Host immune cellular reactions in corneal neovascularization.

Abstract:

:Corneal neovascularization (CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme- and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article aims to discuss immune cells of particular relevance to CNV, with a focus on macrophages, Th17 cells, dendritic cells and the underlying immunology of common pathologies involving neovascularization of the cornea. Hopefully, a thorough understanding of these topics would propel the efforts to halt the detrimental effects of CNV.

journal_name

Int J Ophthalmol

authors

Abdelfattah NS,Amgad M,Zayed AA

doi

10.18240/ijo.2016.04.25

subject

Has Abstract

pub_date

2016-04-18 00:00:00

pages

625-33

issue

4

eissn

2222-3959

issn

2227-4898

pii

ijo-09-04-625

journal_volume

9

pub_type

杂志文章,评审
  • Incidence of cystoid macular edema after Descemet's stripping automated endothelial keratoplasty.

    abstract:AIM:To determine the incidence of cystoid macular edema (CME) after Descemet's stripping automated endothelial keratoplasty (DSAEK). METHODS:This study included all consecutive patients operated in a Spanish tertiary reference hospital over a period of four years. A total of 55 eyes from 47 patients matched the select...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.07.10

    authors: Pedemonte-Sarrias E,Salvador Playà T,Sassot Cladera I,Gris O,Ribas Martínez J,García-Arumí J,Giménez N

    更新日期:2017-07-18 00:00:00

  • Corneal alteration and pathogenesis in diabetes mellitus.

    abstract::The incidence of diabetes mellitus (DM) and its complications have increased considerably worldwide. Diabetic keratopathy is the major complication of the cornea characterized by delayed corneal wound healing, decreasing corneal epithelial sensitivity, and recurrent corneal ulcers. There is accumulating evidence that ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.18240/ijo.2019.12.17

    authors: Zhao H,He Y,Ren YR,Chen BH

    更新日期:2019-12-18 00:00:00

  • Diagnosis of lacrimal punctum lesions using optical coherence tomography: a preliminary study.

    abstract:AIM:To study the imaging characteristics of lacrimal punctum lesion with optical coherence tomography (OCT), and provide imaging basis for the diagnosis and treatment of lacrimal punctum diseases. METHODS:A total of 25 patients (28 eyes) with epiphora and lacrimal puncta lesions were enrolled. Lacrimal puncta lesions ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2020.06.07

    authors: Tao H,Wang YS,Wang F,Wang HB,Dong WL,Bai F,Wang P,Zhou XB,Wang LH,Liu C

    更新日期:2020-06-18 00:00:00

  • Aerocyst urethral catheter insertion compared to expansion sponges application in external dacryocystorhinostomy.

    abstract:AIM:To evaluate the clinical effect and complications of two different filling materials (aerocyst urethral catheter and expansion sponges) applying in external dacryocystorhinostomy (EXT-DCR) and compare their advantages and disadvantages. METHODS:A retrospective study was made in the period from April, 1 2000 to Apr...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2011.05.08

    authors: Shao Y,Yu Y,Pei CG,Zhou Q,Dong WJ,Qu Y,Yang L,Gao GP

    更新日期:2011-01-01 00:00:00

  • Comparison of intravitreal bevacizumab with intravitreal triamcinolone acetonide for treatment of cystoid macular edema secondary to retinal vein occlusion: a Meta-analysis.

    abstract:AIM:To compare the effects of intravitreal injection of bevacizumab (IVB) with intravitreal triamcinolone acetonide (IVTA) on the treatment of cystoid macular edema (CME) secondary to retinal vein occlusion (RVO). METHODS:A literature search was conducted using PubMed, the Cochrane Central Register of Controlled Trial...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2015.06.29

    authors: Sun Y,Qu Y

    更新日期:2015-12-18 00:00:00

  • Clinical features and surgical treatment of double elevator palsy in young children.

    abstract:AIM:To describe the clinical features of congenital double elevator palsy (CDEP) and to evaluate various surgical outcomes between the standard Knapp and augmented Knapp procedures, based on improvements in primary eye position and ocular motility. METHODS:Twenty-two patients with CDEP at Shanghai Children's Hospital ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2018.08.16

    authors: Luo WT,Qiao T,Ye HY,Li SH,Chen QL

    更新日期:2018-08-18 00:00:00

  • Post-operative strabismus control and motor alignment for basic intermittent exotropia.

    abstract:AIM:To assess strabismus control and motor ocular alignment for basic exotropia surgery at 5y follow-up. METHODS:The medical records of 80 consecutive patients aged less than 17 years of age, who underwent surgery for basic exotropia by a single surgeon between years 2000 to 2009 and completed a minimum of 5y follow-u...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2016.07.13

    authors: Chew FL,Gesite-de Leon BU,Quah BL

    更新日期:2016-07-18 00:00:00

  • Correlation between optical coherence tomography, multifocal electroretinogram findings and visual acuity in diabetic macular edema.

    abstract:AIM:To analyze the correlation between macular morphology and function in eyes with diabetic macular edema (DME). METHODS:Fifty-five eyes with different visual acuity (VA) of 32 patients who suffered from DME were analyzed using multifocal electroretinography (mfERG) and optical coherence tomography (OCT). The paramet...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2020.10.13

    authors: Xia HH,Chen JL,Chen HY,Lin HJ

    更新日期:2020-10-18 00:00:00

  • Pentacam changes in primary angle-closure glaucoma after different lines of treatment.

    abstract:AIM:To assess the changes in the anterior chamber parameters using Pentacam following four different lines of treatment of primary angle-closure glaucoma (PACG). METHODS:A retrospective comparative study included 126 patients (126 eye) presented within 24-48h after acute angle-closure glaucoma (AACG). Patients were di...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2020.04.10

    authors: Mokbel TH,Elhesy AE,Alnagdy A,Elashri MF,Eissa AM,Gaafar WM,Hagras SM

    更新日期:2020-04-18 00:00:00

  • Nanotechnology in retinal drug delivery.

    abstract::Retinal diseases, including age-related macular degeneration (AMD) and diabetic retinopathy (DR) are the leading causes of blindness in adults over the age of 50 years in the US. While most of those conditions do not have a cure, currently available treatment options attempt to prevent further vision loss. For many op...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.18240/ijo.2018.06.23

    authors: Jiang S,Franco YL,Zhou Y,Chen J

    更新日期:2018-06-18 00:00:00

  • Effect of lens constants optimization on the accuracy of intraocular lens power calculation formulas for highly myopic eyes.

    abstract:AIM:To evaluate the effect of different lens constant optimization methods on the accuracy of intraocular lens (IOL) power calculation formulas for highly myopic eyes. METHODS:This study comprised 108 eyes of 94 consecutive patients with axial length (AL) over 26 mm undergoing phacoemulsification and implantation of a...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2019.06.10

    authors: Zhang JQ,Zou XY,Zheng DY,Chen WR,Sun A,Luo LX

    更新日期:2019-06-18 00:00:00

  • Association of macular pigment optical density with early stage of non-proliferative diabetic retinopathy in Chinese patients with type 2 diabetes mellitus.

    abstract:AIM:To detect the association between macular pigment optical density (MPOD), which reflects the antioxidant ability of retina, and diabetic retinopathy (DR) and to investigate the correlated factors of MPOD. METHODS:Totally 435 subjects of urban Chinese were recruited to the study and divided into 3 groups: non-diabe...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2016.10.11

    authors: She CY,Gu H,Xu J,Yang XF,Ren XT,Liu NP

    更新日期:2016-10-18 00:00:00

  • Long-term rotational stability and visual outcomes of a single-piece hydrophilic acrylic toric IOL: a 1.5-year follow-up.

    abstract:AIM:To evaluate the rotational stability and visual outcomes of a single-piece hydrophilic acrylic toric intraocular lenses (IOL) over a 1.5-year follow-up period. Data from the 6-month follow-up study have been previously reported. METHODS:Forty eyes of 26 cataract patients (mean age: 72.8±7.9y) with pre-existing cor...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.04.12

    authors: Gyöngyössy B,Jirak P,Schönherr U

    更新日期:2017-04-18 00:00:00

  • B-scan ultrasound and cytology of the vitreous in primary central nervous system lymphoma with vitreoretinal involvement.

    abstract:AIM:To evaluate the diagnostic value of B-scan ultrasound and explore the cytological characteristics of patients with vitreoretinal lymphoma (VRL) and primary central nervous system lymphoma (PCNSL). METHODS:The clinical data and pathologic specimens from patients with VRL diagnosed at the North Huashan Hospital from...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2019.06.20

    authors: Lai J,Chen K,Shi HM,Zhuang L,Zhou X,Xiao JJ,Li Y,Chen BB,Wang QP

    更新日期:2019-06-18 00:00:00

  • Diagnostic performance of OCT and OCTA in less than 60-year-old patients with early POAG: a cross-sectional study.

    abstract:AIM:To observe and characterize imaging features of macular and optic disc areas in less than 60-year-old patients with early primary open angle glaucoma (POAG) by optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA), and to evaluate the diagnostic value of OCT and OCTA. METHODS:Total...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2020.12.11

    authors: Li YJ,Liu WS,Bai ZC,Cao RX,Ren HH

    更新日期:2020-12-18 00:00:00

  • Dedifferentiated Orbital liposarcoma: a case report.

    abstract:AIM:To report the abnormal type of the orbital liposarcoma-dedifferentiated subtype in a patient. METHODS:A case report. RESULTS:A 23 years old Chinese woman with a recurrence of right-sided proptosis was evaluated. Ocular examination revealed proptosis of the right eye with chemosis, hyperemia and limitation of eye ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2011.04.26

    authors: Zhang JX,Ma JM,Wang NL

    更新日期:2011-01-01 00:00:00

  • Correlation analysis and multiple regression formulas of refractive errors and ocular components.

    abstract::The multiple regression formulas and correlation of ocular components with refractive errors are presented by Gaussian optics. The refractive error changing rate for the cornea and lens power, the axial length, anterior chamber depth (ACD) and vitreous chamber depth (VCD) are calculated, including nonlinear terms for ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2019.05.26

    authors: Chang CK,Lin JT,Zhang Y

    更新日期:2019-05-18 00:00:00

  • Comparison of clinical outcomes of deep anterior lamellar keratoplasty and excimer laser assisted anterior lamellar keratoplasty in keratoconus.

    abstract:AIM:To compare and evaluate the clinical outcomes of deep anterior lamellar keratoplasty (DALK) and excimer laser assisted anterior lamellar keratoplasty (ELLK) in eyes with keratoconus. METHODS:In this study, 57 eyes of 56 patients operated between 2013 to 2017 were included. Thirty-one eyes underwent big-bubble DALK...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2019.04.09

    authors: Ceylanoglu KS,Aydin B,Ozmen MC

    更新日期:2019-04-18 00:00:00

  • A 4-year retrospective study of add-on therapy to the fixed combination of dorzolamide/timolol for the treatment of POAG.

    abstract:AIM:To evaluate the long-term response to the fixed combination of dorzolamide/timolol in patients with primary open angle glaucoma (POAG) and the addition of other intraocular pressure (IOP) lowering medications such as prostaglandin analogs and brimonidine. METHODS:A retrospective, non-randomized, and descriptive cl...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2014.02.25

    authors: Hartleben-Matkin C,Prada D,Mancilla-Vences R

    更新日期:2014-04-18 00:00:00

  • Complement factors C1q, C3 and C5b-9 in the posterior sclera of guinea pigs with negative lens-defocused myopia.

    abstract:AIM:To investigate the expression of complement factors in the posterior scleral fibroblasts of guinea pigs with negative lens-defocused myopia. METHODS:Eighteen guinea pigs were assigned randomly to two groups: the negative lens-defocused group (NLD group, n=9) and the normal control without treatment group (NC group,...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2015.04.06

    authors: Gao TT,Long Q,Yang X

    更新日期:2015-08-18 00:00:00

  • Surgical treatment and visual outcomes of cataract with persistent hyperplastic primary vitreous.

    abstract:AIM:To evaluate the surgical treatment and visual outcomes of eyes with cataract and persistent hyperplastic primary vitreous (PHPV). METHODS:This retrospective study included patients with cataract and PHPV treated with various strategies. Anterior PHPV was treated using phacoemulsification with underwater electric c...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.03.11

    authors: Li L,Fan DB,Zhao YT,Li Y,Cai FF,Zheng GY

    更新日期:2017-03-18 00:00:00

  • Effect of latanoprost/timolol and dorzolamide/tiomolol on intraocular pressure after phacoemulsification surgery.

    abstract:AIM:To evalaute the effect of fixed-combination latanoprost 0.005%/timolol maleate 0.5% and dorzolamide hydrochloride 2%/timolol maleate 0.5% on postoperative intraocular pressure after phacoemulsification cataract surgery. METHODS:This study is a prospective, randomized, double-masked and placebo-controlled. The stud...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2011.02.17

    authors: Erdogan H,Ozec AV,Caner C,Toker MI,Arici MK,Topalkara A

    更新日期:2011-01-01 00:00:00

  • Clinical observations of iridociliary cysts and their changes after implantable collamer lens implantation in myopic patients.

    abstract:AIM:To observe the characteristics of iridociliary cysts in myopic patients and evaluate the influences on the position and safety of implantable collamer lens (ICL) after surgery. METHODS:Totally 270 eyes of 135 patients who underwent ICL surgery for the corrections of myopia were included in this study. Preoperative...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2020.06.17

    authors: Chen Q,Qi MY,Lei XH,Zeng QY

    更新日期:2020-06-18 00:00:00

  • Comparison of lens oxidative damage induced by vitrectomy and/or hyperoxia in rabbits.

    abstract:AIM:To compare of lens oxidative damage induced by vitrectomy and/or hyperoxia in rabbit. METHODS:Sixteen New Zealand rabbits (2.4-2.5 kg) were randomly divided into two groups (Group A, n=12; Group B, n=4). In Group A, the right eyes were treated with vitrectomy and systemic hyperoxia (oxygen concentration: 80%-85%, ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.01.02

    authors: Yan H,Wang D,Ding TB,Zhou HY,Yan WJ,Wang XC

    更新日期:2017-01-18 00:00:00

  • Comparison of corneal measurements in keratoconic eyes using rotating Scheimpflug camera and scanning-slit topography.

    abstract:AIM:To compare the anterior segment measurements obtained by rotating Scheimpflug camera (Pentacam) and Scanning-slit topography (Orbscan IIz) in keratoconic eyes. METHODS:A total of 121 patients, 71 males (58.7%) and 50 females (41.3%) (214 eyes) with the diagnosis of keratoconus (KC) were enrolled in this study. Fol...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2015.02.11

    authors: Naderan M,Shoar S,Naderan M,Kamaleddin MA,Rajabi MT

    更新日期:2015-04-18 00:00:00

  • Orbital metastases in Italy.

    abstract:AIM:To describe a series of Italian patients with orbital metastasis focusing on the outcomes in relation to the different primary site of malignancy. METHODS:Retrospective chart review of 93 patients with orbital metastasis collected in a tertiary referral centre in a period of 38y and review of literature. RESULTS:...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2015.05.30

    authors: Magliozzi P,Strianese D,Bonavolontà P,Ferrara M,Ruggiero P,Carandente R,Bonavolontà G,Tranfa F

    更新日期:2015-10-18 00:00:00

  • Clinical results of non-Descemet stripping endothelial keratoplasty.

    abstract:AIM:To investigate the impact of non-Descemet stripping endothelial keratoplasty (non-DSEK) on graft rejection rate, and its overall procedural effectiveness in patients. METHODS:Non-DSEK was performed on 65 eyes of 64 patients, and the procedural outcomes, including rejection episodes, failure and dislocation of the ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.02.07

    authors: Zhang T,Li SW,Chen TH,He JL,Kang YW,Lyu FQ,Ning JH,Liu C

    更新日期:2017-02-18 00:00:00

  • Clinical characteristics of asymptomatic Terson syndrome in the patients with aneurysmal subarachnoid hemorrhage.

    abstract:AIM:To investigate clinical characteristics of asymptomatic Terson syndrome and its clinical impact in patients with aneurysmal subarachnoid hemorrhage (SAH). METHODS:This retrospective, interventional study included 31 patients with aneurysmal SAH, and the medical records were reviewed. In addition to baseline charac...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2020.02.14

    authors: Kang HM,Cho JM,Kim SY,Choi JH

    更新日期:2020-02-18 00:00:00

  • Inhibition effect of curcumin on UVB-induced secretion of pro-inflammatory cytokines from corneal limbus epithelial cells.

    abstract:AIM:To study the effects of curcumin on the secretion of interleukin (IL)-6 and IL-8 by corneal limbus epithelial cells. METHODS:Human corneal limbus epithelial cells were isolated and cultured from donor eyes and irradiated by UVB at different dosages with or without curcumin. MTT test was used for studying the effec...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.06.01

    authors: Chao SC,Hu DN,Roberts J,Shen X,Lee CY,Nien CW,Lin HY

    更新日期:2017-06-18 00:00:00

  • Comparation of effectiveness of silicone hydrogel contact lens and hydrogel contact lens in patients after LASEK.

    abstract:AIM:To conduct a comparative study of effectiveness of silicone hydrogel contact lens and hydrogel contact lens, which are used in patients after laser-assisted subepithelial keratomileusis (LASEK). METHODS:Sixty-three patients (121 eyes) with a spherical equivalent ≤-5.0 D were chosen after undergoing LASEK in 2012 a...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2015.06.09

    authors: Xie WJ,Zeng J,Cui Y,Li J,Li ZM,Liao WX,Yang XH

    更新日期:2015-12-18 00:00:00