Increased incidence of pre-diabetes mellitus at a department of rheumatology: a retrospective study.

Abstract:

:We aimed to retrospectively review the incidence of pre-diabetes mellitus (preDM), one of the factors in metabolic syndrome screening, in patients with rheumatic diseases. We examined the levels of hemoglobin A1c (HbA1c) in a total of 498 patients with rheumatic diseases between April 2007 and March 2008 at the Department of Rheumatology in Nagasaki University Hospital. Of the 498 patients, 409 (82.1%) had HbA1c levels higher than 5.6% (National Glycohemoglobin Standardization Program; NGSP) and were recommended for health guidance with a focus on metabolic syndrome. Serum HbA1c levels higher than 6.0%, a possible indicator of DM, were seen in 227 patients (45.6%). Serum HbA1c levels higher than 6.5%, which constitute a high risk for DM, were found in 115 patients (23.1%). PreDM increased gradually with age. Our results suggest that the incidence of preDM may be higher in patients with rheumatic diseases than in patients with other diseases and that these patients should receive healthcare guidance to prevent metabolic syndrome.

journal_name

Mod Rheumatol

journal_title

Modern rheumatology

authors

Origuchi T,Yamaguchi S,Inoue A,Kazaura Y,Matsuo N,Abiru N,Kawakami A,Eguchi K

doi

10.1007/s10165-011-0433-8

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

495-9

issue

5

eissn

1439-7595

issn

1439-7609

journal_volume

21

pub_type

杂志文章
  • Effects of functional training on pain, leg strength, and balance in women with fibromyalgia.

    abstract:AIM:The aim of this study was to analyze the effect of 18-week functional training (FT) program consisting in two sessions a week of in-water exercise and one of on-land exercise on pain, strength, and balance in women with fibromyalgia. METHODS:A sample consisting of 36 fibromyalgia patients was included in the study...

    journal_title:Modern rheumatology

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/14397595.2015.1040614

    authors: Latorre Román PÁ,Santos E Campos MA,García-Pinillos F

    更新日期:2015-01-01 00:00:00

  • Development of large pseudocysts adjacent to the knee joint in rheumatoid arthritis. Assessment of radiological and histopathological approaches.

    abstract::Abstract  This study examined the pathogenesis of large pseudocysts adjacent to knee joints in rheumatoid arthritis (RA). The radiological and histopathological features of 17 large subarticular pseudocysts in 12 knee joints of 10 patients were analyzed. Nine of the 10 patients were classified as class 2 according to ...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.3109/s101650200022

    authors: Yoshida M,Ichinohe S,Uzuki M,Yoshida W,Sawai T,Shimamura T

    更新日期:2002-06-01 00:00:00

  • Latent overproductive hyperuricemia increases in patients during the intermittent phase of gouty arthritis under long-term antihyperuricemic treatment.

    abstract::Abstract This work was undertaken to determine baseline urate metabolism in patients during the intermittent phase of gouty arthritis in order to decide on the best treatment for hyperuricemia. Parameters affecting serum urate levels, including uric acid clearance and urinary urate excretion, were re-evaluated in 30 p...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.3109/s101650070003

    authors: Tsutani H,Kiriba C,Imamura S,Yoshio N,Nakamura T,Ueda T

    更新日期:2000-12-01 00:00:00

  • Efficacy and safety of reducing duration of infliximab infusion.

    abstract:OBJECTIVE:To evaluate the safety and efficacy of reducing the duration of infliximab infusion for rheumatoid arthritis (RA) treatment. METHODS:The first 6 infliximab infusions were each administered over a 2-h period. If no adverse reaction was observed, infusion times were shortened to 1 h starting with the seventh i...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.3109/14397595.2013.843747

    authors: Fukuyo S,Saito K,Yamaoka K,Sawamukai N,Hirata S,Nawata M,Iwata S,Tanaka Y

    更新日期:2014-03-01 00:00:00

  • Drug eruption due to bosentan in a patient with systemic sclerosis.

    abstract::We present the case of a 60-year-old female patient with systemic sclerosis complicated by pulmonary hypertension. Ten days after the initiation of treatment with bosentan, high fever and skin eruptions were noted. In the previous reports, the frequency of drug-induced skin eruptions has not been well documented. Sinc...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-006-0477-3

    authors: Nagai Y,Yamanaka M,Nishimura S,Nakano A,Hasegawa A,Ishikawa O

    更新日期:2006-01-01 00:00:00

  • Efficacy of adalimumab for a refractory case of relapsing polychondritis with reduction of pro-inflammatory cytokines.

    abstract::A 68-year-old man with a fever of unknown origin was admitted to our hospital. Bilateral auricularis and nasal root inflammation, with auricular perichondritis positive for anti-type II collagen (CII) antibody, led to a diagnosis of relapsing polychondritis (RP). Because the patient was refractory for high-dose glucoc...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-011-0453-4

    authors: Nakamura H,Suzuki T,Nagaoka K,Yamasaki S,Tamai M,Hayashi T,Kawakami A

    更新日期:2011-12-01 00:00:00

  • Multicenter double-blind randomized controlled trial to evaluate the effectiveness and safety of bortezomib as a treatment for refractory systemic lupus erythematosus.

    abstract:OBJECTIVES:The objective of this study is to evaluate the efficacy and safety of bortezomib for treating systemic lupus erythematosus (SLE), in patients whose disease activity could not be controlled. METHODS:Fourteen SLE patients with persistent disease activity were selected, who required prednisolone doses of >10 m...

    journal_title:Modern rheumatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1080/14397595.2018.1432331

    authors: Ishii T,Tanaka Y,Kawakami A,Saito K,Ichinose K,Fujii H,Shirota Y,Shirai T,Fujita Y,Watanabe R,Chiu SW,Yamaguchi T,Harigae H

    更新日期:2018-11-01 00:00:00

  • Lower CH50 as a predictor for intractable or recurrent lupus enteritis: A retrospective observational study.

    abstract:OBJECTIVES:Lupus enteritis (LE) is a rare but well-known gastrointestinal manifestation of systemic lupus erythematosus (SLE). This study was conducted to identify prognostic factors associated with poor responses in patients with LE. METHODS:We consecutively registered patients diagnosed with LE between January 2009 ...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1080/14397595.2020.1812871

    authors: Yoshida Y,Omoto T,Kohno H,Tokunaga T,Kuranobu T,Yukawa K,Watanabe H,Oi K,Sugimoto T,Mokuda S,Nojima T,Hirata S,Sugiyama E

    更新日期:2020-09-07 00:00:00

  • Early diagnosis and treatment for remission of clinically amyopathic dermatomyositis complicated by rapid progress interstitial lung disease: a report of two cases.

    abstract::We report two cases of clinically amyopathic dermatomyositis (CADM) complicated by rapid progress interstitial lung disease (RPILD). The diagnosis of CADM was based on Gottron's papule and RPILD, and the absence of muscle weakness. The female patients were treated with early immunosuppressive therapies including stero...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-012-0637-6

    authors: Horai Y,Isomoto E,Koga T,Okada A,Kawashiri SY,Tamai M,Yamasaki S,Nakamura H,Origuchi T,Hamaguchi Y,Fujimoto M,Kuwana M,Kawakami A

    更新日期:2013-01-01 00:00:00

  • The Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale: reliability and validity.

    abstract::The aim of this study was to investigate the reliability and the validity of the Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia (ACR 2010-J), and its quantification scale, the Fibromyalgia Symptom Scale (FS-J). In this study, we divided patients with chro...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-011-0462-3

    authors: Usui C,Hatta K,Aratani S,Yagishita N,Nishioka K,Kanazawa T,Ito K,Yamano Y,Nakamura H,Nakajima T,Nishioka K

    更新日期:2012-02-01 00:00:00

  • SAA1 gene polymorphisms and the risk of AA amyloidosis in Japanese patients with rheumatoid arthritis.

    abstract::To investigate the precise modality of association between SAA1 gene polymorphisms and the development of AA amyloidosis in patients with rheumatoid arthritis (RA), Japanese patients with RA (n=153), among whom 29 were histologically diagnosed as having amyloidosis, were genotyped for three single nucleotide polymorph...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-006-0500-8

    authors: Ajiro J,Narita I,Sato F,Saga D,Hasegawa H,Kuroda T,Nakano M,Gejyo F

    更新日期:2006-01-01 00:00:00

  • A case of life-threatening refractory polychondritis successfully treated with combined intensive immunosuppressive therapy with methotrexate.

    abstract::Relapsing polychondritis (RP) is a rare disease of unknown etiology causing systematic inflammation and resulting in destruction of cartilaginous tissues. We describe here an 18-year-old Japanese woman who developed severe airway stenosis as the initial symptom with auricular, nasal, and ocular inflammation. The effec...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-006-0548-5

    authors: Yamaoka K,Saito K,Hanami K,Nakayamada S,Nawata M,Iwata S,Azuma T,Tanaka Y

    更新日期:2007-01-01 00:00:00

  • IgG4-related kidney disease and retroperitoneal fibrosis: An update.

    abstract::The most representative kidney lesion of IgG4-related disease (IgG4-RD) is plasma cell-rich tubulointerstitial nephritis (TIN) with distinctive imaging findings including multiple low-density lesions on contrast-enhanced computed tomography. In addition, membranous glomerulonephritis is a representative glomerular les...

    journal_title:Modern rheumatology

    pub_type: 杂志文章,评审

    doi:10.1080/14397595.2018.1554321

    authors: Kawano M,Saeki T,Nakashima H

    更新日期:2019-03-01 00:00:00

  • Scoliosis-related factors in patients with rheumatoid arthritis: A cross-sectional study.

    abstract:OBJECTIVES:This study aimed to identify the prevalence of scoliosis and scoliosis-related factors of rheumatoid arthritis (RA). METHODS:In this study, 411 patients who underwent coronal total spine and lower limb radiography were enrolled. Patients with a Cobb angle ≥10° were diagnosed with scoliosis. Statistical anal...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.3109/14397595.2015.1097016

    authors: Mochizuki T,Yano K,Ikari K,Hiroshima R,Takaoka H,Kawakami K,Koenuma N,Ishibashi M,Shirahata T,Momohara S

    更新日期:2016-01-01 00:00:00

  • Ten years results of bucillamine in the treatment of rheumatoid arthritis.

    abstract::A 10-year cohort study was performed, involving all of the 118 patients treated with bucillamine in our hospital between 1988 and 1990. Evaluation was made on the basis of erythrocyte sedimentation rate, grip strength, joint score, duration of morning stiffness, and Lansbury index consisting of the above four paramete...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-006-0533-z

    authors: Yokota N,Kuga Y,Kanazawa T,Morishita M,Tanida K,Itou K

    更新日期:2007-01-01 00:00:00

  • The epigenetic alteration of synovial cell gene expression in rheumatoid arthritis and the roles of nuclear factor kappaB and Notch signaling pathways.

    abstract::Rheumatoid arthritis (RA) is a complex process of chronic and progressive inflammation associated with activation of numerous signaling molecules and transcription factors and hyperproliferation of synoviocytes of the affected joints, although the greater part of its pathophysiological process is explained by activati...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-004-0372-8

    authors: Okamoto T

    更新日期:2005-01-01 00:00:00

  • Assessment of fatigue in a large series of 1492 Brazilian patients with Spondyloarthritis.

    abstract:BACKGROUND:The aim of the present study was to analyze the score of fatigue in a large cohort of Brazilian patients with SpA, comparing different disease patterns and its association with demographic and disease-specific variables. METHODS:A common protocol of investigation was prospectively applied to 1492 Brazilian ...

    journal_title:Modern rheumatology

    pub_type: 杂志文章,多中心研究

    doi:10.3109/14397595.2014.906049

    authors: Bianchi WA,Elias FR,Carneiro S,Bortoluzzo AB,Gonçalves CR,da Silva JA,Ximenes AC,Bértolo MB,Ribeiro SL,Keiserman M,Skare TL,Menin R,Azevedo VF,Vieira WP,Albuquerque EN,Bonfiglioli R,Campanholo C,Carvalho HM,Costa IP,

    更新日期:2014-11-01 00:00:00

  • Analysis of autoantibodies to cell cycle-associated antigens.

    abstract::Abstract To determine the specificities of autoantibodies targeting cell cycle-associated antigens in rheumatic diseases, we studied 30 sera which were obtained from patients visiting our hospital and which exhibited a variegated speckled pattern in indirect immunofluorescence (IF). The immunoreactivities of the sera ...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.3109/s101650170008

    authors: Fujinaga H,Takeuchi K,Kaneda K,Takasaki Y,Hashimoto H

    更新日期:2001-09-01 00:00:00

  • Clinical and radiological results of non-cement impaction bone-graft method of total hip arthroplasty for rheumatoid arthritis.

    abstract::We performed total hip arthroplasty using the non-cement impaction auto-bone-grafting method with the resected femoral head for acetabular protrusion that is not combined with the destruction of acetabular rim or dysplasia of the hip joint. Ten patients (eight women and two men) with rheumatoid arthritis who showed ac...

    journal_title:Modern rheumatology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10165-007-0571-1

    authors: Mochida Y,Saito I,Akamatsu Y,Taki N,Mitsugi N,Saito T

    更新日期:2007-01-01 00:00:00

  • Real-world practice of obstetricians in respect of assays for antiphospholipid antibodies.

    abstract:OBJECTIVE:The international classification criteria (CC) for definite antiphospholipid syndrome (APS) recommend confirmation of the sustained presence, for at least 12 weeks, of both lupus anticoagulant (LA), as determined by aPTT and RVVT, and anti β2glycoprotein I (β2GPI) or anticardiolipin (aCL) IgG and/or IgM. Howe...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.3109/14397595.2015.1023978

    authors: Sugiura-Ogasawara M,Atsumi T,Yamada H,Kitaori T,Ozaki Y,Katano K,Murashima A

    更新日期:2015-01-01 00:00:00

  • Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA.

    abstract::Bucillamine (Buc) is a disease-modifying antirheumatic drug (DMARD) developed in Japan, which has been used as one of the first-line DMARDs for the treatment of rheumatoid arthritis (RA) in Japan. However, direct comparison of this drug with standard DMARDs including sulfasalazine (SASP) and methotrexate (MTX) has bee...

    journal_title:Modern rheumatology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s10165-006-0527-x

    authors: Iwatani M,Inoue E,Nakamura T,Nakajima A,Hara M,Tomatsu T,Kamatani N,Yamanaka H

    更新日期:2006-01-01 00:00:00

  • A case of Weber-Christian disease associated with myelodysplastic syndrome.

    abstract::We report the case of a 73-year-old man with myelodysplastic syndrome (MDS) who developed Weber-Christian disease (WCD). Bone marrow aspirates showed refractory anemia with abnormal karyotypes such as trisomy 8, trisomy 8 and 14, and trisomy 8, 9, and 14. The patient had intermittent fever associated with multiple ten...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-003-0270-5

    authors: Hojo N,Hasegawa H,Iwamasa K,Hojo S,Fujita S

    更新日期:2004-01-01 00:00:00

  • Prevalence of Helicobacter pylori infection and risk of upper gastrointestinal ulcer in patients with rheumatoid arthritis in Japan.

    abstract::We evaluated the prevalence of Helicobacter pylori infection and the association of H. pylori infection and/or nonsteroidal anti-inflammatory drug (NSAID) use with upper gastrointestinal (UGI) ulcers in a cohort of Japanese patients with rheumatoid arthritis (RA). Using the clinical database of the cohort of RA patien...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-005-0419-5

    authors: Tanaka E,Singh G,Saito A,Syouji A,Yamada T,Urano W,Nakajima A,Taniguchi A,Tomatsu T,Hara M,Saito T,Kamatani N,Yamanaka H

    更新日期:2005-01-01 00:00:00

  • A case of infantile Takayasu arteritis with a p.D382E NOD2 mutation: an unusual phenotype of Blau syndrome/early-onset sarcoidosis?

    abstract::Blau syndrome/early-onset sarcoidosis (Blau/EOS) is an autoinflammatory disease characterized by granulomatous arthritis, uveitis, and skin rash. It has been shown that gain-of-function NOD2 mutations cause Blau/EOS. In this paper, we describe a patient with a gain-of-function NOD2 mutation who developed infantile Tak...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-012-0720-z

    authors: Inoue Y,Kawaguchi Y,Shimojo N,Yamaguchi K,Morita Y,Nakano T,Arima T,Tomiita M,Kohno Y

    更新日期:2013-07-01 00:00:00

  • ANCA-associated vasculitis with dual ANCA positivity in coexistence with mixed connective tissue disease.

    abstract::We here report a rare case of dual antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in a 38-year-old Japanese woman previously diagnosed with mixed connective tissue disease. The patient was found to be positive for myeloperoxidase- and proteinase 3-ANCA, and was diagnosed with AAV following admi...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1007/s10165-012-0619-8

    authors: Murakami M,Shimane K,Takahashi H,Tomiyama J,Nagashima M

    更新日期:2013-01-01 00:00:00

  • Plasma acrolein level in rheumatoid arthritis increases independently of the disease characteristics.

    abstract::Objective: This study aimed to clarify whether plasma acrolein level actually increases in rheumatoid arthritis (RA) patients, and to elucidate whether any relationship exists between the levels and the RA background variables.Methods: Plasma levels of protein-conjugated acrolein (PC-Acro) in 84 patients (RA group) an...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1080/14397595.2020.1775921

    authors: Kawabata C,Nagasawa T,Ono M,Tarumoto N,Katoh N,Hotta Y,Kawano H,Igarashi K,Shiokawa K,Nishimura K

    更新日期:2020-06-16 00:00:00

  • TAFRO syndrome: 2 cases and review of the literature.

    abstract::Recently, more than ten cases of thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome or Castleman-Kojima disease exhibiting such symptoms as thrombocytopenia, anasarca, fever, reticulin fibrosis and organomegaly have been reported in Japan. We have found two cases of TAFRO syndrome...

    journal_title:Modern rheumatology

    pub_type: 杂志文章,评审

    doi:10.3109/14397595.2015.1059982

    authors: Kawashima M,Usui T,Okada H,Mori I,Yamauchi M,Ikeda T,Kajita K,Kito Y,Miyazaki T,Fujioka K,Ishizuka T,Morita H

    更新日期:2017-11-01 00:00:00

  • Efficacy and safety of interleukin-1 inhibitors in familial Mediterranean fever patients complicated with amyloidosis.

    abstract:BACKGROUND:Colchicine is the mainstay of the treatment of familial Mediterranean fever (FMF). However, 10% of FMF patients do not respond well to colchicine. Efficacy of interleukin (IL)-1 inhibitors in reducing attacks have been demonstrated in colchicine-resistant FMF (crFMF) patients recently. Colchicine is still th...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1080/14397595.2018.1457469

    authors: Varan Ö,Kucuk H,Babaoglu H,Guven SC,Ozturk MA,Haznedaroglu S,Goker B,Tufan A

    更新日期:2019-03-01 00:00:00

  • Real-world treatment of gout and asymptomatic hyperuricemia: A cross-sectional study of Japanese health insurance claims data.

    abstract:OBJECTIVES:To assess gout and asymptomatic hyperuricemia in Japan and review treatment conditions. METHODS:This retrospective cross-sectional study analyzed the prevalence of hyperuricemia and gout, and characteristics and treatment of patients with those conditions, using Japanese health insurance claims and medical ...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1080/14397595.2020.1784556

    authors: Koto R,Nakajima A,Horiuchi H,Yamanaka H

    更新日期:2021-01-01 00:00:00

  • Clinical response among golimumab-treated Japanese patients with rheumatoid arthritis by number of previous biologic therapies: Real-world evidence from post-hoc analysis of post-marketing surveillance data.

    abstract:OBJECTIVES:To assess the real-world effectiveness of golimumab in Japanese patients with rheumatoid arthritis who had previously received one or more biologic therapies. METHODS:A post-hoc analysis of post-marketing surveillance was performed. The clinical response to golimumab was analyzed in 1216 patients who had pr...

    journal_title:Modern rheumatology

    pub_type: 杂志文章

    doi:10.1080/14397595.2020.1797283

    authors: Shimizu H,Kobayashi H,Kanbori M,Ishii Y

    更新日期:2020-08-19 00:00:00