Abstract:
AIM:To evaluate the diagnostic value of B-scan ultrasound and explore the cytological characteristics of patients with vitreoretinal lymphoma (VRL) and primary central nervous system lymphoma (PCNSL). METHODS:The clinical data and pathologic specimens from patients with VRL diagnosed at the North Huashan Hospital from 2016 to 2017 were retrospectively reviewed. The patients were diagnosed by slit lamp ophthalmoscopy, B-scan ultrasound, cytology of the vitreous, which was obtained by vitrectomy, and cytokine measurements of interleukin (IL)-10 and IL-6. RESULTS:Twenty-six eyes (19.4%) out of 134 eyes of 67 patients (47 men and 20 women) with PCNSL were diagnosed with VRL by B-scan ultrasound, and 14 eyes (10.4%) were diagnosed by slit lamp ophthalmoscopy. Twenty-four eyes (17.9%) of 17 patients were confirmed as having VRL with cytology. No difference in the association between intracranial lesion location and ocular involvement was found. VRL patients had higher levels of vitreous IL-10 and IL-10/IL-6 when compared with macular hole cases, but the difference was not statistically significant. CONCLUSION:A total of 25.4% of the PCNSL patients had VRL, B-scan ultrasound examination had characteristic features and is recommended over slit lamp ophthalmoscopy for the screening diagnosis of PCNSL with intraocular involvement. Moreover, the cytological and immunohistochemical analyses performed after 25-gauge diagnostic vitrectomy were accurate diagnostic techniques.
journal_name
Int J Ophthalmoljournal_title
International journal of ophthalmologyauthors
Lai J,Chen K,Shi HM,Zhuang L,Zhou X,Xiao JJ,Li Y,Chen BB,Wang QPdoi
10.18240/ijo.2019.06.20subject
Has Abstractpub_date
2019-06-18 00:00:00pages
1001-1007issue
6eissn
2222-3959issn
2227-4898pii
ijo-12-06-1001journal_volume
12pub_type
杂志文章abstract:AIM:To investigate the effect of hypoxia on the proliferation of mouse corneal epithelial cells in vitro. METHODS:Mouse corneal epithelial cells(MCEs) were cultured in normoxia (210mL/L O(2) and 50mL/L CO(2)) and hypoxia (20mL/L O(2) and 50mL/L CO(2)), respectively. Colony forming efficiency (CFE) and cell proliferati...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2011.02.07
更新日期:2011-01-01 00:00:00
abstract:AIM:To investigate the cytotoxic effect of specific T cells from mice with experimental autoimmune uveitis (EAU) as well as their secreted interferon (IFN)-γ and interleukin (IL)-17A on murine photoreceptor (661W) cells. METHODS:An EAU model was established in female mice by injection of interphotoreceptor retinoid bi...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2020.08.02
更新日期:2020-08-18 00:00:00
abstract:AIM:To identify the genetic defects in a Chinese family with achromatopsia. METHODS:A 2.5-year-old boy, who displayed nystagmus, photophobia, and hyperopia since early infancy, was clinically evaluated. To further confirm and localize the causative mutations in this family, targeted region capture and next-generation ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.05.10
更新日期:2015-10-18 00:00:00
abstract:AIM:To anatomically locate the points of minimum corneal thickness and central corneal thickness (pupil center) in relation to the corneal apex. METHODS:Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex (AT), minimum corneal thickness (MT) and corneal thickness at the pupil ce...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2014.04.15
更新日期:2014-08-18 00:00:00
abstract:AIM:To investigate the protective effect and its mechanism of lycium barbarum polysaccharides (LBP) against oxidative stress-induced apoptosis in human retinal pigment epithelial cells. METHODS:ARPE-19 cells, a human retinal pigment epithelial cell lines, were exposed to different concentrations of H2O2 for 24h, then ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.01.02
更新日期:2015-02-18 00:00:00
abstract:AIM:To compare the best corrected visual acuity (BCVA) between Verteporfin with photodynamic therapy (PDT) and intravitreal anti-vascular endothelial growth factor (anti-VEGF) in patients with myopic choroidal neovascularization (CNV). METHOD:Published literature from Medline, Premedline, Embase and the Cochrane Libra...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2014.04.25
更新日期:2014-08-18 00:00:00
abstract::Diabetic retinopathy (DR) is one of the most common and challenging ocular complications of diabetes mellitus. As a chronic, progressive ocular disease that poses a serious threat to vision, DR has gradually become a leading cause of blindness worldwide. Emerging evidence points to an important role of endoplasmic ret...
journal_title:International journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.18240/ijo.2018.10.20
更新日期:2018-10-18 00:00:00
abstract:AIM:To assess the prevalence of meibomian gland dysfunction (MGD) in staffs and faculty members of Sichuan University, China. METHODS:The records of the annually systemic physical examination of 4404 consecutive staffs and faculty members of Sichuan University were analyzed retrospectively. Ocular symptoms and signs o...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2020.10.23
更新日期:2020-10-18 00:00:00
abstract:AIM:To explore the role of IgG4 serology in identifying common orbital lymphoproliferative disorders. METHODS:Eighty-one patients with orbital lymphoproliferative diseases were treated in the Department of Ocular Oncology, Beijing Tongren Hospital, Capital Medical University between September 2010 and December 2012. S...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.02.18
更新日期:2016-02-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.03.11
更新日期:2019-03-18 00:00:00
abstract:AIM:To investigate the ocular hemodynamic effects of applying a hot compress to the eye. METHODS:The right eyes of five New Zealand white rabbits, both male and female, were hot-compressed for 18min. An independently designed novel ocular contact-type temperature measuring device was used to measure the ocular surface...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.12.04
更新日期:2018-12-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.08.01
更新日期:2016-08-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2014.05.05
更新日期:2014-10-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2013.05.06
更新日期:2013-10-18 00:00:00
abstract:AIM:To evaluate clinical outcomes of unilateral implantation of a diffractive multifocal intraocular lens (IOL) in patients with contralateral monofocal IOL. METHODS:Twenty-two patients who already had implantation of a monofocal IOL in unilateral eye underwent implantation of a diffractive multifocal IOL in contralat...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2020.05.07
更新日期:2020-05-18 00:00:00
abstract:AIM:To investigate the healing process after severe corneal epithelial damage in rats treated with mesenchymal stem cells (MSCs) cultured with or without keratinocyte growth factor (KGF-2) and autologous serum (AS) on amniotic membrane (AM). Many patients are blind and devastated by severe ocular surface diseases due t...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2014.02.05
更新日期:2014-04-18 00:00:00
abstract:AIM:To evaluate the long-term response to the fixed combination of dorzolamide/timolol in patients with primary open angle glaucoma (POAG) and the addition of other intraocular pressure (IOP) lowering medications such as prostaglandin analogs and brimonidine. METHODS:A retrospective, non-randomized, and descriptive cl...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2014.02.25
更新日期:2014-04-18 00:00:00
abstract:AIM:To evaluate the surgical treatment and visual outcomes of eyes with cataract and persistent hyperplastic primary vitreous (PHPV). METHODS:This retrospective study included patients with cataract and PHPV treated with various strategies. Anterior PHPV was treated using phacoemulsification with underwater electric c...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.03.11
更新日期:2017-03-18 00:00:00
abstract:AIM:To study the effect of different flap sizes on visual acuity, refractive outcomes, and aberrations after femtosecond laser for laser in situ keratomileusis (LASIK). METHODS:In each of the forty patients enrolled, 1 eye was randomly assigned to receive treatment with a 8.1mm diameter corneal flap, defined as the sm...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2013.05.16
更新日期:2013-10-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.04.23
更新日期:2018-04-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.05.05
更新日期:2018-05-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.07.10
更新日期:2017-07-18 00:00:00
abstract:AIM:To determine the dominant predictive factors of postoperative visual recovery for patients with pituitary adenoma. METHODS:PubMed, Google Scholar, Web of Science and Cochrane Library were searched for relevant human studies, which investigated the prediction of the postoperative visual recovery of patients with pi...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.11.17
更新日期:2017-11-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.02.11
更新日期:2015-04-18 00:00:00
abstract:AIM:To present the rationale, design, methodology, and the baseline data of the Beijing Desheng Diabetic Eye Study (BDDES), and to determine the prevalence of diabetic retinopathy (DR) and possible risk factors in patients with type 2 diabetes mellitus (T2DM) in an urban community of Beijing, China. METHODS:Community-...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.01.19
更新日期:2018-01-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2013.02.04
更新日期:2013-04-18 00:00:00
abstract:AIM:To compare the safety and efficacy of phacoemulsification and small incision cataract surgery (SICS) in patients with uveitic cataract. METHODS:In a prospective, randomized multi-centric study, consecutive patients with uveitic cataract were randomized to receive phacoemulsification or manual SICS by either of two...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
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更新日期:2015-10-18 00:00:00
abstract:AIM:To report the clinical outcomes of utilizing a three-layer flap and graft in reconstruction of the lower lid in one session. METHODS:Seventeen patients with total or near total lower eyelid defect were included. The defects were reconstructed in three layers. Posterior lamella was reconstructed by using tarsoconju...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2014.03.22
更新日期:2014-06-18 00:00:00
abstract:AIM:To describe the clinical and imaging characteristics associated with focal choroidal excavation (FCE), analyze the possible complication, and interpret its probable etiopathogenesis. METHODS:Retrospective descriptive case series of 37 eyes of 32 patients with FCE. Findings of spectral-domain optical coherence tomo...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.03.14
更新日期:2015-06-18 00:00:00
abstract::Glaucoma is the second leading cause of blindness worldwide, and also the most common optic neuropathy. The ultimate cause of vision loss in glaucoma is thought to be retinal ganglion cell (RGC) death. Neuroprotection of RGC is therefore an important goal of glaucoma therapy. Currently, glaucoma treatment relies on ph...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2010.03.01
更新日期:2010-01-01 00:00:00