Abstract:
:Papillary meningioma (PM) is a rare central nervous system tumor. We aimed to analyze the characteristics and outcomes of patients with PM (WHO grade III) and identify risk factors that influence survival using the Surveillance, Epidemiology, and End Results (SEER) database. Clinical characteristics, tumor features, and outcomes of 108 PM patients included in the SEER database between 1990 and 2016 were retrieved. Risk factors related to prognosis of PM were assessed by Kaplan-Meier curves and the Cox proportional hazards model. All 108 patients, including 65 males and 43 females (1.5:1), with a median age of 52 years (range, 9 to > 85 years) had undergone surgical resection. Gross total resection (GTR) was achieved in 50%, and 50% underwent subtotal resection (STR). While 55.6% underwent postoperative radiation therapy, 48% did not. The median disease-specific survival (DSS) was 128 months, and the 5-year DSS rate was 77%. In multivariate analysis, age ≤ 52 years and GTR were both independently associated with higher probability of DSS (p = 0.033 and p = 0.029, respectively). Stratification analysis showed that postoperative radiotherapy had no significant impact on the DSS, irrespective of resection extent (p = 0.172). Our SEER analysis showed that age and extent of resection were prognostic factors for PM, but race, tumor size, gender, chemotherapy, and postoperative radiotherapy did not significantly impact DSS of PM patients. There was no significant improvement in survival of patients who underwent radiotherapy and GTR, or radiotherapy and STR, compared with GTR or STR alone.
journal_name
Neurosurg Revjournal_title
Neurosurgical reviewauthors
Liu F,Tian Y,Zhou Ldoi
10.1007/s10143-020-01449-2subject
Has Abstractpub_date
2021-01-08 00:00:00eissn
0344-5607issn
1437-2320pii
10.1007/s10143-020-01449-2pub_type
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journal_title:Neurosurgical review
pub_type: 临床试验,杂志文章
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abstract::Epidermoid cysts constitute less than 1% of intracranial tumors with the majority of them involving cerebellopontine angle (CPA). Although several mechanisms for cranial nerve dysfunction due to these tumors have been proposed, no direct evaluation for hyper- or hypoactive dysfunction has been done. In this case serie...
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abstract::Intradiploic epidermoid tumor of the occipital bone was presented. There were neither intracranial extensions nor neurologic deficits. The lesion started as a painless mass under the scalp. The total removal of the tumor was associated with a good prognosis. ...
journal_title:Neurosurgical review
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pub_type: 杂志文章
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journal_title:Neurosurgical review
pub_type: 杂志文章
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journal_title:Neurosurgical review
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journal_title:Neurosurgical review
pub_type: 杂志文章
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journal_title:Neurosurgical review
pub_type: 杂志文章
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journal_title:Neurosurgical review
pub_type: 杂志文章,评审
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journal_title:Neurosurgical review
pub_type: 杂志文章
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journal_title:Neurosurgical review
pub_type: 杂志文章,评审
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journal_title:Neurosurgical review
pub_type: 杂志文章,meta分析,评审
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pub_type: 杂志文章
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journal_title:Neurosurgical review
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journal_title:Neurosurgical review
pub_type: 杂志文章
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journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-007-0070-z
更新日期:2007-07-01 00:00:00
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journal_title:Neurosurgical review
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Neurosurgical review
pub_type: 杂志文章,评审
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