Abstract:
:Abstract This study examined the pathogenesis of large pseudocysts adjacent to knee joints in rheumatoid arthritis (RA). The radiological and histopathological features of 17 large subarticular pseudocysts in 12 knee joints of 10 patients were analyzed. Nine of the 10 patients were classified as class 2 according to Steinbrocker's functional class. Eight large pseudocysts were located at the lateral femoral condyle, seven were at the proximal part of the tibia, one was at the medial femoral condyle, and one was at the patella. The large pseudocysts were divided into two groups according to whether they did or did not connect with the joint cavity. Serial radiographs revealed that all large pseudocysts in communication with the joint cavity had enlarged gradually over the past several months. They extended from the subarticular area toward the bone marrow. Histopathological findings confirmed that holes allowing communication were located at a transitional zone between the ligament and the hyaline cartilage, and that rheumatoid granulation tissue invaded the large pseudocyst through these holes. The results of this study indicate that large pseudocysts are formed by the extension of articular inflammation. Moreover, repeated extrinsic mechanical stress due to walking and the aggressive inflammatory nature of rheumatoid arthritis play important roles in the formation of large pseudocysts.
journal_name
Mod Rheumatoljournal_title
Modern rheumatologyauthors
Yoshida M,Ichinohe S,Uzuki M,Yoshida W,Sawai T,Shimamura Tdoi
10.3109/s101650200022subject
Has Abstractpub_date
2002-06-01 00:00:00pages
128-33issue
2eissn
1439-7595issn
1439-7609journal_volume
12pub_type
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journal_title:Modern rheumatology
pub_type: 杂志文章
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journal_title:Modern rheumatology
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-012-0711-0
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pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章
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更新日期:2013-07-01 00:00:00
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pub_type: 杂志文章
doi:10.3109/14397595.2013.879416
更新日期:2014-09-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1007/s10165-011-0487-7
更新日期:2012-02-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650070020
更新日期:2000-09-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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更新日期:2003-09-01 00:00:00
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doi:10.3109/14397595.2015.1060668
更新日期:2016-01-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 临床试验,杂志文章
doi:10.1007/s10165-006-0487-1
更新日期:2006-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1080/14397595.2016.1253813
更新日期:2017-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-05-01 00:00:00
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