Abstract:
:The purpose of this study was to determine the effect of aspirin therapy discontinuation on intraoperative blood loss in spinal surgery. We searched Medline and Google Scholar 1946 to January 2017 inclusive for case-control studies, cohort studies, and controlled trials reporting intraoperative blood loss during spinal surgery in patients on pre-operative aspirin. Other outcome measures reported in the eligible studies were collected as secondary outcomes. Two reviewers independently screened and extracted data from each study. Five retrospective cohort and two case-control studies were eligible for inclusion. Of the 1173 patients identified, 587 patients were never on aspirin (Ax), 416 patients had aspirin discontinued before surgery (Ad), ranging from 3 to 10 days, and 170 patients had aspirin continued until surgery (Ac). Six out of seven studies reported no statistically significant difference in intraoperative blood loss irrespective of aspirin discontinuation. Meta-analysis was not possible due to high risk of bias. Of the secondary outcome measures, operative time and postoperative complications were most commonly reported. One of six studies evaluating operative time reported a significantly longer operative time in the Ad group compared with the Ac group. The overall risk of postoperative haematoma in Ax, Ad, and Ac groups is 0.2% (n/N = 1/587), 0.2% (n/N = 1/416), and 1.2% (n/N = 2/170), respectively. No study reported a statistically significant difference in postoperative complications. There is no strong evidence demonstrating a difference in intraoperative blood loss, operation time, and postoperative complications, irrespective of aspirin discontinuation. This is, however, based on a limited number of studies and higher-quality research is required to answer this question with a higher degree of confidence.
journal_name
Neurosurg Revjournal_title
Neurosurgical reviewauthors
Cheng A,Poon MTC,Demetriades AKdoi
10.1007/s10143-018-0945-1subject
Has Abstractpub_date
2018-10-01 00:00:00pages
1029-1036issue
4eissn
0344-5607issn
1437-2320pii
10.1007/s10143-018-0945-1journal_volume
41pub_type
杂志文章,meta分析,评审abstract::Surgery for intraventricular tumors remains a controversial and evolving field, with endoscopic resection becoming more popular. We present a series of nine consecutive cases of purely endoscopic resection of intraventricular tumors with the aid of an ultrasonic aspirator specific for neuroendoscopy. Nine patients (fi...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-018-1011-8
更新日期:2019-12-01 00:00:00
abstract::In 63 specimens, 74 aneurysms, and five other lesions, postmortem microsurgical and endoscopic inspection (PMI) was done. This work not only allowed for safe pathoanatomic findings, but moreover showed characteristics of a training method developed according to a model with clear standards. PMI gives training in: 1. U...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s101430100155
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abstract::Clinical practice guidelines (CPGs) play an important role in healthcare. The guideline development process should be precise and rigorous to ensure that the results are reproducible and not vague. To determine the quality of guidelines, the Appraisal of Guidelines and Research and Evaluation (AGREE) instrument was de...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-014-0569-z
更新日期:2015-01-01 00:00:00
abstract::Intracranial pseudoaneurysm formation due to ruptured non-traumatic saccular aneurysm is extremely rare. We experienced two cases of large pseudoaneurysm formation due to rupture of a saccular aneurysm. The neuroradiological ghost-like appearance of the aneurysms led to misdiagnoses as large partially thrombosed aneur...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-004-0336-7
更新日期:2004-10-01 00:00:00
abstract::The vasodilatory calcitonin gene-related peptide (CGRP) is excessively released after spontaneous subarachnoid hemorrhage (sSAH) and modulates psycho-behavioral function. In this pilot study, we prospectively analyzed the treatment-specific differences in the secretion of endogenous CGRP into cerebrospinal fluid (CSF)...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-020-01333-z
更新日期:2020-06-22 00:00:00
abstract::Stereotactic biopsies represent a routine neurosurgical procedure for the diagnosis of intracranial lymphomas and selected diffusely infiltrating gliomas. Acquisition of tissue samples that do not allow correct tumor typing and grading is, however, not uncommon. Five-aminolevulinic acid (5-ALA) has been shown to accum...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-012-0374-5
更新日期:2012-07-01 00:00:00
abstract::Epidermoid cysts constitute less than 1% of intracranial tumors with the majority of them involving cerebellopontine angle (CPA). Although several mechanisms for cranial nerve dysfunction due to these tumors have been proposed, no direct evaluation for hyper- or hypoactive dysfunction has been done. In this case serie...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-015-0684-5
更新日期:2016-04-01 00:00:00
abstract::The prognosis after evacuation of a chronic subdural hematoma is generally good, yet occasionally post-operative complications do occur. Intracerebral hematoma following such evacuation is rare and two cases are reported. It is suggested that this complication could be due to the disturbances of intracerebral vascular...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01790653
更新日期:1989-01-01 00:00:00
abstract::A neuroendoscopic biopsy is a minimally invasive and useful procedure for the diagnosis and initial management of tumor-associated hydrocephalus. We describe the nationwide investigation of the current status of neuroendoscopic biopsy for intra- and paraventricular tumors in children, as well as the treatment of tumor...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-015-0629-z
更新日期:2015-10-01 00:00:00
abstract::Acute management of deep-seated hematomas remains controversial. Since patients with these hematoma later tend to develop severe edema and necrosis around the lesion, when surgery is indicated it should be done as early as possible. The purpose of this study was to compare whether early surgical removal and conservati...
journal_title:Neurosurgical review
pub_type: 临床试验,杂志文章
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更新日期:2001-07-01 00:00:00
abstract::Von Hippel-Lindau disease (VHL) is a hereditary cancer syndrome caused by germline mutations of the VHL tumor suppressor gene. Major progress has been made in the last decade in both clinical and fundamental aspects of VHL. The VHL gene product, pVHL, has major and multiple functions: pVHL regulates not only first ang...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s101430050024
更新日期:2000-03-01 00:00:00
abstract::Case reports and postmortem neuropathological findings of a wide spectrum of diseases affecting the vertebral arteries, in particular vasculitis, traumatic lesions, degenerative changes and congenital abnormalities, are discussed. ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00638894
更新日期:1990-01-01 00:00:00
abstract::Endovascular management of cerebral aneurysms resulting in third nerve palsies has been proposed as an alternative to microsurgical clip ligation. Third nerve function recovery following endovascular treatment in a large patient population has not been evaluated. A literature search of MEDLINE, PubMed, and Cochrane da...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-007-0089-1
更新日期:2007-10-01 00:00:00
abstract::Histological, immunocytochemical, and biological features of 38 giant cell gliomas were investigated. The invasion of these tumors and its giant cells by histiocytes, lymphocytes, plasma cells, and especially by eosinophilic granulocytes is viewed as an immune response, which may explain a favorable clinical course. F...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01782050
更新日期:1987-01-01 00:00:00
abstract::Hemorrhagic complication is one of the notable surgical complications of the revascularization surgery for moyamoya disease (MMD). Cerebral hyperperfusion (CHP) has been considered as the underlying cause of this complication. It mostly occurs several days after surgery, but the intra-operative hemorrhage immediately ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-017-0868-2
更新日期:2017-10-01 00:00:00
abstract::Sinus pericranii is a rare vascular abnormality characterised by abnormal connections between the intra- and extracranial venous systems and is usually found in children. In most instances, a sinus pericranii presents as a soft scalp swelling that appears with the patient in the recumbent position and disappears in th...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-011-0325-6
更新日期:2012-01-01 00:00:00
abstract::A multidimensional concept of diagnosis and treatment of mental disorders is presented. Major contributions to basic research come from pharmacological experiments. Clinical outcome in treatment of endogenous depression can be assessed by rating scales and psychophysiological tests and correlated with the serum level ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01650030
更新日期:1980-01-01 00:00:00
abstract::Supplemental education is desirable for neurosurgical training, and the use of human cadaver specimen and virtual reality models is routine. An in vivo porcine training model for cranial neurosurgery was introduced in 2005, and our recent experience with this unique model is outlined here. For the first time, porcine ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-014-0572-4
更新日期:2015-01-01 00:00:00
abstract::Cavernous hemangiomas are the most frequently found primary tumors in the orbital region. They normally appear in adults. Diagnostic features in the majority of cases include protrusio bulbi and orbital enlargement. B-Scan and computed tomography/MRI are the prime diagnostic aids. We recommend surgical removal of thes...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/BF01794679
更新日期:1988-01-01 00:00:00
abstract::A new technique for interbody lumbar spondylodesis using a new cancellous metal, plug-shaped construct was performed in 35 cases with spondylolisthesis or lumbar instability. All of these patients have had severe low-back pain for years, some with radicular symptoms and had been treated unsuccessfully for years. In a ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00638889
更新日期:1990-01-01 00:00:00
abstract::Chemotherapy of malignant glioma has been discussed in relation to recent advances in experimental and clinical studies. It is now obvious that chemotherapy is of increasing importance in the multidisciplinary treatment of malignant gliomas. Survival time of patients was prolonged by intensive and prolonged chemothera...
journal_title:Neurosurgical review
pub_type: 临床试验,杂志文章,评审
doi:10.1007/BF01743285
更新日期:1984-01-01 00:00:00
abstract::Preoperative prediction of molecular information of lower-grade gliomas (LrGGs) helps to determine the overall treatment strategy as well as the initial surgical strategy. This study aimed to detect magnetic resonance imaging (MRI) texture parameters to predict the molecular signature of LrGGs using a commercially ava...
journal_title:Neurosurgical review
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doi:10.1007/s10143-019-01157-6
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abstract::Different disorders may produce irreducible atlanto-axial dislocation with compression of the ventral spinal cord. Among the surgical approaches available for a such condition, the transoral resection of the odontoid process is the most often used. The aim of this anatomical study is to demonstrate the possibility of ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-007-0084-6
更新日期:2007-07-01 00:00:00
abstract::Colloid cysts of the third ventricle are considered as benign lesions. The clinical manifestations are not clear in most of cases. Many treatment options are available and endoscopic removal of the cysts proves to be a very successful method especially if the lateral ventricles are moderately or severely dilated. Some...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-018-0956-y
更新日期:2019-03-01 00:00:00
abstract::Forty-four adult acromegalic patients carrying growth hormone-producing pituitary macroadenomas were investigated with neuroradiological and endocrinological techniques. Plasma growth hormone and somatomedin-C levels were repeatedly measured before surgical removal of tumors and during the follow-up period. Twenty-fiv...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01105562
更新日期:1997-01-01 00:00:00
abstract::Twenty-six patients with oculomotor nerve palsy due to cerebral aneurysms were examined. There were six males and twenty females with a mean age of 55 years. 25 of the 26 aneurysms were located at the junction of the internal carotid and the posterior communicating artery and one was at the junction of the basilar art...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01741485
更新日期:1989-01-01 00:00:00
abstract::The present study aimed to determine the clinical presentation, the multimodal interdisciplinary treatment strategies and outcome of posterior fossa arterio-venous malformations (AVMs) in our neurovascular centre. Fifty-three patients with a posterior fossa AVM were seen between 1998 and 2012 and analysed retrospectiv...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-014-0551-9
更新日期:2014-10-01 00:00:00
abstract::The purpose of this study is to describe our series of nine unclippable and uncoilable ruptured aneurysms in eight patients treated by microsurgical wrapping with autologous muscle. Records were retrospectively reviewed for rebleeding rate, morbidity and mortality, changes in size or the aneurysm's configurations, and...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-012-0408-z
更新日期:2013-01-01 00:00:00
abstract::We conducted a systematic review of the literature to evaluate the efficacy of various treatment modalities for intracranial aneurysms (IA) in patients with moyamoya disease (MMD) based on anatomical location of IA. A comprehensive review of studies documenting single cases or series of MMD patients with concomitant I...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-020-01307-1
更新日期:2020-05-08 00:00:00
abstract::A case of "sudden infant death" after 15 minutes of successful resuscitation of cardiovascular function is presented. While apnoic cranial nerve areflexia and electrocerebral silence persisted, angiography and transcranial Doppler sonography demonstrated nearly normal cerebral perfusion, which even increased day by da...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00257815
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