Contribution to the problem of giant cell astrocytomas.

Abstract:

:Histological, immunocytochemical, and biological features of 38 giant cell gliomas were investigated. The invasion of these tumors and its giant cells by histiocytes, lymphocytes, plasma cells, and especially by eosinophilic granulocytes is viewed as an immune response, which may explain a favorable clinical course. Fifty-three percent of the patients were younger than 45 years at the time of surgery. The average postoperative survival of 27.4 months was clearly longer than in glioblastoma. These biological features suggest a differentiation from glioblastoma multiforme. The classification of this entity as "monstrocellular astrocytoma" is proposed.

journal_name

Neurosurg Rev

journal_title

Neurosurgical review

authors

Müller W,Slowik F,Firsching R,Afra D,Sanker P

doi

10.1007/BF01782050

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

213-9

issue

3

eissn

0344-5607

issn

1437-2320

journal_volume

10

pub_type

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