Abstract:
AIM:To analyze childhood glaucoma regarding its demographics, presentations, different causes and surgical modalities used among patients in Dakahelia and to apply the Childhood Glaucoma Research Network (CGRN) classification retrospectively to evaluate its convenience. METHODS:A retrospective study in which the medical files of all glaucoma patients <16 years old presented to Mansoura Ophthalmic Center, Mansoura University from 2014 to 2017, were retrieved and analyzed. Collected data included: age, gender, laterality, visual acuity (VA), refraction, intraocular pressure (IOP), corneal diameter, cup-disc ratio, types and number of surgeries and antiglaucomatous drugs (AGD) at the first and last visit. Prevalence of different subtypes was calculated and means of clinical features were compared. RESULTS:A total of 305 eyes of 207 patients were included classified into 6 groups: primary congenital glaucoma (PCG), juvenile open angle glaucoma (JOAG), glaucoma associated with systemic disease, glaucoma associated with ocular anomalies, acquired glaucoma and glaucoma following cataract surgery. PCG was the predominant type (55.1%) followed by acquired glaucoma (29.5%). Males represented 63.8% of the whole studied patients. Glaucoma associated with ocular anomaly group showed the youngest age at diagnosis (21.9±30.0mo). The shortest corneal diameter was recorded in post cataract group (10.4±0.5 mm). Highest cup-disc ratio was found in the PCG group (P<0.0005). Glaucoma associated with systemic disease presented with the highest baseline IOP (34.5±5.0 mm Hg). All the cases with PCG were treated surgically with 21.8% required more than one surgery. The majority of the patients (74.2%) in the acquired group were treated medically. Combined trabeculotomy-trabeculectomy was the most frequent operation done, accounting for 34.5% of all primary surgeries. Ahmed valve implantation comprised 87% of the secondary surgeries. Acquired glaucoma group had the highest percent of eyes with good final Snellen's VA (69.4%), while glaucoma associated with ocular anomaly group had poorest final VA. CONCLUSION:PCG is the most prevalent type of childhood glaucoma, followed by acquired glaucoma especially traumatic hyphema. Combined trabeculotomy-trabeculectomy and Ahmed valve implantation are the most common surgical interventions. CGRN classification is found to provide a consensus skeleton and is recommended to be integrated in our routine ongoing clinical practice.
journal_name
Int J Ophthalmoljournal_title
International journal of ophthalmologyauthors
Mokbel TH,El Hefney EM,Hagras SM,ALNagdy AA,Badawi AE,Kasem MA,El Shaer SMdoi
10.18240/ijo.2018.04.23subject
Has Abstractpub_date
2018-04-18 00:00:00pages
674-680issue
4eissn
2222-3959issn
2227-4898pii
ijo-11-04-674journal_volume
11pub_type
杂志文章abstract:AIM:To analyze proteomic and signal transduction alterations in irradiated melanoma cells. METHODS:We combined stable isotope labeling with amino acids in cell culture (SILAC) with highly sensitive shotgun tandem mass spectrometry (MS) to create an efficient approach for protein quantification. Protein-protein interac...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2013.03.06
更新日期:2013-06-18 00:00:00
abstract:AIM:To assess the biosafety of a poly(acrylamide-co-sodium acrylate) hydrogel (PAH) as a 3D-printed intraocular lens (IOL) material. METHODS:The biosafety of PAH was first evaluated in vitro using human lens epithelial cells (LECs) and the ARPE19 cell line, and a cell counting kit-8 (CCK-8) assay was performed to inve...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2020.10.03
更新日期:2020-10-18 00:00:00
abstract:AIM:To determine the influence of the dialysis time before kidney transplantation on postoperative ophthalmic complications. METHODS:One hundred and eighty three patients who were given the follow-up after kidney transplantation were selected, including 124 males and 59 females. The dialysis time before kidney transpl...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2012.03.23
更新日期:2012-01-01 00:00:00
abstract:AIM:To investigate extent and nature of visual pathways involvement in children with clinically isolated syndrome (CIS). METHODS:Forty-seven patients (age 11-17y) with CIS, which later proved to be multiple sclerosis (MS) onset, and 30 controls underwent visual evoked potentials (VEP) investigation within 12d from the...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.02.30
更新日期:2015-04-18 00:00:00
abstract::Diabetic retinopathy (DR) is one of the most common and challenging ocular complications of diabetes mellitus. As a chronic, progressive ocular disease that poses a serious threat to vision, DR has gradually become a leading cause of blindness worldwide. Emerging evidence points to an important role of endoplasmic ret...
journal_title:International journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.18240/ijo.2018.10.20
更新日期:2018-10-18 00:00:00
abstract:AIM:To evaluate the visual outcomes of simultaneous non-topography guided photorefractive keratectomy (PRK) and corneal collagen cross-linking (CXL) in eyes with keratoconus 5y after the procedure. METHODS:Prospective, interventional, non-randomized, and non-controlled case series design was used. Sixty eyes of 30 pat...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.01.09
更新日期:2018-01-18 00:00:00
abstract:AIM:To present retinal microstructure, metabolism and function abnormalities in the course of multiple evanescent white dot syndrome (MEWDS) by Heidelberg spectralis modality imaging platform and observe its outcome by EDI-SD-OCT and two wavelength autofluorescence. METHODS:A case of multiple evanescent white dot synd...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2012.05.21
更新日期:2012-01-01 00:00:00
abstract:AIM:To report the surgical technique and efficacy of the tiled transplantation internal limiting membrane (ILM) pedicle flap technique after vitrectomy for 33 patients with large macular hole (MH). METHODS:This study was a prospective noncontrolled interventional study. All patients were treated by vitrectomy, the til...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2019.02.10
更新日期:2019-02-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.01.19
更新日期:2018-01-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.03.11
更新日期:2017-03-18 00:00:00
abstract:AIM:To compare the clinical performance of two types of silicon hydrogel contact lenses used as bandage lenses after LASEK surgery. METHODS:A prospective, double-masked study was conducted on 42 eyes of 21 patients who received binocular LASEK surgeries. The interocular difference in spherical equivalent power was les...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2011.03.22
更新日期:2011-01-01 00:00:00
abstract:AIM:To assess strabismus control and motor ocular alignment for basic exotropia surgery at 5y follow-up. METHODS:The medical records of 80 consecutive patients aged less than 17 years of age, who underwent surgery for basic exotropia by a single surgeon between years 2000 to 2009 and completed a minimum of 5y follow-u...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.07.13
更新日期:2016-07-18 00:00:00
abstract:AIM:To compare refractive results, higher-order aberrations (HOAs), contrast sensitivity and dry eye after laser in situ keratomileusis (LASIK) performed with a femtosecond laser versus a mechanical microkeratome for myopia and astigmatism. METHODS:In this prospective, non-randomized study, 120 eyes with myopia receiv...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.04.25
更新日期:2015-08-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2011.02.17
更新日期:2011-01-01 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.02.07
更新日期:2017-02-18 00:00:00
abstract:AIM:To investigate the expression of the v-raf-1 murine leukemia viral oncogene homolog 1 (Raf-1) and its role in the innate immune response of human corneal epithelial cells (HCECs) infected by Aspergillus fumigatus. METHODS:HCECs were cultured in vitro. They were randomly divided into 4 groups, including control gro...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.10.01
更新日期:2016-10-18 00:00:00
abstract:AIM:To evaluate the neuroprotective effect of rosuvastatin, in a rat experimental glaucoma model. METHODS:Ocular hypertension was induced in right eyes of Long-Evans rats (n=30) by cauterization of three episcleral veins. Left eyes were defined as controls. Rats were divided into five groups: oral rosuvastatin, intrav...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.03.03
更新日期:2016-03-18 00:00:00
abstract:AIM:To determine the risk factors for acute endophthalmitis after cataract extraction in a tertiary care centre in India. METHODS:We performed a nested case control study within a retrospective cohort. The surgical records of all patients with clinically diagnosed endophthalmitis within one month after cataract surger...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2015.06.19
更新日期:2015-12-18 00:00:00
abstract:AIM:To report various ocular injuries caused by durian fruit. METHODS:Three cases of ocular injuries were described in young patients, due to accidental fall of durian fruit on the forehead and face, while they were taking rest/sleeping /playing under the durian tree. RESULTS:The ocular injuries observed were lacerat...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2012.04.25
更新日期:2012-01-01 00:00:00
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journal_title:International journal of ophthalmology
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2016.08.22
更新日期:2016-08-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.02.07
更新日期:2018-02-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2014.06.02
更新日期:2014-12-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.06.01
更新日期:2017-06-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.05.05
更新日期:2018-05-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2018.04.13
更新日期:2018-04-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.3980/j.issn.2222-3959.2014.03.12
更新日期:2014-06-18 00:00:00
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journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.10.07
更新日期:2017-10-18 00:00:00
abstract:AIM:To construct functional human full-thickness corneal replacements. METHODS:Acellular porcine corneal matrix (APCM) was developed from porcine cornea by decellulariztion. The biomechanical properties of anterior-APCM (AAPCM) and posterior-APCM (PAPCM) were checked using uniaxial tensile testing. Human corneal cells...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
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更新日期:2019-03-18 00:00:00
abstract:AIM:To compare of lens oxidative damage induced by vitrectomy and/or hyperoxia in rabbit. METHODS:Sixteen New Zealand rabbits (2.4-2.5 kg) were randomly divided into two groups (Group A, n=12; Group B, n=4). In Group A, the right eyes were treated with vitrectomy and systemic hyperoxia (oxygen concentration: 80%-85%, ...
journal_title:International journal of ophthalmology
pub_type: 杂志文章
doi:10.18240/ijo.2017.01.02
更新日期:2017-01-18 00:00:00