Pentacam changes in primary angle-closure glaucoma after different lines of treatment.

Abstract:

AIM:To assess the changes in the anterior chamber parameters using Pentacam following four different lines of treatment of primary angle-closure glaucoma (PACG). METHODS:A retrospective comparative study included 126 patients (126 eye) presented within 24-48h after acute angle-closure glaucoma (AACG). Patients were divided into 2 groups: group A (68 eyes) with controlled intraocular pressure (IOP) ≤21 mm Hg, which included subgroup A1 (34 eyes) with clear lens underwent Nd:YAG laser peripheral iridotomy (LPI) and subgroup A2 (34 eyes) with cataract underwent standard phacoemulsification; and group B (58 eyes) with uncontrolled IOP, which included subgroup B1 (30 eyes) with clear lens underwent trabeculectomy and subgroup B2 (28 eyes) with cataract underwent combined phacoemulsification and trabeculectomy. Patients were followed up for at least 3mo. Primary outcomes were Pentacam anterior segment measurements [anterior chamber angle (ACA) and depth (ACD)]. Secondary outcomes were changes in IOP, visual acuity (VA) and recorded complications. RESULTS:At the 3rd month, there was significant increase in the ACA values in all studied groups compared to preoperative values (P<0.001). The highest percent of increase in ACA was recorded in phacotrabeculectomy group B2 (128.40%). There was significant increase in ACD values at 3rd month compared with baseline values (P<0.001) for groups A1, A2, and B2; without change in B1 trabeculectomy group. The maximum deepening of ACD was noticed in group B2 with 94.27% increase. Significant decrease in postoperative IOP in groups A2, B1 and B2 (P<0.001, P=0.014, and P<0.001 respectively). In group A1 there was significant increase in 3rd month postoperative IOP from baseline values (P<0.001). The maximum decrease in IOP was noticed in group B2 with 59.54% decrease. VA improvement in 3rd month postoperative was recorded in all studied groups, maximum VA improvement was observed in group B2 up to 0.2 logMAR. CONCLUSION:Pentacam can be a helpful tool in studying and comparing the effect of the different lines of management of PACG on the anterior chamber measures. Phacotrabeculectomy was proved to be an effective line for managing PACG with resultant significant increase in the anterior chamber parameters, IOP reduction as well as maximum VA improvement. LPI has only temporary effect on IOP with significant changes in ACA and ACD. Phacoemuslification alone can be an option in treating PACG. Trabeculectomy resulted in temporary increase in the anterior chamber parameter which subsequently returned to baseline values.

journal_name

Int J Ophthalmol

authors

Mokbel TH,Elhesy AE,Alnagdy A,Elashri MF,Eissa AM,Gaafar WM,Hagras SM

doi

10.18240/ijo.2020.04.10

subject

Has Abstract

pub_date

2020-04-18 00:00:00

pages

591-598

issue

4

eissn

2222-3959

issn

2227-4898

pii

ijo-13-04-591

journal_volume

13

pub_type

杂志文章
  • Pterygial body epithelium domination of pterygial proliferation with TCF4 as a potential key factor.

    abstract:AIM:To characterize the proliferative capacity of pterygial epithelium in different regions (head, neck and body) of pterygium and explore the function of transcription factor 4 (TCF4) in pterygium proliferation. METHODS:Thirty pterygium tissues and 10 normal conjunctival tissues were obtained from Zhongshan Ophthalmi...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2018.09.07

    authors: Nie C,Zhang XC,Xu SY,Quan YD,Tang ZX,Lu R

    更新日期:2018-09-18 00:00:00

  • The role of intravitreal ranubizumab in the treatment of familial exudative vitreoretinopathy of stage 2 or greater.

    abstract:AIM:To evaluate the role of intravitreal ranubizumab (IVR) in the treatment of familial exudative vitreoretinopathy (FEVR) of stage 2 or greater either as primary or an ajunct to conventional treatments. METHODS:Retrospective, non-controlled clinical study. Thirty patients (37 eyes) diagnosed with FEVR were enrolled. ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2018.06.13

    authors: Lu YZ,Deng GD,Liu JH,Yan H

    更新日期:2018-06-18 00:00:00

  • Age factor affects reading acuity and reading speed in attaining text information.

    abstract:AIM:To investigate the effect of age on reading acuity and reading speed in attaining text information in healthy eyes. METHODS:Reading acuity, critical print size, reading speed and maximum reading speed were measured in groups of 40 children (8 to 12 years old), 40 teenagers (13 to 19 years old), 40 young adults (20...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2019.07.19

    authors: Chen AH,Khalid NM,Buari NH

    更新日期:2019-07-18 00:00:00

  • Diffractive multifocal intraocular lens implantation in patients with monofocal intraocular lens in the contralateral eye.

    abstract:AIM:To evaluate clinical outcomes of unilateral implantation of a diffractive multifocal intraocular lens (IOL) in patients with contralateral monofocal IOL. METHODS:Twenty-two patients who already had implantation of a monofocal IOL in unilateral eye underwent implantation of a diffractive multifocal IOL in contralat...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2020.05.07

    authors: Kim JY,Lee Y,Won HJ,Jeong H,Park JH,Kim MJ,Tchah H

    更新日期:2020-05-18 00:00:00

  • Effects of exogenous recombinant human bone morphogenic protein-7 on the corneal epithelial mesenchymal transition and fibrosis.

    abstract:AIM:To evaluate the effect of exogenous recombinant human bone morphogenic protein-7 (rhBMP-7) on transforming growth factor-β (TGF-β)-induced epithelial mesenchymal cell transition (EMT) and assessed its antifibrotic effect via topical application. METHODS:The cytotoxic effect of rhBMP-7 was evaluated and the EMT of ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.03.01

    authors: Chung JK,Park SA,Hwang HS,Kim KS,Cho YJ,You YS,Kim YS,Jang JW,Lee SJ

    更新日期:2017-03-18 00:00:00

  • Long-term rotational stability and visual outcomes of a single-piece hydrophilic acrylic toric IOL: a 1.5-year follow-up.

    abstract:AIM:To evaluate the rotational stability and visual outcomes of a single-piece hydrophilic acrylic toric intraocular lenses (IOL) over a 1.5-year follow-up period. Data from the 6-month follow-up study have been previously reported. METHODS:Forty eyes of 26 cataract patients (mean age: 72.8±7.9y) with pre-existing cor...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.04.12

    authors: Gyöngyössy B,Jirak P,Schönherr U

    更新日期:2017-04-18 00:00:00

  • Clinical outcomes with large macular holes using the tiled transplantation internal limiting membrane pedicle flap technique.

    abstract:AIM:To report the surgical technique and efficacy of the tiled transplantation internal limiting membrane (ILM) pedicle flap technique after vitrectomy for 33 patients with large macular hole (MH). METHODS:This study was a prospective noncontrolled interventional study. All patients were treated by vitrectomy, the til...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2019.02.10

    authors: Wang LP,Sun WT,Lei CL,Deng J

    更新日期:2019-02-18 00:00:00

  • Comparison of the femtosecond laser and mechanical microkeratome for flap cutting in LASIK.

    abstract:AIM:To compare refractive results, higher-order aberrations (HOAs), contrast sensitivity and dry eye after laser in situ keratomileusis (LASIK) performed with a femtosecond laser versus a mechanical microkeratome for myopia and astigmatism. METHODS:In this prospective, non-randomized study, 120 eyes with myopia receiv...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2015.04.25

    authors: Xia LK,Yu J,Chai GR,Wang D,Li Y

    更新日期:2015-08-18 00:00:00

  • Corneal alteration and pathogenesis in diabetes mellitus.

    abstract::The incidence of diabetes mellitus (DM) and its complications have increased considerably worldwide. Diabetic keratopathy is the major complication of the cornea characterized by delayed corneal wound healing, decreasing corneal epithelial sensitivity, and recurrent corneal ulcers. There is accumulating evidence that ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.18240/ijo.2019.12.17

    authors: Zhao H,He Y,Ren YR,Chen BH

    更新日期:2019-12-18 00:00:00

  • Comparative analysis of the efficacy of astigmatic correction after wavefront-guided and wavefront-optimized LASIK in low and moderate myopic eyes.

    abstract:AIM:To evaluate and compare the efficacy of the astigmatic correction achieved with laser in situ keratomileusis (LASIK) in eyes with myopic astigmatism using wavefront-guided (WFG) and wavefront-optimized (WFO) ablation profiles. METHODS:Prospective study included 221 eyes undergoing LASIK: 99 and 122 eyes with low a...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.02.17

    authors: Khalifa MA,Alsahn MF,Shaheen MS,Pinero DP

    更新日期:2017-02-18 00:00:00

  • Ocular bacterial infections at a tertiary eye center in China: a 5-year review of pathogen distribution and antibiotic sensitivity.

    abstract:AIM:To provide statistical evidence for the use of antibiotics in ophthalmology by assessing the distribution and antibiotic sensitivity of bacterial isolates from ocular specimens with suspected microbial infections. METHODS:This study applied a retrospective analysis of 3690 bacterial isolates from ocular specimens,...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2020.01.08

    authors: Gao W,Xia T,Chen HB,Pan XJ,Huang YS,Wang X,Dong YL,Xie LX

    更新日期:2020-01-18 00:00:00

  • Meta-analysis of best corrected visual acuity after treatment for myopic choroidal neovascularisation.

    abstract:AIM:To compare the best corrected visual acuity (BCVA) between Verteporfin with photodynamic therapy (PDT) and intravitreal anti-vascular endothelial growth factor (anti-VEGF) in patients with myopic choroidal neovascularization (CNV). METHOD:Published literature from Medline, Premedline, Embase and the Cochrane Libra...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2014.04.25

    authors: Zhou L,Xing YQ,Li T,Li Y,Song XS,Li JZ

    更新日期:2014-08-18 00:00:00

  • Objective evaluation of the changes in the crystalline lens during accommodation in young and presbyopic populations using Pentacam HR system.

    abstract:AIM:To quantify the changes in the lens profile with accommodation in different age groups. METHODS:The Pentacam HR system was used to obtain the images of the anterior eye segment from 23 young and 15 presbyopic emmetropic subjects in unaccommodated (with an accommodation stimulus of 0.0D) and accommodated (with an a...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2011.06.07

    authors: Ni Y,Liu XL,Wu MX,Lin Y,Sun YY,He C,Liu YZ

    更新日期:2011-01-01 00:00:00

  • Trocar opening: silicone oil removal with phacoemulsification and intraocular lens implantation.

    abstract:AIM:To evaluate the efficacy and safety of a modified technique [trocar opening (TO)] for silicone oil removal (SOR) in combination with phacoemulsification and intraocular lens (IOL) implantation. METHODS:A total of 60 eyes of 60 patients with cataract and silicone oil-filled eyes were enrolled in this study. The pat...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2019.11.09

    authors: Zhang X,Pan YJ,Song ZY

    更新日期:2019-11-18 00:00:00

  • Posterior vitreous detachment rate following intravitreal dexamethasone injection.

    abstract:AIM:To determine whether intravitreal dexamethasone (DEX) implant induces posterior vitreous detachment or not. METHODS:We retrospectively reviewed 810 eyes of 405 patients who underwent intravitreal DEX implantation due to macular edema caused by diabetic and retinal venous occlusion in our clinic. The eyes having no...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2019.08.10

    authors: Alpay A

    更新日期:2019-08-18 00:00:00

  • Effect of latanoprost/timolol and dorzolamide/tiomolol on intraocular pressure after phacoemulsification surgery.

    abstract:AIM:To evalaute the effect of fixed-combination latanoprost 0.005%/timolol maleate 0.5% and dorzolamide hydrochloride 2%/timolol maleate 0.5% on postoperative intraocular pressure after phacoemulsification cataract surgery. METHODS:This study is a prospective, randomized, double-masked and placebo-controlled. The stud...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2011.02.17

    authors: Erdogan H,Ozec AV,Caner C,Toker MI,Arici MK,Topalkara A

    更新日期:2011-01-01 00:00:00

  • Ultrastructural pathology of corneal neovascularization after photodynamic therapy in rabbits.

    abstract:AIM:To investigate the ultrastructural pathogenesis of photodynamic therapy (PDT) for the experimental corneal neovascularization (CNV) by Hematoporphyrin Derivate (HPD) as photosensitizer and Argon laser as light source. METHODS:Experimental CNV models were induced in 7 white rabbits using alkali burn. Six weeks afte...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2010.04.07

    authors: Chen H,Zhang MC,Wang Z,Zhang Y

    更新日期:2010-01-01 00:00:00

  • Keratinocyte growth factor-2 and autologous serum potentiate the regenerative effect of mesenchymal stem cells in cornea damage in rats.

    abstract:AIM:To investigate the healing process after severe corneal epithelial damage in rats treated with mesenchymal stem cells (MSCs) cultured with or without keratinocyte growth factor (KGF-2) and autologous serum (AS) on amniotic membrane (AM). Many patients are blind and devastated by severe ocular surface diseases due t...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2014.02.05

    authors: Pınarlı FA,Okten G,Beden U,Fışgın T,Kefeli M,Kara N,Duru F,Tomak L

    更新日期:2014-04-18 00:00:00

  • Clinical results of non-Descemet stripping endothelial keratoplasty.

    abstract:AIM:To investigate the impact of non-Descemet stripping endothelial keratoplasty (non-DSEK) on graft rejection rate, and its overall procedural effectiveness in patients. METHODS:Non-DSEK was performed on 65 eyes of 64 patients, and the procedural outcomes, including rejection episodes, failure and dislocation of the ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.02.07

    authors: Zhang T,Li SW,Chen TH,He JL,Kang YW,Lyu FQ,Ning JH,Liu C

    更新日期:2017-02-18 00:00:00

  • Oxidative stress affects retinal pigment epithelial cell survival through epidermal growth factor receptor/AKT signaling pathway.

    abstract:AIM:To investigate the cross-talk between oxidative stress and the epidermal growth factor receptor (EGFR)/AKT signaling pathway in retinal pigment epithelial (RPE) cells. METHODS:Human RPE cell lines (ARPE-19 cell) were treated with different doses of epidermal growth factor (EGF) and hydrogen peroxide (H2O2). Cell v...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.04.02

    authors: Chen XD,Su MY,Chen TT,Hong HY,Han AD,Li WS

    更新日期:2017-04-18 00:00:00

  • Repeatability of in-vitro optical quality measurements of intraocular lenses with a deflectometry technique effect of the toricity.

    abstract:AIM:To evaluate the repeatability of an optical device for measuring the Zernike coefficients of toric intraocular lenses (IOLs) and assess whether its toricity has any impact in its repeatability. METHODS:An experienced technician used the NIMO TR1504 to measure the Zernike coefficients 30 times for an aperture of 4....

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2018.07.11

    authors: Ferrer-Blasco T,Domínguez-Vicent A,García-Lázaro S,Díez-Ajenjo MA,Alfonso JF,Esteve-Taboada JJ

    更新日期:2018-07-18 00:00:00

  • Effect of pan-retinal laser photocoagulation on plasma VEGF, endothelin-1 and nitric oxide in PDR.

    abstract:AIM:To study plasma levels of vascular endothelial growth factor (VEGF), endothelin-1(ET-1) and nitric oxide (NO) in patients with proliferative diabetic retinopathy (PDR) before and after pan-retinal photocoagulation (PRP). METHODS:Forty patients (23 females and 17 males, mean age 48.5±12.2 years) with PDR without pr...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2010.01.05

    authors: Mohamed TA,Mohamed Sel-D

    更新日期:2010-01-01 00:00:00

  • Cigarette smoking, body mass index associated with the risks of age-related cataract in male patients in northeast China.

    abstract:AIM:To determine the association between cigarettes smoking, body mass index (BMI) and the risk of age-related cataract (ARC) in middle-aged and elderly men in Northeast China. METHODS:A hospital-based case control study was conducted. Cases (n =362) were men who had surgically treated ARC, 45-85 years old; controls f...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2012.03.13

    authors: Lu ZQ,Sun WH,Yan J,Jiang TX,Zhai SN,Li Y

    更新日期:2012-01-01 00:00:00

  • Prevalence of meibomian gland dysfunction in staffs and faculty members of a Chinese university.

    abstract:AIM:To assess the prevalence of meibomian gland dysfunction (MGD) in staffs and faculty members of Sichuan University, China. METHODS:The records of the annually systemic physical examination of 4404 consecutive staffs and faculty members of Sichuan University were analyzed retrospectively. Ocular symptoms and signs o...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2020.10.23

    authors: Gao JG,Chen J,Tang Y,Chen DN

    更新日期:2020-10-18 00:00:00

  • Characterization of the geometric properties of the sclero-conjunctival structure: a review.

    abstract::To revise the peer-reviewed literature on geometric properties of the scleral-conjunctival structure in order to define their clinical relevance and the potential relationship between their changes and myopia development or progression. A bibliographic search focused on the study of the geometry of conjunctiva and/or ...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.18240/ijo.2020.09.22

    authors: Bataille L,Piñero DP

    更新日期:2020-09-18 00:00:00

  • Neuroprotection of retinal ganglion cells with GDNF-Loaded biodegradable microspheres in experimental glaucoma.

    abstract::Glaucoma is the second leading cause of blindness worldwide, and also the most common optic neuropathy. The ultimate cause of vision loss in glaucoma is thought to be retinal ganglion cell (RGC) death. Neuroprotection of RGC is therefore an important goal of glaucoma therapy. Currently, glaucoma treatment relies on ph...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2010.03.01

    authors: Xiao JH,Zhang MN

    更新日期:2010-01-01 00:00:00

  • Total lower lid reconstruction: clinical outcomes of utilizing three-layer flap and graft in one session.

    abstract:AIM:To report the clinical outcomes of utilizing a three-layer flap and graft in reconstruction of the lower lid in one session. METHODS:Seventeen patients with total or near total lower eyelid defect were included. The defects were reconstructed in three layers. Posterior lamella was reconstructed by using tarsoconju...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2014.03.22

    authors: Rajabi MT,Bazvand F,Hosseini SS,Makateb A,Rajabi MB,Tabatabaie SZ,Abrishami Y

    更新日期:2014-06-18 00:00:00

  • PI3K/AKT/mTOR signaling pathway inhibitors in proliferation of retinal pigment epithelial cells.

    abstract:AIM:To determine whether the PI3K/AKT/mTOR pathway is activated in proliferative vitreoretinopathy (PVR) in homo-sapiens. METHODS:The retina of controls and patients with PVR were collected and their levels of PI3K, phospho-AKT, phospho-mTOR, phospho-p70S6k and phospho-4EBP-1 were determined by Western blot. The cultu...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.3980/j.issn.2222-3959.2012.06.05

    authors: Cai N,Dai SD,Liu NN,Liu LM,Zhao N,Chen L

    更新日期:2012-01-01 00:00:00

  • The role of Dectin-1/Raf-1 signal cascade in innate immune of human corneal epithelial cells against Aspergillus fumigatus infection.

    abstract:AIM:To investigate the expression of the v-raf-1 murine leukemia viral oncogene homolog 1 (Raf-1) and its role in the innate immune response of human corneal epithelial cells (HCECs) infected by Aspergillus fumigatus. METHODS:HCECs were cultured in vitro. They were randomly divided into 4 groups, including control gro...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2016.10.01

    authors: Zhao GQ,Lin J,Hu LT,Yin XN,Wang Q,Xu Q,Li H

    更新日期:2016-10-18 00:00:00

  • Old canalicular laceration repair: a retrospective study of the curative effects and prognostic factors.

    abstract:AIM:To investigate the epidemiology and surgical outcomes of old canalicular laceration and analyze the variables impacting on the prognosis of reparation. METHODS:A retrospective review of all old canalicular laceration repairs from Jan. 1, 2008 to Dec. 30, 2015 was performed. Analyzed data included demographics, mec...

    journal_title:International journal of ophthalmology

    pub_type: 杂志文章

    doi:10.18240/ijo.2017.06.11

    authors: Bai F,Tao H,Zhang Y,Wang P,Han C,Huang YF,Tao Y

    更新日期:2017-06-18 00:00:00