Abstract：
:Unruptured intracranial aneurysms represent a decisional challenge. Treatment risks have to be balanced against an unknown probability of rupture. A better understanding of the physiopathology is the basis for a better prediction of the natural history of an individual patient. Knowledge about the possible determining factors arises from a careful comparison between ruptured versus unruptured aneurysms and from the prospective observation and analysis of unbiased series with untreated, unruptured aneurysms. The key point is the correct identification of the determining variables for the fate of a specific aneurysm in a given individual. Thus, the increased knowledge of mechanisms of formation and eventual rupture of aneurysms should provide significant clues to the identification of rupture-prone aneurysms. Factors like structural vessel wall defects, local hemodynamic stress determined also by peculiar geometric configurations, and inflammation as trigger of a wall remodeling are crucial. In this sense the study of genetic modifiers of inflammatory responses together with the computational study of the vessel tree might contribute to identify aneurysms prone to rupture. The aim of this article is to underline the value of a unifying hypothesis that merges the role of geometry, with that of hemodynamics and of genetics as concerns vessel wall structure and inflammatory pathways.
journal_name
Neurosurg Revjournal_title
Neurosurgical reviewauthors
Bacigaluppi S,Piccinelli M,Antiga L,Veneziani A,Passerini T,Rampini P,Zavanone M,Severi P,Tredici G,Zona G,Krings T,Boccardi E,Penco S,Fontanella Mdoi
10.1007/s10143-013-0501-ysubject
Has Abstractpub_date
2014-01-01 00:00:00pages
1-14issue
1eissn
0344-5607issn
1437-2320journal_volume
37pub_type
杂志文章,评审abstract：:It is well known that radiation can induce meningiomas. These tumors usually arise in patients with a history of low-dose radiation to the scalp for treatment of tinea capitis or high-dose radiation for a previous brain tumor. Radiation-associated meningiomas (RAMs) morphologically resemble their spontaneously arising...
journal_title：Neurosurgical review
pub_type： 杂志文章,评审
doi：10.1007/s10143-004-0366-1
更新日期：2005-04-01 00:00:00
abstract：:The purpose of this study is to describe our series of nine unclippable and uncoilable ruptured aneurysms in eight patients treated by microsurgical wrapping with autologous muscle. Records were retrospectively reviewed for rebleeding rate, morbidity and mortality, changes in size or the aneurysm's configurations, and...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-012-0408-z
更新日期：2013-01-01 00:00:00
abstract：:Hemangioblastoma is a rare benign tumor that consists of neoplastic vacuolated stromal cells and highly developed capillary blood vessels. These tumors are almost exclusively found in the central nervous system, but in extremely rare cases, it can arise in peripheral nerves. In the majority of cases, it occurs sporadi...
journal_title：Neurosurgical review
pub_type： 杂志文章,评审
doi：10.1007/s10143-014-0587-x
更新日期：2015-01-01 00:00:00
abstract：:The purpose of this study was to determine the effect of aspirin therapy discontinuation on intraoperative blood loss in spinal surgery. We searched Medline and Google Scholar 1946 to January 2017 inclusive for case-control studies, cohort studies, and controlled trials reporting intraoperative blood loss during spina...
journal_title：Neurosurgical review
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s10143-018-0945-1
更新日期：2018-10-01 00:00:00
abstract：:The purpose of the present study is to analyze the impact of intraoperative resection control modalities on overall survival (OS) and progression-free survival (PFS) following gross total resection (GTR) of glioblastoma. We analyzed data of 76 glioblastoma patients (30f, mean age 57.4 ± 11.6 years) operated at our ins...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-015-0698-z
更新日期：2016-07-01 00:00:00
abstract：:Magnesium has neuroprotective and antivasospastic properties in the presence of subarachnoid hemorrhage (SAH). The present study investigated the effect of intracisternal administration of magnesium on cerebral vasospasm in the experimental SAH rat model. The rat double-SAH model (0.2 mL autologous blood injected twic...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-008-0122-z
更新日期：2008-04-01 00:00:00
abstract：:Superficial temporal artery-middle cerebral artery (STA-MCA) anastomosis is a safe and effective treatment for moyamoya disease, although recent evidence suggests its substantial risk for symptomatic cerebral hyperperfusion. The diagnostic value of single-photon emission computed tomography (SPECT) for postoperative h...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-008-0147-3
更新日期：2008-10-01 00:00:00
abstract：:The endoscope has become an essential tool for transsphenoidal pituitary surgeries because of the panoramic view and the ability to visualize structures beyond the direct line of vision. However, the regular dedicated instruments for these surgeries sometimes do not reach the areas visualized by an angled endoscope, a...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-007-0108-2
更新日期：2008-01-01 00:00:00
abstract：:Twenty patients with severe head injury were analysed as to whether they developed a humoral immunodeficiency syndrome. In spite of the fact that 75% developed pyogenic complications all patients showed a polyclonal humoral activation of their immune system with an increase in IgG, IgA, IgM and the complement factors....
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01790685
更新日期：1989-01-01 00:00:00
abstract：:Chemotherapy of malignant glioma has been discussed in relation to recent advances in experimental and clinical studies. It is now obvious that chemotherapy is of increasing importance in the multidisciplinary treatment of malignant gliomas. Survival time of patients was prolonged by intensive and prolonged chemothera...
journal_title：Neurosurgical review
pub_type： 临床试验,杂志文章,评审
doi：10.1007/BF01743285
更新日期：1984-01-01 00:00:00
abstract：:Sinus pericranii is a rare vascular abnormality characterised by abnormal connections between the intra- and extracranial venous systems and is usually found in children. In most instances, a sinus pericranii presents as a soft scalp swelling that appears with the patient in the recumbent position and disappears in th...
journal_title：Neurosurgical review
pub_type： 杂志文章,评审
doi：10.1007/s10143-011-0325-6
更新日期：2012-01-01 00:00:00
abstract：:A patients with a giant fusiform aneurysm of the left inferior trunkus of the middle cerebral artery (MCA) is presented. The size of the aneurysm was 5 cm at its largest diameter. Retrograde flow was well developed. After the application of temporary clips the aneurysm was excised and microsurgical reconstructions wer...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF02389331
更新日期：1998-01-01 00:00:00
abstract：:A primary xanthomatous tumor is very rare in the central nervous system (CNS). Here we report the case of a fibroxanthoma arising from the dura mater of the cerebrum that demonstrated no systemic disease or metabolic abnormalities. A 19-month-old, otherwise healthy boy was found to have an enlarged head. Magnetic reso...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s101430050019
更新日期：1999-12-01 00:00:00
abstract：:Spinal cord or cauda equina compression (SCC) is an increasing challenge in clinical oncology due to a higher prevalence of long-term cancer survivors. Our aim was to determine the clinical relevance of SCC regarding patient outcome depending on different tumor entities and their anatomical localization (extradural/in...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-016-0790-z
更新日期：2017-07-01 00:00:00
abstract：:A retrospective study was conducted on 67 patients undergoing posterior cervical foraminotomy (PCF) for unilateral intraforaminal soft and hard disc disease. Neurologic impairment, employment, and severity of associated signs were assessed preoperatively and at a 3.1-year average follow-up (range, 1.5-7 years). Diminu...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/pl00011957
更新日期：2000-12-01 00:00:00
abstract：:Three of 30 human cerebral cortex biopsies from infants treated for hydrocephalus by shunt operation are described. The descriptions include an account of their case history, the clinical methods, and the operational procedures. The biopsy specimens were studied in semithin and ultrathin sections. Attention is drawn t...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01741422
更新日期：1988-01-01 00:00:00
abstract：:The pattern of hormone secretion by human pituitary tumours in cell or explant culture has been shown to be of value in establishing the nature of the tissue. There was complete agreement between the diagnosis reached by conventional immunocytochemical techniques and by examining the secretion of hormones in culture. ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01815438
更新日期：1985-01-01 00:00:00
abstract：:A multidimensional concept of diagnosis and treatment of mental disorders is presented. Major contributions to basic research come from pharmacological experiments. Clinical outcome in treatment of endogenous depression can be assessed by rating scales and psychophysiological tests and correlated with the serum level ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01650030
更新日期：1980-01-01 00:00:00
abstract：:Growing evidence from recent studies have revealed that long non-coding RNA (lncRNA) might be a useful prognostic biomarker for glioma; we therefore conducted the current meta-analysis to evaluate prognostic and clinicopathological predictive value of lncRNA expression for glioma patients. Eligible studies were identi...
journal_title：Neurosurgical review
pub_type： 杂志文章,meta分析
doi：10.1007/s10143-018-0965-x
更新日期：2020-02-01 00:00:00
abstract：:Patients with craniocervical disorders (CCD) show a wide variety of symptoms and signs suggesting cerebellar and/or high cervical lesion. The anatomic localization of respiratory centers and their possible injury may explain the presence of respiratory disturbances in these diseases. The aim of this preliminary study ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/pl00011947
更新日期：2000-09-01 00:00:00
abstract：:Dissecting aneurysms in the anterior cerebral artery (ACA), although rare, can cause ischemic and/or hemorrhagic stroke. Hemorrhagic dissecting aneurysms in the A1 portion of the ACA are often associated with a poor prognosis. We retrospectively investigated three rare cases of hemorrhagic dissecting aneurysms in the ...
journal_title：Neurosurgical review
pub_type： 杂志文章,评审
doi：10.1007/s10143-017-0841-0
更新日期：2018-04-01 00:00:00
abstract：:Experimental brain tumours were produced in cats by stereotactic implantation of 4 million suspended cells of a rat glioma clone into the internal capsule. Three weeks after implantation a spherical tumour developed with a diameter of up to 10 mm which was surrounded by vasogenic white matter oedema. In untreated anim...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01743708
更新日期：1981-01-01 00:00:00
abstract：:The aim of this study was to perform a morphometric analysis of untreated adult skulls displaying syndromic and nonsyndromic craniosynostosis. We analyzed, in detail, 42 adult craniosynostoses (18 scaphocephaly, 11 anterior plagiocephaly, 2 trigonocephaly, 9 oxycephaly, and 2 brachycephaly) from archeological (three s...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-007-0100-x
更新日期：2008-04-01 00:00:00
abstract：:The optimal management of cranioplasty infections remains a matter of debate. Most authors have suggested that the infected bone/implant removal is mandatory, combined with prolonged antibiotic therapy before reconstruction. However, failures can occur, even with 12-18-month intervals between the surgeries. Longer wai...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-020-01341-z
更新日期：2020-06-26 00:00:00
abstract：:Hemorrhagic complication is one of the notable surgical complications of the revascularization surgery for moyamoya disease (MMD). Cerebral hyperperfusion (CHP) has been considered as the underlying cause of this complication. It mostly occurs several days after surgery, but the intra-operative hemorrhage immediately ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-017-0868-2
更新日期：2017-10-01 00:00:00
abstract：:The measurement of cerebral blood flow (CBF) in addition to cerebral computerized tomography (CT) and angiography is most reliable in cases of transient ischemic attacks (TIA) and prolonged reversible ischemic neurologic deficits (PRIND). Alterations of CBF can be detected in symptom-free intervals. The cerebrovascula...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF01781948
更新日期：1987-01-01 00:00:00
abstract：:Surgery is the only therapeutic option for cerebral cavernous malformations (CCM) and is proposed, whenever possible, after haemorrhagic events, neurological symptoms, or epilepsy, radiosurgery being a controversial alternative in some cases. However, there is no treatment for non-accessible lesions, such as brainstem...
journal_title：Neurosurgical review
pub_type： 杂志文章,评审
doi：10.1007/s10143-018-01074-0
更新日期：2019-06-01 00:00:00
abstract：:Injury to the internal carotid artery (ICA) is a life-threatening complication of endoscopic endonasal approaches. The objective of this study is to illustrate the detail anatomy of the parapharyngeal segment of the ICA (PPICA) to safe endoscopic endonasal surgery. The anatomical dissection was performed in 10 cadaver...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/s10143-019-01176-3
更新日期：2020-10-01 00:00:00
abstract：:Three patients suffering from hematogenous destructive spondylodiscitis were treated with one-session spondylectomy, bone graft-fusion and halo-device stabilization. A stable osseous fusion was achieved after three months with additional antibiotic therapy. ...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/BF00338196
更新日期：1991-01-01 00:00:00
abstract：:The number of patients undergoing surgical treatment for pharmacoresistant temporal lobe epilepsy is rapidly increasing. While there have been many clinicopathological studies concerning the medial structures of the temporal lobe in temporal lobe epilepsy, its lateral structures have received little attention. To exam...
journal_title：Neurosurgical review
pub_type： 杂志文章
doi：10.1007/pl00021698
更新日期：2000-06-01 00:00:00
