Abstract:
:Abstract Three cases of childhood-onset systemic lupus erythematosus (childhood SLE) with long-term remission are reported. These cases were not complicated with collagen diseases and had no SLE disease activity index scores either 3 or 5 years after onset. We suggest that some patients with childhood SLE may be able to abandon the maintenance therapy, and that careful observation is needed for each individual case. Uniform remission criteria based on clinical trials are needed.
journal_name
Mod Rheumatoljournal_title
Modern rheumatologyauthors
Mori M,Kobayashi Y,Miyamae T,Imagawa T,Katakura S,Mitsuda T,Aihara Y,Yokota Sdoi
10.3109/s10165-003-0238-5subject
Has Abstractpub_date
2003-09-01 00:00:00pages
285-7issue
3eissn
1439-7595issn
1439-7609journal_volume
13pub_type
杂志文章abstract:OBJECTIVE:To assess the utilities of ultrasonography (US) and low-field magnetic resonance imaging (compacTscan, cMRI) in the diagnosis of subclinical synovitis of hand joints of patients with rheumatoid arthritis (RA). METHODS:A total of 1,540 joints of 77 RA patients were examined clinically, using US, using cMRI, a...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.854050
更新日期:2014-01-01 00:00:00
abstract::Abstract Sensitivity and specificity were compared among the American College of Rheumatology (ACR) 1987 classification criteria, the Yamasaki diagnostic criteria, and the Japan Rheumatism Association (JRA) diagnostic criteria for early rheumatoid arthritis (RA). The study included 90 patients who consulted our depart...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650070020
更新日期:2000-09-01 00:00:00
abstract:INTRODUCTION:Fibromyalgia syndrome (FMS) is a chronic disease characterized by diffuse pain of unknown cause, fatigue, sleep disorders, cognitive dysfunction, and sensitivity. Fibromyalgia was shown to be associated with balance problems and increased incidence of falls. There are many theoretical mechanisms related to...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2016.1259603
更新日期:2017-09-01 00:00:00
abstract::Spontaneous flexor tendon rupture is an unusual complication of systemic lupus erythematosus (SLE) and has not previously been reported. While tendon ruptures in association with SLE have been focused on the previous studies, upper extremity tendon ruptures are infrequently reported in the literature. Here, we present...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2014.924193
更新日期:2016-09-01 00:00:00
abstract::Leuconostoc infections are rare and usually occur in immunocompromised patients. This report describes a case of Leuconostoc lactis bacteremia in a patient with coexisting rheumatoid arthritis and tuberculosis arthritis. A disrupted gastrointestinal barrier due to gastrointestinal amyloidosis in long-standing rheumato...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-011-0465-0
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and efficacy of reducing the duration of infliximab infusion for rheumatoid arthritis (RA) treatment. METHODS:The first 6 infliximab infusions were each administered over a 2-h period. If no adverse reaction was observed, infusion times were shortened to 1 h starting with the seventh i...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.843747
更新日期:2014-03-01 00:00:00
abstract::A 68-year-old man with a fever of unknown origin was admitted to our hospital. Bilateral auricularis and nasal root inflammation, with auricular perichondritis positive for anti-type II collagen (CII) antibody, led to a diagnosis of relapsing polychondritis (RP). Because the patient was refractory for high-dose glucoc...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-011-0453-4
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVES:Modern three-component total ankle arthroplasty (TAA) has favorable clinical results and survival rates. However, radiographic deterioration and worsening of clinical symptoms may occur in patients with rheumatoid arthritis (RA) or non-inflammatory arthritis (NA). The associations between outcomes and clinic...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2016.1220049
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:The purpose of the present study was to describe our experience with the recombinant Fab' antibody fragment against TNF-α Certolizumab Pegol (CZP) in patients with Behçet's disease (BD) refractory to standardized therapies and previous biologic agents. METHODS:Retrieved data including demographic characteri...
journal_title:Modern rheumatology
pub_type: 杂志文章,多中心研究
doi:10.1080/14397595.2017.1285857
更新日期:2017-11-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a complex process of chronic and progressive inflammation associated with activation of numerous signaling molecules and transcription factors and hyperproliferation of synoviocytes of the affected joints, although the greater part of its pathophysiological process is explained by activati...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-004-0372-8
更新日期:2005-01-01 00:00:00
abstract::Abstract To clarify the effect of leukemia inhibitory factor (LIF) on the destruction of rheumatoid arthritis (RA) joints, we investigated the production of LIF and the expression of LIF mRNA in synovial tissues from patients with RA and osteoarthritis (OA). Synovial fluids from RA were used to measure the LIF concent...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s10165-002-0210-9
更新日期:2003-06-01 00:00:00
abstract::Objectives: To evaluate the effectiveness of add-on iguratimod (IGU) in patients with rheumatoid arthritis (RA) who showed an inadequate response to tocilizumab (TCZ), especially patients who were intolerant of an effective dose of methotrexate (MTX). Methods: Thirty-one patients with RA (22 women, age 62.4 years, dis...
journal_title:Modern rheumatology
pub_type: 杂志文章,多中心研究
doi:10.1080/14397595.2018.1486939
更新日期:2019-07-01 00:00:00
abstract::The association of either thrombotic thrombocytopenic purpura (TTP) or crescentic glomerulonephritis with Sjögren's syndrome is rare. We report a case of TTP appearing after the diagnosis of SjOgren's syndrome with crescentic glomerulonephritis and membranous nephropathy. Circulating immune complex was detected, and i...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-004-0287-4
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:We aimed to identify causes of false-positives in ultrasound scanning of synovial/tenosynovial/bursal inflammation and provide corresponding imaging examples. METHODS:We first performed systematic literature review to identify previously reported causes of false-positives. We next determined causes of fal...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2015.1091123
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Efficacy of anti-tumor necrosis factor (anti-TNF)α treatment in patient with active ankylosing spondylitis (AS) had been proved by many clinical studies. Inflammation and new bone formation in spine were two pivotal aspects in AS. TNF α inhibitor could eliminate inflammation including clinical and laboratory...
journal_title:Modern rheumatology
pub_type: 杂志文章,meta分析
doi:10.1080/14397595.2018.1525017
更新日期:2019-05-01 00:00:00
abstract::We here report a rare case of dual antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in a 38-year-old Japanese woman previously diagnosed with mixed connective tissue disease. The patient was found to be positive for myeloperoxidase- and proteinase 3-ANCA, and was diagnosed with AAV following admi...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-012-0619-8
更新日期:2013-01-01 00:00:00
abstract::Abstract This study examined the pathogenesis of large pseudocysts adjacent to knee joints in rheumatoid arthritis (RA). The radiological and histopathological features of 17 large subarticular pseudocysts in 12 knee joints of 10 patients were analyzed. Nine of the 10 patients were classified as class 2 according to ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650200022
更新日期:2002-06-01 00:00:00
abstract::A 10-year cohort study was performed, involving all of the 118 patients treated with bucillamine in our hospital between 1988 and 1990. Evaluation was made on the basis of erythrocyte sedimentation rate, grip strength, joint score, duration of morning stiffness, and Lansbury index consisting of the above four paramete...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-006-0533-z
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To investigate which IgG subclasses contribute to the activation of the complement pathway in IgG4-related disease (IgG4RD) patients with hypocomplementemia. METHODS:Sera of IgG4RD patients were analyzed for the binding ability of IgG subclasses to complement component 1q (C1q). Polyethylene glycol (PEG) pre...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2015.1076924
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Colchicine is the mainstay of the treatment of familial Mediterranean fever (FMF). However, 10% of FMF patients do not respond well to colchicine. Efficacy of interleukin (IL)-1 inhibitors in reducing attacks have been demonstrated in colchicine-resistant FMF (crFMF) patients recently. Colchicine is still th...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2018.1457469
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:This study aimed to identify the prevalence of scoliosis and scoliosis-related factors of rheumatoid arthritis (RA). METHODS:In this study, 411 patients who underwent coronal total spine and lower limb radiography were enrolled. Patients with a Cobb angle ≥10° were diagnosed with scoliosis. Statistical anal...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2015.1097016
更新日期:2016-01-01 00:00:00
abstract::Nintedanib (Ofev™), an oral triple kinase inhibitor targeting pro-fibrotic pathways, has been used for treatment of idiopathic pulmonary fibrosis (IPF). Based on positive results from phase III, placebo-controlled, randomized comparative clinical trial conducted in patients with systemic sclerosis-associated interstit...
journal_title:Modern rheumatology
pub_type: 杂志文章,评审
doi:10.1080/14397595.2019.1696505
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:To retrospectively evaluate whether oral glucocorticoid (GC) administration can be tapered or discontinued over a 2-year observation period in patients with rheumatoid arthritis (RA) undergoing a stable oral GC treatment, without deterioration in the disease status. METHODS:Methotrexate (MTX) and prednisolon...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2020.1864914
更新日期:2020-12-16 00:00:00
abstract::Here, we report the case of a 69-year-old man with limited granulomatosis with polyangiitis (GPA; formerly Wegener's granulomatosis) who developed papillary thyroid cancer, adenocarcinoma of the stomach, and myelodysplastic syndrome following glucocorticoid treatment. This is the first report to present multiple malig...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2014.891494
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:To determine whether ultrasonography (US) predicts Boolean remission in rheumatoid arthritis (RA) patients who had achieved disease activity score in 28 joints (DAS28)-based remission criteria. METHODS:Thirty-one RA patients in DAS28-based clinical remission were recruited. US semiquantitatively determined ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.857800
更新日期:2014-07-01 00:00:00
abstract::The aim of our study was to determine the spectrum of the 12 most common familial Mediterranean fever gene (MEFV) mutations in Iranian patients with heterogeneous ethnicity, using the familial Mediterranean fever (FMF) strip assay test. A total of 36 patients were diagnosed according to established clinical criteria. ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-010-0317-3
更新日期:2010-12-01 00:00:00
abstract::We present the case of a 60-year-old female patient with systemic sclerosis complicated by pulmonary hypertension. Ten days after the initiation of treatment with bosentan, high fever and skin eruptions were noted. In the previous reports, the frequency of drug-induced skin eruptions has not been well documented. Sinc...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-006-0477-3
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:The present study aimed to conduct an epidemiological survey of Central Sensitization Inventory (CSI) scores in an older adult population and to investigate the association between the CSI scores, age, sex, pain intensity, site of pain, and health-related quality of life (QOL). METHODS:Participants were 373...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2020.1822983
更新日期:2020-10-02 00:00:00
abstract:OBJECTIVES:To develop and evaluate an exercise program that the elderly could sustainably perform in the community or at home to recover from locomotive syndrome. METHODS:We produced 2 types of teaching media, video and pamphlet, describing 10 physical and mobility training exercises. The pilot study examined changes ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.854063
更新日期:2014-03-01 00:00:00
abstract::Anti-tumor necrosis factor (anti-TNF) biologics are effective in the treatment of rheumatoid arthritis (RA); however, it is still not clear whether this treatment promotes the development of malignancies such as lymphoma. Human T-lymphotropic virus type 1 (HTLV-1), which is a causative agent of adult T-cell lymphoma (...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.844389
更新日期:2015-09-01 00:00:00