Intracisternal infusion of magnesium sulfate solution improved reduced cerebral blood flow induced by experimental subarachnoid hemorrhage in the rat.

Abstract:

:Magnesium has neuroprotective and antivasospastic properties in the presence of subarachnoid hemorrhage (SAH). The present study investigated the effect of intracisternal administration of magnesium on cerebral vasospasm in the experimental SAH rat model. The rat double-SAH model (0.2 mL autologous blood injected twice into the cisterna magna) was used. Normal saline (SAH group, N=8) or 10 mmol/L magnesium sulfate in normal saline (SAH + MG group, N=8) was infused into the cisterna magna at 1.5 microL/min for 30 min on day 5. Control rats without SAH also received intracisternal infusion of normal saline (control group, N=6). Local cerebral blood flow (CBF) at 24 locations and the weighted average were quantitatively measured by the autoradiographic technique using [(14)C]iodoantipyrine during infusion. The weighted average CBF was significantly reduced (P<0.01, Student's t-test) in the SAH group (0.78+/-0.16 mL g(-1) min(-1)) compared to the control group (1.0+/-0.15 mL g(-1) min(-1)) and was significantly improved (P<0.01, Student's t-test) in the SAH + MG group (0.98+/-0.18 mL g(-1) min(-1)). Local CBF was significantly reduced (P<0.05, unpaired t test) in 16 locations in the SAH group and significantly improved (P < 0.05, unpaired t test) in 12 locations in the SAH + MG group. Intracisternal infusion of magnesium sulfate significantly improved reduced CBF induced by experimental SAH in the rat.

journal_name

Neurosurg Rev

journal_title

Neurosurgical review

authors

Mori K,Miyazaki M,Iwata J,Yamamoto T,Nakao Y

doi

10.1007/s10143-008-0122-z

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

197-203; discussion 203

issue

2

eissn

0344-5607

issn

1437-2320

journal_volume

31

pub_type

杂志文章
  • Functional imaging of the brain in psychiatry--mapping of EEG and evoked potentials.

    abstract::Topographic brain mapping of EEG and evoked potentials permits the display of spontaneous and event-related activity of the brain. This new method is superior to conventional polygraphy because of the topographic approach which delineates structural and functional brain lesions. Data from 16 to 20 scalp electrodes wer...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF01781950

    authors: Maurer K,Dierks T

    更新日期:1987-01-01 00:00:00

  • Identification of hypoxia-induced genes in a malignant glioma cell line (U-251) by cDNA microarray analysis.

    abstract::Overcoming the metabolic restrictions of hypoxia may allow the progression of lower-grade tumors to glioblastoma multiforme. Our findings of up-regulation of HIF-1alpha and its downstream targets VEGF, GLUT-1, and CAIX in higher-grade gliomas support this hypothesis. We compared the gene expression profiles of the U-2...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-007-0070-z

    authors: Ragel BT,Couldwell WT,Gillespie DL,Jensen RL

    更新日期:2007-07-01 00:00:00

  • The value of spinal magnetic resonance imaging (MRI) in locating prolapses of lumbar intervertebral discs.

    abstract::Between 1986 and 1988 100 patients in whom MRI had been used to diagnose prolapses of lumbar intervertebral discs were admitted to the neurosurgical department of the Munich Technical University. MRI proved to be a valuable diagnostic technique, even if one has to concede certain limitations to the usefulness of the r...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF00383835

    authors: Trappe AE,Frank AM,Weinzierl FX,Obletter N

    更新日期:1993-01-01 00:00:00

  • Hypothalamic hamartoma: the role of surgery.

    abstract::A hypothalamic hamartoma associated with true precocious puberty in a 7-month-old girl is hereby reported. Hormonal studies disclosed elevated serum levels of luteinizing hormone (LH) and follicle stimulating hormone, both of which responded well to LH-releasing hormone stimulation. Following a subtotal removal of the...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF00258250

    authors: Nishio S,Shigeto H,Fukui M

    更新日期:1993-01-01 00:00:00

  • The role of brachytherapy in the treatment of glioblastoma multiforme.

    abstract::Brachytherapy (BT) for glioblastoma multiforme (GBM) involves the use of radioactive isotopes to deliver ionizing radiation directly into the tumor bed. Its application as a means to prolong survival in GBM patients over the past few decades has come with variable success. The objective of this review is to describe t...

    journal_title:Neurosurgical review

    pub_type: 杂志文章,评审

    doi:10.1007/s10143-016-0727-6

    authors: Barbarite E,Sick JT,Berchmans E,Bregy A,Shah AH,Elsayyad N,Komotar RJ

    更新日期:2017-04-01 00:00:00

  • Diffusion-weighted imaging and the apparent diffusion coefficient on 3T MR imaging in the differentiation of craniopharyngiomas and germ cell tumors.

    abstract::The apparent diffusion coefficient (ADC) on diffusion-weighted imaging (DWI) plays an important role in diagnosing intracranial tumors and predicting the histopathological grade of the tumor. However, the differences in the ADC values between craniopharyngiomas and germ cell tumors (GCTs) have not been clarified. We t...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-015-0660-0

    authors: Kinoshita Y,Yamasaki F,Tominaga A,Ohtaki M,Usui S,Arita K,Sugiyama K,Kurisu K

    更新日期:2016-04-01 00:00:00

  • Comparing navigated transcranial magnetic stimulation mapping and "gold standard" direct cortical stimulation mapping in neurosurgery: a systematic review.

    abstract::The objective of this systematic review is to create an overview of the literature on the comparison of navigated transcranial magnetic stimulation (nTMS) as a mapping tool to the current gold standard, which is (intraoperative) direct cortical stimulation (DCS) mapping. A search in the databases of PubMed, EMBASE, an...

    journal_title:Neurosurgical review

    pub_type: 杂志文章,评审

    doi:10.1007/s10143-020-01397-x

    authors: Jeltema HR,Ohlerth AK,de Wit A,Wagemakers M,Rofes A,Bastiaanse R,Drost G

    更新日期:2020-10-03 00:00:00

  • A meta-analysis of the effect of different neuroprotective drugs in management of patients with traumatic brain injury.

    abstract::Traumatic brain injury is a major problem worldwide. Our objective is to synthesize available evidence in the literature concerning the effectiveness of neuroprotective drugs (cerebrolysin, citicoline, and piracetam) on Glasgow outcome score (GOS), cognitive performance, and survival in traumatic brain injury patients...

    journal_title:Neurosurgical review

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s10143-016-0775-y

    authors: El Sayed I,Zaki A,Fayed AM,Shehata GM,Abdelmonem S

    更新日期:2018-04-01 00:00:00

  • Diseases of the vertebral arteries.

    abstract::Case reports and postmortem neuropathological findings of a wide spectrum of diseases affecting the vertebral arteries, in particular vasculitis, traumatic lesions, degenerative changes and congenital abnormalities, are discussed. ...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF00638894

    authors: Busch H,Bohl J,Mattern R,Meyermann R

    更新日期:1990-01-01 00:00:00

  • Morphometric analysis of untreated adult skulls in syndromic and nonsyndromic craniosynostosis.

    abstract::The aim of this study was to perform a morphometric analysis of untreated adult skulls displaying syndromic and nonsyndromic craniosynostosis. We analyzed, in detail, 42 adult craniosynostoses (18 scaphocephaly, 11 anterior plagiocephaly, 2 trigonocephaly, 9 oxycephaly, and 2 brachycephaly) from archeological (three s...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-007-0100-x

    authors: Weber J,Collmann H,Czarnetzki A,Spring A,Pusch CM

    更新日期:2008-04-01 00:00:00

  • Direct electrical stimulation of the optic radiation in patients with covered eyes.

    abstract::Direct electrical stimulation (DES) of the optic radiation (OR) during an awake tumor resection has been repeatedly reported. In all cases, visual function monitoring was performed in patients with open eyes which were looking at a picture. We report a new modification of the standard method, OR stimulation in patient...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-014-0535-9

    authors: Steňo A,Hollý V,Fabian M,Kuniak M,Timárová G,Steňo J

    更新日期:2014-07-01 00:00:00

  • Epidemiology, etiology, and types of severe adult brachial plexus injuries requiring surgical repair: systematic review and meta-analysis.

    abstract::The literature describing epidemiology, etiology, and types of serious brachial plexus injuries (BPIs) is sparse. The aim of this review was to investigate the epidemiological and etiopathogenetical data of serious BPIs undergoing surgical reconstruction. A systematic search was conducted from January 1985 to December...

    journal_title:Neurosurgical review

    pub_type: 杂志文章,评审

    doi:10.1007/s10143-018-1009-2

    authors: Kaiser R,Waldauf P,Ullas G,Krajcová A

    更新日期:2020-04-01 00:00:00

  • Surgery for posterior fossa meningioma: elevated postoperative cranial nerve morbidity discards aggressive tumor resection policy.

    abstract::Radical excision of meningioma is suggested to provide for the best tumor control rates. However, aggressive surgery for meningiomas located at the posterior cranial fossa may lead to elevated postoperative morbidity of adjacent cranial nerves which in turn worsens patients' postoperative quality of life. Therefore, w...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-020-01275-6

    authors: Schneider M,Schuss P,Güresir Á,Borger V,Vatter H,Güresir E

    更新日期:2020-02-27 00:00:00

  • Functional and anatomic aspects of the orbitotomy in craniofacial surgery.

    abstract::The orbitotomy has a central importance in craniofacial surgery. It is indicated for premature craniosynostoses, malformations and tumor surgery. The aim of the treatment is to correct functional disturbances and aesthetic impairments. Anatomical structures must be respected. Functional and anatomical aspects of the o...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF01787121

    authors: Mühling J,Collmann H,Reuther J,Sörensen N

    更新日期:1989-01-01 00:00:00

  • Cerebral capillary telangiectasias: a meta-analysis and review of the literature.

    abstract::As a result of their presumed benign natural history, cerebral capillary telangiectasias (CCTs) are infrequently addressed in the neurosurgical literature. We performed a comprehensive review of CCTs via the PubMed database to synthesize overall epidemiological, radiographic, natural history, and treatment results. Ac...

    journal_title:Neurosurgical review

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s10143-012-0435-9

    authors: Gross BA,Puri AS,Popp AJ,Du R

    更新日期:2013-04-01 00:00:00

  • Hemodynamic changes in a middle cerebral artery aneurysm at follow-up times before and after its rupture: a case report and a review of the literature.

    abstract::Hemodynamic parameters play a significant role in the development of cerebral aneurysms. Parameters such as wall shear stress (WSS) or velocity could change in time and may contribute to aneurysm growth and rupture. However, the hemodynamic changes at the rupture location remain unclear because it is difficult to obta...

    journal_title:Neurosurgical review

    pub_type: 杂志文章,评审

    doi:10.1007/s10143-016-0795-7

    authors: Sejkorová A,Dennis KD,Švihlová H,Petr O,Lanzino G,Hejčl A,Dragomir-Daescu D

    更新日期:2017-04-01 00:00:00

  • Prognostic significance of hematoma thickness to midline shift ratio in patients with acute intracranial subdural hematoma: a retrospective study.

    abstract::Acute intracranial subdural hematoma (ASDH) is commonly associated with a grave prognosis citing a high incidence of morbidity and mortality. The parameters to decide on surgical evacuation of the hematoma are sometimes controversial. In this study, we theorized that the ratio between maximal hematoma thickness and mi...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-017-0873-5

    authors: Moussa WMM,Khedr WM,Elwany AH

    更新日期:2018-04-01 00:00:00

  • Giant cavernous hemangiomas: report of three cases.

    abstract::Giant cavernous hemangiomas occur very rarely, and little has been reported about their behavior. In this case report three cavernous hemangiomas with a diametric measure between 6 cm and 7 cm and distinct features will be described. A 36-year-old female patient presented with headache and nausea. A CT scan disclosed ...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-006-0042-8

    authors: van Lindert EJ,Tan TC,Grotenhuis JA,Wesseling P

    更新日期:2007-01-01 00:00:00

  • Prognostic factors in civilian gunshot wounds to the head: a series of 110 surgical patients and brief literature review.

    abstract::This study was carried out to evaluate the early results and the prognostic factors affecting the outcome during the in-hospital stay of 110 patients with civilian gunshot wounds to the head admitted at the Hospital of Restauração, Recife, Brazil. Penetrating injury (66%) was the most prevalent type of wound encounter...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-012-0377-2

    authors: Ambrosi PB,Valença MM,Azevedo-Filho H

    更新日期:2012-07-01 00:00:00

  • Cerebral reperfusion in brain death of a newborn. Case report.

    abstract::A case of "sudden infant death" after 15 minutes of successful resuscitation of cardiovascular function is presented. While apnoic cranial nerve areflexia and electrocerebral silence persisted, angiography and transcranial Doppler sonography demonstrated nearly normal cerebral perfusion, which even increased day by da...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF00257815

    authors: Sanker P,Roth B,Frowein RA,Firsching R

    更新日期:1992-01-01 00:00:00

  • Intracranial pseudoaneurysm due to rupture of a saccular aneurysm mimicking a large partially thrombosed aneurysm ("ghost aneurysm"): radiological findings and therapeutic implications in two cases.

    abstract::Intracranial pseudoaneurysm formation due to ruptured non-traumatic saccular aneurysm is extremely rare. We experienced two cases of large pseudoaneurysm formation due to rupture of a saccular aneurysm. The neuroradiological ghost-like appearance of the aneurysms led to misdiagnoses as large partially thrombosed aneur...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-004-0336-7

    authors: Mori K,Kasuga C,Nakao Y,Yamamoto T,Maeda M

    更新日期:2004-10-01 00:00:00

  • Histopathological and molecular predictors of growth patterns and recurrence in craniopharyngiomas: a systematic review.

    abstract::Craniopharyngiomas (CPs) are rare, benign tumors derived from Rathke's pouch, known for their high recurrence rates and associated morbidity and mortality. Despite significant investigation on risk factors for recurrence, a lack of consensus persists. Recent research suggests that specific histopathological and molecu...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-018-0978-5

    authors: Coury JR,Davis BN,Koumas CP,Manzano GS,Dehdashti AR

    更新日期:2020-02-01 00:00:00

  • Management of cerebral vasospasm.

    abstract::Cerebral vasospasm is delayed narrowing of the large arteries of the circle of Willis occurring 4 to 14 days after aneurysmal subarachnoid hemorrhage (SAH). It is but one cause of delayed deterioration after SAH but, in general, is the most important potentially treatable cause of morbidity and mortality after SAH. De...

    journal_title:Neurosurgical review

    pub_type: 杂志文章,评审

    doi:10.1007/s10143-005-0013-5

    authors: Loch Macdonald R

    更新日期:2006-07-01 00:00:00

  • Humoral immunodeficiency syndrome in patients with severe head injury?

    abstract::Twenty patients with severe head injury were analysed as to whether they developed a humoral immunodeficiency syndrome. In spite of the fact that 75% developed pyogenic complications all patients showed a polyclonal humoral activation of their immune system with an increase in IgG, IgA, IgM and the complement factors....

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF01790685

    authors: Maerker-Alzer G,Beckmann H,Richard KE,Frowein RA

    更新日期:1989-01-01 00:00:00

  • Brain death: practicability of evoked potentials.

    abstract::Multimodally evoked potentials were registered in 85 patients who fulfilled the criteria for brain death. While somatosensory and visual evoked potentials have been found to be of limited value for the diagnosis of brain death, the stepwise abolition of brain stem auditory evoked potentials (BAEP) confirmed brain deat...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF00257800

    authors: Firsching R,Frowein RA,Wilhelms S,Buchholz F

    更新日期:1992-01-01 00:00:00

  • Papillary meningioma of the central nervous system: a SEER database analysis.

    abstract::Papillary meningioma (PM) is a rare central nervous system tumor. We aimed to analyze the characteristics and outcomes of patients with PM (WHO grade III) and identify risk factors that influence survival using the Surveillance, Epidemiology, and End Results (SEER) database. Clinical characteristics, tumor features, a...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-020-01449-2

    authors: Liu F,Tian Y,Zhou L

    更新日期:2021-01-08 00:00:00

  • Intra-operative hemorrhage due to hyperperfusion during direct revascularization surgery in an adult patient with moyamoya disease: a case report.

    abstract::Hemorrhagic complication is one of the notable surgical complications of the revascularization surgery for moyamoya disease (MMD). Cerebral hyperperfusion (CHP) has been considered as the underlying cause of this complication. It mostly occurs several days after surgery, but the intra-operative hemorrhage immediately ...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-017-0868-2

    authors: Uchida H,Endo H,Fujimura M,Endo T,Niizuma K,Tominaga T

    更新日期:2017-10-01 00:00:00

  • Large facial nerve schwannomas without facial palsy: case reports and review of the literature.

    abstract::Although approximately 30% of facial nerve schwannoma cases present with no facial palsy, a large facial nerve schwannoma extending to the middle and posterior cranial fossa quite rarely presents without facial palsy. The authors encountered two patients with large facial nerve schwannoma who presented with only heari...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/s10143-005-0381-x

    authors: Kubota Y,Kawamata T,Kubo O,Kasuya H,Muragaki Y,Hori T

    更新日期:2005-07-01 00:00:00

  • Percutaneous radiofrequency rhizotomy of lumbar spinal facets: the results of 46 cases.

    abstract::The results of percutaneous radiofrequency rhizotomy of lumbar spinal facets in 46 patients followed at least three months (mean 15 months) are reported and compared with those reported previously. Satisfactory pain relief three months after the procedure was achieved in 36.4 percent of patients without operations and...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF01138194

    authors: Göçer AI,Cetinalp E,Tuna M,Ildan F,Bağdatoğlu H,Haciyakupoğlu S

    更新日期:1997-01-01 00:00:00

  • Chronic subdural hematomas in adults: prognostic factors. Analysis of 70 cases.

    abstract::We did a prospective study of 70 adults with chronic subdural hematomas. We looked at the correlation between some aetiological, clinical, and radiological factors and outcome. The present analysis found a significant positive correlation of cephalea, isodense aspect of the hematoma at CT scan, and pulsatance of the e...

    journal_title:Neurosurgical review

    pub_type: 杂志文章

    doi:10.1007/BF00383875

    authors: Merlicco G,Pierangeli E,di Padova PL

    更新日期:1995-01-01 00:00:00