013-12-18 00:00:00
abstract:AIM:To explore the effect of saturated hydrogen saline on blue light-induced retinal damage in rats. METHODS:The retinal damage of rats was induced by blue light exposure for 6 hours and examined 8 hours, 16 hours and 24 hours after the exposure. One hundred female Sprague-Dawley rats were randomly divided into four g...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2012.02.07
更新日期:2012-01-01 00:00:00
abstract:AIM:To examine the association between the single nucleotide polymorphisms (SNPs) of matrix metalloprotease-9 (MMP-9) gene and primary angle-closure glaucoma (PACG) in a Chinese Han population. METHODS:DNA samples were extracted from peripheral-blood mononuclear cells of 214 PACG patients and 224 healthy controls. Gen...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2014.03.02
更新日期:2014-06-18 00:00:00