Abstract:
:Growing evidence from recent studies have revealed that long non-coding RNA (lncRNA) might be a useful prognostic biomarker for glioma; we therefore conducted the current meta-analysis to evaluate prognostic and clinicopathological predictive value of lncRNA expression for glioma patients. Eligible studies were identified through multiple research strategies in PubMed, EMBASE, Web of Science, and Cochrane Library up to May 2017. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were utilized to calculate patient's survival. Fourteen eligible studies with 1415 patients were ultimately included in this meta-analysis. Our meta-analysis showed a significant association between high lncRNA expression level and OS in glioma patients (HR 2.09, 95% CI 1.68-2.58, P < 0.001). Subgroup analysis was conducted to explore the potential heterogeneity. As for clinicopathological parameters, lncRNA expression was significantly associated with tumor diameter (< 3 vs ≥ 3 cm, OR 0.39, 95% CI 0.27-0.56, P < 0.001; < 5 vs ≥ 5 cm, OR 0.56, 95% CI 0.34-0.92, P = 0.02), tumor grade (OR 0.21, 95% CI 0.13-0.34, P < 0.001), and Karnofsky Performance Status Scale (OR 2.52, 95% CI 1.54-4.11, P < 0.001). LncRNA may serve as a biomarker for prognosis and clinicopathological features in glioma patients.
journal_name
Neurosurg Revjournal_title
Neurosurgical reviewauthors
Li J,Liang R,Song C,Xiang Y,Liu Ydoi
10.1007/s10143-018-0965-xsubject
Has Abstractpub_date
2020-02-01 00:00:00pages
1-8issue
1eissn
0344-5607issn
1437-2320pii
10.1007/s10143-018-0965-xjournal_volume
43pub_type
杂志文章,meta分析abstract::Spinal cord or cauda equina compression (SCC) is an increasing challenge in clinical oncology due to a higher prevalence of long-term cancer survivors. Our aim was to determine the clinical relevance of SCC regarding patient outcome depending on different tumor entities and their anatomical localization (extradural/in...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-016-0790-z
更新日期:2017-07-01 00:00:00
abstract::Idiopathic normal pressure hydrocephalus is a hydrodynamic disorder whose etiology remains unclear. The diagnosis is mainly clinical and the traditional treatment is cerebrospinal fluid shunt diversion. With the introduction of modern management strategies, endoscopic third ventriculostomy has become a viable alternat...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-015-0685-4
更新日期:2016-10-01 00:00:00
abstract::Whereas previously the dissection of arteries leading to the brain was thought to be a rare occurrence, this diagnosis has been found more frequently in the last years as a result of newer imaging methods. Furthermore, in contrast to earlier opinions, there is a rather good prognosis for the recanalisation of the vess...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF02352070
更新日期:1992-01-01 00:00:00
abstract::The use of intraoperative MRI (iMRI) increases extent of resection in transsphenoidal pituitary surgery. Microsurgical and endoscopic techniques have been established as equal and standard surgical methods. The object of the current study was to evaluate the additional value of iMRI for resection of invasive pituitary...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-019-01102-7
更新日期:2019-09-01 00:00:00
abstract::To achieve local control of malignant glioma, we designed a postoperative stereotactic radiotherapy using a micro-multileaf collimator (micro-MLC). The purpose of this study was to clarify the feasibility of this treatment. The treatment was performed in six patients who met the following eligibility criteria: (1) sup...
journal_title:Neurosurgical review
pub_type: 临床试验,杂志文章
doi:10.1007/s101430100185
更新日期:2002-06-01 00:00:00
abstract::Pediatric cortical ependymomas (CEs) are rare; the clinical features and optimal treatment remain ill-defined. We aimed to clarify the clinical characteristics and outcome of pediatric CEs based on institutional series and literature review. Thirteen children with CEs from our department were included in the present s...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-020-01336-w
更新日期:2020-06-30 00:00:00
abstract::In spite of recent advancements in the management of ruptured aneurysm, there are still controversies as to how to threat the patients in serious conditions, one of these concerning whether to operate patients admitted with symptomatic vasospasm (vasospasm on admission) and when. While early surgery may protect patien...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00417662
更新日期:1995-01-01 00:00:00
abstract::Based on extensive personal experiences during the past three decades, a review is given on infections and infestations of the central nervous system, which are found in India and in other tropical and subtropical areas. Besides the main disease such as tuberculosis, pyogenic infections and parasitic infestations, rar...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/BF01742760
更新日期:1983-01-01 00:00:00
abstract::Patients infected with the human immunodeficiency virus (HIV) or suffering from acquired immunodeficiency syndrome (AIDS) are now surviving for longer periods of time secondary to improvements in medical management. As the classical causes of morbidity and mortality in this patient population have come under better co...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-004-0371-4
更新日期:2005-04-01 00:00:00
abstract::The prognosis after evacuation of a chronic subdural hematoma is generally good, yet occasionally post-operative complications do occur. Intracerebral hematoma following such evacuation is rare and two cases are reported. It is suggested that this complication could be due to the disturbances of intracerebral vascular...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01790653
更新日期:1989-01-01 00:00:00
abstract::It is well known that radiation can induce meningiomas. These tumors usually arise in patients with a history of low-dose radiation to the scalp for treatment of tinea capitis or high-dose radiation for a previous brain tumor. Radiation-associated meningiomas (RAMs) morphologically resemble their spontaneously arising...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-004-0366-1
更新日期:2005-04-01 00:00:00
abstract::The purpose of this paper is to provide a comprehensive review encompassing the syndromes associated with the lower cranial nerves (LCNs). We will discuss the anatomy of some of these syndromes and the historical contributors after whom they were named. The LCNs can be affected individually or in combination, since th...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-020-01344-w
更新日期:2020-07-08 00:00:00
abstract::Patients with aneurysmal subarachnoid hemorrhage (SAH) are frequently complicated by acute cardiac dysfunctions, including cardiac wall motion abnormality (WMA). Massive release of catecholamine into the systemic circulation after aneurysmal rupture is believed to result in WMA, and poor-grade SAH seems to be the most...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-012-0424-z
更新日期:2013-04-01 00:00:00
abstract::Different disorders may produce irreducible atlanto-axial dislocation with compression of the ventral spinal cord. Among the surgical approaches available for a such condition, the transoral resection of the odontoid process is the most often used. The aim of this anatomical study is to demonstrate the possibility of ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-007-0084-6
更新日期:2007-07-01 00:00:00
abstract::Cerebral infarction (CI) associated with clipping of unruptured intracranial aneurysms (UIAs) has not been completely studied. The role of individual and operative characteristics is not known, and the risk of silent CI has not been well described. To determine the incidence, risk factors, and clinical outcome of post...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-017-0913-1
更新日期:2018-04-01 00:00:00
abstract::Surgical resections of meningiomas, the most common intracranial tumor in adults, can only be curative if radical resection is achieved. Potentially, the extent of resection could be improved, especially in complex and/or high-grade meningiomas by fluorescence-guided surgery using 5-aminolevulinic acid (5-ALA), indocy...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-018-01062-4
更新日期:2019-12-01 00:00:00
abstract::Vasospasm is a major contributor to morbidity and mortality in aneurysmal subarachnoid hemorrhage (SAH), with inflammation playing a key role in its pathophysiology. Myeloperoxidase (MPO), an inflammatory marker, was examined as a potential marker of vasospasm in patients with SAH. Daily serum samples from patients wi...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-012-0375-4
更新日期:2012-07-01 00:00:00
abstract::Cavernous hemangiomas are the most frequently found primary tumors in the orbital region. They normally appear in adults. Diagnostic features in the majority of cases include protrusio bulbi and orbital enlargement. B-Scan and computed tomography/MRI are the prime diagnostic aids. We recommend surgical removal of thes...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/BF01794679
更新日期:1988-01-01 00:00:00
abstract::CSF hydrocele as a complication of migration or extrusion of the peritoneal end of the V-P shunt has rarely been reported. Here the case of a 6 month old infant, born at 28 weeks gestational age, is reported. The baby was noted to have scrotal swelling, exacerbated by crying, two months after insertion of ventriculope...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00313040
更新日期:1991-01-01 00:00:00
abstract::We collected data to provide evidence that orbital cavernous malformations (CMs) are histopathologically, neuroradiologically, and clinically different from cerebral CMs and may represent a distinct entity. In this study, the main clinical, histopathological and radiological characteristics of 19 patients (11 females ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-006-0055-3
更新日期:2007-01-01 00:00:00
abstract::The management of posterior cranial fossa meningioma [PCFM] is challenging and many neurosurgeons advise gamma knife radiosurgery [GKRS] as a modality for its upfront or adjuvant treatment. Due to the varying radiosurgical response based on lesion location, tumor biology, and radiation dosage, we performed a pioneer a...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-019-01144-x
更新日期:2020-08-01 00:00:00
abstract::Intradiploic epidermoid tumor of the occipital bone was presented. There were neither intracranial extensions nor neurologic deficits. The lesion started as a painless mass under the scalp. The total removal of the tumor was associated with a good prognosis. ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00418080
更新日期:1996-01-01 00:00:00
abstract::200 stereotactic biopsies were evaluated. The validity of the intraoperative histopathological results were compared with the final diagnosis using conventional embedding and staining techniques. Further comparison between the histology of the biopsy and the post mortem or open operative findings were possible in 41 c...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF00309989
更新日期:1994-01-01 00:00:00
abstract::Otogenic brain abscesses are a significant cause of mortality and morbidity in developing countries. Usually they occur either by distant thrombophlebitis of cerebral veins or by direct extension in an unsafe type of chronic suppurative otitis media. This case of cerebellar abscess was prepared for surgical excision, ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/BF01111489
更新日期:1998-01-01 00:00:00
abstract::Human malignant gliomas arise from neural progenitor cells and/or dedifferentiated astrocytes. By now, they are genetically so well characterized that several murine glioma models have emerged that faithfully reiterate the typical histological features of the disease. In experimental animals, only one or two elements ...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-003-0267-8
更新日期:2003-07-01 00:00:00
abstract::Rare tumors with anecdotal reportage, oculomotor schwannomas are most often seen in the oculomotor cistern close to the anterior clinoidal region. Adding to the small series of reported cases of this unusual lesion, we report two male patients in their second decade who presented with different degrees of oculomotor p...
journal_title:Neurosurgical review
pub_type: 杂志文章,评审
doi:10.1007/s10143-011-0344-3
更新日期:2012-01-01 00:00:00
abstract::Microcystic meningioma (MM) is a rare subtype of intracranial meningiomas, with clinical and radiologic features not well characterized in the literature. Based on our experience, we propose a classification system of intracranial MMs. We reviewed the medical records, radiographic studies, and operative notes of a gro...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-018-0982-9
更新日期:2019-06-01 00:00:00
abstract::The apparent diffusion coefficient (ADC) on diffusion-weighted imaging (DWI) plays an important role in diagnosing intracranial tumors and predicting the histopathological grade of the tumor. However, the differences in the ADC values between craniopharyngiomas and germ cell tumors (GCTs) have not been clarified. We t...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-015-0660-0
更新日期:2016-04-01 00:00:00
abstract::The spinal nerve can be pinched between the transverse process of the fifth lumbar vertebra and the sacral ala. The patients are divided into two types: elderly persons with degenerative scoliosis and somewhat younger adults with isthmic spondylolisthesis. For the first time, we describe extraforaminal impingement of ...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-010-0300-7
更新日期:2010-04-01 00:00:00
abstract::5-aminolevulinic acid (5-ALA) is a natural precursor of protoporphyrin IX (PP IX), which possesses fluorescent properties and is more intensively accumulated in tumor cells than in normal tissue. Therefore, the use of 5-ALA in the surgical treatment of intracranial tumors, particularly gliomas, has gained popularity i...
journal_title:Neurosurgical review
pub_type: 杂志文章
doi:10.1007/s10143-015-0697-0
更新日期:2016-07-01 00:00:00