Abstract：
OBJECTIVE(S):Garlic (Allium sativum L. family Liliaceae) is well known in Iran and its leaves, flowers, and cloves have been used in traditional medicine for a long time. Research in recent decades has shown widespread pharmacological effects of A. sativum and its organosulfur compounds especially Allicin. Studies carried out on the chemical composition of the plant show that the most important constituents of this plant are organosulfur compounds such as allicin, diallyl disulphide, S-allylcysteine, and diallyl trisulfide. Allicin represents one of the most studied among these naturally occurring compounds. In addition to A. sativum, these compounds are also present in A. hirtifolium (shallot) and have been used to treat various diseases. This article reviews the pharmacological effects and traditional uses of A. sativum, A. hirtifolium, and their active constituents to show whether or not they can be further used as potential natural sources for the development of novel drugs. MATERIALS AND METHODS:For this purpose, the authors went through a vast number of sources and articles and all needed data was gathered. The findings were reviewed and classified on the basis of relevance to the topic and a summary of all effects were reported as tables. CONCLUSION:Garlic and shallots are safe and rich sources of biologically active compounds with low toxicity. Further studies are needed to confirm the safety and quality of the plants to be used by clinicians as therapeutic agents.
journal_name
Iran J Basic Med Scijournal_title
Iranian journal of basic medical sciencesauthors
Mikaili P,Maadirad S,Moloudizargari M,Aghajanshakeri S,Sarahroodi Ssubject
Has Abstractpub_date
2013-10-01 00:00:00pages
1031-48issue
10eissn
2008-3866issn
2008-3874journal_volume
16pub_type
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journal_title：Iranian journal of basic medical sciences
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journal_title：Iranian journal of basic medical sciences
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更新日期：2019-06-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
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journal_title：Iranian journal of basic medical sciences
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
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更新日期：2017-10-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
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更新日期：2016-01-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
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更新日期：2018-03-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
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更新日期：2016-08-01 00:00:00
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更新日期：2017-02-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：10.22038/ijbms.2018.25399.6280
更新日期：2018-03-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：
更新日期：2015-11-01 00:00:00
abstract：Objectives:Cord blood (CB) is known as a valuable source of hematopoietic stem cells (HSC). Identifying strategies that enhance expansion and maintain engraftment and homing capacity of HSCs can improve transplant efficiency. In this study, we examined different culture conditions on ex vivo expansion and homing capaci...
journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：10.22038/IJBMS.2018.26820.6561
更新日期：2018-07-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：
更新日期：2011-09-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：
更新日期：2013-02-01 00:00:00
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pub_type： 杂志文章
doi：
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pub_type： 杂志文章
doi：
更新日期：2016-04-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章,评审
doi：
更新日期：2013-03-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：10.22038/IJBMS.2018.22877.5816
更新日期：2018-09-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：
更新日期：2016-11-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2019-07-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：
更新日期：2016-04-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：10.22038/ijbms.2016.7911
更新日期：2016-12-01 00:00:00
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journal_title：Iranian journal of basic medical sciences
pub_type： 杂志文章
doi：10.22038/IJBMS.2019.37561.8989
更新日期：2020-02-01 00:00:00
