当前位置： SCI文献检索 > International Journal of Ophthalmology期刊下所有文献 > Modified ulcer debridement in the treatment of the superficial fungal infection of the cornea.

Modified ulcer debridement in the treatment of the superficial fungal infection of the cornea.

Abstract：

AIM:To evaluate the efficacy of modified corneal ulcer debridement in superficial fungal keratitis unresponsive to medications. METHODS:A total of 209 patients (209 eyes) with fungal keratitis, involving no more than 50% of the stromal depth and not responding to antifungal agents for 2wk, were recruited in this retrospective, noncomparative study. The patients were treated with modified corneal ulcer debridement. All visible corneal infiltrates were removed under an operating microscope to obtain a clean stromal bed and smooth incised edges. Antifungal drugs were used immediately after surgery. Healing time of the ulcers was recorded. Fungal recurrence, visual acuity, corneal thickness and risk factors for treatment failure were monitored. RESULTS:The follow-up was 13.6±5.8mo. The corneal ulcers healed in 195 of 209 eyes (93.3%), with a mean healing time of 8.4±6.8d. The other 14 eyes were further treated by penetrating keratoplasty (PK) (1 eye), anterior lamellar keratoplasty (LK) (7 eyes), conjunctival flap covering (4 eyes) or amniotic membrane transplantation (2 eyes). The best corrected visual acuity (BCVA) was ≥20/70 in 80.3% of the eyes, ≥20/40 in 56.9% of the eyes, and ≥20/25 in 27.3% of the eyes. The corneas at the lesions became thinner, but all in the safe range. No fungal recurrence or corneal ectasis developed during the follow-up. The risk of treatment failure was higher in patients with preoperative hypopyon (P=0.036) and ever using steroid (P=0.025). CONCLUSION:Modified surgical debridement is a simple and effective method for the treatment of superficial fungal infection of the cornea, with improved visual acuity and no recurrence. Such an intervention in time can rapidly control fungal infection and largely shorten corneal ulcer healing time.

journal_name

Int J Ophthalmol

journal_title

International journal of ophthalmology

authors

Wang JY,Wang DQ,Qi XL,Cheng J,Xie LX

doi

10.18240/ijo.2018.02.07

subject

Has Abstract

pub_date

2018-02-18 00:00:00

pages

223-229

issue

2

eissn

2222-3959

issn

2227-4898

pii

ijo-11-02-223

journal_volume

11

pub_type

杂志文章

相关文献

International Journal of Ophthalmology文献大全
  • Optic disc and peripapillary changes by optic coherence tomography in high myopia.

    abstract：:Myopia, a worldwide condition, is a multifactorial disease resulting in many ocular complications. Early onset of myopia has a great tendency to develop high myopia and pathological myopia later in life. The pathophysiology and progression of myopia is still unclear. Owing to its involving in visual function, optic di...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章,评审

    doi：10.18240/ijo.2018.05.25

    authors： Pan T,Su Y,Yuan ST,Lu HC,Hu ZZ,Liu QH

    更新日期：2018-05-18 00:00:00

  • Laser therapy versus intravitreal injection of anti-VEGF agents in monotherapy of ROP: a Meta-analysis.

    abstract：AIM:To compare the efficacy and safety between laser therapy and anti-vascular endothelial growth factor (VEGF) agents intravitreal injection monotherapy in type-1 retinopathy of prematurity (ROP) and aggressive posterior retinopathy of prematurity (APROP). METHODS:A systematic literature search was performed in PubMe...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2020.05.17

    authors： Wang SD,Zhang GM,Shenzhen Screening for Retinopathy of Prematurity Cooperative Group.

    更新日期：2020-05-18 00:00:00

  • Preliminary report on screening IGSF3 gene mutation in families with congenital absence of lacrimal puncta and canaliculi.

    abstract：AIM:To investigate the variation of IGSF3 gene in three families with congenital absence of lacrimal puncta and canaliculi, and to lay a foundation for further research on the pathogenic gene of congenital lacrimal duct agenesis. METHODS:The members of the three families were recruited. The ophthalmologic examinations...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2020.09.02

    authors： Wang F,Tao H,Han C,Bai F,Wang P,Zhou XB,Wang LH,Liu C

    更新日期：2020-09-18 00:00:00

  • Anterior lamellar recession for management of upper eyelid cicatricial entropion and associated eyelid abnormalities.

    abstract：AIM:To evaluate the functional and aesthetic outcomes of upper eyelid cicatricial entropion (UCE) correction using anterior lamellar recession (ALR) with addressing the associated conditions including dermatochalasis, brow ptosis, blepharoptosis, and lid retraction. METHODS:Chart review of patients with upper lid cica...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2017.12.07

    authors： Gawdat TI,Kamal MA,Saif AS,Diab MM

    更新日期：2017-12-18 00:00:00

  • Trocar opening: silicone oil removal with phacoemulsification and intraocular lens implantation.

    abstract：AIM:To evaluate the efficacy and safety of a modified technique [trocar opening (TO)] for silicone oil removal (SOR) in combination with phacoemulsification and intraocular lens (IOL) implantation. METHODS:A total of 60 eyes of 60 patients with cataract and silicone oil-filled eyes were enrolled in this study. The pat...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2019.11.09

    authors： Zhang X,Pan YJ,Song ZY

    更新日期：2019-11-18 00:00:00

  • Optical quality of toric intraocular lens implantation in cataract surgery.

    abstract：AIM:To analyze the optical quality after implantation of toric intraocular lens with optical quality analysis system. METHODS:Fifty-two eyes of forty-four patients with regular corneal astigmatism of at least 1.00 D underwent implantation of AcrySof toric intraocular lens, including T3 group 19 eyes, T4 group 18 eyes,...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2015.01.12

    authors： Xiao XW,Hao J,Zhang H,Tian F

    更新日期：2015-02-18 00:00:00

  • Ocular penetration of topically applied 1% tigecycline in a rabbit model.

    abstract：AIM:To evaluate ocular penetration of topically applied 1% tigecycline. METHODS:Forty-two New Zealand White rabbits were divided into 3 groups. A 50 µL drop of 1% tigecycline was administered in group 1. In groups 2 and 3, the drop was administered every 15min for 60min (keratitis protocol). Aqueous humor samples in g...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2017.05.03

    authors： Sakarya Y,Sakarya R,Ozcimen M,Goktas S,Ozcimen S,Alpfidan I,Ivacık IS,Erdogan E,Cetinkaya S,Bukus A

    更新日期：2017-05-18 00:00:00

  • Promotion of axon regeneration and inhibition of astrocyte activation by alpha A-crystallin on crushed optic nerve.

    abstract：AIM:To explore the effects of αA-crystallin in astrocyte gliosis after optic nerve crush (ONC) and the mechanism of α-crystallin in neuroprotection and axon regeneration. METHODS:ONC was established on the Sprague-Dawley rat model and αA-crystallin (10(-4) g/L, 4 µL) was intravitreously injected into the rat model. Fl...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2016.07.04

    authors： Shao WY,Liu X,Gu XL,Ying X,Wu N,Xu HW,Wang Y

    更新日期：2016-07-18 00:00:00

  • Comparison of intravitreal bevacizumab with intravitreal triamcinolone acetonide for treatment of cystoid macular edema secondary to retinal vein occlusion: a Meta-analysis.

    abstract：AIM:To compare the effects of intravitreal injection of bevacizumab (IVB) with intravitreal triamcinolone acetonide (IVTA) on the treatment of cystoid macular edema (CME) secondary to retinal vein occlusion (RVO). METHODS:A literature search was conducted using PubMed, the Cochrane Central Register of Controlled Trial...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2015.06.29

    authors： Sun Y,Qu Y

    更新日期：2015-12-18 00:00:00

  • Non-simulator-based techniques in teaching direct ophthalmoscopy for medical students: a systematic review.

    abstract：:Non-simulator-based examination methods of the fundal examination have shown to be cost-effective. We reviewed different non-simulator-based direct fundoscopy examination methods used in undergraduate curricula and their outcomes. PubMed (MEDLINE) and Cochrane Database of Systematic Reviews were searched using standar...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章,评审

    doi：10.18240/ijo.2020.04.20

    authors： Samaranayake UMJE,Mathangasinghe Y,Samaranayake UMNP,Wijayatunga M

    更新日期：2020-04-18 00:00:00

  • The Beijing Desheng Diabetic Eye Study: rationale, design, methodology and baseline data.

    abstract：AIM:To present the rationale, design, methodology, and the baseline data of the Beijing Desheng Diabetic Eye Study (BDDES), and to determine the prevalence of diabetic retinopathy (DR) and possible risk factors in patients with type 2 diabetes mellitus (T2DM) in an urban community of Beijing, China. METHODS:Community-...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2018.01.19

    authors： Li YY,Yang XF,Gu H,Liu XP,Snellingen T,Liu NP

    更新日期：2018-01-18 00:00:00

  • Retinoblastoma: concerning its initiation and treatment.

    abstract：:Retinoblastoma (RB) is the most common intraocular cancer of infancy and childhood. This cancer is initiated by mutation on RB1, the tumor suppressor gene that is responsible for the regulation of both cell cycle and gnome stability in retinal cells. Patients with a constitutional mutation on RB1 can be inherited. RB ...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2013.03.26

    authors： Luo C,Deng YP

    更新日期：2013-06-18 00:00:00

  • Proteomic analysis of energy metabolism and signal transduction in irradiated melanoma cells.

    abstract：AIM:To analyze proteomic and signal transduction alterations in irradiated melanoma cells. METHODS:We combined stable isotope labeling with amino acids in cell culture (SILAC) with highly sensitive shotgun tandem mass spectrometry (MS) to create an efficient approach for protein quantification. Protein-protein interac...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2013.03.06

    authors： Yan LB,Shi K,Bing ZT,Sun YL,Shen Y

    更新日期：2013-06-18 00:00:00

  • Histopathological changes in retinas and F-ERG features of streptozotocin-induced diabetic rats treated with ozone.

    abstract：AIM:To study the histopathological changes in the retina and flash electroretinogram (F-ERG) features of ozone-treated streptozotocin (STZ)-induced diabetic rats. METHODS:Seventy male Sprague Dawley rats were grouped as follows: blank group (GB, n=10), model control group (GM, n=18), ozone group (GO3, n=19), and oxyge...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2016.06.04

    authors： Xie TY,Li Q,Chen XY

    更新日期：2016-06-18 00:00:00

  • Retraction Notice.

    abstract：:[This retracts the article DOI: 10.3980/j.issn.2222-3959.2015.01.27.]. ...

    journal_title：International journal of ophthalmology

    pub_type： 撤回出版物

    doi：

    authors：

    更新日期：2017-07-18 00:00:00

  • Anatomical characterization of central, apical and minimal corneal thickness.

    abstract：AIM:To anatomically locate the points of minimum corneal thickness and central corneal thickness (pupil center) in relation to the corneal apex. METHODS:Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex (AT), minimum corneal thickness (MT) and corneal thickness at the pupil ce...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2014.04.15

    authors： Saenz-Frances F,Bermúdez-Vallecilla MC,Borrego-Sanz L,Jañez L,Martinez-de-la-Casa JM,Morales-Fernandez L,Santos-Bueso E,Garcia-Sanchez J,Garcia-Feijoo J

    更新日期：2014-08-18 00:00:00

  • Construction of a full-thickness human corneal substitute from anterior acellular porcine corneal matrix and human corneal cells.

    abstract：AIM:To construct functional human full-thickness corneal replacements. METHODS:Acellular porcine corneal matrix (APCM) was developed from porcine cornea by decellulariztion. The biomechanical properties of anterior-APCM (AAPCM) and posterior-APCM (PAPCM) were checked using uniaxial tensile testing. Human corneal cells...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2019.03.01

    authors： Zhang K,Ren XX,Li P,Pang KP,Wang H

    更新日期：2019-03-18 00:00:00

  • Newly onset indirect traumatic optic neuropathy-surgical treatment first versus steroid treatment first.

    abstract：AIM:To investigate the efficacy and safety of the treatment of endoscopic trans-ethmosphenoid optic canal decompression (ETOCD) with combination of steroid in patients with newly onset indirect traumatic optic neuropathy (ITON) and compare the outcome between immediate ETOCD treatment and ETOCD with preoperative steroi...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2020.01.18

    authors： Yu B,Ma YJ,Tu YH,Wu WC

    更新日期：2020-01-18 00:00:00

  • Clinical evaluation of two multifocal intraocular lens implantation patterns.

    abstract：AIM:To evaluate the visual outcomes and patient satisfaction of two multifocal intraocular lens implantation patterns, with the decision between the two patterns being guided by the patients' choice of visual zones that best suited their lifestyle, or lifestyle zones. METHODS:This is a prospective non-randomized compa...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2012.01.16

    authors： Lin HT,Chen WR,Ding ZF,Chen W,Wu CR

    更新日期：2012-01-01 00:00:00

  • Effect of four different intraocular lenses on posterior capsule opacification.

    abstract：AIM:To evaluate the impact of 4 different intraocular lenses (IOLs) on posterior capsule opacification (PCO) by comparing the neodymium: yttrium-aluminum-garnet (Nd:YAG) laser capsulotomy rates. METHODS:This retrospective study included 4970 eyes of 4013 cataract patients who underwent phacoemulsification and IOL impl...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2015.01.22

    authors： Duman R,Karel F,Özyol P,Ateş C

    更新日期：2015-02-18 00:00:00

  • Comparison of posterior capsule opacification at 360-degree square edge hydrophilic and sharp edge hydrophobic acrylic intraocular lens in diabetic patients.

    abstract：AIM:To compare posterior capsule opacification (PCO) degree and visual functions after phacoemulsification in eyes implanted with 360-degree square edge hydrophilic acrylic intraocular lens (IOL) (570C C-flex, Rayner) and sharp edge hydrophobic acrylic IOL (Sensar AR40e, AMO) in diabetic patients. METHODS:Sixty diabet...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2015.04.15

    authors： Bai L,Zhang J,Chen L,Ma T,Liang HC

    更新日期：2015-08-18 00:00:00

  • Orbital metastases in Italy.

    abstract：AIM:To describe a series of Italian patients with orbital metastasis focusing on the outcomes in relation to the different primary site of malignancy. METHODS:Retrospective chart review of 93 patients with orbital metastasis collected in a tertiary referral centre in a period of 38y and review of literature. RESULTS:...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2015.05.30

    authors： Magliozzi P,Strianese D,Bonavolontà P,Ferrara M,Ruggiero P,Carandente R,Bonavolontà G,Tranfa F

    更新日期：2015-10-18 00:00:00

  • A 4-year retrospective study of add-on therapy to the fixed combination of dorzolamide/timolol for the treatment of POAG.

    abstract：AIM:To evaluate the long-term response to the fixed combination of dorzolamide/timolol in patients with primary open angle glaucoma (POAG) and the addition of other intraocular pressure (IOP) lowering medications such as prostaglandin analogs and brimonidine. METHODS:A retrospective, non-randomized, and descriptive cl...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2014.02.25

    authors： Hartleben-Matkin C,Prada D,Mancilla-Vences R

    更新日期：2014-04-18 00:00:00

  • Optical coherence tomography angiography of optic disc perfusion in non-arteritic anterior ischemic optic neuropathy.

    abstract：AIM:To compare the optic disc blood flow of non-arteritic ischemic optic neuropathy (NAION) eyes with normal eyes. METHODS:The optic disc blood flow densities of diagnosed non-acute phase NAION eyes (21 eyes, 14 individuals) and normal eyes (19 eyes, 12 individuals) were detected via Optovue optical coherence tomograp...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2017.09.12

    authors： Ling JW,Yin X,Lu QY,Chen YY,Lu PR

    更新日期：2017-09-18 00:00:00

  • Epidemiology, genetics and treatments for myopia.

    abstract：:Myopia is a significant public health problem and its prevalence is increasing over time and genetic factors in disease development are important. The prevalence and incidence of myopia within sampled population often varies with age, country, sex, race, ethnicity, occupation, environment, and other factors. Myopia gr...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2011.06.17

    authors： Yu L,Li ZK,Gao JR,Liu JR,Xu CT

    更新日期：2011-01-01 00:00:00

  • Dedifferentiated Orbital liposarcoma: a case report.

    abstract：AIM:To report the abnormal type of the orbital liposarcoma-dedifferentiated subtype in a patient. METHODS:A case report. RESULTS:A 23 years old Chinese woman with a recurrence of right-sided proptosis was evaluated. Ocular examination revealed proptosis of the right eye with chemosis, hyperemia and limitation of eye ...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2011.04.26

    authors： Zhang JX,Ma JM,Wang NL

    更新日期：2011-01-01 00:00:00

  • Application of sodium hyaluronate to the operation of suturing the corneal perforation.

    abstract：AIM:To evaluate the effect of the application of sodium hyaluronate on the operation of suturing the corneal perforation. METHODS:Sodium hyaluronate was used in the operation of suturing the corneal perforation in 76 patients to form the anterior chamber, protect eye tissues and separate the anterior iris synechia. R...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.3980/j.issn.2222-3959.2010.03.21

    authors： Jiang T,Jiang J,Zhou Y,Zhao GQ,Yang SS,Li H,Shen L

    更新日期：2010-01-01 00:00:00

  • Host immune cellular reactions in corneal neovascularization.

    abstract：:Corneal neovascularization (CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme- and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article aims to discuss immu...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章,评审

    doi：10.18240/ijo.2016.04.25

    authors： Abdelfattah NS,Amgad M,Zayed AA

    更新日期：2016-04-18 00:00:00

  • Inhibition of LY294002 in retinal neovascularization via down-regulation the PI3K/AKT-VEGF pathway in vivo and in vitro.

    abstract：AIM:To investigate the effects of the phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 on retinal neovascularization (RNV) in the oxygen-induced retinopathy (OIR) mouse model and human umbilical vein endothelial cells (HUVECs). METHODS:C57BL/6J mice were randomly divided into normoxia-control, OIR-control and L...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2018.08.06

    authors： Di Y,Chen XL

    更新日期：2018-08-18 00:00:00

  • Oxidative stress affects retinal pigment epithelial cell survival through epidermal growth factor receptor/AKT signaling pathway.

    abstract：AIM:To investigate the cross-talk between oxidative stress and the epidermal growth factor receptor (EGFR)/AKT signaling pathway in retinal pigment epithelial (RPE) cells. METHODS:Human RPE cell lines (ARPE-19 cell) were treated with different doses of epidermal growth factor (EGF) and hydrogen peroxide (H2O2). Cell v...

    journal_title：International journal of ophthalmology

    pub_type： 杂志文章

    doi：10.18240/ijo.2017.04.02

    authors： Chen XD,Su MY,Chen TT,Hong HY,Han AD,Li WS

    更新日期：2017-04-18 00:00:00