Heparanase-1 activities in the development of laser induced choroidal neovascularization.

abstract：AIM:To evaluate the role of intravitreal ranubizumab (IVR) in the treatment of familial exudative vitreoretinopathy (FEVR) of stage 2 or greater either as primary or an ajunct to conventional treatments. METHODS:Retrospective, non-controlled clinical study. Thirty patients (37 eyes) diagnosed with FEVR were enrolled. ...

journal_title：International journal of ophthalmology

authors： Lu YZ,Deng GD,Liu JH,Yan H

更新日期：2018-06-18 00:00:00

abstract：AIM:To evaluate corneal topographic changes and surgically induced astigmatism (SIA) after combined phacoemulsification and 25-gauge transconjunctival sutureless vitrectomy (25-G TSV). METHODS:A retrospective study on 96 eyes of 87 patients who underwent combined phacoemulsification and 25-G TSV. The different topogra...

journal_title：International journal of ophthalmology

authors： Sayed KM,Farouk MM,Katome T,Nagasawa T,Naito T,Mitamura Y

更新日期：2017-01-18 00:00:00

abstract：:This study is to investigate the characteristic features of Acanthamoeba keratitis (AK) that differentiating it from herpetic epithelial keratitis (HEK) using anterior segment optical coherence tomography (AS-OCT). Medical records of three eyes of each AK and herpetic keratitis who had AS-OCT examination were reviewed...

journal_title：International journal of ophthalmology

authors： Park YM,Lee JS,Yoo JM,Park JM,Seo SW,Chung IY,Kim SJ

更新日期：2018-08-18 00:00:00

abstract：AIM:To compare the effects of intravitreal injection of bevacizumab (IVB) with intravitreal triamcinolone acetonide (IVTA) on the treatment of cystoid macular edema (CME) secondary to retinal vein occlusion (RVO). METHODS:A literature search was conducted using PubMed, the Cochrane Central Register of Controlled Trial...

journal_title：International journal of ophthalmology

authors： Sun Y,Qu Y

更新日期：2015-12-18 00:00:00

abstract：AIM:To study the effect of Rac1 on the induction of HIF-1α in choroidal neovascularization (CNV) in mice. METHODS:One hundred C57BL/6J mice were laser photocoagulated to induce CNV, fifty mice of that were selected randomly for intravitreal injection of Rac1 inhibitor NSC23766 solution (1µL). After laser photocoagulat...

journal_title：International journal of ophthalmology

authors： Zhang P,Zhang X,Fan JL,Hao XF,Wang YS,Hui YN,Hu D,Zhou J

更新日期：2011-01-01 00:00:00

abstract：AIM:To investigate the cytotoxic effect of specific T cells from mice with experimental autoimmune uveitis (EAU) as well as their secreted interferon (IFN)-γ and interleukin (IL)-17A on murine photoreceptor (661W) cells. METHODS:An EAU model was established in female mice by injection of interphotoreceptor retinoid bi...

journal_title：International journal of ophthalmology

authors： Liu ZF,Zhang F,Guo DD,Pan XM,Bi HS

更新日期：2020-08-18 00:00:00

abstract：AIM:To determine whether the PI3K/AKT/mTOR pathway is activated in proliferative vitreoretinopathy (PVR) in homo-sapiens. METHODS:The retina of controls and patients with PVR were collected and their levels of PI3K, phospho-AKT, phospho-mTOR, phospho-p70S6k and phospho-4EBP-1 were determined by Western blot. The cultu...

journal_title：International journal of ophthalmology

authors： Cai N,Dai SD,Liu NN,Liu LM,Zhao N,Chen L

更新日期：2012-01-01 00:00:00

abstract：AIM:To construct functional human full-thickness corneal replacements. METHODS:Acellular porcine corneal matrix (APCM) was developed from porcine cornea by decellulariztion. The biomechanical properties of anterior-APCM (AAPCM) and posterior-APCM (PAPCM) were checked using uniaxial tensile testing. Human corneal cells...

journal_title：International journal of ophthalmology

authors： Zhang K,Ren XX,Li P,Pang KP,Wang H

更新日期：2019-03-18 00:00:00

abstract：AIM:To compare and evaluate the clinical outcomes of deep anterior lamellar keratoplasty (DALK) and excimer laser assisted anterior lamellar keratoplasty (ELLK) in eyes with keratoconus. METHODS:In this study, 57 eyes of 56 patients operated between 2013 to 2017 were included. Thirty-one eyes underwent big-bubble DALK...

journal_title：International journal of ophthalmology

authors： Ceylanoglu KS,Aydin B,Ozmen MC

更新日期：2019-04-18 00:00:00

abstract：AIM:To explore the roles of phospholipids and sphingolipids in the inflammatory process of uveitis. METHODS:Aqueous humor (AH) and the retina were obtained from endotoxin-induced uveitis (EIU) rats during the acute inflammation stage (24h after endotoxin injection). Lipids were extracted using a modified Bligh and Dye...

journal_title：International journal of ophthalmology

authors： Wang HY,Wang Y,Zhang Y,Wang J,Xiong SY,Sun Q

更新日期：2018-05-18 00:00:00

abstract：AIM:To determine a relation between vitamin D level, which is an inhibitor of angiogenesis, and diabetic retinopathy and its risk factors. METHODS:In a clinic-based cross sectional study two hundred and thirty-five type 2 diabetic patients older than 20y were selected. Patients were classified according to ophthalmolo...

journal_title：International journal of ophthalmology

authors： Bonakdaran S,Shoeibi N

更新日期：2015-04-18 00:00:00

abstract：:Our aim was to report quality of life (QOL) outcomes following Xen45 Gel Stent implantation surgery in patients suffering with primary open angle glaucoma (POAG). A retrospective analysis was performed on all patients who had Xen45 implantation surgery during a 2-year period (Jun, 2016-Apr, 2018). Of 52 consecutive pa...

journal_title：International journal of ophthalmology

authors： Hassan F,Thomson LTM,Toor G,Alfahad Q

更新日期：2019-09-18 00:00:00

abstract：AIM:To evaluate central macular thickness (CMT) and mean choroidal thickness (MCT) in eyes with branch retinal vein occlusion (BRVO), before and after ranibizumab treatment using spectral domain-optical coherence tomography (SD-OCT). METHODS:Forty-two patients with unilateral BRVO and macular edema were included in th...

journal_title：International journal of ophthalmology

authors： Coban-Karatas M,Altan-Yaycioglu R,Ulas B,Sizmaz S,Canan H,Sariturk C

更新日期：2016-05-18 00:00:00

abstract：AIM:To investigate a possible trigeminal proprioceptive-oculomotor neural pathway and explore possible synaptic connections between neurons in this pathway. Attempt to bring a new insight to mechanism of Marcus Gunn syndrome (MGS). METHODS:Anterograde and retrograde tract tracing was applied and combined with immunofl...

journal_title：International journal of ophthalmology

authors： Liang HC,Zhang JD,Luo PF,Qiao Y,Su AL,Zhang T,Zhu HN

更新日期：2018-03-18 00:00:00

abstract：AIM:To investigate the expression of complement factors in the posterior scleral fibroblasts of guinea pigs with negative lens-defocused myopia. METHODS:Eighteen guinea pigs were assigned randomly to two groups: the negative lens-defocused group (NLD group, n=9) and the normal control without treatment group (NC group,...

journal_title：International journal of ophthalmology

authors： Gao TT,Long Q,Yang X

更新日期：2015-08-18 00:00:00

abstract：AIM:To evaluate chorioretinal responses to intravitreal aflibercept injection (IAI) in patients with acute central serous chorioretinopathy (CSC). METHODS:Seventy-one eyes from 71 patients with symptomatic CSC for less than six months were included. Thirty-five eyes received a single IAI and 36 eyes were observed with...

journal_title：International journal of ophthalmology

authors： Jung BJ,Lee K,Park JH,Lee JH

更新日期：2019-12-18 00:00:00

abstract：AIM:To study the effect of different flap sizes on visual acuity, refractive outcomes, and aberrations after femtosecond laser for laser in situ keratomileusis (LASIK). METHODS:In each of the forty patients enrolled, 1 eye was randomly assigned to receive treatment with a 8.1mm diameter corneal flap, defined as the sm...

journal_title：International journal of ophthalmology

authors： Zhang YL,Liu L,Cui CX,Hu M,Li ZN,Cao LJ,Jing XH,Mu GY

更新日期：2013-10-18 00:00:00

abstract：AIM:To evaluate the efficacy and safety of orbital decomposition (OD) surgery in combination with horse chestnut seed extract (HCSE), as compared to OD alone, in patients with thyroid-associated ophthalmopathy (TAO). METHODS:Sixty-two orbits from 62 TAO patients were randomly assigned to OD or OD+HCSE at 1:1 ratio (31...

journal_title：International journal of ophthalmology

authors： Wu YJ,Wei X,Xiao MY,Xiong W

更新日期：2016-06-18 00:00:00

abstract：AIM:To evaluate the clinical effect and complications of two different filling materials (aerocyst urethral catheter and expansion sponges) applying in external dacryocystorhinostomy (EXT-DCR) and compare their advantages and disadvantages. METHODS:A retrospective study was made in the period from April, 1 2000 to Apr...

journal_title：International journal of ophthalmology

authors： Shao Y,Yu Y,Pei CG,Zhou Q,Dong WJ,Qu Y,Yang L,Gao GP

更新日期：2011-01-01 00:00:00

abstract：AIM:To detect the association between macular pigment optical density (MPOD), which reflects the antioxidant ability of retina, and diabetic retinopathy (DR) and to investigate the correlated factors of MPOD. METHODS:Totally 435 subjects of urban Chinese were recruited to the study and divided into 3 groups: non-diabe...

journal_title：International journal of ophthalmology

authors： She CY,Gu H,Xu J,Yang XF,Ren XT,Liu NP

更新日期：2016-10-18 00:00:00

abstract：AIM:To evaluate the clinical and optical outcomes after clear corneal incision cataract surgery (CICS) with three different incision sizes (1.8, 2.0 and 3.0 mm). METHODS:Eyes of 150 patients with age-related cataract scheduled for coaxial cataract surgery were randomized to three groups: 1.8, 2.0, or 3.0 mm CICS. Intr...

journal_title：International journal of ophthalmology

authors： Yu YB,Zhu YN,Wang W,Zhang YD,Yu YH,Yao K

更新日期：2016-03-18 00:00:00

abstract：AIM:To describe a novel technique of creating a landing strip within the trabecular meshwork to guide trabecular micro-bypass stent (iStent) implantation in patients who underwent phacoemulsification. METHODS:Thirty-four eyes from 30 patients who underwent iStent implantation after phacoemulsification from May 2014 to...

journal_title：International journal of ophthalmology

authors： Zheng CX,Moster MR,Gogte P,Dai Y,Manzi RS,Waisbourd M

更新日期：2017-05-18 00:00:00

abstract：AIM:To investigate the variation of IGSF3 gene in three families with congenital absence of lacrimal puncta and canaliculi, and to lay a foundation for further research on the pathogenic gene of congenital lacrimal duct agenesis. METHODS:The members of the three families were recruited. The ophthalmologic examinations...

journal_title：International journal of ophthalmology

authors： Wang F,Tao H,Han C,Bai F,Wang P,Zhou XB,Wang LH,Liu C

更新日期：2020-09-18 00:00:00

abstract：AIM:To evaluate the thickness and volume changes of the choroidal, outer retinal layers (ORL) and retinal pigment epithelium (RPE) in patients with diabetic retinopathy (DR) using optical coherence tomography (OCT) and correlate them with visual acuity. METHODS:We carried out a retrospective observational case series....

journal_title：International journal of ophthalmology

authors： Wang XN,Li ST,Li W,Hua YJ,Wu Q

更新日期：2018-12-18 00:00:00

abstract：AIM:To observe and characterize imaging features of macular and optic disc areas in less than 60-year-old patients with early primary open angle glaucoma (POAG) by optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA), and to evaluate the diagnostic value of OCT and OCTA. METHODS:Total...

journal_title：International journal of ophthalmology

authors： Li YJ,Liu WS,Bai ZC,Cao RX,Ren HH

更新日期：2020-12-18 00:00:00

abstract：AIM:To report the epidemiology and incidence of vitreous hemorrhage and to evaluate risk factors for patients with vitreous hemorrhage (VH) in Taiwan. METHODS:A retrospective population-based study. Analyzing a sample of one million subjects from all enrollees of the Taiwan Health Insurance programme. All data were ob...

journal_title：International journal of ophthalmology

authors： Wang CY,Cheang WM,Hwang DK,Lin CH

更新日期：2017-03-18 00:00:00

abstract：AIM:To assess the prevalence of meibomian gland dysfunction (MGD) in staffs and faculty members of Sichuan University, China. METHODS:The records of the annually systemic physical examination of 4404 consecutive staffs and faculty members of Sichuan University were analyzed retrospectively. Ocular symptoms and signs o...

journal_title：International journal of ophthalmology

authors： Gao JG,Chen J,Tang Y,Chen DN

更新日期：2020-10-18 00:00:00

abstract：AIM:To evaluate the repeatability of an optical device for measuring the Zernike coefficients of toric intraocular lenses (IOLs) and assess whether its toricity has any impact in its repeatability. METHODS:An experienced technician used the NIMO TR1504 to measure the Zernike coefficients 30 times for an aperture of 4....

journal_title：International journal of ophthalmology

authors： Ferrer-Blasco T,Domínguez-Vicent A,García-Lázaro S,Díez-Ajenjo MA,Alfonso JF,Esteve-Taboada JJ

更新日期：2018-07-18 00:00:00

abstract：AIM:To analyze and identify the proteomic differences between liquefied after-cataracts and normal lenses by means of liquefied chromatography-tandem mass spectrometry (LC-MS/MS). METHODS:Three normal lenses and three liquefied after-cataracts were exposed to depolymerizing reagents to extract the total proteins. Prot...

journal_title：International journal of ophthalmology

authors： Ge JJ,Huang YS

更新日期：2017-09-18 00:00:00

abstract：AIM:To reveal the mechanisms of heat-shock transcription factor 4 (HSF4) mutation-induced cataract. METHODS:GSE22362, including 3 HSF4-null lens and 3 wild-type lens, was obtained from Gene Expression Omnibus database. After data preprocessing, the differentially expressed genes (DEGs) were identified using the limma ...

journal_title：International journal of ophthalmology

authors： Tian R,Xu Y,Dou WW,Zhang H

更新日期：2018-06-18 00:00:00