Abstract:
AIM:To analyze the clinical manifestation of Alport syndrome, especially the ocular features. METHODS:The physical, ophthalmologic and audiologic examination results of thirty-two patients with Alport syndrome were analyzed retrospectively. RESULTS:Thirty (93.7%) patients had some family history. All patients had renal disease: eighteen (56.3%) patients with chronic renal failure, four (12.5%) patients with renal insufficiency, and the other ten (31.3%) patients with hematuria. Twenty (62.5%) patients had sensorineural deafness. Thirteen (40.6%) patients had ocular deformity, five (15.7%) patients had typical ocular changes: three patients with anterior lenticonus, and two patients with macular flecks. CONCLUSION:Ocular anomalies are not requisite for the diagnosis of Alport syndrome. But its typical ocular features should be recognized by the ophthalmologists which supports the diagnosis.
journal_name
Int J Ophthalmoljournal_title
International journal of ophthalmologyauthors
Xu JM,Zhang SS,Zhang Q,Zhou YM,Zhu CH,Ge J,Wang Ldoi
10.3980/j.issn.2222-3959.2010.02.13subject
Has Abstractpub_date
2010-01-01 00:00:00pages
149-51issue
2eissn
2222-3959issn
2227-4898pii
ijo-03-02-149journal_volume
3pub_type
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journal_title:International journal of ophthalmology
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pub_type: 撤回出版物
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