Effect of sodium hydrosulfide on mRNA expression of prostaglandin E2 receptors in response to mucosal acidification and distention-induced gastric acid secretion in rats.

abstract：OBJECTIVES:To study the effect of low-frequency vibration on bone marrow stromal cell differentiation and potential bone repair in vivo. MATERIALS AND METHODS:Forty New Zealand rabbits were randomly divided into five groups with eight rabbits in each group. For each group, bone defects were generated in the left humer...

journal_title：Iranian journal of basic medical sciences

authors： He S,Zhao W,Zhang L,Mi L,Du G,Sun C,Sun X

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE(S):The effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study. MATERIALS AND METHODS:Male Wistar rats were randomly divided into control sedentary (C), moderate trained (MT), (V=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (OT) (V=25 m/...

journal_title：Iranian journal of basic medical sciences

authors： Gholamnezhad Z,Boskabady MH,Hosseini M,Sankian M,Khajavi Rad A

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to prepare, characterize, and evaluate solid lipid nanoparticles (SLNs) containing Zataria multiflora essential oil (ZEO). MATERIALS AND METHODS:In this study, Z. multiflora essential oil-loaded solid lipid nanoparticles (ZE-SLNs) were prepared to improve its efficiency in c...

journal_title：Iranian journal of basic medical sciences

authors： Nasseri M,Golmohammadzadeh S,Arouiee H,Jaafari MR,Neamati H

更新日期：2016-11-01 00:00:00

abstract：Objectives:In this study, we investigated the protective effects of piperine on lead acetate-induced renal damage in rat kidney tissue. Materials and Methods:Forty male rats were divided into 5 groups: negative control (rats were given aquadest daily), positive control (rats were given lead acetate 30 mg/kg BW orally ...

journal_title：Iranian journal of basic medical sciences

authors： Sudjarwo SA,Eraiko K,Sudjarwo GW,Koerniasari

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVES:Particulate matter (PM) exposure can promote cardiac ischemia and myocardial damage. The effects of PM10 on hemodynamic parameters, lipid peroxidation, and infarct size induced by ischemia-reperfusion injury and the protective effects of vanillic acid (VA) in isolated rat heart were investigated. MATERIALS ...

journal_title：Iranian journal of basic medical sciences

authors： Radmanesh E,Dianat M,Badavi M,Goudarzi G,Mard SA

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE(S):Staphylococcus aureus is both a successful human commensal and a major pathogen. In this study we investigated the genetic diversity of 26 S. aureus isolates recovered from human skin and urinary tract infections. MATERIALS AND METHODS:Typing procedure for the studied S. aureus isolates was performed base...

journal_title：Iranian journal of basic medical sciences

authors： Talebi-Satlou R,Ahmadi M,Ghavam F,Saei HD

更新日期：2012-07-01 00:00:00

abstract：Objectives:Ferula ovina is an Iranian medicinal plant. Tschimgine and stylosin are two of its major monoterpene derivatives. In this study, we proceeded to investigate some fungal endophytes from F. ovina that can produce plant secondary metabolites. Materials and Methods:The isolated endophytic fungi were fermented i...

journal_title：Iranian journal of basic medical sciences

authors： Tazik Z,Rahnama K,White JF,Soltanloo H,Hasanpour M,Iranshahi M

更新日期：2020-12-01 00:00:00

abstract：Objectives:Association of adolescent emotional stress (ES) with the incidence of cardiovascular disease (CVD) at older age was investigated. Materials and Methods:21 female rats were divided into three groups of 7 each; ES, foot-shock, and control. Chronic ES was induced by exposing the rats to witness foot-shock of t...

journal_title：Iranian journal of basic medical sciences

authors： Mousavi MS,Imani A,Meknatkhah S,Riazi G

更新日期：2019-10-01 00:00:00

abstract：Objectives:Adipose-derived stem cells (ADSCs), with suitable and easy access, are multipotential cells that have the ability for differentiation into other mesodermal and transdifferentiate into neural phenotype cells. In this study, Lithium chloride (LiCl) was used for in vitro transdifferentiation of rat ADSCs into n...

journal_title：Iranian journal of basic medical sciences

authors： Farrokhfar S,Tiraihi T,Movahedin M,Azizi H

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:Naringin has been reported to regulate bone metabolism. However, its effect on osteogenesis remains unclear. The aim was to investigate the effect of naringin on osteogenic differentiation of human bone marrow mesenchymal stem cells (hBMSCs) through the activation of the ERK signaling pathway in osteogenic d...

journal_title：Iranian journal of basic medical sciences

authors： Wang H,Li C,Li J,Zhu Y,Jia Y,Zhang Y,Zhang X,Li W,Cui L,Li W,Liu Y

更新日期：2017-04-01 00:00:00

abstract：Objectives:Cord blood (CB) is known as a valuable source of hematopoietic stem cells (HSC). Identifying strategies that enhance expansion and maintain engraftment and homing capacity of HSCs can improve transplant efficiency. In this study, we examined different culture conditions on ex vivo expansion and homing capaci...

journal_title：Iranian journal of basic medical sciences

authors： Mohammadali F,Abroun S,Atashi A

更新日期：2018-07-01 00:00:00

abstract：Objectives:Cholinergic neurons are important neurons in the Pedunculopontine tegmental nucleus (PPT). In this study, nicotinic receptor of the PPT in central cardiovascular regulation in the anesthetized rat was evaluated. Materials and Methods:Saline, acetylcholine (Ach; doses: 90 and 150 nmol), hexamethonium (Hexa; ...

journal_title：Iranian journal of basic medical sciences

authors： Nikyar T,Hosseini M,Niazmand S,Shafei MN

更新日期：2018-04-01 00:00:00

abstract：Objectives:The present study investigated the prevalence of genes encoding for exotoxins, adhesion and biofilm factors in Staphylococcus aureus isolates obtained from samples in a referral burn hospital in Tehran, Iran. Materials and Methods:S. aureus isolates obtained from patients, personnel and surfaces in the ward...

journal_title：Iranian journal of basic medical sciences

authors： Mir Z,Nodeh Farahani N,Abbasian S,Alinejad F,Sattarzadeh M,Pouriran R,Dahmardehei M,Mirzaii M,Khoramrooz SS,Darban-Sarokhalil D

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:In food industry, the inhibition of tyrosinase is very important, because this enzyme catalyzes the oxidation of phenolic compounds found in fruits and vegetables into quinones, which contribute in undesirable color and taste of fruits and vegetables. Teucrium polium L. var. gnaphalodes (Lamiaceae), a wild-g...

journal_title：Iranian journal of basic medical sciences

authors： Boghrati Z,Naseri M,Rezaie M,Pham N,Quinn RJ,Tayarani-Najaran Z,Iranshahi M

更新日期：2016-08-01 00:00:00

abstract：Objectives:Periodontal diseases are among prevalent oral health problems which may ultimately lead to severe complications in oral cavity. Herbal products can be designed as single or multicomponent preparations for better oral health. This study aims to review current clinical trials on the effectiveness of herbal pro...

journal_title：Iranian journal of basic medical sciences

authors： Safiaghdam H,Oveissi V,Bahramsoltani R,Farzaei MH,Rahimi R

更新日期：2018-10-01 00:00:00

abstract：Objectives:Neurodegeneration is an outcome of Methamphetamine (METH) abuse. Studies have emphasized on the neuroprotective properties of lithium. The current study is designed towards evaluating the role of Akt-1/GSK3 and CREB-BDNF signaling pathways in mediating lithium neuroprotection against METH-induced neurodegene...

journal_title：Iranian journal of basic medical sciences

authors： Mehrafza S,Kermanshahi S,Mostafidi S,Motaghinejad M,Motevalian M,Fatima S

更新日期：2019-08-01 00:00:00

abstract：Objectives:A growing body of evidence indicates that rhomboid domain containing 1 (RHBDD1) plays an important role in a variety of physiological and pathological processes, including tumorigenesis. We aimed to determine the function of RHBDD1 in breast cancer cells. Materials and Methods:In this study, we used the Onc...

journal_title：Iranian journal of basic medical sciences

authors： Huang C,Ji X,Peng Y,Wu M,Wu W,Luo Y,Cheng G,Zhu Y

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:The purpose of the current study was to assess the feasibility of microspheres from biocompatible polymer for oral bioavailability (BA) enhancement of potent sulfonamide- type loop diuretic- Furosemide - which used in the treatment of congestive heart failure, caused edema, cirrhosis, renal disease and as an...

journal_title：Iranian journal of basic medical sciences

authors： Derakhshandeh K,Karimi M,Azandaryani AH,Bahrami G,Ghanbari K

更新日期：2016-10-01 00:00:00

abstract：Objectives:Gallic acid (GA) is a highly effective antioxidant, which its beneficial effects are well known, but its impact on expression of microRNAs (miRs) following hepatic ischemia-reperfusion (I/R) is not well recognized. Therefore, the current research was designed to specify the beneficial effect of GA on miRs (1...

journal_title：Iranian journal of basic medical sciences

authors： Akbari G,Savari F,Mard SA,Rezaie A,Moradi M

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVES:Crocin bleaching assay (CBA) is a new method for determination of antioxidant capacity. In CBA, addition of hydrogen to the conjugated double bonds of crocin results in reduction of crocin and increase in the absorbance at 440 nm, which is considered as a measure of antioxidant potential. Here CBA method was...

journal_title：Iranian journal of basic medical sciences

authors： Bathaie SZ,Shams A,Moghadas Zadeh Kermani F

更新日期：2011-09-01 00:00:00

abstract：:Metastasis is the primary cause of mortality and morbidity among cancer patients and accounts for about 90% of cancer deaths. The most common types of treatment for cancer metastasis are chemotherapy and radiotherapy. However, such therapy has many serious side effects that could diminish the quality of life in patien...

journal_title：Iranian journal of basic medical sciences

authors： Ahmadiankia N

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE(S):Garlic (Allium sativum L. family Liliaceae) is well known in Iran and its leaves, flowers, and cloves have been used in traditional medicine for a long time. Research in recent decades has shown widespread pharmacological effects of A. sativum and its organosulfur compounds especially Allicin. Studies carr...

journal_title：Iranian journal of basic medical sciences

authors： Mikaili P,Maadirad S,Moloudizargari M,Aghajanshakeri S,Sarahroodi S

更新日期：2013-10-01 00:00:00

abstract：:Klotho (KL) encodes a single-pass transmembrane protein and is predominantly expressed in the kidney, parathyroid glands, and choroid plexus. Genetic studies on the KL gene have revealed that DNA hypermethylation is one of the major risk factors for aging, diseases, and cancer. Besides, KL exerts anti-inflammatory and...

journal_title：Iranian journal of basic medical sciences

authors： Xuan NT,Hai NV

更新日期：2018-01-01 00:00:00

abstract：Objectives:Recent evidence has shown underlying roles of gut dysbiosis and metabolic endotoxemia in obesity and its complications. Despite the large number of experimental and clinical researches performed on gut microbiota and obesity, no bibliometrics' study has been conducted so far. We aimed to assess the trend of ...

journal_title：Iranian journal of basic medical sciences

authors： Ejtahed HS,Tabatabaei-Malazy O,Soroush AR,Hasani-Ranjbar S,Siadat SD,Raes J,Larijani B

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Pharmacological studies showed that the extracts of Jin Yin Hua and its active constituents have lipid lowering, antipyretic, hepatoprotective, cytoprotective, antimicrobial, antibiotic, antioxidative, antiviral, and anti-inflammatory effects. The purpose of the present study was to investigate the protectiv...

journal_title：Iranian journal of basic medical sciences

authors： Wang C,Wang G,Liu H,Hou YL

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:In previous studies, researchers observed that doxepin could improve cognitive processes and has protective effects on the central nervous system. Thus, this study was designed to analyze the effects of doxepin on β-amyloid (Aβ)-induced memory impairment and neuronal toxicity in rat and to explore the underl...

journal_title：Iranian journal of basic medical sciences

authors： Bu J,Zu H

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate the relationship between insulin resistance (IR) and leptin (LEP) gene polymorphisms in peritoneal dialysis (PD) patients. MATERIALS AND METHODS:From July 1, 2011 to August 1, 2011, patients who received chronic PD were chosen and divided into three groups (DM, high H...

journal_title：Iranian journal of basic medical sciences

authors： Cao L,Mou S,Fang W,Qi C,Chang X,Gu L,Qian J,Ni Z

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:The primary objective of this study was to determine whether local and imported cigarette brands used in , have elevated levels of metals or not. The produced data of cigarette brands are compared both with each other and with the existing brands in different countries. MATERIALS AND METHODS:In present stud...

journal_title：Iranian journal of basic medical sciences

authors： Pourkhabbaz A,Pourkhabbaz H

更新日期：2012-01-01 00:00:00

abstract：Objectives:Traumatic brain injury (TBI) is one of the main causes of intellectual and cognitive disabilities. Clinically, it is essential to limit the development of cognitive impairment after TBI. In the present study, the neuroprotective effects of gallic acid (GA) on neurological score, memory, long-term potentiatio...

journal_title：Iranian journal of basic medical sciences

authors： Mirshekar MA,Sarkaki A,Farbood Y,Gharib Naseri MK,Badavi M,Mansouri MT,Haghparast A

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:Production of extended-spectrum beta-lactamases (ESBLs) by enteric bacteria continues to be a major problem in hospitals and community. ESBLs producing bacteria cause many serious infections including urinary tract infections, peritonitis, cholangitis and intra-abdominal abscess. The aim of this study was to...

journal_title：Iranian journal of basic medical sciences

authors： Zaniani FR,Meshkat Z,Naderi Nasab M,Khaje-Karamadini M,Ghazvini K,Rezaee A,Esmaily H,Nabavinia MS,Darban Hoseini M

更新日期：2012-01-01 00:00:00